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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Effects of Oral Administration of Lactobacillus acidophilus L-92 on the Symptoms and Serum Cytokines of Atopic Dermatitis in Japanese Adults: A Double-Blind, Randomized, Clinical Trial
- 2015-04-16
- RCT · n = 49
- International Archives of Allergy and Immunology 165(4)
- - Y. Inoue
  - T. Kambara
  - Naoko Murata
  - J. Komori-Yamaguchi
  - S. Matsukura
  - Yukitoshi Takahashi
  - Z. Ikezawa
  - M. Aihara
- PubMed: 25660281
- DOI: 10.1159/000369806
3 Insights on
- High evidence
Effects of Bifidobacterium supplementation on intestinal microbiota composition and the immune response in healthy infants
- 2015-04-06
- RCT · n = 300
- World Journal of Pediatrics 12(2)
- - Bingbing Wu
  - Yi Yang
  - Xiu Xu
  - Weiping Wang
- PubMed: 25846071
- DOI: 10.1007/s12519-015-0025-3
2 Insights on
- Improved Immune Response
- Improved Intestinal Microbial Composition
- High evidence
- Large Human Trial
Applications of Microencapsulated Bifidobacterium Longum with Eleutherine Americana in Fresh Milk Tofu and Pineapple Juice
- 2015-04-03
- Nutrients 7(4)
- - A. Phoem
  - S. Chanthachum
  - S. Voravuthikunchai
- PubMed: 25854832
- DOI: 10.3390/nu7042469
5 Insights on
- Moderate evidence
Effect of Long-Term Consumption of Lactobacillus paracasei SD1 on Reducing Mutans streptococci and Caries Risk: A Randomized Placebo-Controlled Trial
- 2015-04-01
- RCT · n = 122
- Dentistry Journal 3(2)
- - R. Teanpaisan
  - S. Piwat
  - S. Tianviwat
  - B. Sophatha
  - Thanyanan Kampoo
- PubMed: 29567924
- DOI: 10.3390/dj3020043
9 Insights on
- High evidence
- Rigorous Journal
A lactose fermentation product produced by Lactococcus lactis subsp. lactis, acetate, inhibits the motility of flagellated pathogenic bacteria.
- 2015-04-01
- Microbiology 161(4)
- - Shuichi Nakamura
  - Yusuke V. Morimoto
  - S. Kudo
- PubMed: 25573770
- DOI: 10.1099/mic.0.000031
4 Insights on
- Low evidence
Effect of iron on the probiotic properties of the vaginal isolate Lactobacillus jensenii CECT 4306.
- 2015-04-01
- Microbiology 161(4)
- - Rebeca Martín
  - B. Sánchez
  - M. Urdaci
  - P. Langella
  - J. Suárez
  - L. Bermúdez-Humarán
- PubMed: 25635270
- DOI: 10.1099/mic.0.000044
1 Insight on
- Increased Anti-Inflammatory Cytokine Levels
- Low evidence
Assessment of probiotic, antifungal and cholesterol lowering properties of Pediococcus pentosaceus KCC-23 isolated from Italian ryegrass.
- 2015-03-21
- Journal of the Science of Food and Agriculture 96(2)
- - S. Ilavenil
  - M. Vijayakumar
  - D. H. Kim
  - M. Valan Arasu
  - Hyung-Su Park
  - S. Ravikumar
  - K. Choi
- PubMed: 25655225
- DOI: 10.1002/jsfa.7128
4 Insights on
- Low evidence
- Rigorous Journal
Use of bacteriocin‐producing, probiotic strain Enterococcus faecium AL41 to control intestinal microbiota in farm ostriches
- 2015-03-20
- RCT · n = 92
- Letters in Applied Microbiology 60(6)
- - A. Lauková
  - A. Kandričáková
  - J. Ščerbová
- PubMed: 25732357
- DOI: 10.1111/lam.12409
1 Insight on
- Reduced Harmful Gut Bacteria
- Low evidence
- Animal Study
The effect of vitamin K1 supplementation on sensitivity and insulin resistance via osteocalcin in prediabetic women: a double-blind randomized controlled clinical trial.
- 2015-03-18
- RCT · n = 43
- European journal of clinical nutrition 69(8)
- - H Rasekhi
  - M Karandish
  - M T Jalali
  - M Mohammad-Shahi
  - M Zarei
  - A Saki
  - H Shahbazian
- PubMed: 25782427
- DOI: 10.1038/ejcn.2015.17
5 Insights on
- High evidence
- Rigorous Journal
A highly acid-resistant novel strain of Lactobacillus johnsonii No. 1088 has antibacterial activity, including that against Helicobacter pylori, and inhibits gastrin-mediated acid production in mice
- 2015-03-15
- MicrobiologyOpen 4(3)
- - Y. Aiba
  - Y. Nakano
  - Y. Koga
  - Kenji Takahashi
  - Y. Komatsu
- PubMed: 25771812
- DOI: 10.1002/mbo3.252
5 Insights on
- Low evidence
Amelioration of Colitis in Mouse Model by Exploring Antioxidative Potentials of an Indigenous Probiotic Strain of Lactobacillus fermentum Lf1
- 2015-03-12
- Clinical Trial
- BioMed Research International 2014
- - Ritu Chauhan
  - A. Vasanthakumari
  - Harsh Panwar
  - R. H. Mallapa
  - R. Duary
  - V. Batish
  - S. Grover
- PubMed: 25061603
- DOI: 10.1155/2014/206732
2 Insights on
- Reduced Colitis Severity
- Reduced Serum Malondialdehyde Levels
- Low evidence
- Animal Study
Oral Administration of Lactococcus lactis Subsp. lactis JCM5805 Enhances Lung Immune Response Resulting in Protection from Murine Parainfluenza Virus Infection
- 2015-03-06
- Clinical Trial
- PLOS ONE 10(3)
- - K. Jounai
  - Tetsu Sugimura
  - Konomi Ohshio
  - Daisuke Fujiwara
- PubMed: 25746923
- DOI: 10.1371/journal.pone.0119055
6 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Vitamin B2 intake and the risk of colorectal cancer: a meta-analysis of observational studies.
- 2015-03-04
- Meta-Analysis
- Asian Pacific journal of cancer prevention : APJCP 16(3)
- - Yan Liu
  - Qiu-Yan Yu
  - Zhen-Li Zhu
  - Ping-Yi Tang
  - Ke Li
- PubMed: 25735381
- DOI: 10.7314/apjcp.2015.16.3.909
1 Insight on
- Reduced Risk of Colorectal Cancer
- High evidence
Salacia reticulata (Kothala himbutu) revisited; a missed opportunity to treat diabetes and obesity?
- 2015-02-27
- Review
- Nutrition journal 14
- - Arjuna B Medagama
- PubMed: 25889885
- DOI: 10.1186/s12937-015-0013-4
5 Insights on
- Low evidence
A17, the First Sequenced Strain of Lactococcus lactis subsp. cremoris with Potential Immunomodulatory Functions
- 2015-02-26
- Genome Announcements 3(1)
- - Chih-Hsien Yang
  - Chien-Chen Wu
  - Wei-Shen Cheng
  - Ming-Chuan Chung
  - Y. Tsai
  - Chuan-Hsiung Chang
- PubMed: 25676767
- DOI: 10.1128/genomeA.01563-14
2 Insights on
- Improved Immunomodulation
- Improved Antiallergic Function
- Low evidence
Probiotics (Lactobacillus rhamnosus R0011 and acidophilus R0052) reduce the expression of toll-like receptor 4 in mice with alcoholic liver disease.
- 2015-02-18
- PloS one 10(2)
- - Meegun Hong
  - Seung Woo Kim
  - Sang Hak Han
  - Dong Joon Kim
  - Ki Tae Suk
  - Yeon Soo Kim
  - Myong Jo Kim
  - Moon Young Kim
  - Soon Koo Baik
  - Young Lim Ham
- PubMed: 25692549
- DOI: 10.1371/journal.pone.0117451
2 Insights on
- Reduced Pro-Inflammatory Cytokines
- Increased Anti-Inflammatory Cytokine IL-10
- Low evidence
- Animal Study
Long-term safety of early consumption of Lactobacillus fermentum CECT5716: A 3-year follow-up of a randomized controlled trial.
- 2015-02-16
- RCT
- Pharmacological research 95
- - J A Maldonado-Lobón
  - M Gil-Campos
  - J Maldonado
  - E López-Huertas
  - K Flores-Rojas
  - A D Valero
  - M V Rodríguez-Benítez
  - O Bañuelos
  - F Lara-Villoslada
  - J Fonollá
  - M Olivares
- PubMed: 25697549
- DOI: 10.1016/j.phrs.2015.01.006
2 Insights on
- Improved Gut Microbiota Composition
- Improved Growth in Children
- High evidence
Safety Characterization and Antimicrobial Properties of Kefir-Isolated Lactobacillus kefiri
- 2015-02-12
- Clinical Trial
- BioMed Research International 2014
- - P. Carasi
  - M. Díaz
  - S. Racedo
  - G. D. De Antoni
  - M. Urdaci
  - M. Serradell
- PubMed: 24955346
- DOI: 10.1155/2014/208974
6 Insights on
- Low evidence
- Animal Study
Relationships between the genome and some phenotypical properties of Lactobacillus fermentum CECT 5716, a probiotic strain isolated from human milk
- 2015-02-10
- Applied Microbiology and Biotechnology 99(10)
- - Nívia Cárdenas
  - J. Laiño
  - S. Delgado
  - E. Jiménez
  - Marianela Juárez del Valle
  - Graciela Savoy De Giori
  - F. Sesma
  - B. Mayo
  - L. Fernández
  - J. G. LeBlanc
  - J. M. Rodríguez
- PubMed: 25661998
- DOI: 10.1007/s00253-015-6429-0
7 Insights on
- Low evidence
Comparison between three different saliva substitutes in patients with hyposalivation.
- 2015-01-25
- RCT · n = 60
- Clinical oral investigations 19(3)
- - Ivana Skrinjar
  - Vanja Vucicevic Boras
  - Iva Bakale
  - Ana Andabak Rogulj
  - Vlaho Brailo
  - Danica Vidovic Juras
  - Ivan Alajbeg
  - Danko Velimir Vrdoljak
- PubMed: 25617026
- DOI: 10.1007/s00784-015-1405-8
2 Insights on
- Improved Quality of Life
- Reduced Dry Mouth Intensity
- High evidence
Bifidobacterium bifidum R0071 results in a greater proportion of healthy days and a lower percentage of academically stressed students reporting a day of cold/flu: a randomised, double-blind, placebo-controlled study
- 2015-01-21
- RCT · n = 581
- British Journal of Nutrition 113(3)
- - B. Langkamp-Henken
  - C. Rowe
  - A. Ford
  - M. Christman
  - C. Nieves
  - Lauren Khouri
  - Gretchen J. Specht
  - S. Girard
  - Samuel J. Spaiser
  - W. Dahl
- PubMed: 25604727
- DOI: 10.1017/S0007114514003997
5 Insights on
- High evidence
- Large Human Trial
Maternal intake of Natto, a Japan's traditional fermented soybean food, during pregnancy and the risk of eczema in Japanese babies.
- 2015-01-09
- Observational · n = 650
- Allergology International 63(2)
- - Naoko Ozawa
  - N. Shimojo
  - Yoichi Suzuki
  - Shingo Ochiai
  - T. Nakano
  - Y. Morita
  - Y. Inoue
  - T. Arima
  - Shuichi Suzuki
  - Y. Kohno
- PubMed: 24759553
- DOI: 10.2332/allergolint.13-OA-0613
2 Insights on
- Reduced Infant Eczema
- Reduced Eczema Incidence
- High evidence
Changes in bile acids, FGF-19 and sterol absorption in response to bile salt hydrolase active L. reuteri NCIMB 30242
- 2015-01-02
- RCT · n = 14
- Gut Microbes 6(1)
- - C. Martoni
  - A. Labbé
  - J. Ganopolsky
  - S. Prakash
  - M. Jones
- PubMed: 25612224
- DOI: 10.1080/19490976.2015.1005474
8 Insights on
- High evidence
- Rigorous Journal
Safety of Bifidobacterium animalis subsp. lactis (B. lactis) strain BB-12-supplemented yogurt in healthy adults on antibiotics: a phase I safety study
- 2015-01-02
- RCT · n = 40
- Gut Microbes 6(1)
- - D. Merenstein
  - T. Tan
  - Aleksey Molokin
  - K. H. Smith
  - R. Roberts
  - N. Shara
  - M. Mete
  - M. Sanders
  - G. Solano-Aguilar
- PubMed: 25569274
- DOI: 10.1080/19490976.2015.1005484
5 Insights on
- High evidence
- Rigorous Journal
Lactobacillus acidophilus ATCC 4356 inhibits biofilm formation by C. albicans and attenuates the experimental candidiasis in Galleria mellonella
- 2015-01-02
- Virulence 6(1)
- - S. F. Vilela
  - J. Barbosa
  - R. D. Rossoni
  - J. D. Santos
  - M. C. A. Prata
  - A. Anbinder
  - A. O. Jorge
  - J. C. Junqueira
- PubMed: 25654408
- DOI: 10.4161/21505594.2014.981486
2 Insights on
- Reduced Candida albicans Colony-Forming Units
- Increased Survival Rate During Candidiasis
- Low evidence
- Highly Cited
Safety and efficacy of human breast milk Lactobacillus fermentum CECT 5716. A mini-review of studies with infant formulae.
- 2015-01-01
- Review
- Beneficial Microbes 6(2)
- - E. López-Huertas
- PubMed: 25519525
- DOI: 10.3920/BM2014.0091
1 Insight on
- Reduced Community-Acquired Infection Incidence
- Low evidence
The effect of Lactobacillus paracasei subsp. paracasei L. casei W8® on blood levels of triacylglycerol is independent of colonisation.
- 2015-01-01
- RCT · n = 64
- Beneficial Microbes 6(3)
- - A. T. Bjerg
  - M. Sørensen
  - L. Krych
  - L. Hansen
  - A. Astrup
  - M. Kristensen
  - D. Nielsen
- PubMed: 25273547
- DOI: 10.3920/BM2014.0033
2 Insights on
- Reduced Triglyceride Levels
- Reduced Serum Triacylglycerols
- High evidence
Bifidobacterium infantis has a beneficial effect on 5-fluorouracil-induced intestinal mucositis in rats.
- 2015-01-01
- RCT · n = 30
- Beneficial Microbes 6(1)
- - Kai-Tao Yuan
  - Honglan Yu
  - W. Feng
  - P. Chong
  - T. Yang
  - Conglong Xue
  - M. Yu
  - Houyin Shi
- PubMed: 25380796
- DOI: 10.3920/BM2013.0095
4 Insights on
- Low evidence
- Animal Study
Preventive effects of oral probiotic on infantile colic: a prospective, randomised, blinded, controlled trial using Lactobacillus reuteri DSM 17938.
- 2015-01-01
- RCT · n = 138
- Beneficial microbes 6(3)
- - F Savino
  - S Ceratto
  - E Poggi
  - M E Cartosio
  - L Cordero di Montezemolo
  - A Giannattasio
- PubMed: 25488262
- DOI: 10.3920/bm2014.0090
4 Insights on
- High evidence
- Large Human Trial
- Rigorous Journal
Evaluation of Bacillus subtilis R0179 on gastrointestinal viability and general wellness: a randomised, double-blind, placebo-controlled trial in healthy adults.
- 2015-01-01
- RCT · n = 81
- Beneficial Microbes 6(1)
- - A. Hanifi
  - T. Culpepper
  - Volker Mai
  - Anshu Anand
  - A. Ford
  - M. Ukhanova
  - M. Christman
  - Thomas A. Tompkins
  - Wendy J. Dahl
- PubMed: 25062611
- DOI: 10.3920/BM2014.0031
5 Insights on
- High evidence