June 2023 Supplement Research Papers

• June 1

  • Essential oils for treating anxiety: a systematic review of randomized controlled trials and network meta-analysis.

    • 2023-06-01
    • Systematic Review · n = 1,815
    • Frontiers in public health 11
    • • Ling Tan
      • Fei-Fei Liao
      • Lin-Zi Long
      • Xiao-Chang Ma
      • Yu-Xuan Peng
      • Jie-Ming Lu
      • Hua Qu
      • Chang-Geng Fu

    • PubMed: 37325306
    • DOI: 10.3389/fpubh.2023.1144404

    2 Insights on

    • Reduced Anxiety
    • Reduced Trait Anxiety

    • High evidence

  • Antagonistic activity of Lactobacillus spp. and Bifidobacterium spp. against cariogenic Streptococcus mutans in vitro and viability when added to chewing gum during storage.

    • 2023-06-01
    • Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] 54(3)
    • • Michelle Barboza Nogueira
      • Khadija Bezerra Massaut
      • Helena Reissig Soares Vitola
      • Maria Fernanda Fernandes Siqueira
      • Wladimir Padilha da Silva
      • Ângela Maria Fiorentini

    • PubMed: 37261620
    • DOI: 10.1007/s42770-023-01021-2

    1 Insight on

    • Reduced Growth of Streptococcus mutans

    • Low evidence
• June 2

  • Whole Genome Sequence of Lactiplantibacillus plantarum HOM3204 and Its Antioxidant Effect on D-Galactose-Induced Aging in Mice

    • 2023-06-02
    • Journal of Microbiology and Biotechnology 33(8)
    • • Di Zhang
      • Hee Shin
      • Tingting Wang
      • Yaxin Zhao
      • Suwon Lee
      • C. Lim
      • Shiqi Zhang

    • PubMed: 37311704
    • DOI: 10.4014/jmb.2209.09021

    1 Insight on

    • Improved Antioxidant Function

    • Low evidence

  • The Effects of Synbiotics on Dextran-Sodium-Sulfate-Induced Acute Colitis: The Impact of Chitosan Oligosaccharides on Endogenous/Exogenous Lactiplantibacillus plantarum

    • 2023-06-02
    • Clinical Trial
    • Foods 12(11)
    • • Yunjiao Zhao
      • L. Xue
      • Shunqin Li
      • Tao Wu
      • R. Liu
      • Wenjie Sui
      • M. Zhang

    • PubMed: 37297494
    • DOI: 10.3390/foods12112251

    13 Insights on

    • Increased Fecal Lactobacilli
    • Reduced Interleukin-6 Levels
    • Reduced Pro-Inflammatory Cytokines
    • Reduced Colitis Symptoms
    • Improved Abundance of Beneficial Bacteria
    • Reduced Interleukin-1β Levels
    • Reduced Myeloperoxidase Activity
    • Reduced Tumor Necrosis Factor-α (TNF-α)
    • Reduced Turicibacter Abundance
    • Inhibited Changes in Short-Chain Fatty Acids
    • Reduced Interleukin-10 Levels
    • Increased Abundance of Muribaculaceae
    • Reduced Relative Abundance of Escherichia-Shigella

    • Low evidence
    • Animal Study
• June 6

  • Bacterial Spore-Based Delivery System: 20 Years of a Versatile Approach for Innovative Vaccines.

    • 2023-06-06
    • Review
    • Biomolecules 13(6)
    • • Rachele Isticato

    • PubMed: 37371527
    • DOI: 10.3390/biom13060947

    1 Insight on

    • Induced Antigen-Specific Protective Mucosal Immune Response

    • Low evidence
• June 9

  • Harnessing the potential of probiotics in the treatment of alcoholic liver disorders.

    • 2023-06-09
    • Review
    • Frontiers in pharmacology 14
    • • Garima Mishra
      • Pradeep Singh
      • Mulugeta Molla
      • Yohannes Shumet Yimer
      • Subas Chandra Dinda
      • Phool Chandra
      • Bhuvnesh Kumar Singh
      • Samuel Berihun Dagnew
      • Abraham Nigussie Assefa
      • Amien Ewunetie

    • PubMed: 37361234
    • DOI: 10.3389/fphar.2023.1212742

    4 Insights on

    • Improved Liver Function
    • Reduced Liver Injury
    • Reduced Liver Disease Progression
    • Improved Alcohol-Associated Liver Disease Parameters

    • Low evidence
• June 11

  • Evaluation of the Effects of Atorvastatin and N-Acetyl Cysteine on Platelet Counts in Patients with Primary Immune Thrombocytopenia: An Exploratory Clinical Trial.

    • 2023-06-11
    • Clinical Trial · n = 15
    • Medicina (Kaunas, Lithuania) 59(6)
    • • Lorena A Cervantes-Pérez
      • Gabino Cervantes-Guevara
      • Enrique Cervantes-Pérez
      • Guillermo Alonso Cervantes-Cardona
      • Adriana Nápoles-Echauri
      • Alejandro González-Ojeda
      • Clotilde Fuentes-Orozco
      • Gabino Cervantes-Pérez
      • Carlos A Reyes-Torres
      • Francisco Javier Hernández-Mora
      • Ana Lucia Ron-Magaña
      • Janet Cristina Vázquez-Beltrán
      • María Isabel Hernández-Rivas
      • Sol Ramírez-Ochoa

    • PubMed: 37374326
    • DOI: 10.3390/medicina59061122

    1 Insight on

    • Increased Platelet Count

    • Moderate evidence
• June 12

  • IgYs: on her majesty's secret service.

    • 2023-06-12
    • Review
    • Frontiers in immunology 14
    • • Renata Grzywa
      • Agnieszka Łupicka-Słowik
      • Marcin Sieńczyk

    • PubMed: 37377972
    • DOI: 10.3389/fimmu.2023.1199427

    3 Insights on

    • Improved Antimicrobial Ability
    • Improved Supplement Tolerance
    • Improved Gut Microbiome Health

    • Low evidence
    • Animal Study
• June 16

  • "In vitro antimicrobial and synergistic effect of fermented Indian zebu (Sahiwal) cow colostrum whey derived peptides with Lactobacillus rhamnosus against pathogenic bacteria".

    • 2023-06-16
    • Journal of food science and technology 60(10)
    • • Daraksha Iram
      • Manish Singh Sansi
      • Sunita Meena
      • Anil Kumar Puniya
      • Shilpa Vij

    • PubMed: 37599850
    • DOI: 10.1007/s13197-023-05776-2

    5 Insights on

    • Reduced Cytotoxic Effects
    • Enhanced Antibacterial Effect
    • Reduced Bacterial Load
    • Increased Bacterial Membrane Permeability
    • Synergistic Antibiotic Effect

    • Low evidence
• June 21

  • The effects of Capsicum annuum supplementation on lipid profiles in adults with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trials.

    • 2023-06-21
    • Meta-Analysis
    • Phytotherapy research : PTR 37(9)
    • • Ahmed Hjazi
      • Ahmed Hjazi
      • Ahmed Hjazi

    • PubMed: 37344950
    • DOI: 10.1002/ptr.7922

    4 Insights on

    • Reduced Low-Density Lipoprotein Level
    • Reduced Triglyceride Levels
    • Increased HDL Cholesterol Levels
    • Reduced Total Cholesterol

    • High evidence
• June 25

  • Polysaccharides from Paecilomyces hepiali Prevent Acute Colitis in Association with Modulating Gut Microbiota and Treg/Th17 Immune Balance in Mice

    • 2023-06-25
    • Clinical Trial
    • Molecules 28(13)
    • • Luwen Cui
      • Ningning He
      • SHENG ‐ SIUNG Yu
      • Hao Pang
      • Zixuan Zhang
      • Jingyi Wang
      • Jianhua Hao
      • Shangyong Li

    • PubMed: 37446646
    • DOI: 10.3390/molecules28134984

    7 Insights on

    • Reduced Colitis Severity
    • Improved Gut Microbiota Balance
    • Reduced Immune Cell Infiltration
    • Restored Normal Microbiota
    • Reduced Incidence of Acute Colitis
    • Balanced Treg/Th17 Regulation
    • Improved Immune Balance

    • Low evidence
    • Animal Study
• June 26

  • Beneficial Effects of Bacillus amyloliquefaciens D1 Soy Milk Supplementation on Serum Biochemical Indexes and Intestinal Health of Bearded Chickens

    • 2023-06-26
    • RCT
    • Microorganisms 11(7)
    • • Liyu Du
      • Weizhe Chen
      • Jie Wang
      • Lingzhu Huang
      • Qikai Zheng
      • Junjie Chen
      • Linhao Wang
      • Changyu Cai
      • Xiangbin Zhang
      • Li Wang
      • Qingping Zhong
      • Wujie Zhong
      • Xiang Fang
      • Zhenlin Liao

    • PubMed: 37512832
    • DOI: 10.3390/microorganisms11071660

    3 Insights on

    • Reduced Inflammation Levels
    • Improved Gut Microbiota Balance
    • Reduced Plasma Lipopolysaccharide Levels

    • High evidence
• June 28

  • Palmitoylethanolamide and acetyl-L-carnitine act synergistically with duloxetine and pregabalin in fibromyalgia: results of a randomised controlled study.

    • 2023-06-28
    • RCT · n = 68
    • Clinical and experimental rheumatology 41(6)
    • • Fausto Salaffi
      • Sonia Farah
      • Piercarlo Sarzi-Puttini
      • Marco Di Carlo

    • PubMed: 37378482
    • DOI: 10.55563/clinexprheumatol/pmdzcq

    4 Insights on

    • Reduced Widespread Pain Index
    • Improved Fibromyalgia Impact Questionnaire Score
    • Improved Fibromyalgia Assessment Status Score
    • Improved Fibromyalgia Assessment Status

    • High evidence

  • Retrospective observational study on the use of acetyl-L-carnitine in ALS.

    • 2023-06-28
    • Observational · n = 45
    • Journal of neurology 270(11)
    • • Serena Sassi
      • Elisa Bianchi
      • Luca Diamanti
      • Danilo Tornabene
      • Elisabetta Sette
      • Doriana Medici
      • Sabrina Matà
      • Deborah Leccese
      • Martina Sperti
      • Ilaria Martinelli
      • Andrea Ghezzi
      • Jessica Mandrioli
      • Valentina Virginia Iuzzolino
      • Raffaele Dubbioso
      • Francesca Trojsi
      • Carla Passaniti
      • Giulia D'Alvano
      • Massimiliano Filosto
      • Alessandro Padovani
      • Letizia Mazzini
      • Fabiola De Marchi
      • Lucia Zinno
      • Andi Nuredini
      • Paolo Bongioanni
      • Cristina Dolciotti
      • Elena Canali
      • Giulia Toschi
      • Antonio Petrucci
      • Alessia Perna
      • Vittorio Riso
      • Maurizio Inghilleri
      • Laura Libonati
      • Chiara Cambieri
      • Elisabetta Pupillo

    • PubMed: 37378756
    • DOI: 10.1007/s00415-023-11844-6

    5 Insights on

    • Improved Survival
    • Improved Forced Vital Capacity
    • Improved Survival at 24 Months
    • Improved ALSFRS-R Score
    • Improved Self-Sufficiency

    • Moderate evidence

  • Biotin induced biochemical hyperthyroidism: a case report and review of the literature.

    • 2023-06-28
    • Review
    • Journal of medical case reports 17(1)
    • • Archa James
      • Jinu Stalan
      • Jose Kuzhively

    • PubMed: 37370185
    • DOI: 10.1186/s13256-023-04002-z

    1 Insight on

    • Increased Thyroid Hormone Level

    • Low evidence
• June 30

  • Gut Microbiota and Critical Metabolites: Potential Target in Preventing Gestational Diabetes Mellitus?

    • 2023-06-30
    • Review
    • Microorganisms 11(7)
    • • Runan Hu
      • Zhuo Liu
      • Yuli Geng
      • Yanjing Huang
      • Fan Li
      • Haoxu Dong
      • Wenwen Ma
      • Kunkun Song
      • Mingmin Zhang
      • Yufan Song

    • PubMed: 37512897
    • DOI: 10.3390/microorganisms11071725

    1 Insight on

    • No Human Health Outcome Reported

    • Low evidence
• Undated – 4 supplement studies

  • Probiotics and their postbiotics for the control of opportunistic fungal pathogens: A review.

    • 2023-06
    • Review
    • Biotechnology reports (Amsterdam, Netherlands) 38
    • • S Divyashree
      • B Shruthi
      • P R Vanitha
      • M Y Sreenivasa

    • PubMed: 37215743
    • DOI: 10.1016/j.btre.2023.e00800

    1 Insight on

    • Reduced Opportunistic Pathogens

    • Low evidence

  • Bromelain supplementation and inflammatory markers: A systematic review of clinical trials.

    • 2023-06
    • Systematic Review
    • Clinical nutrition ESPEN 55
    • • Irislene Costa Pereira
      • Eduardo Emanuel Sátiro Vieira
      • Lucillia Rabelo de Oliveira Torres
      • Felipe Cavalcanti Carneiro da Silva
      • João Marcelo de Castro E Sousa
      • Francisco Leonardo Torres-Leal

    • PubMed: 37202035
    • DOI: 10.1016/j.clnesp.2023.02.028

    2 Insights on

    • Reduced Prostaglandin E2 Level
    • Reduced Interleukin-12 Level

    • High evidence

  • Benefits of fermented synbiotic soymilk containing Lactobacillus acidophilus, Bifidobacterium lactis, and inulin towards lead toxicity alleviation.

    • 2023-06
    • Heliyon 9(6)
    • • Maryamsadat Riasatian
      • Seyed Mohammad Mazloomi
      • Afsane Ahmadi
      • Zahra Derakhshan
      • Saeed Rajabi

    • PubMed: 37408889
    • DOI: 10.1016/j.heliyon.2023.e17518

    1 Insight on

    • Reduced Serum Lead Levels

    • Low evidence

  • Phytotherapy in paediatric skin disorders - A systematic literature review.

    • 2023-06
    • Systematic Review · n = 2,358
    • Complementary therapies in medicine 74
    • • Evelyne Kloter
      • Fiorella Albanese
      • Reka Schweighoffer
      • Ursula Wolf

    • PubMed: 36958415
    • DOI: 10.1016/j.ctim.2023.102942

    1 Insight on

    • Improved Wound Healing

    • High evidence