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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Colonization, safety, and tolerability study of the Streptococcus salivarius 24SMBc nasal spray for its application in upper respiratory tract infections
- 2015-07-24
- Clinical Trial · n = 20
- European Journal of Clinical Microbiology & Infectious Diseases 34(10)
- - M. Santagati
  - M. Scillato
  - N. Muscaridola
  - V. Metoldo
  - I. Mantia
  - S. Stefani
- PubMed: 26205666
- DOI: 10.1007/s10096-015-2454-2
4 Insights on
- High evidence
- Rigorous Journal
Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota.
- 2015-07-23
- Allergology International 63(4)
- - T. Enomoto
  - M. Sowa
  - Kei-ichi Nishimori
  - S. Shimazu
  - A. Yoshida
  - Kazuko Yamada
  - F. Furukawa
  - T. Nakagawa
  - N. Yanagisawa
  - N. Iwabuchi
  - T. Odamaki
  - F. Abe
  - J. Nakayama
  - J. Xiao
- PubMed: 25056226
- DOI: 10.2332/allergolint.13-OA-0683
3 Insights on
- Low evidence
- Highly Cited
Lactobacillus plantarum NCU116 improves liver function, oxidative stress and lipid metabolism in rats with high fat diet induced non-alcoholic fatty liver disease.
- 2015-07-17
- Food Funct. 5(12)
- - Chuan Li
  - Shaoping Nie
  - K. Zhu
  - Q. Ding
  - Chang Li
  - T. Xiong
  - M. Xie
- PubMed: 25317840
- DOI: 10.1039/c4fo00549j
7 Insights on
- Low evidence
- Highly Cited
Survival and Metabolic Activity of Pediocin Producer Pediococcus acidilactici UL5: Its Impact on Intestinal Microbiota and Listeria monocytogenes in a Model of the Human Terminal Ileum
- 2015-07-11
- Microbial Ecology 72(4)
- - B. Fernandez
  - P. Savard
  - I. Fliss
- PubMed: 26162534
- DOI: 10.1007/s00248-015-0645-0
1 Insight on
- Reduced Listeria Monocytogenes Population
- Low evidence
- Rigorous Journal
Bifidobacterium pseudocatenulatum CECT 7765 Reduces Obesity-Associated Inflammation by Restoring the Lymphocyte-Macrophage Balance and Gut Microbiota Structure in High-Fat Diet-Fed Mice
- 2015-07-10
- RCT
- PLOS ONE 10(7)
- - Á. Moya-Pérez
  - Alexander Neef
  - Y. Sanz
- PubMed: 26161548
- DOI: 10.1371/journal.pone.0126976
6 Insights on
- Low evidence
- Highly Cited
- Rigorous Journal
- Animal Study
Probiotic Lactobacillus rhamnosus GG therapy and microbiological programming in infantile colic: a randomized, controlled trial.
- 2015-07-07
- RCT · n = 30
- Pediatric research 78(4)
- - Anna Pärtty
  - Liisa Lehtonen
  - Marko Kalliomäki
  - Seppo Salminen
  - Erika Isolauri
- PubMed: 26151493
- DOI: 10.1038/pr.2015.127
2 Insights on
- Reduced Crying Time
- Reduced Crying
- High evidence
Vaginal colonisation by probiotic lactobacilli and clinical outcome in women conventionally treated for bacterial vaginosis and yeast infection
- 2015-07-03
- BMC Infectious Diseases 15(1)
- - S. Pendharkar
  - E. Brandsborg
  - L. Hammarström
  - H. Marcotte
  - P. Larsson
- PubMed: 26137971
- DOI: 10.1186/s12879-015-0971-3
5 Insights on
- Moderate evidence
- Highly Cited
- Rigorous Journal
Effects of dietary supplementation with lysine-yielding Bacillus subtilis on gut morphology, cecal microflora, and intestinal immune response of Linwu ducks.
- 2015-07-01
- RCT
- Journal of Animal Science 93(7)
- - Y. Xing
  - S. Wang
  - J. Fan
  - A. Oso
  - S. W. Kim
  - D. Xiao
  - T. Yang
  - G. Liu
  - G. Jiang
  - Z. Li
  - L. Li
  - B. Zhang
- PubMed: 26440014
- DOI: 10.2527/jas.2014-8090
7 Insights on
- High evidence
- Rigorous Journal
Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomised controlled trial
- 2015-06-19
- RCT
- Journal of Nutritional Science 4
- - J. Minami
  - S. Kondo
  - N. Yanagisawa
  - T. Odamaki
  - J. Xiao
  - F. Abe
  - S. Nakajima
  - Yukie Hamamoto
  - Sanae Saitoh
  - T. Shimoda
- PubMed: 26090097
- DOI: 10.1017/jns.2015.5
7 Insights on
- High evidence
- Highly Cited
Bifidobacterium breve alters immune function and ameliorates DSS-induced inflammation in weanling rats
- 2015-06-17
- Clinical Trial
- Pediatric Research 78(4)
- - H. Izumi
  - M. Minegishi
  - Yohei Sato
  - Takashi Shimizu
  - K. Sekine
  - M. Takase
- PubMed: 26083761
- DOI: 10.1038/pr.2015.115
6 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept
- 2015-06-17
- RCT · n = 21
- Diabetes Care 38(10)
- - M. Simon
  - K. Strassburger
  - B. Nowotny
  - H. Kolb
  - P. Nowotny
  - V. Burkart
  - F. Zivehe
  - J. Hwang
  - P. Stehle
  - G. Pacini
  - B. Hartmann
  - J. Holst
  - C. Mackenzie
  - L. Bindels
  - I. Martínez
  - J. Walter
  - B. Henrich
  - N. Schloot
  - M. Roden
- PubMed: 26084343
- DOI: 10.2337/dc14-2690
11 Insights on
- High evidence
- Highly Cited
Lactobacillus reuteri DSM 17938 as a Probiotic for Preterm Neonates: A Strain-Specific Systematic Review.
- 2015-06-09
- Systematic Review
- Journal of Parenteral and Enteral Nutrition 40(6)
- - G. Athalye-Jape
  - Shripada C Rao
  - S. Patole
- PubMed: 26059900
- DOI: 10.1177/0148607115588113
20 Insights on
- High evidence
Anti-diabetic and Anti-hyperlipidemic Effects and Safety of Salacia reticulata and Related Species.
- 2015-05-31
- Review
- Phytotherapy research : PTR 29(7)
- - Sidney J Stohs
  - Sidhartha Ray
- PubMed: 26031882
- DOI: 10.1002/ptr.5382
4 Insights on
- Low evidence
Lactobacillus rhamnosus GG Reverses Insulin Resistance but Does Not Block Its Onset in Diet-Induced Obese Mice.
- 2015-05-28
- Clinical Trial
- Journal of Microbiology and Biotechnology 25(5)
- - Kun-Young Park
  - Bobae Kim
  - C. Hyun
- PubMed: 25433553
- DOI: 10.4014/JMB.1409.09016
2 Insights on
- Improved Adiposity Biomarkers
- Improved Insulin Sensitivity
- Low evidence
- Animal Study
Invasive Saccharomyces cerevisiae in a liver transplant patient: case report and review of infection in transplant recipients
- 2015-05-26
- Case Report · n = 1
- Transplant Infectious Disease 17(3)
- - K. Popiel
  - P. Wong
  - M. J. Lee
  - M. Langelier
  - D. Sheppard
  - D. Vinh
- PubMed: 25827213
- DOI: 10.1111/tid.12384
1 Insight on
- Occurrence of Fungemia
- Low evidence
Black cohosh improves objective sleep in postmenopausal women with sleep disturbance.
- 2015-05-22
- RCT · n = 42
- Climacteric : the journal of the International Menopause Society 18(4)
- - K Jiang
  - Y Jin
  - L Huang
  - S Feng
  - X Hou
  - B Du
  - J Zheng
  - L Li
- PubMed: 26000551
- DOI: 10.3109/13697137.2015.1042450
5 Insights on
- High evidence
Towards a better understanding of Lactobacillus rhamnosus GG - host interactions
- 2015-05-15
- Microbial Cell Factories 13(Suppl 1)
- - M. Segers
  - S. Lebeer
- PubMed: 25186587
- DOI: 10.1186/1475-2859-13-S1-S7
4 Insights on
- Low evidence
- Highly Cited
Commensal Streptococcus salivarius Modulates PPARγ Transcriptional Activity in Human Intestinal Epithelial Cells
- 2015-05-06
- PLOS ONE 10(5)
- - Benoît Couvigny
  - Tomas de Wouters
  - Ghalia Kaci
  - Elsa Jacouton
  - C. Delorme
  - J. Doré
  - P. Renault
  - H. Blottière
  - É. Guédon
  - N. Lapaque
- PubMed: 25946041
- DOI: 10.1371/journal.pone.0125371
2 Insights on
- Improved Lipid Metabolism
- Regulated Inflammation
- Low evidence
- Rigorous Journal
Immunomodulatory Effects of Lactobacillus salivarius LS01 and Bifidobacterium breve BR03, Alone and in Combination, on Peripheral Blood Mononuclear Cells of Allergic Asthmatics
- 2015-05-04
- Allergy, Asthma & Immunology Research 7(4)
- - L. Drago
  - E. De Vecchi
  - A. Gabrieli
  - R. De Grandi
  - Marco Toscano
- PubMed: 25749784
- DOI: 10.4168/aair.2015.7.4.409
2 Insights on
- Reduced Pro-Inflammatory Cytokines
- Increased IL-10 Production
- Low evidence
Protective Effects of a Novel Probiotic Strain of Lactobacillus plantarum JSA22 from Traditional Fermented Soybean Food Against Infection by Salmonella enterica Serovar Typhimurium.
- 2015-04-28
- Journal of Microbiology and Biotechnology 25(4)
- - J. Eom
  - Jin Song
  - H. Choi
- PubMed: 25639720
- DOI: 10.4014/JMB.1501.01006
11 Insights on
- Low evidence
Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1, and Bifidobacterium longum MM-2 Ingestion Induces a Less Inflammatory Cytokine Profile and a Potentially Beneficial Shift in Gut Microbiota in Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study
- 2015-04-24
- RCT · n = 32
- Journal of the American College of Nutrition 34(6)
- - Samuel J. Spaiser
  - T. Culpepper
  - C. Nieves
  - M. Ukhanova
  - V. Mai
  - S. Percival
  - M. Christman
  - B. Langkamp-Henken
- PubMed: 25909149
- DOI: 10.1080/07315724.2014.983249
10 Insights on
- High evidence
Modulation of the host response by probiotic Lactobacillus brevis CD2 in experimental gingivitis.
- 2015-04-20
- RCT · n = 34
- Oral Diseases 21(6)
- - Jae-Kwan Lee
  - Kim Sj
  - Ko Sh
  - A. Ouwehand
  - Ma Ds
- PubMed: 25720615
- DOI: 10.1111/odi.12332
2 Insights on
- Reduced Nitric Oxide Production
- Reduced Gingival Inflammation
- High evidence
Effects of Oral Administration of Lactobacillus acidophilus L-92 on the Symptoms and Serum Cytokines of Atopic Dermatitis in Japanese Adults: A Double-Blind, Randomized, Clinical Trial
- 2015-04-16
- RCT · n = 49
- International Archives of Allergy and Immunology 165(4)
- - Y. Inoue
  - T. Kambara
  - Naoko Murata
  - J. Komori-Yamaguchi
  - S. Matsukura
  - Yukitoshi Takahashi
  - Z. Ikezawa
  - M. Aihara
- PubMed: 25660281
- DOI: 10.1159/000369806
3 Insights on
- High evidence
Effects of Bifidobacterium supplementation on intestinal microbiota composition and the immune response in healthy infants
- 2015-04-06
- RCT · n = 300
- World Journal of Pediatrics 12(2)
- - Bingbing Wu
  - Yi Yang
  - Xiu Xu
  - Weiping Wang
- PubMed: 25846071
- DOI: 10.1007/s12519-015-0025-3
2 Insights on
- Improved Immune Response
- Improved Intestinal Microbial Composition
- High evidence
- Large Human Trial
Applications of Microencapsulated Bifidobacterium Longum with Eleutherine Americana in Fresh Milk Tofu and Pineapple Juice
- 2015-04-03
- Nutrients 7(4)
- - A. Phoem
  - S. Chanthachum
  - S. Voravuthikunchai
- PubMed: 25854832
- DOI: 10.3390/nu7042469
5 Insights on
- Moderate evidence
Effect of iron on the probiotic properties of the vaginal isolate Lactobacillus jensenii CECT 4306.
- 2015-04-01
- Microbiology 161(4)
- - Rebeca Martín
  - B. Sánchez
  - M. Urdaci
  - P. Langella
  - J. Suárez
  - L. Bermúdez-Humarán
- PubMed: 25635270
- DOI: 10.1099/mic.0.000044
1 Insight on
- Increased Anti-Inflammatory Cytokine Levels
- Low evidence
Effect of Long-Term Consumption of Lactobacillus paracasei SD1 on Reducing Mutans streptococci and Caries Risk: A Randomized Placebo-Controlled Trial
- 2015-04-01
- RCT · n = 122
- Dentistry Journal 3(2)
- - R. Teanpaisan
  - S. Piwat
  - S. Tianviwat
  - B. Sophatha
  - Thanyanan Kampoo
- PubMed: 29567924
- DOI: 10.3390/dj3020043
9 Insights on
- High evidence
- Rigorous Journal
A lactose fermentation product produced by Lactococcus lactis subsp. lactis, acetate, inhibits the motility of flagellated pathogenic bacteria.
- 2015-04-01
- Microbiology 161(4)
- - Shuichi Nakamura
  - Yusuke V. Morimoto
  - S. Kudo
- PubMed: 25573770
- DOI: 10.1099/mic.0.000031
4 Insights on
- Low evidence
Assessment of probiotic, antifungal and cholesterol lowering properties of Pediococcus pentosaceus KCC-23 isolated from Italian ryegrass.
- 2015-03-21
- Journal of the Science of Food and Agriculture 96(2)
- - S. Ilavenil
  - M. Vijayakumar
  - D. H. Kim
  - M. Valan Arasu
  - Hyung-Su Park
  - S. Ravikumar
  - K. Choi
- PubMed: 25655225
- DOI: 10.1002/jsfa.7128
4 Insights on
- Low evidence
- Rigorous Journal
Use of bacteriocin‐producing, probiotic strain Enterococcus faecium AL41 to control intestinal microbiota in farm ostriches
- 2015-03-20
- RCT · n = 92
- Letters in Applied Microbiology 60(6)
- - A. Lauková
  - A. Kandričáková
  - J. Ščerbová
- PubMed: 25732357
- DOI: 10.1111/lam.12409
1 Insight on
- Reduced Harmful Gut Bacteria
- Low evidence
- Animal Study