January 2018 Supplement Research Papers

• January 1

  • Lactobacillus reuteri to Treat Infant Colic: A Meta-analysis

    • 2018-01-01
    • Meta-Analysis
    • Pediatrics 141(1)
    • • V. Sung
      • F. D'Amico
      • M. Cabana
      • Kim Chau
      • G. Koren
      • F. Savino
      • H. Szajewska
      • G. Deshpande
      • C. Dupont
      • F. Indrio
      • S. Mentula
      • Anna Partty
      • D. Tancredi

    • PubMed: 29279326
    • DOI: 10.1542/peds.2017-1811

    11 Insights on

    • Increased Treatment Success for Infant Colic
    • Reduced Crying Time
    • Improved Health in Breastfed Infants
    • Reduced Efficacy of Formula Feeding in Infants
    • Overall Treatment Success
    • Successful Treatment in Breastfed Infants
    • Improved Treatment Success
    • Improved Treatment Success for Colic
    • Improved Colic Symptoms
    • Effectiveness in Breastfed Infants
    • Improved Treatment Success in Infants with Colic

    • High evidence
    • Highly Cited

  • Effect of Probiotic Lactobacillus reuteri on Salivary Cariogenic Bacterial Counts among Groups of Preschool Children in Jeddah, Saudi Arabia: A Randomized Clinical Trial.

    • 2018-01-01
    • RCT · n = 178
    • Journal of Clinical Pediatric Dentistry 42(5)
    • • N. Alamoudi
      • Eman S. Almabadi
      • E. E. El Ashiry
      • D. E. El Derwi

    • PubMed: 29763353
    • DOI: 10.17796/1053-4625-42.5.2

    4 Insights on

    • Reduced Mutans Streptococcus Counts
    • Increased Salivary Buffering Capacity
    • Reduced Formation of Dental Plaque
    • Reduced Lactobacillus Counts

    • High evidence
• January 3

  • Modulation of broilers’ caecal microflora and metabolites in response to a potential probiotic Bacillus amyloliquefaciens

    • 2018-01-03
    • RCT
    • Journal of Animal Physiology and Animal Nutrition 102(2)
    • • G. Cao
      • G. Cao
      • X. Zhan
      • Lingling Zhang
      • X. Zeng
      • A. Chen
      • C. M. Yang

    • PubMed: 29314285
    • DOI: 10.1111/jpn.12856

    3 Insights on

    • Improved Growth Performance
    • Improved Digestibility
    • Improved Intestinal Microflora

    • High evidence
• January 5

  • Herbal medicine for sports: a review.

    • 2018-01-05
    • Review
    • Journal of the International Society of Sports Nutrition 15(1)
    • • Maha Sellami
      • Olfa Slimeni
      • Andrzej Pokrywka
      • Goran Kuvačić
      • Lawrence D Hayes
      • Mirjana Milic
      • Johnny Padulo

    • PubMed: 29568244
    • DOI: 10.1186/s12970-018-0218-y

    3 Insights on

    • Improved Endurance
    • Relieved Muscle Pain
    • Relieved Joint Pain

    • Low evidence
• January 10

  • A census of P. longum’s phytochemicals and their network pharmacological evaluation for identifying novel drug-like molecules against various diseases, with a special focus on neurological disorders

    • 2018-01-10
    • PLOS ONE 13(1)
    • • N. Choudhary
      • Vikram Singh

    • PubMed: 29320554
    • DOI: 10.1371/journal.pone.0191006

    3 Insights on

    • Prevention of Neurological Disorders
    • Identification of FDA Approved Drug Target Regulators
    • Regulation of Neuroactive Ligand Receptor Interaction Pathway

    • Low evidence
    • Rigorous Journal
• January 16

  • The effects of fermented milk containing Lactococcus lactis subsp. cremoris FC on defaecation in healthy young Japanese women: a double-blind, placebo-controlled study

    • 2018-01-16
    • RCT · n = 31
    • International Journal of Food Sciences and Nutrition 69(6)
    • • K. Ozaki
      • T. Maruo
      • H. Kosaka
      • M. Mori
      • H. Mori
      • Y. Yamori
      • T. Toda

    • PubMed: 29336182
    • DOI: 10.1080/09637486.2017.1417977

    4 Insights on

    • Increased Bowel Movement Frequency
    • Increased Stool Volume
    • Improved Stool Frequency
    • Reduced Stool Ammonia Concentration

    • High evidence

  • Beta-Alanine Does Not Enhance the Effects of Resistance Training in Older Adults.

    • 2018-01-16
    • RCT · n = 27
    • Journal of dietary supplements 15(6)
    • • Christopher H Bailey
      • Joseph F Signorile
      • Arlette C Perry
      • Kevin A Jacobs
      • Nicholas D Myers

    • PubMed: 29336621
    • DOI: 10.1080/19390211.2017.1406422

    10 Insights on

    • Improved Anthropometric Measures
    • Improved Muscular Endurance
    • Improved Leg Press 1RM
    • Improved One-Repetition Maximum Leg Press
    • Improved Peak Power
    • Improved Average Power Output During Chest Press
    • Improved Average Power
    • Improved Fatigue Index
    • Improved Leg Press Power
    • Improved Average Power During Leg Press

    • High evidence
• January 25

  • Lactobacillus rhamnosus intake can prevent the development of Candidiasis

    • 2018-01-25
    • RCT
    • Clinical Oral Investigations 22(7)
    • • M. V. P. Leão
      • T. Tavares
      • Célia Regina Gonçalves e Silva
      • Silvana Soleo Ferreira dos Santos
      • J. C. Junqueira
      • L. D. Oliveira
      • A. O. Jorge

    • PubMed: 29372447
    • DOI: 10.1007/s00784-018-2347-8

    5 Insights on

    • Reduced Interleukin-6 Levels
    • Reduced Candida Counts
    • Reduced Fungal Tissue Counts
    • Reduced IL-6 Levels
    • Reduced Fungal Load in Tissues

    • Low evidence
    • Rigorous Journal
    • Animal Study
• January 29

  • Effect of a yoghurt drink containing Lactobacillus strains on bacterial vaginosis in women - a double-blind, randomised, controlled clinical pilot trial.

    • 2018-01-29
    • RCT · n = 36
    • Beneficial Microbes 9(1)
    • • C. Laue
      • E. Papazova
      • A. Liesegang
      • A. Pannenbeckers
      • P. Arendarski
      • B. Linnerth
      • K. Domig
      • W. Kneifel
      • L. Petricevic
      • J. Schrezenmeir

    • PubMed: 29065710
    • DOI: 10.3920/BM2017.0018

    10 Insights on

    • Reduced Recurrence of Bacterial Vaginosis
    • Improved Symptoms of Bacterial Vaginosis
    • Reduced Amsel Score
    • Improved Vaginal Microbial Pattern
    • Improved Vaginal Microbiota Balance
    • Reduced Bacterial Vaginosis
    • Reduced Prevalence of Bacterial Vaginosis
    • Reduced Nugent Score
    • Improved Nugent Score
    • Improved Amsel Score for Bacterial Vaginosis

    • High evidence

  • Bifidobacterium longum BB536 alleviated upper respiratory illnesses and modulated gut microbiota profiles in Malaysian pre-school children.

    • 2018-01-29
    • RCT · n = 520
    • Beneficial Microbes 9(1)
    • • A. Lau
      • N. Yanagisawa
      • Y. Hor
      • L. Lew
      • J. Ong
      • L. Chuah
      • Y-Y Lee
      • S-B Choi
      • F. Rashid
      • N. Wahid
      • H. Sugahara
      • J.‐Z. Xiao
      • M. Liong

    • PubMed: 29065707
    • DOI: 10.3920/BM2017.0063

    7 Insights on

    • Reduced Respiratory Illness
    • Reduced Upper Respiratory Infections
    • Reduced Fever Duration
    • Modulated Gut Microbiota
    • Reduced Sore Throat Duration
    • Reduced Runny Nose Duration
    • Reduced Cough Duration

    • High evidence
    • Large Human Trial

  • Randomised double blind placebo controlled trial on Lactobacillus reuteri DSM 17938: improvement in symptoms and bowel habit in functional constipation.

    • 2018-01-29
    • RCT · n = 56
    • Beneficial Microbes 9(1)
    • • G. Riezzo
      • A. Orlando
      • B. D’Attoma
      • M. Linsalata
      • M. Martulli
      • F. Russo

    • PubMed: 29022390
    • DOI: 10.3920/BM2017.0049

    10 Insights on

    • Improved Stool Consistency
    • Reduced Bloating
    • Reduced Abdominal Pain
    • Reduced Stool Volume
    • Reduced Abdominal Discomfort
    • Improved Constipation
    • Improved Bloating
    • Improved Incomplete Defecation
    • Improved Constipation Severity
    • Improved Pregnancy Outcome

    • High evidence
• January 30

  • Bifidobacterium longum and Lactobacillus helveticus Synergistically Suppress Stress-related Visceral Hypersensitivity Through Hypothalamic-Pituitary-Adrenal Axis Modulation

    • 2018-01-30
    • Clinical Trial
    • Journal of Neurogastroenterology and Motility 24(1)
    • • A. Ait-Belgnaoui
      • Isabelle Payard
      • Claire Rolland
      • C. Harkat
      • V. Braniste
      • V. Théodorou
      • T. Tompkins

    • PubMed: 29291614
    • DOI: 10.5056/jnm16167

    2 Insights on

    • Reduced Visceral Hypersensitivity
    • Improved Glucocorticoid Negative Feedback on the HPA Axis

    • Low evidence
    • Highly Cited
    • Rigorous Journal
    • Animal Study
• Undated – 8 supplement studies

  • l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor-α levels in patients with type 2 diabetes: a double-blind placebo-controlled randomized clinical trial.

    • 2018-01
    • RCT · n = 54
    • Nutrition research (New York, N.Y.) 49
    • • Shiva Houjeghani
      • Sorayya Kheirouri
      • Esmaeil Faraji
      • Mohammad Asghari Jafarabadi

    • PubMed: 29420997
    • DOI: 10.1016/j.nutres.2017.11.003

    22 Insights on

    • Reduced Diastolic Blood Pressure
    • Improved Insulin Sensitivity
    • Reduced Body Mass Index
    • Reduced Low-Density Lipoprotein Level
    • Reduced Tumor Necrosis Factor Alpha
    • Reduced Interleukin-6 Levels
    • Reduced Systolic Blood Pressure
    • Reduced Triglyceride Levels
    • Increased HDL Cholesterol Levels
    • Reduced Body Fat Mass
    • Reduced Insulin Levels
    • Reduced Hemoglobin A1c
    • Reduced Interleukin-1β Levels
    • Reduced Blood Cholesterol
    • Reduced Fasting Blood Glucose Levels
    • Improved Insulin Secretion
    • Reduced Glycated Hemoglobin
    • Increased Fat-Free Mass
    • Reduced Carboxymethyl Lysine
    • Reduced Pentosidine Level
    • Reduced Soluble Receptor of Advanced Glycation End Product Level
    • Increased Soluble Receptor of Advanced Glycation End Products

    • High evidence

  • Lactobacillus rhamnosus L34 Attenuates Gut Translocation-Induced Bacterial Sepsis in Murine Models of Leaky Gut

    • 2018-01
    • Clinical Trial
    • Infection and Immunity 86(1)
    • • Wimonrat Panpetch
      • W. Chancharoenthana
      • Kanthika Bootdee
      • Sumanee Nilgate
      • M. Finkelman
      • S. Tumwasorn
      • A. Leelahavanichkul

    • PubMed: 29038123
    • DOI: 10.1128/IAI.00700-17

    6 Insights on

    • Reduced Gastrointestinal Leakage
    • Reduced Serum IL-6 Levels
    • Reduced Bacteremia
    • Reduced Sepsis Mortality
    • Reduced Fecal Salmonella Bacteria
    • Reduced Cytokine Production in Colonic Epithelial Cells

    • Low evidence
    • Animal Study

  • Clinical Pharmacology of Citrus aurantium and Citrus sinensis for the Treatment of Anxiety.

    • 2018-01
    • Review
    • Evidence-based complementary and alternative medicine : eCAM 2018(1)
    • • Carmen Mannucci
      • Fabrizio Calapai
      • Luigi Cardia
      • Giuseppina Inferrera
      • Giovanni D'Arena
      • Martina Di Pietro
      • Michele Navarra
      • Sebastiano Gangemi
      • Elvira Ventura Spagnolo
      • Gioacchino Calapai

    • PubMed: 30622597
    • DOI: 10.1155/2018/3624094

    1 Insight on

    • Reduced Anxiety

    • Low evidence

  • Comparison of the effects of flaxseed oil and sunflower seed oil consumption on serum glucose, lipid profile, blood pressure, and lipid peroxidation in patients with metabolic syndrome.

    • 2018-01
    • RCT · n = 60
    • Journal of clinical lipidology 12(1)
    • • Atefeh Akrami
      • Farzad Nikaein
      • Siavash Babajafari
      • Shiva Faghih
      • Hassan Yarmohammadi

    • PubMed: 29229363
    • DOI: 10.1016/j.jacl.2017.11.004

    9 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Waist Circumference
    • Reduced Low-Density Lipoprotein Level
    • Reduced Systolic Blood Pressure
    • Reduced Body Weight
    • Reduced Triglyceride Levels
    • Reduced Blood Cholesterol
    • Reduced Fasting Blood Glucose Levels
    • Reduced Malondialdehyde Level

    • High evidence

  • Herbal Medicine in Children With Respiratory Tract Infection: Systematic Review and Meta-Analysis.

    • 2018-01
    • Meta-Analysis · n = 2,181
    • Academic pediatrics 18(1)
    • • Dennis Anheyer
      • Holger Cramer
      • Romy Lauche
      • Felix Joyonto Saha
      • Gustav Dobos

    • PubMed: 28610802
    • DOI: 10.1016/j.acap.2017.06.006

    2 Insights on

    • Prevented Respiratory Tract Infection Symptom
    • Reduced Respiratory Tract Infection Symptom

    • High evidence

  • Effects of dietary Lactobacillus rhamnosus CF supplementation on growth, meat quality, and microenvironment in specific pathogen‐free chickens

    • 2018-01
    • RCT · n = 188
    • Poultry Science 97(1)
    • • Chen Fu
      • S. Gao
      • Lianqin Zhu
      • Shunyi Qin
      • Huiling Qiu

    • PubMed: 29077943
    • DOI: 10.3382/ps/pex261

    19 Insights on

    • Improved Gut Microbiota Composition
    • Improved Body Weight
    • Improved Average Daily Gain
    • Improved Apparent Digestibility of Crude Protein
    • Improved Dressing Percentage
    • Increased Cecal Lactobacilli Levels
    • Increased Muscle Fat Content
    • Reduced Muscle Hydration
    • Reduced Plasma Ammonia Levels
    • Improved Meat Color
    • Improved Thigh Muscle pH Value
    • Improved Growth Performance
    • Reduced Harmful Gut Bacteria
    • Improved Digestive Health
    • Restored Healthy Gut Microbial Balance
    • Improved Microenvironment
    • Improved Digestive Function
    • Improved Digestive Performance
    • Improved Digestive Efficiency

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Review on Sustained Relief of Osteoarthritis Symptoms with a Proprietary Extract from Pine Bark, Pycnogenol.

    • 2018-01
    • Review
    • Journal of medicinal food 21(1)
    • • Peter Jörg Rohdewald

    • PubMed: 28836883
    • DOI: 10.1089/jmf.2017.0015

    7 Insights on

    • Improved Well-Being
    • Reduced Pain
    • Reduced Stiffness
    • Improved Mobility
    • Reduced NSAID Use
    • Reduced Gastric Complication
    • Reduced Hospital Admission Rate

    • Low evidence

  • Antimicrobial and bactericidal impacts of Bacillus amyloliquefaciens CECT 5940 on fecal shedding of pathogenic bacteria in dairy calves and adult dogs.

    • 2018-01
    • RCT · n = 18
    • Microbial Pathogenesis 114
    • • P. Vázquez-Mendoza
      • M. Elghandour
      • P. Alaba
      • P. Sánchez-Aparicio
      • M. U. Alonso-Fresán
      • A. Barbabosa‐Pliego
      • A. Salem

    • PubMed: 29180295
    • DOI: 10.1016/j.micpath.2017.11.040

    1 Insight on

    • Reduced Vaginal Coliforms

    • Low evidence
    • Animal Study