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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

The serotonin receptor mediates changes in autonomic neurotransmission and gastrointestinal transit induced by heat-killed Lactobacillus brevis SBC8803.
- 2015-12-01
- Clinical Trial
- Beneficial Microbes 6(6)
- - Y. Horii
  - Y. Nakakita
  - Y. Misonou
  - T. Nakamura
  - Katsuya Nagai
- PubMed: 26259890
- DOI: 10.3920/BM2015.0031
2 Insights on
- Improved Bowel Movement Frequency
- Improved Gastrointestinal Transit
- Low evidence
- Animal Study
Impact of Kefir Derived Lactobacillus kefiri on the Mucosal Immune Response and Gut Microbiota
- 2015-12-01
- Clinical Trial
- Journal of Immunology Research 2015
- - P. Carasi
  - P. Carasi
  - S. Racedo
  - C. Jacquot
  - D. Romanin
  - M. Serradell
  - M. Urdaci
- PubMed: 25811034
- DOI: 10.1155/2015/361604
8 Insights on
- Low evidence
- Highly Cited
- Animal Study
Consumption of Bifidobacterium animalis subsp. lactis BB-12 in yogurt reduced expression of TLR-2 on peripheral blood-derived monocytes and pro-inflammatory cytokine secretion in young adults
- 2015-11-30
- RCT · n = 30
- European Journal of Nutrition 56(2)
- - Huicui Meng
  - Zhaoyong Ba
  - Yujin Lee
  - Jiayu Peng
  - Junli Lin
  - J. Fleming
  - E. Furumoto
  - R. Roberts
  - P. Kris-Etherton
  - C. Rogers
- PubMed: 26621631
- DOI: 10.1007/s00394-015-1109-5
8 Insights on
- High evidence
- Rigorous Journal
Prevention of Infectious Mastitis by Oral Administration of Lactobacillus salivarius PS2 During Late Pregnancy.
- 2015-11-26
- RCT · n = 108
- Clinical Infectious Diseases 62(5)
- - L. Fernández
  - Nívia Cárdenas
  - Rebeca Arroyo
  - S. Manzano
  - E. Jiménez
  - V. Martín
  - J. M. Rodríguez
- PubMed: 26611780
- DOI: 10.1093/cid/civ974
4 Insights on
- High evidence
- Highly Cited
- Rigorous Journal
The Effectiveness of Lactobacillus Beverages in Controlling Infections among the Residents of an Aged Care Facility: A Randomized Placebo-Controlled Double-Blind Trial
- 2015-11-25
- RCT · n = 72
- Annals of Nutrition and Metabolism 68(1)
- - S. Nagata
  - T. Asahara
  - Chongxin Wang
  - Yumi Suyama
  - O. Chonan
  - K. Takano
  - Masashi Daibou
  - Takuya Takahashi
  - K. Nomoto
  - Y. Yamashiro
- PubMed: 26599038
- DOI: 10.1159/000442305
9 Insights on
- High evidence
Short- and long-term dynamics in the intestinal microbiota following ingestion of Bifidobacterium animalis subsp. lactis GCL2505
- 2015-11-23
- RCT · n = 91
- Bioscience of Microbiota, Food and Health 34(4)
- - Yoshiyuki Tanaka
  - K. Takami
  - Tomohiko Nishijima
  - Ryo Aoki
  - Takashi Mawatari
  - Takayuki Ikeda
- PubMed: 26594607
- DOI: 10.12938/bmfh.2015-001
10 Insights on
- High evidence
- Rigorous Journal
The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity.
- 2015-11-19
- RCT · n = 34
- Clinical interventions in aging 10
- - L Phetcharat
  - K Wongsuphasawat
  - K Winther
- PubMed: 26604725
- DOI: 10.2147/cia.s90092
4 Insights on
- High evidence
Coleus forskohlii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomized Controlled Trial.
- 2015-11-17
- RCT · n = 15
- Nutrients 7(11)
- - Hayley L Loftus
  - Katie J Astell
  - Michael L Mathai
  - Xiao Q Su
- PubMed: 26593941
- DOI: 10.3390/nu7115483
5 Insights on
- High evidence
- Rigorous Journal
Effects of Partial Substitution of Fish Meal by Soybean Meal with or without Heat-Killed Lactobacillus plantarum (LP20) on Growth Performance, Digestibility, and Immune Response of Amberjack, Seriola dumerili Juveniles
- 2015-11-16
- Clinical Trial
- BioMed Research International 2015
- - M. Dawood
  - S. Koshio
  - M. Ishikawa
  - S. Yokoyama
- PubMed: 25705667
- DOI: 10.1155/2015/514196
4 Insights on
- Low evidence
- Highly Cited
- Rigorous Journal
- Animal Study
Mutual Cross-Feeding Interactions between Bifidobacterium longum subsp. longum NCC2705 and Eubacterium rectale ATCC 33656 Explain the Bifidogenic and Butyrogenic Effects of Arabinoxylan Oligosaccharides
- 2015-11-15
- Applied and Environmental Microbiology 81(22)
- - A. Rivière
  - Mérilie Gagnon
  - S. Weckx
  - D. Roy
  - L. De Vuyst
- PubMed: 26319874
- DOI: 10.1128/AEM.02089-15
2 Insights on
- Enhanced Bifidobacterial Growth
- Increased Butyrate Production
- Low evidence
- Highly Cited
Probiotics - the versatile functional food ingredients.
- 2015-11-09
- Review
- Journal of food science and technology 53(2)
- - Gareth Gordon Syngai
  - Ragupathi Gopi
  - Rupjyoti Bharali
  - Sudip Dey
  - G M Alagu Lakshmanan
  - Giasuddin Ahmed
- PubMed: 27162372
- DOI: 10.1007/s13197-015-2011-0
2 Insights on
- Improved Gut Health
- Improved General Health
- Low evidence
Lactobacillus rhamnosus GG Lysate Increases Re-Epithelialization of Keratinocyte Scratch Assays by Promoting Migration
- 2015-11-05
- Scientific Reports 5(1)
- - Walaa Mohammedsaeed
  - S. Cruickshank
  - A. McBain
  - C. O'Neill
- PubMed: 26537246
- DOI: 10.1038/srep16147
1 Insight on
- Improved Skin Re-Epithelialization
- Low evidence
- Highly Cited
The Efficacy and Safety of the Probiotic Bacterium Lactobacillus reuteri DSM 17938 for Infantile Colic: A Meta-Analysis of Randomized Controlled Trials
- 2015-10-28
- Meta-Analysis
- PLOS ONE 10(10)
- - Man Xu
  - Jiao Wang
  - Ning Wang
  - Fei Sun
  - Lin Wang
  - Xiao-hong Liu
  - Vincenzo Lionetti
- PubMed: 26509502
- DOI: 10.1371/journal.pone.0141445
23 Insights on
- High evidence
- Rigorous Journal
Preferential production of G-CSF by a protein-like Lactobacillus rhamnosus GR-1 secretory factor through activating TLR2-dependent signaling events without activation of JNKs
- 2015-10-26
- BMC Microbiology 15(1)
- - S. Meshkibaf
  - J. Fritz
  - M. Gottschalk
  - S. Kim
- PubMed: 26502905
- DOI: 10.1186/s12866-015-0578-2
1 Insight on
- Increased G-CSF Production
- Low evidence
Comparison of active dry yeast (Saccharomyces cerevisiae) and yeast culture for growth performance, carcass traits, meat quality and blood indexes in finishing bulls.
- 2015-10-16
- RCT · n = 45
- Animal Science Journal 87(8)
- - C. Geng
  - L. Ren
  - Zhenming Zhou
  - Ying Chang
  - Qing-xiang Meng
- PubMed: 26472702
- DOI: 10.1111/asj.12522
2 Insights on
- Improved Growth Performance
- Improved Lipid Levels
- Low evidence
- Animal Study
Effects of Bifidobacterium longum BB536 on lipid profile and histopathological changes in hypercholesterolaemic rats.
- 2015-10-15
- RCT · n = 40
- Beneficial Microbes 6(5)
- - S. H. Al-Sheraji
  - I. Amin
  - A. Azlan
  - M. Y. Manap
  - F. Hassan
- PubMed: 26065647
- DOI: 10.3920/BM2014.0032
6 Insights on
- Low evidence
- Animal Study
Red clover for treatment of hot flashes and menopausal symptoms: A systematic review and meta-analysis.
- 2015-10-15
- Meta-Analysis
- Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 36(3)
- - M Ghazanfarpour
  - R Sadeghi
  - R Latifnejad Roudsari
  - I Khorsand
  - T Khadivzadeh
  - B Muoio
- PubMed: 26471215
- DOI: 10.3109/01443615.2015.1049249
6 Insights on
- High evidence
Effect of Lactobacillus johnsonii CRL1647 on different parameters of honeybee colonies and bacterial populations of the bee gut.
- 2015-10-15
- Beneficial Microbes 6(5)
- - M. Audisio
  - D. Sabaté
  - M. R. Benítez-Ahrendts
- PubMed: 25809216
- DOI: 10.3920/BM2014.0155
12 Insights on
- Low evidence
Role of short-term use of L. acidophilus DDS-1 and B. lactis UABLA-12 in acute respiratory infections in children: a randomized controlled trial
- 2015-10-14
- RCT · n = 315
- European Journal of Clinical Nutrition 70(4)
- - SV Gerasimov
  - VA Ivantsiv
  - LM Bobryk
  - OO Tsitsura
  - LP Dedyshin
  - NV Guta
  - BV Yandyo
- PubMed: 26463725
- DOI: 10.1038/ejcn.2015.171
2 Insights on
- Reduced Duration of Acute Respiratory Infection
- Reduced Severity of Acute Respiratory Infection
- High evidence
- Large Human Trial
Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders.
- 2015-10-14
- Review
- Frontiers in cellular neuroscience 9
- - John R Kelly
  - Paul J Kennedy
  - John F Cryan
  - Timothy G Dinan
  - Gerard Clarke
  - Niall P Hyland
- PubMed: 26528128
- DOI: 10.3389/fncel.2015.00392
3 Insights on
- Moderate evidence
- Highly Cited
Cariogram outcome after 90 days of oral treatment with Streptococcus salivarius M18 in children at high risk for dental caries: results of a randomized, controlled study.
- 2015-10-03
- RCT
- Clinical, cosmetic and investigational dentistry 7
- - Francesco Di Pierro
  - Alberto Zanvit
  - Piero Nobili
  - Paolo Risso
  - Carlo Fornaini
- PubMed: 26491371
- DOI: 10.2147/ccide.s93066
2 Insights on
- Reduced Dental Caries
- Improved Cariogram Score
- High evidence
The Consumption of Synbiotic Bread Containing Lactobacillus sporogenes and Inulin Affects Nitric Oxide and Malondialdehyde in Patients with Type 2 Diabetes Mellitus: Randomized, Double-Blind, Placebo-Controlled Trial
- 2015-10-02
- RCT · n = 81
- Journal of the American College of Nutrition 35(6)
- - F. Bahmani
  - Maryam Tajadadi-Ebrahimi
  - F. Kolahdooz
  - Marjan Mazouchi
  - H. Hadaegh
  - Atefeh Jamal
  - Navid Mazroii
  - S. Asemi
  - Z. Asemi
- PubMed: 26430929
- DOI: 10.1080/07315724.2015.1032443
2 Insights on
- Reduced Serum Malondialdehyde Levels
- Increased Plasma Nitric Oxide Levels
- High evidence
- Highly Cited
Daily intake of fermented milk with Lactobacillus casei strain Shirota reduces the incidence and duration of upper respiratory tract infections in healthy middle-aged office workers
- 2015-09-29
- RCT · n = 96
- European Journal of Nutrition 56(1)
- - K. Shida
  - Tadashi Sato
  - R. Iizuka
  - R. Hoshi
  - O. Watanabe
  - Tomoki Igarashi
  - K. Miyazaki
  - M. Nanno
  - F. Ishikawa
- PubMed: 26419583
- DOI: 10.1007/s00394-015-1056-1
7 Insights on
- High evidence
- Highly Cited
- Rigorous Journal
Enhanced butyrate formation by cross-feeding between Faecalibacterium prausnitzii and Bifidobacterium adolescentis.
- 2015-09-28
- FEMS Microbiology Letters 362(21)
- - D. Ríos-Covian
  - M. Gueimonde
  - S. Duncan
  - H. Flint
  - C. G. de los Reyes-Gavilán
- PubMed: 26420851
- DOI: 10.1093/femsle/fnv176
1 Insight on
- Increased Butyrate Production
- Low evidence
- Highly Cited
Gut microbiota and liver diseases.
- 2015-09-18
- Review
- World journal of gastroenterology 21(6)
- - Masami Minemura
  - Yukihiro Shimizu
- PubMed: 25684933
- DOI: 10.3748/wjg.v21.i6.1691
1 Insight on
- Reduced Liver Disease Symptoms
- Moderate evidence
- Highly Cited
Effect of the probiotic strain Bifidobacterium animalis subsp. lactis, BB-12®, on defecation frequency in healthy subjects with low defecation frequency and abdominal discomfort: a randomised, double-blind, placebo-controlled, parallel-group trial.
- 2015-09-18
- RCT · n = 1,248
- The British journal of nutrition 114(10)
- - Dorte Eskesen
  - Lillian Jespersen
  - Birgit Michelsen
  - Peter J Whorwell
  - Stefan Müller-Lissner
  - Cathrine M Morberg
- PubMed: 26382580
- DOI: 10.1017/s0007114515003347
5 Insights on
- High evidence
- Large Human Trial
Effect of the probiotic strain Bifidobacterium animalis subsp. lactis, BB-12®, on defecation frequency in healthy subjects with low defecation frequency and abdominal discomfort: a randomised, double-blind, placebo-controlled, parallel-group trial
- 2015-09-18
- RCT · n = 1,248
- British Journal of Nutrition 114(10)
- - D. Eskesen
  - L. Jespersen
  - B. Michelsen
  - P. Whorwell
  - S. Müller-lissner
  - Cathrine M Morberg
- PubMed: 26382580
- DOI: 10.1017/S0007114515003347
9 Insights on
- High evidence
- Large Human Trial
Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in early childhood
- 2015-09-15
- RCT · n = 109
- Pediatric Research 79(1)
- - T. Taipale
  - K. Pienihäkkinen
  - E. Isolauri
  - J. Jokela
  - E. Söderling
- PubMed: 26372517
- DOI: 10.1038/pr.2015.174
6 Insights on
- High evidence
The vaginal isolate Lactobacillus paracasei LPC-S01 (DSM 26760) is suitable for oral administration
- 2015-09-15
- Clinical Trial
- Frontiers in Microbiology 6
- - S. Balzaretti
  - Valentina Taverniti
  - Greta Rondini
  - Giorgio Marcolegio
  - M. Minuzzo
  - M. C. Remagni
  - W. Fiore
  - S. Arioli
  - S. Guglielmetti
- PubMed: 26441886
- DOI: 10.3389/fmicb.2015.00952
4 Insights on
- Moderate evidence
Bifidobacterium infantis attenuates colitis by regulating T cell subset responses.
- 2015-09-14
- Clinical Trial
- World Journal of Gastroenterology 20(48)
- - L. Zuo
  - Kai-Tao Yuan
  - Li Yu
  - Qing-Hong Meng
  - P. C. Chung
  - Ding-hua Yang
- PubMed: 25561798
- DOI: 10.3748/wjg.v20.i48.18316
4 Insights on
- Low evidence
- Rigorous Journal
- Animal Study