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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Bifidobacterium adolescentis CGMCC 15058 alleviates liver injury, enhances the intestinal barrier and modifies the gut microbiota in d-galactosamine-treated rats
- 2018-10-22
- Clinical Trial
- Applied Microbiology and Biotechnology 103(1)
- - Yating Li
  - L. Lv
  - Jianzhong Ye
  - D. Fang
  - D. Shi
  - Wen-rui Wu
  - Qing Wang
  - Jingjing Wu
  - Liya Yang
  - Xiaoyuan Bian
  - Xianwan Jiang
  - Huiyong Jiang
  - Ren Yan
  - Conggao Peng
  - Lanjuan Li
- PubMed: 30345482
- DOI: 10.1007/s00253-018-9454-y
7 Insights on
- Low evidence
- Animal Study
Growth in Hyper-Concentrated Sweet Whey Triggers Multi Stress Tolerance and Spray Drying Survival in Lactobacillus casei BL23: From the Molecular Basis to New Perspectives for Sustainable Probiotic Production
- 2018-10-22
- Frontiers in Microbiology 9
- - Song Huang
  - Floriane Gaucher
  - C. Cauty
  - J. Jardin
  - Y. Le Loir
  - R. Jeantet
  - X. Chen
  - G. Jan
- PubMed: 30405593
- DOI: 10.3389/fmicb.2018.02548
7 Insights on
- Low evidence
Effect of early probiotic supplementation on childhood cognition, behaviour and mood a randomised, placebo-controlled trial.
- 2018-10-22
- RCT · n = 474
- Acta paediatrica (Oslo, Norway : 1992) 107(12)
- - R F Slykerman
  - J Kang
  - N Van Zyl
  - C Barthow
  - K Wickens
  - T Stanley
  - C Coomarasamy
  - G Purdie
  - R Murphy
  - J Crane
  - E A Mitchell
- PubMed: 30246890
- DOI: 10.1111/apa.14590
5 Insights on
- High evidence
- Large Human Trial
What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing Research.
- 2018-10-16
- Review
- Gastroenterology research and practice 2018
- - Han-Yi Song
  - Long Zhou
  - Dong-Yan Liu
  - Xin-Jie Yao
  - Yan Li
- PubMed: 30410538
- DOI: 10.1155/2018/9379480
4 Insights on
- Low evidence
Lactobacillus fermentum strains from human breast milk with probiotic properties and cholesterol-lowering effects
- 2018-10-16
- Food Science and Biotechnology 28(2)
- - M. Asan-Ozusaglam
  - A. Gunyakti
- PubMed: 30956862
- DOI: 10.1007/s10068-018-0494-y
1 Insight on
- Improved Auto-Aggregation Capability
- Low evidence
Lactobacillus brevis 23017 Relieves Mercury Toxicity in the Colon by Modulation of Oxidative Stress and Inflammation Through the Interplay of MAPK and NF-κB Signaling Cascades
- 2018-10-12
- Clinical Trial
- Frontiers in Microbiology 9
- - Xinpeng Jiang
  - S. Gu
  - Di Liu
  - Lili Zhao
  - S. Xia
  - Xinmiao He
  - Hongyan Chen
  - Junwei Ge
- PubMed: 30369917
- DOI: 10.3389/fmicb.2018.02425
7 Insights on
- Low evidence
- Animal Study
Lactobacillus plantarum 299v Supplementation Improves Vascular Endothelial Function and Reduces Inflammatory Biomarkers in Men With Stable Coronary Artery Disease
- 2018-10-12
- Clinical Trial · n = 20
- Circulation Research 123(9)
- - Mobin Malik
  - T. Suboc
  - Sudhi Tyagi
  - N. Salzman
  - Jingli Wang
  - Rong Ying
  - Michael J. Tanner
  - Mamatha Kakarla
  - J. Baker
  - Michael E. Widlansky
- PubMed: 30355158
- DOI: 10.1161/CIRCRESAHA.118.313565
4 Insights on
- High evidence
- Highly Cited
- Rigorous Journal
The Effects of Probiotic Formulation Pretreatment (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) on a Lipopolysaccharide Rat Model
- 2018-10-11
- RCT · n = 4
- Journal of the American College of Nutrition 38(3)
- - Ghazaleh Mohammadi
  - L. Dargahi
  - A. Peymani
  - Y. Mirzanejad
  - S. Alizadeh
  - T. Naserpour
  - Marjan Nassiri-Asl
- PubMed: 30307792
- DOI: 10.1080/07315724.2018.1487346
3 Insights on
- Low evidence
- Animal Study
Whole-Genome Sequence of Lactobacillus salivarius DJ-sa-01, Isolated from Chicken Small Intestine.
- 2018-10-11
- Microbiology resource announcements 7(14)
- - Dongjun Kim
  - Mun-Ju Cho
  - Seungchan Cho
  - Yongjun Lee
  - Sung June Byun
  - Sukchan Lee
- PubMed: 30533717
- DOI: 10.1128/mra.00987-18
3 Insights on
- Low evidence
l-selenomethionine supplementation in children and adolescents with autoimmune thyroiditis: A randomized double-blind placebo-controlled clinical trial.
- 2018-10-10
- RCT
- Journal of clinical pharmacy and therapeutics 44(1)
- - Ioannis Kyrgios
  - Styliani Giza
  - Eleni P Kotanidou
  - Angeliki Kleisarchaki
  - Vasiliki Rengina Tsinopoulou
  - Vasiliki Rengina Tsinopoulou
  - Anastasia Papadopoulou
  - Anthi-Marina Markantonatou
  - Eleni Kanellidou
  - Anastasia Giannakou
  - Assimina Galli-Tsinopoulou
- PubMed: 30306604
- DOI: 10.1111/jcpt.12765
3 Insights on
- High evidence
Effects of Probiotic (Bifidobacterium longum 35624) Supplementation on Exercise Performance, Immune Modulation, and Cognitive Outlook in Division I Female Swimmers
- 2018-10-10
- RCT · n = 17
- Sports 6(4)
- - Aaron F Carbuhn
  - Shelby M Reynolds
  - C. W. Campbell
  - L. Bradford
  - J. Deckert
  - A. Kreutzer
  - A. Fry
- PubMed: 30308984
- DOI: 10.3390/sports6040116
1 Insight on
- Improved Cognitive Function
- High evidence
Bifidobacteria attenuate the development of metabolic disorders, with inter- and intra-species differences.
- 2018-10-09
- Clinical Trial
- Food & Function 9(6)
- - G. Zhu
  - Fangli Ma
  - Gang Wang
  - Yuanyuan Wang
  - Jianxin Zhao
  - Hao Zhang
  - Wei Chen
- PubMed: 29892745
- DOI: 10.1039/c8fo00100f
5 Insights on
- Low evidence
- Animal Study
Protective Effect of Pediococcus pentosaceus LI05 Against Clostridium difficile Infection in a Mouse Model
- 2018-10-09
- Clinical Trial
- Frontiers in Microbiology 9
- - Qiaomai Xu
  - Silan Gu
  - Yunbo Chen
  - Jiazheng Quan
  - L. Lv
  - Da-Zhi Chen
  - B. Zheng
  - Lichen Xu
  - Lanjuan Li
- PubMed: 30356740
- DOI: 10.3389/fmicb.2018.02396
6 Insights on
- Low evidence
- Animal Study
Common Cervicovaginal Microbial Supernatants Alter Cervical Epithelial Function: Mechanisms by Which Lactobacillus crispatus Contributes to Cervical Health
- 2018-10-08
- Frontiers in Microbiology 9
- - L. Anton
  - Luz-Jeannette Sierra
  - A. Devine
  - Guillermo O. Barila
  - Laura M. Heiser
  - Amy G. Brown
  - M. Elovitz
- PubMed: 30349508
- DOI: 10.3389/fmicb.2018.02181
2 Insights on
- Protection of Cervical Epithelial Barrier
- Reduced Cervical Inflammation
- Low evidence
- Highly Cited
Postnatal Administration of Lactobacillus rhamnosus HN001 Ameliorates Perinatal Broad‐Spectrum Antibiotic‐Induced Reduction in Myelopoiesis and T Cell Activation in Mouse Pups
- 2018-10-04
- Clinical Trial
- Molecular Nutrition & Food Research 62(22)
- - E. Fuglsang
  - L. Krych
  - M. Lundsager
  - D. Nielsen
  - H. Frøkiaer
- PubMed: 30211987
- DOI: 10.1002/mnfr.201800510
3 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Hibiscus extract, vegetable proteases and Commiphora myrrha are useful to prevent symptomatic UTI episode in patients affected by recurrent uncomplicated urinary tract infections.
- 2018-09-30
- Clinical Trial · n = 25
- Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 90(3)
- - Tommaso Cai
  - Daniele Tiscione
  - Andrea Cocci
  - Marco Puglisi
  - Gianmartin Cito
  - Gianni Malossini
  - Alessandro Palmieri
- PubMed: 30362679
- DOI: 10.4081/aiua.2018.3.203
3 Insights on
- Moderate evidence
Antiviral potentials of Lactobacillus plantarum, Lactobacillus amylovorus, and Enterococcus hirae against selected Enterovirus.
- 2018-09-29
- Folia microbiologica 64(2)
- - Abidemi Anota Sunmola
  - Omonike O Ogbole
  - Temitope O C Faleye
  - Adewale Adetoye
  - Johnson A Adeniji
  - Funmilola A Ayeni
- PubMed: 30267215
- DOI: 10.1007/s12223-018-0648-6
2 Insights on
- Reduced Enterovirus Replication
- Reduced Enterovirus Infectivity
- Low evidence
Lactobacillus johnsonii CJLJ103 Attenuates Scopolamine-Induced Memory Impairment in Mice by Increasing BDNF Expression and Inhibiting NF-κB Activation.
- 2018-09-28
- Clinical Trial
- Journal of Microbiology and Biotechnology 28(9)
- - Hae-Ji Lee
  - Su-Min Lim
  - Dong-Hyun Kim
- PubMed: 30111074
- DOI: 10.4014/jmb.1805.05025
2 Insights on
- Enhanced Brain-Derived Neurotrophic Factor Levels
- Improved Memory Function
- Low evidence
- Animal Study
Effects of Lactococcus lactis subsp. lactis I2 with β-Glucooligosaccharides on Growth, Innate Immunity and Streptococcosis Resistance in Olive Flounder (Paralichthys olivaceus).
- 2018-09-28
- RCT · n = 2
- Journal of Microbiology and Biotechnology 28(9)
- - M. T. Hasan
  - W. Jang
  - Jin Yeong Tak
  - Bong-Joo Lee
  - K. Kim
  - Sang-woo Hur
  - Hyonsob Han
  - Bo-Seong Kim
  - Do-Huh Min
  - Shin-Kwon Kim
  - I. Kong
- PubMed: 30176713
- DOI: 10.4014/jmb.1805.05011
13 Insights on
- Low evidence
- Animal Study
Effects of daily consumption of the probiotic Bifidobacterium animalis subsp. lactis CECT 8145 on anthropometric adiposity biomarkers in abdominally obese subjects: a randomized controlled trial
- 2018-09-27
- RCT · n = 125
- International Journal of Obesity 43(9)
- - A. Pedret
  - R. Valls
  - L. Calderón-Pérez
  - E. Llauradó
  - J. Companys
  - L. Pla-Pagà
  - A. Moragas
  - F. Martín-Luján
  - Y. Ortega
  - M. Giralt
  - A. Caimari
  - E. Chenoll
  - S. Genovés
  - P. Martorell
  - F. Codoñer
  - D. Ramón
  - L. Arola
  - R. Solà
- PubMed: 30262813
- DOI: 10.1038/s41366-018-0220-0
11 Insights on
- High evidence
- Highly Cited
Complementary and alternative medicine for treatment of atopic eczema in children under 14 years old: a systematic review and meta-analysis of randomized controlled trials.
- 2018-09-26
- Meta-Analysis · n = 2,233
- BMC complementary and alternative medicine 18(1)
- - Chun-Li Lu
  - Xue-Han Liu
  - Trine Stub
  - Agnete E Kristoffersen
  - Shi-Bing Liang
  - Xiao Wang
  - Xue Bai
  - Arne Johan Norheim
  - Frauke Musial
  - Terje Alræk.
  - Vinjar Fonnebo
  - Jian-Ping Liu
- PubMed: 30257693
- DOI: 10.1186/s12906-018-2306-6
1 Insight on
- Improved Clinical Symptoms
- High evidence
Prebiotic effects of resistant starch from purple yam (Dioscorea alata L.) on the tolerance and proliferation ability of Bifidobacterium adolescentis in vitro.
- 2018-09-25
- Food & Function 9(4)
- - Tao Li
  - Lei Chen
  - Jianbo Xiao
  - Fengping An
  - C. Wan
  - Hongbo Song
- PubMed: 29620784
- DOI: 10.1039/c7fo01919j
3 Insights on
- Low evidence
Effects of Bifidobacterium probiotic on the treatment of chronic periodontitis: A randomized clinical trial
- 2018-09-24
- RCT · n = 41
- Journal of Clinical Periodontology 45(10)
- - M. Invernici
  - S. Salvador
  - P. Silva
  - M. M. Soares
  - R. Casarin
  - D. Palioto
  - S. Souza
  - M. Taba
  - A. B. Novaes
  - F. Furlaneto
  - M. Messora
- PubMed: 30076613
- DOI: 10.1111/jcpe.12995
7 Insights on
- High evidence
- Highly Cited
- Rigorous Journal
Effects of weight loss using supplementation with Lactobacillus strains on body fat and medium-chain acylcarnitines in overweight individuals.
- 2018-09-24
- RCT · n = 66
- Food & Function 8(1)
- - Minkyung Kim
  - Min-Joo Kim
  - Miso Kang
  - H. J. Yoo
  - Min Sun Kim
  - Y. Ahn
  - J. Sim
  - S. Jee
  - J. H. Lee
- PubMed: 28001147
- DOI: 10.1039/c6fo00993j
5 Insights on
- High evidence
Whole Peptidoglycan Extracts from the Lactobacillus paracasei subsp. paracasei M5 Strain Exert Anticancer Activity In Vitro
- 2018-09-20
- BioMed Research International 2018
- - Shumei Wang
  - Xue Han
  - Lanwei Zhang
  - Yingchun Zhang
  - Hongbo Li
  - Y. Jiao
- PubMed: 29568745
- DOI: 10.1155/2018/2871710
1 Insight on
- Induced Apoptosis
- Low evidence
- Rigorous Journal
In vitro Probiotic Potential and Anti-cancer Activity of Newly Isolated Folate-Producing Streptococcus thermophilus Strains
- 2018-09-19
- Frontiers in Microbiology 9
- - A. Tarrah
  - J. de Castilhos
  - R. Rossi
  - V. Duarte
  - D. Ziegler
  - V. Corich
  - A. Giacomini
- PubMed: 30283428
- DOI: 10.3389/fmicb.2018.02214
6 Insights on
- Low evidence
Lactobacillus plantarum IS-10506 activates intestinal stem cells in a rodent model.
- 2018-09-14
- RCT · n = 64
- Beneficial Microbes 9(5)
- - A. F. Athiyyah
  - A. Darma
  - R. Ranuh
  - W. Riawan
  - A. Endaryanto
  - F. Rantam
  - I. Surono
  - S. Sudarmo
- PubMed: 29726283
- DOI: 10.3920/BM2017.0118
6 Insights on
- Low evidence
- Animal Study
Exopolysaccharide from Bifidobacterium longum subsp. longum 35624™ modulates murine allergic airway responses.
- 2018-09-14
- Clinical Trial
- Beneficial Microbes 9(5)
- - Elisa Schiavi
  - Stephan Plattner
  - Noelia Rodriguez-Perez
  - Weronika Barcik
  - R. Frei
  - Ruth Ferstl
  - Magdalena Kurnik-Lucka
  - D. Groeger
  - R. Grant
  - Jennifer Roper
  - Friedrich Altmann
  - D. Sinderen
  - C. Akdis
  - Liam O'Mahony
- PubMed: 29726281
- DOI: 10.3920/BM2017.0180
2 Insights on
- Modulated Immune Response
- Reduced Respiratory Inflammation Severity
- Low evidence
- Animal Study
Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms: a double-blind, randomised, placebo-controlled study.
- 2018-09-14
- RCT · n = 113
- Beneficial Microbes 9(5)
- - K. Preston
  - R. Krumian
  - J. Hattner
  - D. de Montigny
  - M. Stewart
  - S. Gaddam
- PubMed: 29888656
- DOI: 10.3920/BM2017.0105
3 Insights on
- High evidence
Lactobacillus plantarum C29‐Fermented Soybean (DW2009) Alleviates Memory Impairment in 5XFAD Transgenic Mice by Regulating Microglia Activation and Gut Microbiota Composition
- 2018-09-11
- Clinical Trial
- Molecular Nutrition & Food Research 62(20)
- - Hae-Ji Lee
  - Yun-Ha Hwang
  - Dong-Hyun Kim
- PubMed: 30152045
- DOI: 10.1002/mnfr.201800359
5 Insights on
- Low evidence
- Rigorous Journal
- Animal Study