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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Trace minerals intake: Risks and benefits for cardiovascular health.
- 2017-12-13
- Review
- Critical reviews in food science and nutrition 59(8)
- - Noushin Mohammadifard
  - Karin H Humphries
  - Carolyn Gotay
  - Guillermo Mena-Sánchez
  - Jordi Salas-Salvadó
  - Ahmad Esmaillzadeh
  - Andrew Ignaszewski
  - Nizal Sarrafzadegan
- PubMed: 29236516
- DOI: 10.1080/10408398.2017.1406332
1 Insight on
- Reduced Cardiovascular Event Risk
- Moderate evidence
- Highly Cited
Freeze-dried Lactobacillus plantarum 299v increases iron absorption in young females—Double isotope sequential single-blind studies in menstruating women
- 2017-12-13
- RCT · n = 42
- PLOS ONE 12(12)
- - M. Hoppe
  - G. Önning
  - L. Hulthén
- PubMed: 29236734
- DOI: 10.1371/journal.pone.0189141
1 Insight on
- Improved Iron Absorption
- High evidence
- Rigorous Journal
Effect of Lactobacillus gasseri BNR17 on irritable bowel syndrome: a randomized, double-blind, placebo-controlled, dose-finding trial
- 2017-12-12
- RCT · n = 55
- Food Science and Biotechnology 27(3)
- - J. Y. Kim
  - Y. Park
  - H. Lee
  - M. Park
  - O. Kwon
- PubMed: 30263811
- DOI: 10.1007/s10068-017-0296-7
3 Insights on
- High evidence
Omics of bifidobacteria: research and insights into their health-promoting activities.
- 2017-12-06
- Biochemical Journal 474(24)
- - F. Bottacini
  - D. van Sinderen
  - M. Ventura
- PubMed: 29212851
- DOI: 10.1042/BCJ20160756
2 Insights on
- Improved Gut Health
- Improved Gut Microbiome Composition
- Low evidence
- Highly Cited
Bifidobacteria and Their Molecular Communication with the Immune System
- 2017-12-04
- Frontiers in Microbiology 8
- - L. Ruiz
  - S. Delgado
  - P. Ruas-Madiedo
  - B. Sánchez
  - A. Margolles
- PubMed: 29255450
- DOI: 10.3389/fmicb.2017.02345
4 Insights on
- Low evidence
- Highly Cited
Probiotic Bacillus coagulans GBI-30, 6086 Improves Protein Absorption and Utilization
- 2017-12-01
- Review
- Probiotics and Antimicrobial Proteins 10(4)
- - R. Jäger
  - M. Purpura
  - S. Farmer
  - H. Cash
  - D. Keller
- PubMed: 29196920
- DOI: 10.1007/s12602-017-9354-y
2 Insights on
- Improved Protein Absorption
- Improved Protein Utilization
- Moderate evidence
- Highly Cited
Effects of artichoke leaf extract supplementation on metabolic parameters in women with metabolic syndrome: Influence of TCF7L2-rs7903146 and FTO-rs9939609 polymorphisms.
- 2017-11-29
- RCT · n = 50
- Phytotherapy research : PTR 32(1)
- - Khatereh Rezazadeh
  - Mohammad Rahmati-Yamchi
  - Leila Mohammadnejad
  - Mehrangiz Ebrahimi-Mameghani
  - Abbas Delazar
- PubMed: 29193419
- DOI: 10.1002/ptr.5951
1 Insight on
- Reduced Triglyceride Levels
- High evidence
Newly Isolated Lactobacilli strains from Algerian Human Vaginal Microbiota: Lactobacillus fermentum Strains Relevant Probiotic’s Candidates
- 2017-11-28
- Probiotics and Antimicrobial Proteins 11(1)
- - Liza Ouarabi
  - Y. Chait
  - H. Seddik
  - D. Drider
  - F. Bendali
- PubMed: 29185234
- DOI: 10.1007/s12602-017-9360-0
2 Insights on
- Reduced Vaginal Pathogens
- Adherence to Vaginal Mucosa
- Low evidence
Effect of Lactobacillus rhamnosus on the response of Galleria mellonella against Staphylococcus aureus and Escherichia coli infections
- 2017-11-24
- Clinical Trial
- Archives of Microbiology 200(3)
- - A. L. Jorjão
  - F. E. Oliveira
  - M. V. P. Leão
  - A. O. Jorge
  - L. D. Oliveira
- PubMed: 29177947
- DOI: 10.1007/s00203-017-1441-7
8 Insights on
- Low evidence
- Animal Study
Surface Proteins of Lactococcus lactis: Bacterial Resources for Muco-adhesion in the Gastrointestinal Tract
- 2017-11-23
- Frontiers in Microbiology 8
- - M. Mercier-Bonin
  - M. Chapot-Chartier
- PubMed: 29218032
- DOI: 10.3389/fmicb.2017.02247
1 Insight on
- Reduced Inflammation
- Low evidence
Evaluation of antioxidative and diabetes-preventive properties of an ancient grain, KAMUT® khorasan wheat, in healthy volunteers.
- 2017-11-16
- RCT · n = 30
- European journal of nutrition 58(1)
- - Caterina Trozzi
  - Francesca Raffaelli
  - Arianna Vignini
  - Laura Nanetti
  - Rosaria Gesuita
  - Laura Mazzanti
- PubMed: 29143934
- DOI: 10.1007/s00394-017-1579-8
3 Insights on
- High evidence
- Rigorous Journal
Bifidobacterium Infantis Ameliorates Chemotherapy-Induced Intestinal Mucositis Via Regulating T Cell Immunity in Colorectal Cancer Rats
- 2017-11-16
- RCT · n = 30
- Cellular Physiology and Biochemistry 42(6)
- - Hui Mi
  - Yan Dong
  - Bin Zhang
  - Haonan Wang
  - C. Peter
  - Ping Gao
  - H. Fu
  - Yajie Gao
- PubMed: 28848081
- DOI: 10.1159/000480005
1 Insight on
- Reduced Intestinal Mucositis Severity
- Low evidence
- Animal Study
Effect of a Lactobacillus Salivarius Probiotic on a Double-Species Streptococcus Mutans and Candida Albicans Caries Biofilm
- 2017-11-14
- Nutrients 9(11)
- - W. Krzyściak
  - D. Kościelniak
  - M. Papież
  - P. Vyhouskaya
  - K. Zagórska-Świeży
  - Iwona Kołodziej
  - B. Bystrowska
  - A. Jurczak
- PubMed: 29135948
- DOI: 10.3390/nu9111242
4 Insights on
- High evidence
- Highly Cited
Effect of Varying Doses of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Exposure Among Patients With Peanut Sensitivity: A Randomized Clinical Trial.
- 2017-11-14
- RCT · n = 221
- JAMA 318(18)
- - Hugh A Sampson
  - Wayne G Shreffler
  - William H Yang
  - Gordon L Sussman
  - Terri F Brown-Whitehorn
  - Kari C Nadeau
  - Amarjit S Cheema
  - Stephanie A Leonard
  - Jacqueline A Pongracic
  - Christine Sauvage-Delebarre
  - Amal H Assa'ad
  - Frederic de Blay
  - J Andrew Bird
  - Stephen A Tilles
  - Franck Boralevi
  - Thierry Bourrier
  - Jacques Hébert
  - Todd D Green
  - Roy Gerth van Wijk
  - André C Knulst
  - Gisèle Kanny
  - Lynda C Schneider
  - Marek L Kowalski
  - Christophe Dupont
- PubMed: 29136445
- DOI: 10.1001/jama.2017.16591
1 Insight on
- Increased Peanut Protein Eliciting Dose
- High evidence
- Large Human Trial
- Highly Cited
- Rigorous Journal
Production of probiotic bovine salami using Lactobacillus plantarum 299v as adjunct.
- 2017-11-13
- Journal of the science of food and agriculture 98(6)
- - Giuseppe Blaiotta
  - Nicoletta Murru
  - Alessandro Di Cerbo
  - Raffaele Romano
  - Maria Aponte
- PubMed: 28990658
- DOI: 10.1002/jsfa.8717
2 Insights on
- Improved Microbiological Safety of Fermented Sausage
- Improved Lactobacillus Plantarum 299v Survival During Storage
- Low evidence
Lactobacillus bulgaricus, Lactobacillus rhamnosus and Lactobacillus paracasei Attenuate Salmonella Enteritidis, Salmonella Heidelberg and Salmonella Typhimurium Colonization and Virulence Gene Expression In Vitro
- 2017-11-09
- International Journal of Molecular Sciences 18(11)
- - M. S. Muyyarikkandy
  - M. Amalaradjou
- PubMed: 29120368
- DOI: 10.3390/ijms18112381
1 Insight on
- Reduced Salmonella Colonization
- Low evidence
Antibacterial Effects against Various Foodborne Pathogens and Sensory Properties of Yogurt Supplemented with Panax ginseng Marc Extract.
- 2017-10-31
- Korean journal for food science of animal resources 37(5)
- - Su Jin Eom
  - Ji Eun Hwang
  - Kee-Tae Kim
  - Hyun-Dong Paik
- PubMed: 29147103
- DOI: 10.5851/kosfa.2017.37.5.787
1 Insight on
- Reduced Pathogen Growth
- Low evidence
Clostridium butyricum CGMCC0313.1 Protects against Autoimmune Diabetes by Modulating Intestinal Immune Homeostasis and Inducing Pancreatic Regulatory T Cells
- 2017-10-19
- RCT
- Frontiers in Immunology 8
- - Lingling Jia
  - Kai Shan
  - Li-Long Pan
  - Ninghan Feng
  - Zhuwu Lv
  - Yajun Sun
  - Jiahong Li
  - Chengfei Wu
  - Hao Zhang
  - Wei Chen
  - J. Diana
  - Jia Sun
  - Yong Q. Chen
- PubMed: 29097999
- DOI: 10.3389/fimmu.2017.01345
6 Insights on
- Low evidence
- Animal Study
Therapeutic potential of Bifidobacterium breve strain A1 for preventing cognitive impairment in Alzheimer's disease.
- 2017-10-18
- Scientific reports 7(1)
- - Yodai Kobayashi
  - Hirosuke Sugahara
  - Kousuke Shimada
  - Eri Mitsuyama
  - Tetsuya Kuhara
  - Akihito Yasuoka
  - Takashi Kondo
  - Keiko Abe
  - Jin-Zhong Xiao
- PubMed: 29044140
- DOI: 10.1038/s41598-017-13368-2
2 Insights on
- Improved Cognitive Function
- Reduced Neuroinflammation
- Low evidence
- Highly Cited
- Rigorous Journal
- Animal Study
Lactobacillus plantarum IS-10506 supplementation reduced SCORAD in children with atopic dermatitis.
- 2017-10-13
- RCT · n = 22
- Beneficial Microbes 8(5)
- - C. Prakoeswa
  - N. Herwanto
  - R. Prameswari
  - L. Astari
  - S. Sawitri
  - A. Hidayati
  - D. Indramaya
  - E. R. Kusumowidagdo
  - I. Surono
- PubMed: 29022387
- DOI: 10.3920/BM2017.0011
7 Insights on
- High evidence
The effect of probiotic Lactobacillus casei Shirota on knee osteoarthritis: a randomised double-blind, placebo-controlled clinical trial.
- 2017-10-13
- RCT · n = 537
- Beneficial microbes 8(5)
- - M Lei
  - C Guo
  - D Wang
  - C Zhang
  - L Hua
- PubMed: 28726510
- DOI: 10.3920/bm2016.0207
3 Insights on
- High evidence
- Large Human Trial
- Highly Cited
- Rigorous Journal
Flavanol-Rich Cocoa Powder Interacts with Lactobacillus rhamnossus LGG to Alter the Antibody Response to Infection with the Parasitic Nematode Ascaris suum
- 2017-10-12
- RCT
- Nutrients 9(10)
- - Saebyeol Jang
  - Sukla Lakshman
  - E. Beshah
  - Yue Xie
  - Aleksey Molokin
  - B. Vinyard
  - J. Urban
  - C. Davis
  - G. Solano-Aguilar
- PubMed: 29023393
- DOI: 10.3390/nu9101113
3 Insights on
- High evidence
Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients—A Systematic Review and Meta-Analysis
- 2017-10-12
- Meta-Analysis
- Antibiotics 6(4)
- - Sara Blaabjerg
  - D. Artzi
  - R. Aabenhus
- PubMed: 29023420
- DOI: 10.3390/antibiotics6040021
2 Insights on
- Reduced Antibiotic-Associated Diarrhea
- Increased Safety of Probiotic Use
- High evidence
- Highly Cited
The effect of Rosa (L. Rosa canina) on the incidence of urinary tract infection in the puerperium: A randomized placebo-controlled trial.
- 2017-10-11
- RCT · n = 400
- Phytotherapy research : PTR 32(1)
- - Mahdieh Seifi
  - Shamsi Abbasalizadeh
  - Sakineh Mohammad-Alizadeh-Charandabi
  - Laleh Khodaie
  - Mojgan Mirghafourvand
- PubMed: 29024081
- DOI: 10.1002/ptr.5950
2 Insights on
- Reduced Urinary Tract Infection
- Reduced Cystitis Incidence
- High evidence
- Large Human Trial
Lactobacillus plantarum BSGP201683 Isolated from Giant Panda Feces Attenuated Inflammation and Improved Gut Microflora in Mice Challenged with Enterotoxigenic Escherichia coli
- 2017-09-26
- Frontiers in Microbiology 8
- - Qian Liu
  - Xueqin Ni
  - Qiang Wang
  - Zhirong Peng
  - L. Niu
  - Hengsong Wang
  - Yi Zhou
  - Hao Sun
  - Kangcheng Pan
  - Bo Jing
  - Dong Zeng
- PubMed: 29018435
- DOI: 10.3389/fmicb.2017.01885
7 Insights on
- Low evidence
Lactobacillus paracasei feeding improves immune control of influenza infection in mice
- 2017-09-20
- Clinical Trial
- PLOS ONE 12(9)
- - Nouria Belkacem
  - Nicolas Serafini
  - R. Wheeler
  - M. Derrien
  - Lilia Boucinha
  - Aurélie Couesnon
  - N. Cerf‐Bensussan
  - Ivo Gomperts Boneca
  - J. D. Di Santo
  - Muhamed-Keir Taha
  - R. Bourdet-Sicard
- PubMed: 28931041
- DOI: 10.1371/journal.pone.0184976
4 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Effects of Supplementation with Beef or Whey Protein Versus Carbohydrate in Master Triathletes.
- 2017-09-14
- RCT · n = 8
- Journal of the American College of Nutrition 36(8)
- - Fernando Naclerio
  - Marco Seijo
  - Eneko Larumbe-Zabala
  - Nadia Ashrafi
  - Tatiana Christides
  - Bettina Karsten
  - Birthe V Nielsen
- PubMed: 28910233
- DOI: 10.1080/07315724.2017.1335248
4 Insights on
- High evidence
- Rigorous Journal
Effect of dragon fruit on glycemic control in prediabetes and type 2 diabetes: A systematic review and meta-analysis.
- 2017-09-08
- Meta-Analysis
- PloS one 12(9)
- - Nalinee Poolsup
  - Naeti Suksomboon
  - Naw Juna Paw
- PubMed: 28886195
- DOI: 10.1371/journal.pone.0184577
2 Insights on
- Improved Fasting Plasma Glucose
- Reduced Postprandial Glucose
- High evidence
Uva-ursi extract and ibuprofen as alternative treatments of adult female urinary tract infection (ATAFUTI): study protocol for a randomised controlled trial.
- 2017-09-08
- RCT · n = 328
- Trials 18(1)
- - Jeanne Trill
  - Catherine Simpson
  - Frances Webley
  - Mike Radford
  - Louise Stanton
  - Tom Maishman
  - Angeliki Galanopoulou
  - Andrew Flower
  - Caroline Eyles
  - Merlin Willcox
  - Alastair Hay
  - Gareth Griffiths
  - Paul Little
  - George Lewith
  - Michael Moore
- PubMed: 28886751
- DOI: 10.1186/s13063-017-2145-7
3 Insights on
- High evidence
- Large Human Trial
Lactic acid bacteria isolated from yak milk show probiotic potential
- 2017-09-06
- Applied Microbiology and Biotechnology 101(20)
- - M. Kaur
  - Harjodh Singh
  - Manoj Jangra
  - L. Kaur
  - Pallavi Jaswal
  - Chetna Dureja
  - H. Nandanwar
  - S. R. Chaudhuri
  - M. Raje
  - Sunita Mishra
  - A. K. Pinnaka
- PubMed: 28879447
- DOI: 10.1007/s00253-017-8473-4
4 Insights on
- Low evidence