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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Meta-analysis evaluating the impact of chili-pepper intake on all-cause and cardiovascular mortality: A systematic review.
- 2021-10
- Review
- Annals of medicine and surgery (2012) 70
- - Naser Yamani
  - Adeena Musheer
  - Priyanka Gosain
  - Saba Sarfraz
  - Humera Qamar
  - Muhammad Maaz Waseem
  - Muhammad Sameer Arshad
  - Talal Almas
  - Vincent Figueredo
- PubMed: 34603712
- DOI: 10.1016/j.amsu.2021.102774
4 Insights on
- Low evidence
Probiotic lactobacilli in formulas and hygiene products for the health of the urogenital tract.
- 2021-10
- Review
- Pharmacology research & perspectives 9(5)
- - María Elena Fátima Nader-Macías
  - Priscilla Romina De Gregorio
  - Jessica Alejandra Silva
- PubMed: 34609059
- DOI: 10.1002/prp2.787
4 Insights on
- Low evidence
Lactobacillus rhamnosus postbiotic-induced immunomodulation as safer alternative to the use of live bacteria.
- 2021-10
- Cytokine 146
- - S. Salva
  - I. Tiscornia
  - Florencia Gutiérrez
  - S. Alvarez
  - M. Bollati-Fogolín
- PubMed: 34252871
- DOI: 10.1016/j.cyto.2021.155631
5 Insights on
- Low evidence
Probiotic, Lactobacillus pentosus BD6 boost the growth and health status of white shrimp, Litopenaeus vannamei via oral administration.
- 2021-10
- Fish & Shellfish Immunology 117
- - Shieh-Tsung Chiu
  - T. Chu
  - Tohap Simangunsong
  - Rolissa Ballantyne
  - Chiu-Shia Chiu
  - Chun‐Hung Liu
- PubMed: 34343542
- DOI: 10.1016/j.fsi.2021.07.024
4 Insights on
- Low evidence
Inorganic polyphosphate from the immunobiotic Lactobacillus rhamnosus CRL1505 prevents inflammatory response in the respiratory tract
- 2021-10
- Clinical Trial
- Saudi Journal of Biological Sciences 28(10)
- - M. A. Correa Deza
  - A. Rodríguez de Olmos
  - N. Suárez
  - G. Font de Valdez
  - S. Salva
  - C. L. Gerez
- PubMed: 34588880
- DOI: 10.1016/j.sjbs.2021.06.010
3 Insights on
- Low evidence
- Animal Study
Review of Clinical Effects and Presumed Mechanism of Action of the French Oak Wood Extract Robuvit.
- 2021-09
- Review · n = 1,172
- Journal of medicinal food 24(9)
- - Franziska Weichmann
  - Fabrice Avaltroni
  - Carolina Burki
- PubMed: 33512270
- DOI: 10.1089/jmf.2020.0165
2 Insights on
- Improved Liver Function
- Improved Renal Function
- High evidence
Complete genome sequence of Lactobacillus amylovorus 1394N20, a potential probiotic strain, isolated from a Hanwoo calf
- 2021-09
- Journal of Animal Science and Technology 63(5)
- - Young Joon Oh
  - Joon-Yong Kim
  - Jieun Lee
  - S. Lim
  - Dohyeon Yu
  - Yeonsu Oh
  - Jinho Park
  - Hak-Jong Choi
- PubMed: 34796359
- DOI: 10.5187/jast.2021.e100
2 Insights on
- Improved Gut Health
- Improved Digestibility
- Low evidence
- Rigorous Journal
Mastiha has efficacy in immune-mediated inflammatory diseases through a microRNA-155 Th17 dependent action.
- 2021-09
- RCT
- Pharmacological research 171
- - Charalampia Amerikanou
  - Efstathia Papada
  - Aristea Gioxari
  - Ilias Smyrnioudis
  - Stamatia-Angeliki Kleftaki
  - Evdokia Valsamidou
  - Victoria Bruns
  - Rajarshi Banerjee
  - Maria Giovanna Trivella
  - Natasa Milic
  - Milica Medić-Stojanoska
  - Amalia Gastaldelli
  - Aimo Kannt
  - George V Dedoussis
  - Andriana C Kaliora
- PubMed: 34224858
- DOI: 10.1016/j.phrs.2021.105753
2 Insights on
- Reduced Interleukin-6 Levels
- Reduced miR-155 Level
- High evidence
A randomized, double blind, parallel, placebo‐controlled study to investigate the efficacy of Lactobacillus paracasei N1115 in gut development of young children
- 2021-09
- RCT · n = 58
- Food Science & Nutrition 9(11)
- - Shijie Wang
  - Yiping Xun
  - Grace J Ahern
  - Lili Feng
  - Dong Zhang
  - Yuling Xue
  - R. Ross
  - Andrea M Doolan
  - C. Stanton
  - Hong Zhu
- PubMed: 34760234
- DOI: 10.1002/fsn3.2533
2 Insights on
- Increased Lactobacilli Levels
- Stable Bowel Function
- High evidence
N-acetyl cysteine versus standard of care for non-acetaminophen induced acute liver injury: a systematic review and meta-analysis.
- 2021-09
- Meta-Analysis · n = 11
- Annals of hepatology 24
- - Dhan Bahadur Shrestha
  - Pravash Budhathoki
  - Yub Raj Sedhai
  - Anurag Adhikari
  - Ayusha Poudel
  - Barun Aryal
  - Ramkaji Baniya
- PubMed: 33722689
- DOI: 10.1016/j.aohep.2021.100340
3 Insights on
- High evidence
The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial.
- 2021-09
- RCT · n = 271
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 141
- - Ali Shahriari
  - Elham Karimi
  - Mohammadali Shahriari
  - Neda Aslani
  - Maryam Khooshideh
  - Arman Arab
- PubMed: 34328109
- DOI: 10.1016/j.biopha.2021.111915
3 Insights on
- High evidence
- Large Human Trial
Effects of Lactobacillus acidophilus on the growth performance, immune response, and intestinal barrier function of broiler chickens challenged with Escherichia coli O157
- 2021-09
- RCT · n = 360
- Poultry Science 100(9)
- - Zhengke Wu
  - Kexin Yang
  - A. Zhang
  - Wenhuan Chang
  - A. Zheng
  - Zhi-Min Chen
  - Huiyi Cai
  - Guohua Liu
- PubMed: 34280647
- DOI: 10.1016/j.psj.2021.101323
14 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Effects of Bacillus subtilis and Bacillus licheniformis on growth performance, immunity, short chain fatty acid production, antioxidant capacity, and cecal microflora in broilers
- 2021-09
- RCT · n = 360
- Poultry Science 100(9)
- - Yinglei Xu
  - Yang Yu
  - Yuanyuan Shen
  - Qing Li
  - J. Lan
  - Yan-ping Wu
  - Ruiqiang Zhang
  - Guantian Cao
  - Caimei Yang
- PubMed: 34358955
- DOI: 10.1016/j.psj.2021.101358
6 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Acute effects of hemp protein consumption on glycemic and satiety control: results of 2 randomized crossover trials.
- 2021-08
- RCT
- Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 46(8)
- - Rebecca C Mollard
  - Alie Johnston
  - Alejandra Serrano Leon
  - Haizhou Wang
  - Peter J Jones
  - Dylan S MacKay
- PubMed: 33493023
- DOI: 10.1139/apnm-2020-0907
2 Insights on
- Improved Insulin Levels
- Reduced Blood Glucose Levels
- High evidence
Lactobacillus crispatus promotes invasion of the HTR-8/SVneo trophoblast cell line.
- 2021-08
- Placenta 111
- - Tomoaki Yoshida
  - Kazuhide Takada
  - Shihoko Komine-Aizawa
  - Y. Kamei
  - O. Ishihara
  - S. Hayakawa
- PubMed: 34175522
- DOI: 10.1016/j.placenta.2021.06.006
1 Insight on
- Enhanced Trophoblast Invasion
- Low evidence
Lactobacillus johnsonii activates porcine monocyte derived dendritic cells maturation to modulate Th cellular immune response.
- 2021-08
- Cytokine 144
- - D. Zheng
  - Zhaorui Wang
  - Ling Sui
  - Yigang Xu
  - Li Wang
  - X. Qiao
  - W. Cui
  - Yan-ping Jiang
  - Han Zhou
  - Lijie Tang
  - Yi-jing Li
- PubMed: 34029942
- DOI: 10.1016/j.cyto.2021.155581
4 Insights on
- Low evidence
Spore-forming Bacillus coagulans SNZ 1969 improved intestinal motility and constipation perception mediated by microbial alterations in healthy adults with mild intermittent constipation: A randomized controlled trial.
- 2021-08
- RCT · n = 80
- Food Research International 146
- - Seunghee Kang
  - M. Park
  - I. Brooks
  - Jaekyung Lee
  - S. Kim
  - Ji Yeon Kim
  - Bumjo Oh
  - Ji Won Kim
  - O. Kwon
- PubMed: 34119240
- DOI: 10.1016/j.foodres.2021.110428
10 Insights on
- High evidence
Inhibitory effects of Lactobacillus brevis KU15153 against Streptococcus mutans KCTC 5316 causing dental caries.
- 2021-08
- Microbial Pathogenesis 157
- - H. Jang
  - Jong Ha Kim
  - N. Lee
  - H. Paik
- PubMed: 34022360
- DOI: 10.1016/j.micpath.2021.104938
2 Insights on
- Reduced Mutans Streptococci Colonization
- Reduced Cariogenic Bacteria
- Low evidence
Enhancement the antibacterial properties of kefir by adding Lactobacillus fermentum grx08.
- 2021-08
- Journal of Food Protection 84(8)
- - Tian Lv
  - Xueting Huang
  - Chenchen Zhang
  - Dawei Chen
  - R. Gu
  - Yunchao Wa
  - Kuiyao Peng
  - Lina Zong
  - Xia Chen
- PubMed: 33902109
- DOI: 10.4315/JFP-21-113
2 Insights on
- Improved Antibacterial Activity
- Reduced Acidity
- Low evidence
Heat-sterilized Bifidobacterium breve prevents depression-like behavior and interleukin-1β expression in mice exposed to chronic social defeat stress
- 2021-08
- Clinical Trial
- Brain, Behavior, and Immunity 96
- - Aika Kosuge
  - Kazuo Kunisawa
  - S. Arai
  - Yumika Sugawara
  - Katsuki Shinohara
  - Tsubasa Iida
  - Bolati Wulaer
  - T. Kawai
  - H. Fujigaki
  - Yasuko Yamamoto
  - Kuniaki Saito
  - T. Nabeshima
  - A. Mouri
- PubMed: 34062230
- DOI: 10.1016/j.bbi.2021.05.028
2 Insights on
- Improved Gut Microbiota Composition
- Reduced Depressive Behavior
- Low evidence
- Rigorous Journal
- Animal Study
Biotransformation of the Brazilian Caatinga fruit-derived phenolics by Lactobacillus acidophilus La-5 and Lacticaseibacillus casei 01 impacts bioaccessibility and antioxidant activity.
- 2021-08
- Food Research International 146
- - Bianca Beatriz Torres de Assis
  - T. C. Pimentel
  - A. M. Dantas
  - Marcos dos Santos Lima
  - Graciele da Silva Campelo Borges
  - M. Magnani
- PubMed: 34119243
- DOI: 10.1016/j.foodres.2021.110435
2 Insights on
- Increased Antioxidant Activity
- Increased Bioavailability of Phenolics
- Low evidence
Effect of kefir beverage consumption on glycemic control: A systematic review and meta-analysis of randomized controlled clinical trials.
- 2021-08
- Meta-Analysis
- Complementary Therapies in Clinical Practice 44
- - A. Salari
  - Sara Ghodrat
  - Alireza Gheflati
  - L. Jarahi
  - M. Hashemi
  - A. Afshari
- PubMed: 34280689
- DOI: 10.1016/j.ctcp.2021.101443
5 Insights on
- High evidence
Exopolysaccharides produced by Pediococcus acidilactici MT41-11 isolated from camel milk: Structural characteristics and bioactive properties.
- 2021-08
- International Journal of Biological Macromolecules 185
- - Ying Bai
  - Baolong Luo
  - Yan Zhang
  - Xu Li
  - Zhen Wang
  - Yuqing Shan
  - Min Lu
  - F. Tian
  - Yongqing Ni
- PubMed: 34175337
- DOI: 10.1016/j.ijbiomac.2021.06.152
1 Insight on
- Increased Antioxidant Activity
- Low evidence
Lacticaseibacillus rhamnosus GR-1, a.k.a. Lactobacillus rhamnosus GR-1: Past and Future Perspectives.
- 2021-08
- Review
- Trends in Microbiology 29(8)
- - M. Petrova
  - G. Reid
  - Jessica A. ter Haar
- PubMed: 33865678
- DOI: 10.1016/j.tim.2021.03.010
8 Insights on
- Low evidence
Bacillus amyloliquefaciens B10 can alleviate aflatoxin B1-induced kidney oxidative stress and apoptosis in mice.
- 2021-07
- RCT · n = 56
- Ecotoxicology and Environmental Safety 218
- - Yeqi Zhao
  - Tiancheng Wang
  - Peng Li
  - Jia Chen
  - E. Nepovimova
  - M. Long
  - Wenda Wu
  - K. Kuča
- PubMed: 33933810
- DOI: 10.1016/j.ecoenv.2021.112286
3 Insights on
- Low evidence
- Animal Study
Meta-analysis of effects of inoculation with Lactobacillus buchneri, with or without other bacteria, on silage fermentation, aerobic stability, and performance of dairy cows.
- 2021-07
- Meta-Analysis
- Journal of Dairy Science 104(7)
- - K. Arriola
  - A. Oliveira
  - Yun Jiang
  - Donghyeon Kim
  - H. M. Silva
  - Sam-Churl Kim
  - F. Amaro
  - I. Ogunade
  - H. Sultana
  - A. P. Pech Cervantes
  - L. Ferraretto
  - D. Vyas
  - A. Adesogan
- PubMed: 33814134
- DOI: 10.3168/jds.2020-19647
6 Insights on
- High evidence
- Rigorous Journal
Supplementation with Bifidobacterium breve BR03 and B632 strains improved insulin sensitivity in children and adolescents with obesity in a cross-over, randomized double-blind placebo-controlled trial.
- 2021-07
- RCT · n = 101
- Clinical Nutrition 40(7)
- - Arianna Solito
  - Nicole Bozzi Cionci
  - M. Calgaro
  - M. Caputo
  - L. Vannini
  - Iderina Hasballa
  - Francesca Archero
  - E. Giglione
  - R. Ricotti
  - G. Walker
  - A. Petri
  - Emanuela Agosti
  - G. Bellomo
  - G. Aimaretti
  - G. Bona
  - S. Bellone
  - A. Amoruso
  - M. Pane
  - D. Di Gioia
  - N. Vitulo
  - F. Prodam
- PubMed: 34229263
- DOI: 10.1016/j.clnu.2021.06.002
6 Insights on
- High evidence
Bifidobacteria-mediated immune system imprinting early in life
- 2021-07
- Cell 184(15)
- - B. Henrick
  - L. Rodriguez
  - T. Lakshmikanth
  - Christian Pou
  - E. Henckel
  - E. Henckel
  - E. Henckel
  - Axel Olin
  - Jun Wang
  - J. Mikeš
  - Ziyang Tan
  - Yang Chen
  - Amy M. Ehrlich
  - A. Bernhardsson
  - C. Mugabo
  - Ylva Ambrosiani
  - Anna Gustafsson
  - Anna Gustafsson
  - Stephanie Chew
  - H. Brown
  - Johann Prambs
  - Kajsa Bohlin
  - Kajsa Bohlin
  - Ryan D. Mitchell
  - M. Underwood
  - J. Smilowitz
  - J. German
  - S. Frese
  - P. Brodin
  - P. Brodin
- PubMed: 34143954
- DOI: 10.1016/j.cell.2021.05.030
3 Insights on
- High evidence
- Highly Cited
Safety assessment of Streptococcus salivarius DB-B5 as a probiotic candidate for oral health.
- 2021-07
- Food and Chemical Toxicology 153
- - Xuyao Li
  - F. R. Fields
  - M. Ho
  - Allyson Marshall-Hudson
  - R. Gross
  - Michael E Casser
  - M. Naito
- PubMed: 34004226
- DOI: 10.1016/j.fct.2021.112277
1 Insight on
- Improved Safe Consumption Practices
- Low evidence
Prebiotics and alternative poultry production.
- 2021-07
- Review
- Poultry science 100(7)
- - Steven C Ricke
- PubMed: 34102481
- DOI: 10.1016/j.psj.2021.101174
3 Insights on
- Low evidence
- Animal Study