3 Insights on

• Improved Intestinal Barrier Function
• Reduced Bacterial Translocation
• Reduced Inflammation

1 Insight on

• Reduced Nasal Symptoms

1 Insight on

• Improved Intestinal Function

15 Insights on

• Reduced Inflammatory Response
• Regulated Immune Response
• Enhanced Resistance to Infections
• Reduced Inflammation Levels
• Reduced Inflammation in the Female Reproductive Tract
• Non-toxicity to Cervicovaginal Epithelial Cells
• Reduced Urogenital Pathogen Activity
• Reduced Pathogen Colonization
• Non-Toxic Colonization
• Maintained Homeostasis
• Maintained Female Reproductive Tract Homeostasis
• Improved Colonization Resistance
• Improved Colonization Resistance to Pathogens
• Absence of Exogenous Toxicity
• Adhesion to Cervicovaginal Epithelial Cells

4 Insights on

• Reduced Small Intestinal Transit Time
• Increased Colonic Transepithelial Resistance
• Reduced Neurally Evoked Ion Secretion in the Colon
• Reduced Sensitivity to Tetrodotoxin (TTx) Inhibition in Short-circuit Current Response

4 Insights on

• Reduced Occurrence of Necrotizing Enterocolitis
• Reduced Risk of Necrotizing Enterocolitis
• Reduced NEC Incidence
• Altered Innate Immune Response

2 Insights on

• Reduced Coxsackievirus B3 Activity
• Reduced Coxsackievirus B3 Viral Load

4 Insights on

• Reduced Duration of Diarrhea
• Reduced Stool Frequency
• Reduced Risk of Diarrhea on Day 3
• Reduced Risk of Diarrhea on Day 4

4 Insights on

• Reduced Caries Risk
• Occurrence of Dental Caries
• Unchanged Caries Occurrence
• Increased Occurrence of Dental Caries

3 Insights on

• Improved Immune Response
• Reduced Inflammation
• Reduced Airway Hyperresponsiveness

1 Insight on

• Improved Gut Health

12 Insights on

• Improved Intestinal Microbiota
• Elevated Bifidobacterium Levels
• Increased Fecal Bifidobacteria
• Reduced Pseudomonas in Feces
• Improved Enteral Nutrition
• Reduced Pediatric Intensive Care Unit Stay
• Reduced Enterobacteriaceae Levels in Feces
• Increased Bifidobacterium Levels in Feces
• Reduced PICU Discharge Time
• Improved Enteral Nutrition Achievement Time
• Improved Enteral Nutrition Uptake
• Reduced Pseudomonas Levels

1 Insight on

• Reduced Growth of Streptococcus mutans

5 Insights on

• Reduced Severity of Necrotizing Enterocolitis
• Reduced Proinflammatory Signaling
• Reduced NEC Severity
• Reduced Mucosal Cytokine Response
• Improved Gross Morphology of Intestinal Tissue

1 Insight on

• Decreased Cancer-Testis Antigens

1 Insight on

• Improved Symptoms of Functional Bowel Disorders

2 Insights on

• Reduced IL-8 Production
• Reduced Inflammation

9 Insights on

• Reduced TNF-α Levels
• Reduced Plasma Lipopolysaccharide Levels
• Reduced Hepatic Steatosis
• Reduced IL-6 Levels
• Reduced Serum LPS Levels
• Reduced Serum IL-6 Levels
• Reduced Serum TNF-Alpha Level
• Reduced Serum TNF-α Levels
• Reduced Hepatic Neutral Lipids

2 Insights on

• Reduced Inflammation
• Reduced Proinflammatory Cytokine Secretion

5 Insights on

• Reduced Crying Time in Infants with Colic
• Reduced Nosocomial Diarrhea Incidence
• Improved Functional Constipation
• Improved Management of Acute Gastroenteritis
• Reduced Diarrhea Incidence in Day Care Centers

7 Insights on

• Reduced Pathogen Growth
• Improved Antimicrobial Ability
• Increased Bacterial Aggregation
• Preventive Effect Against Streptococcus agalactiae Infection
• Reduced Streptococcus agalactiae Growth
• Increased Aggregation of Streptococcus agalactiae
• No Reduction in Streptococcus agalactiae

6 Insights on

• Reduced Tumor Necrosis Factor Alpha
• Improved Height Percentile
• Decreased Peripheral CD3⁺ T Lymphocyte Count
• Reduced Bacteroides Fragilis Group Numbers
• Reduced Secretory IgA Content in Faeces
• Reduced Secretory Immunoglobulin A in Stools

3 Insights on

• Improved Skin Symptoms
• Improved Skin Condition
• Prevention or Treatment of Allergic Skin Disorders

5 Insights on

• Reduced Pro-Inflammatory Cytokines
• Reduced Inflammatory Response
• Reduced Phospho-p65 Translocation
• Reduced Proinflammatory Signaling
• Reduced Intestinal Inflammation

1 Insight on

• Improved Diversity of Gut Microbiota

4 Insights on

• Reduced Body Weight
• Reduced Interleukin-6 Production
• Reduced Virus Titer
• Reduced Total Cells in Bronchoalveolar Lavage Fluid

6 Insights on

• Improved Intestinal Barrier Function
• Reduced Diarrhea Incidence
• Improved Intestinal Morphology
• Improved Growth Performance
• Improved Weight Gain
• Unchanged Intestinal Morphology

12 Insights on

• Reduced Duration of Diarrhea
• Reduced Diarrhea Incidence
• Reduced Diarrhea Frequency
• Reduced Antibiotic Usage
• Reduced Frequency of Upper Respiratory Tract Infections
• Reduced School Absenteeism Due to Infectious Diseases
• Reduced Doctor Visits
• Reduced Healthcare Costs
• Reduced Duration of Respiratory Tract Infections
• Reduced Parental Absenteeism from Work
• Reduced Community Healthcare Costs
• Reduced Respiratory Tract Infection Episodes

1 Insight on

• Enhanced Antimicrobial Resistance

3 Insights on

• Reduced DNA Damage
• Reduced Beta-Glucuronidase Activity
• Reduced N-acetyl-β-glucosaminidase Activity