2 Insights on

• Increased Fecal Propionic Acid Levels
• Increased Visceral Fat Mass

21 Insights on

• Improved Bowel Movement Frequency
• Increased Bifidobacteria Levels
• Successful Gastrointestinal Tract Colonization
• Relieved Constipation
• Increased Intestinal Bifidobacteria Levels
• Increased Fecal Bifidobacteria
• Increased Levels of Bifidobacteria
• Increased Probiotic B. lactis Levels
• No Change in Endogenous Bifidobacteria Levels
• Increased Bifidobacteria Growth
• Increased Intestinal Bifidobacterium Levels
• Increased Intestinal Bifidobacteria Population
• Increased Defecation Frequency
• Improved Constipation
• Increased Bacterial Proliferation
• Preserved Endogenous Bifidobacteria Composition
• Increased Bifidobacteria Levels in Intestine
• Increased Proliferation of Administered Bifidobacteria
• Increased Bifidobacterium lactis GCL2505 Intestinal Proliferation
• No Change in Endogenous Bifidobacteria Species
• Increased Bifidobacterium lactis Proliferation in the Intestine

2 Insights on

• Increased Anticancer Treatment Adherence
• Reduced Mucositis

3 Insights on

• Reduced Candida albicans Growth
• Protection Against Oral Candidiasis
• Reduced Severity of Oral Candidiasis

14 Insights on

• Reduced Mortality Rate
• Improved Macroscopic Colonic Damage
• Reduced Beta-Glucuronidase Activity
• Increased IL-10 Production
• Reduced Myeloperoxidase Activity
• Reduced Colonic Oxidative Damage
• Faster Recovery of Body Weight
• Reduced Microbial Translocation to the Liver
• Reduced Interferon-Gamma Production
• Reduced Microbial Translocation
• Accelerated Weight Loss Recovery
• Reduced Colonic Microscopic Damage
• Reduced Gut IFN-γ Production
• Increased Interleukin-10 Production in the Gut

7 Insights on

• Increased Body Weight
• Reduced Gastrointestinal Infections
• Reduced Incidence of Gastrointestinal Adverse Events
• Improved Feeding Tolerance
• No Significant Difference in Weight Gain
• Improved Formula Tolerance
• Reduced Incidence of Gastrointestinal Tract Infection Symptoms

1 Insight on

• Reduced Bacteroides Fragilis Group Numbers

5 Insights on

• Reduced Upper Respiratory Infections
• Reduced Incidence of Upper Respiratory Tract Infections
• Reduced Gastrointestinal Infections
• Reduced Total Infections
• Reduced Incidence of Gastrointestinal Adverse Events

5 Insights on

• Reduced Genotoxicity
• No Adverse Effects
• No Observed Toxicity
• No Cytochrome P450 Induction
• No CYP1A2 or CYP3A4 Interaction

9 Insights on

• Reduced Colitis Symptoms
• Improved Epithelial Barrier Function
• Reduced Proinflammatory Cytokine Production
• Increased Production of Anti-inflammatory Cytokine IL-10
• Increased Anti-inflammatory Cytokines
• Reduced Proinflammatory Cytokine Secretion
• Increased IL-10 Production
• Increased CCL-20 Levels
• Improved Intestinal Epithelial Barrier

4 Insights on

• Reduced Inflammatory Response
• Reduced Proinflammatory Signaling
• Improved Homeostasis
• Enhanced Negative Regulation of TLR Activity

1 Insight on

• Enhanced Intestinal Epithelial Cell Adhesion

5 Insights on

• Reduced Diarrhea Rate
• Reduced Cholesterol Levels
• Improved Irritable Bowel Syndrome Symptoms
• Reduced Antibiotic-Associated Diarrhoea in Children
• Improved Host Immunity

1 Insight on

• Increased Body Weight Gain

4 Insights on

• Increased Body Weight
• Increased Salivary sIgA Levels
• Improved Humoral Immune Response
• Increased Weight in Normal Weight Children

5 Insights on

• Enhanced Natural Killer Cell Activity
• Reduced Influenza Virus Titer
• Extended Survival Periods
• Increased Anti-Influenza Virus Antibodies
• Prolonged Survival Periods with Antiphospholipid Syndrome

6 Insights on

• Activated Immune Response
• Enhanced Phenotypic Maturation of Dendritic Cells
• Increased IL-10 Production
• Improved Diversification of B-Cell Populations
• Diversified B-cell Populations in the Lamina Propria
• Diversified B-Cell Populations in the Colon

1 Insight on

• Improved Gut Health

1 Insight on

• Reduced S. aureus Cell Count In Vivo

10 Insights on

• Improved Vaginal Microbiota Balance
• Increased Abundance of Lactobacillus Crispatus
• Improved Vaginal Colonization with Probiotics
• Reduced Concentration of Bacterial Vaginosis-Associated Bacteria
• Reduced Atopobium spp. Concentration
• Unchanged Gardnerella vaginalis Concentration
• Reduced Colonization with Probiotic Lactobacillus crispatus
• Reduced BV-Associated Bacteria
• Reduced Odds of Probiotic Lactobacilli Successful Colonization
• Reduced Colonization with Probiotic Lactobacilli

9 Insights on

• Improved Intestinal Barrier Function
• Improved Survival Rate
• Reduced Colitis Severity
• Relieved Intestinal Impairments
• Reduced Intestinal Inflammation
• Reduced Intestinal Tissue Injury
• Modulated Cytokine Production
• Improved Survival
• Improved Colitis Survival

2 Insights on

• Increased Intestinal Epithelial Cell Adhesion
• Enhanced IL-12 Production

2 Insights on

• Increased Interferon-Gamma Levels
• Increased Antioxidant Capacity

4 Insights on

• Increased Serum Lysozyme Activity
• Improved Survival Rate
• Improved Serum Acid Phosphatase Activity
• Improved Post-Challenge Survival

1 Insight on

• No Adverse Health Effects

19 Insights on

• Increased Fecal Lactobacilli
• Reduced Fecal Enterococci Levels
• Increased Gut Bifidobacteria
• Reduced Potential Pathogenic Bacteria
• Increased Fecal Bifidobacteria Levels
• Reduced Enterococci Counts
• Increased Fecal Bifidobacteria
• Increased Beneficial Gut Bacteria
• Increased Beneficial Bifidobacteria
• Increased Probiotic B. lactis Levels
• Increased Bifidobacteria Count
• Increased Fecal Lactobacilli Viability
• Increased Fecal Lactobacillus Count
• Stable Plasma Cholesterol Levels
• Increased Specific Probiotic Strains
• Increased Fecal Probiotic Strains
• Reduced Enterococci Levels
• Increased Beneficial Bacterial Counts
• Reduced Fecal Enterococci

3 Insights on

• Improved Gastrointestinal Survival
• Improved Survival of Probiotic Bacteria
• Rapid Galactooligosaccharide Degradation During Gastrointestinal Transit

2 Insights on

• Reduced Bloating
• Improved Bloating Symptoms

1 Insight on

• No Clinically Significant Hematological Changes

2 Insights on

• Enhanced Innate Immune Response
• Increased Paneth Cell Number in Intestinal Crypts