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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Conjugated Linoleic Acid Production in Pine Nut Oil: A Lactiplantibacillus plantarum Lp-01 Fermentation Approach.
- 2024-08-06
- Foods (Basel, Switzerland) 13(16)
- - Gang Wei
  - Ge Wu
  - Jiajia Sun
  - Yi Qi
  - Qi Zhao
  - Fengde Xu
  - Zhi Zhang
  - Lanzhi Peng
- PubMed: 39200400
- DOI: 10.3390/foods13162472
1 Insight on
- Increased Conjugated Linoleic Acid Production
- Low evidence
The effects of N-acetyl cysteine on intrinsic functional connectivity and neural alcohol cue reactivity in treatment-seeking individuals with alcohol use disorder: a preliminary study.
- 2024-08-05
- RCT · n = 14
- Psychopharmacology 242(1)
- - Warren B Logge
  - Paul S Haber
  - Tristan P Hurzeler
  - Ellen E Towers
  - Kirsten C Morley
- PubMed: 39102049
- DOI: 10.1007/s00213-024-06656-z
1 Insight on
- Reduced Craving
- High evidence
Systematic review and meta-analysis of the effect of N-acetylcysteine on outcomes after liver resection.
- 2024-08-05
- Meta-Analysis · n = 388
- ANZ journal of surgery 94(10)
- - Amanda Koh
  - Tiffany Wong
  - Alfred Adiamah
  - Sudip Sanyal
- PubMed: 39101362
- DOI: 10.1111/ans.19183
6 Insights on
- High evidence
The effects of raspberry consumption on anthropometric indices and liver function tests in adults: a GRADE-assessed systematic review and meta-analysis.
- 2024-08-05
- Systematic Review · n = 355
- Frontiers in nutrition 11
- - Mostafa Shahraki Jazinaki
  - Hanieh Barghchi
  - Pegah Rahbarinejad
  - Naseh Pahlavani
- PubMed: 39161910
- DOI: 10.3389/fnut.2024.1419417
5 Insights on
- High evidence
Nutrition, Obesity, and Seborrheic Dermatitis: Systematic Review.
- 2024-08-05
- Systematic Review · n = 906
- JMIR dermatology 7
- - Emily Woolhiser
  - Noah Keime
  - Arya Patel
  - Isaac Weber
  - Madeline Adelman
  - Robert P Dellavalle
- PubMed: 39102684
- DOI: 10.2196/50143
2 Insights on
- Improved Patient Satisfaction
- Decreased Scalp Sebum Level
- High evidence
Nonantibiotic prophylaxis for urinary tract infections: a network meta-analysis of randomized controlled trials.
- 2024-08-02
- Systematic Review · n = 495
- Infection 53(2)
- - Zeyu Han
  - Xianyanling Yi
  - Jin Li
  - Dazhou Liao
  - Jianzhong Ai
- PubMed: 39095666
- DOI: 10.1007/s15010-024-02357-z
1 Insight on
- Reduced Urinary Tract Infection
- High evidence
The Potential of Bacillus Species as Probiotics in the Food Industry: A Review.
- 2024-08-02
- Review
- Foods (Basel, Switzerland) 13(15)
- - Jessie Payne
  - Danielle Bellmer
  - Ravi Jadeja
  - Peter Muriana
- PubMed: 39123635
- DOI: 10.3390/foods13152444
5 Insights on
- Low evidence
A randomized double-blind controlled clinical trial demonstrating efficacy of different probiotic strains on serum lipids and glycemic biomarker.
- 2024-08-01
- RCT · n = 51
- Nutricion hospitalaria 41(4)
- - Gözde Okburan
  - Murat Baş
  - Sultan Ogmen
- PubMed: 38967303
- DOI: 10.20960/nh.04724
5 Insights on
- High evidence
A randomized, double-blind, placebo-controlled study to evaluate the benefits of a standardized Nigella sativa oil containing 5% thymoquinone in reducing the symptoms of seasonal allergy.
- 2024-08-01
- RCT · n = 65
- Medicine 103(32)
- - Anju Majeed
  - Shaheen Majeed
  - Avinash Kadasiddappa Parameswarappa
  - Avinash Murali
  - Satish Gudimallam
  - Chikkalingaiah Siddegowda
  - Harshith Chandrashekar
  - Lakshmi Mundkur
- PubMed: 39121267
- DOI: 10.1097/md.0000000000039243
3 Insights on
- High evidence
Persimmon Fiber-Rich Ingredients Promote Anti-Inflammatory Responses and the Growth of Beneficial Anti-Inflammatory Firmicutes Species from the Human Colon.
- 2024-08-01
- Nutrients 16(15)
- - Lucía López-Bermudo
  - Bryan Moreno-Chamba
  - Julio Salazar-Bermeo
  - Nicholas J Hayward
  - Amanda Morris
  - Gary J Duncan
  - Wendy R Russell
  - Antonio Cárdenas
  - Ángeles Ortega
  - Blanca Escudero-López
  - Genoveva Berná
  - Nuria Martí Bruña
  - Sylvia H Duncan
  - Madalina Neacsu
  - Franz Martin
- PubMed: 39125398
- DOI: 10.3390/nu16152518
3 Insights on
- Low evidence
- Rigorous Journal
The effects of L-carnitine supplementation on cardiovascular risk factors in participants with impaired glucose tolerance and diabetes: a systematic review and dose-response meta-analysis.
- 2024-07-31
- Review · n = 2,900
- Diabetology & metabolic syndrome 16(1)
- - Rezvan Gheysari
  - Mahlagha Nikbaf-Shandiz
  - Amir Mehdi Hosseini
  - Niloufar Rasaei
  - Shabnam Hosseini
  - Hossein Bahari
  - Omid Asbaghi
  - Samira Rastgoo
  - Kian Goudarzi
  - Farideh Shiraseb
  - Reza Behmadi
- PubMed: 39085907
- DOI: 10.1186/s13098-024-01415-8
11 Insights on
- High evidence
Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
- 2024-07-31
- Meta-Analysis · n = 254
- Human psychopharmacology 39(6)
- - Kaneez Fatima
  - Javeria Malik
  - Fariha Muskan
  - Ghana Raza
  - Areesha Waseem
  - Hiba Shahid
  - Syeda Fatima Jaffery
  - Umeed Khan
  - Muhammad Kashan Zaheer
  - Yasmeen Shaikh
  - Ahmed Mustafa Rashid
- PubMed: 39083548
- DOI: 10.1002/hup.2911
7 Insights on
- High evidence
Flavan-3-ols and Vascular Health: Clinical Evidence and Mechanisms of Action.
- 2024-07-30
- Review
- Nutrients 16(15)
- - Justyna Godos
  - Giovanni Luca Romano
  - Samuele Laudani
  - Lucia Gozzo
  - Ida Guerrera
  - Irma Dominguez Azpíroz
  - Raquel Martínez Diaz
  - José L Quiles
  - Maurizio Battino
  - Filippo Drago
  - Francesca Giampieri
  - Fabio Galvano
  - Giuseppe Grosso
- PubMed: 39125353
- DOI: 10.3390/nu16152471
2 Insights on
- Reduced Blood Pressure
- Improved Vascular Endothelial Function
- Moderate evidence
- Rigorous Journal
Silk Sericin and Its Effect on Skin Wound Healing: A State of the Art.
- 2024-07-29
- Review
- Macromolecular bioscience 24(10)
- - Łukasz Mazurek
  - Mateusz Rybka
  - Jan Jurak
  - Jakub Frankowski
  - Marek Konop
- PubMed: 39073276
- DOI: 10.1002/mabi.202400145
1 Insight on
- Improved Wound Healing
- Low evidence
Lactobacillus rhamnosus GG as a probiotic for preterm infants: a strain specific systematic review and meta-analysis.
- 2024-07-26
- Meta-Analysis · n = 1,037
- European journal of clinical nutrition 78(10)
- - Anitha Ananthan
  - Haribalakrishna Balasubramanian
  - Chandra Rath
  - Saravanan Muthusamy
  - Shripada Rao
  - Sanjay Patole
- PubMed: 39060543
- DOI: 10.1038/s41430-024-01474-0
5 Insights on
- High evidence
- Rigorous Journal
Multicenter, Open-Label, Prospective Study Shows Safety and Therapeutic Benefits of a Defined Ginkgo Biloba Extract for Adults with Major Neurocognitive Disorder.
- 2024-07-26
- Clinical Trial · n = 150
- Dementia and geriatric cognitive disorders 53(6)
- - Debashish Chowdhury
  - Ajit Kumar Roy
  - V Radhika Reddy
  - Yogesh Kumar Gupta
  - Pushkar Nigam
  - Robert Hoerr
- PubMed: 39068924
- DOI: 10.1159/000540385
5 Insights on
- High evidence
- Large Human Trial
Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.
- 2024-07-25
- RCT
- Nutritional neuroscience 28(4)
- - Umangi W Karunaratne
  - Tharaka L Dassanayake
- PubMed: 39052627
- DOI: 10.1080/1028415x.2024.2383080
4 Insights on
- High evidence
Use of Streptococcus Salivarius K12 in a cohort of PFAPA patients.
- 2024-07-25
- Observational · n = 117
- Frontiers in pediatrics 12
- - Alessandra Spagnolo
  - Vincenzo Mileto
  - Adele Civino
  - Maria Cristina Maggio
  - Paolo Risso
  - Simona Sestito
  - Romina Gallizzi
- PubMed: 39119192
- DOI: 10.3389/fped.2024.1370544
8 Insights on
- High evidence
Segmental Acupuncture for Prevention of Recurrent Urinary Tract Infections. A Randomised Clinical Trial.
- 2024-07-25
- RCT · n = 137
- International urogynecology journal 35(8)
- - Thomas Ots
  - Daniela Gold
  - Paul Ziller
  - Thomas Kuenzer
  - Orietta Dalpiaz
  - Lejla Pesto
  - Gerda Trutnovsky
- PubMed: 39060726
- DOI: 10.1007/s00192-024-05872-7
1 Insight on
- Reduced Urinary Tract Infection
- High evidence
- Large Human Trial
Postbiotics as Adjuvant Therapy in Cancer Care.
- 2024-07-24
- Review
- Nutrients 16(15)
- - Vyshnavy Balendra
  - Roberto Rosenfeld
  - Chiara Amoroso
  - Cecilia Castagnone
  - Maria Grazia Rossino
  - Ornella Garrone
  - Michele Ghidini
- PubMed: 39125280
- DOI: 10.3390/nu16152400
1 Insight on
- Improved Cancer-Related Health Outcome
- Moderate evidence
- Rigorous Journal
Health Effects of Various Edible Vegetable Oil: An Umbrella Review.
- 2024-07-23
- Systematic Review · n = 48
- Advances in nutrition (Bethesda, Md.) 15(9)
- - Phooi Tee Voon
  - Choon Ming Ng
  - Yen Teng Ng
  - Yen Jun Wong
  - Sia Yen Yap
  - Siew Lian Leong
  - Xiou Shuang Yong
  - Shaun Wen Huey Lee
- PubMed: 39053603
- DOI: 10.1016/j.advnut.2024.100276
8 Insights on
- High evidence
Effect of inhaled aromatherapy on sleep quality in critically ill patients: A systematic review and network meta-analysis.
- 2024-07-23
- Systematic Review · n = 11
- Journal of clinical nursing 34(3)
- - Chiu-Shu Fang
  - Yu-Kang Tu
  - Fan-Hao Chou
  - Ching-Ju Fang
  - Shih-Lun Chang
- PubMed: 39041491
- DOI: 10.1111/jocn.17368
1 Insight on
- Improved Sleep Quality
- High evidence
Immediate and residual effects of functional chewing gum on sustained attention and mood.
- 2024-07-23
- RCT
- Nutritional neuroscience 28(4)
- - Emily Haworth
  - Crystal F Haskell-Ramsay
- PubMed: 39039933
- DOI: 10.1080/1028415x.2024.2379698
1 Insight on
- Reduced Digit Vigilance Task Error
- High evidence
The beneficial effect of probiotics in the prevention of irinotecan-induced diarrhea in colorectal cancer patients with colostomy: a pooled analysis of two probiotic trials (Probio-SK-003 and Probio-SK-005) led by Slovak Cooperative Oncology Group.
- 2024-07-22
- RCT · n = 279
- Frontiers in oncology 14
- - Michal Mego
  - Barbora Kasperova
  - Jozef Chovanec
  - Radoslav Danis
  - Maria Reckova
  - Branislav Bystricky
  - Peter Konkolovsky
  - Silvia Jurisova
  - Stefan Porsok
  - Vladimir Vaclav
  - Maria Wagnerova
  - Marian Stresko
  - Bibiana Brezinova
  - Dagmar Sutekova
  - Sona Ciernikova
  - Daniela Svetlovska
  - Lubos Drgona
- PubMed: 39104721
- DOI: 10.3389/fonc.2024.1438657
1 Insight on
- Reduced Diarrhea
- High evidence
The effect of probiotics and casein supplementation on aerobic capacity parameters of male soccer players.
- 2024-07-22
- RCT
- Journal of the International Society of Sports Nutrition 21(1)
- - Babak Imanian
  - Mohammad Hemmatinafar
  - Farhad Daryanoosh
  - Negar Koureshfard
  - Reza Sadeghi
  - Alireza Niknam
  - Rasoul Rezaei
  - Ali Qashqaei
- PubMed: 39039903
- DOI: 10.1080/15502783.2024.2382165
2 Insights on
- Increased Hypocapnic Hyperventilation Area Time
- Improved Anaerobic Capacity
- High evidence
Effects of Hesperidin Supplementation on Cardiometabolic Markers: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
- 2024-07-22
- Meta-Analysis
- Nutrition reviews 83(3)
- - Zeinab Heidari
  - Fatemeh Farahmandpour
  - Hadi Bazyar
  - Fereshteh Pashayee-Khamene
- PubMed: 39038797
- DOI: 10.1093/nutrit/nuae084
6 Insights on
- High evidence
Lactobacillus reuteri DSM 17938 Improves Feeding Intolerance in Preterm Infants
- 2024-07-22
- RCT · n = 94
- Pediatric Gastroenterology, Hepatology & Nutrition 22(6)
- - Risma K Kaban
  - Wardhana
  - B. Hegar
  - R. Rohsiswatmo
  - S. Handryastuti
  - Novie Amelia
  - D. Muktiarti
  - F. Indrio
  - Y. Vandenplas
- PubMed: 31777720
- DOI: 10.5223/pghn.2019.22.6.545
3 Insights on
- High evidence
- Rigorous Journal
Natural Products as Hepatoprotective Agents-A Comprehensive Review of Clinical Trials.
- 2024-07-20
- Review
- Plants (Basel, Switzerland) 13(14)
- - Piotr Służały
  - Paweł Paśko
  - Agnieszka Galanty
- PubMed: 39065511
- DOI: 10.3390/plants13141985
1 Insight on
- Reduced Liver Enzyme Levels
- Low evidence
Investigating the Effects and Mechanisms of Combined Vitamin D and K Supplementation in Postmenopausal Women: An Up-to-Date Comprehensive Review of Clinical Studies.
- 2024-07-20
- Review
- Nutrients 16(14)
- - Marius Emil Rusu
  - Galya Bigman
  - Alice S Ryan
  - Daniela-Saveta Popa
- PubMed: 39064799
- DOI: 10.3390/nu16142356
2 Insights on
- Improved Cardiovascular Health
- Improved Bone Health
- Moderate evidence
- Rigorous Journal
Effects and safety of Ophiocordyceps sinensis preparation in the adjuvant treatment for dialysis patients: a systematic review and meta-analysis.
- 2024-07-19
- Systematic Review · n = 914
- Frontiers in pharmacology 15
- - Meixi Liu
  - Chengji Cui
  - Tianying Chang
  - Qingshan Zhou
  - Yingzi Cui
  - Shoulin Zhang
  - Xing Liao
- PubMed: 39101133
- DOI: 10.3389/fphar.2024.1360997
5 Insights on
- High evidence