February 2018 Supplement Research Papers

• February 5

  • Antidiabetic (type 2) effects of Lactobacillus G15 and Q14 in rats through regulation of intestinal permeability and microbiota.

    • 2018-02-05
    • Clinical Trial
    • Food & Function 7(9)
    • • Peijun Tian
      • Baolong Li
      • Canxia He
      • Wei Song
      • Aiju Hou
      • Sicong Tian
      • Xinyu Meng
      • Kaikai Li
      • Yujuan Shan

    • PubMed: 27713957
    • DOI: 10.1039/C6FO00831C

    12 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Intestinal Permeability
    • Reduced Inflammation Levels
    • Improved Glucose Tolerance
    • Improved Immunomodulation
    • Reduced Pro-inflammatory Cytokine Levels
    • Enhanced Immune Function
    • Improved Epithelial Barrier Function
    • Reduced Blood HbA1c Levels
    • Reduced IL-6 Levels
    • Reversed Thymic Atrophy
    • Reduced Islet β-Cell Dysfunction

    • Low evidence
    • Highly Cited
    • Animal Study

  • Influence of the addition of Lactobacillus acidophilus La-05, Bifidobacterium animalis subsp. lactis Bb-12 and inulin on the technological, physicochemical, microbiological and sensory features of creamy goat cheese.

    • 2018-02-05
    • Food & function 7(10)
    • • Ilsa C Barbosa
      • Maria E G Oliveira
      • Marta S Madruga
      • Beatriz Gullón
      • Maria T B Pacheco
      • Ana M P Gomes
      • Ana S M Batista
      • Maria M E Pintado
      • Evandro L Souza
      • Rita C R E Queiroga

    • PubMed: 27711907
    • DOI: 10.1039/c6fo00657d

    1 Insight on

    • Increased Conjugated Linoleic Acid Levels

    • Low evidence
    • Rigorous Journal
    • Animal Study
• February 6

  • Beneficial changes in rumen bacterial community profile in sheep and dairy calves as a result of feeding the probiotic Bacillus amyloliquefaciens H57

    • 2018-02-06
    • Journal of Applied Microbiology 124(3)
    • • B. Schofield
      • B. Schofield
      • Nancy Lachner
      • O. Le
      • D. McNeill
      • P. Dart
      • D. Ouwerkerk
      • P. Hugenholtz
      • A. Klieve

    • PubMed: 29314469
    • DOI: 10.1111/jam.13688

    1 Insight on

    • Increased Body Weight

    • Low evidence
• February 8

  • Effects of 28-day Bifidobacterium animalis subsp. lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms in adults with functional constipation: A double-blind, randomized, placebo-controlled, and dose-ranging trial

    • 2018-02-08
    • RCT · n = 228
    • Gut Microbes 9(3)
    • • A. Ibarra
      • Mathilde Latreille-Barbier
      • Y. Donazzolo
      • X. Pelletier
      • A. Ouwehand

    • PubMed: 29227175
    • DOI: 10.1080/19490976.2017.1412908

    22 Insights on

    • Improved Bowel Movement Frequency
    • Reduced Straining
    • Improved Stool Consistency
    • Increased Bowel Movement Frequency
    • Improved Quality of Life
    • Reduced Flatulence
    • Improved Gastrointestinal Tolerance
    • Good Tolerability
    • Increased Bowel Movements
    • Improved Constipation Symptoms
    • Reduced Colonic Transit Time
    • Improved Tolerance
    • Improved Tolerability of Bifidobacterium lactis HN019
    • Improved General Tolerance
    • Few Adverse Effects
    • Improved Rectal Emptying
    • Improved Transit Time
    • Reduced Pain Severity
    • Reduced PAC-SYM Score
    • Improved PAC-QoL Score
    • Reduced Constipation Symptoms
    • Improved Bowel Function Index

    • High evidence
    • Rigorous Journal

  • Complete Genome Sequence and Genomic Characterization of Lactobacillus acidophilus LA1 (11869BP).

    • 2018-02-08
    • Frontiers in pharmacology 9
    • • Won-Hyong Chung
      • Jisu Kang
      • Mi Young Lim
      • Tae-Joong Lim
      • Sanghyun Lim
      • Seong Woon Roh
      • Young-Do Nam

    • PubMed: 29472862
    • DOI: 10.3389/fphar.2018.00083

    1 Insight on

    • Reduced Susceptibility to Infection

    • Low evidence
• February 14

  • Probiotic and anti-inflammatory potential of Lactobacillus rhamnosus 4B15 and Lactobacillus gasseri 4M13 isolated from infant feces

    • 2018-02-14
    • PLOS ONE 13(2)
    • • N. Oh
      • J. Joung
      • J. Lee
      • Younghoon Kim

    • PubMed: 29444150
    • DOI: 10.1371/journal.pone.0192021

    15 Insights on

    • Reduced Total Cholesterol Levels
    • Reduced Pro-Inflammatory Cytokines
    • Increased Antioxidant Activity
    • Reduced α-Glucosidase Activity
    • Reduced Inflammation Levels
    • Reduced Serum Cholesterol Levels
    • Reduced Pro-Inflammatory Mediator Production
    • Improved Antioxidant Activity
    • Enhanced Antioxidant Activity
    • Reduced Nitric Oxide Production
    • Improved Glucose Metabolism
    • Enhanced Antioxidant Levels
    • Reduced Release of Inflammatory Mediators (TNF-α, IL-6, IL-1β, IL-10)
    • Improved Oxidative Stress Levels
    • Reduced Inflammatory Mediators

    • Moderate evidence
    • Highly Cited
    • Rigorous Journal
• February 15

  • Efficacy of Bifidobacterium breve Fermented Milk in Maintaining Remission of Ulcerative Colitis

    • 2018-02-15
    • RCT · n = 195
    • Digestive Diseases and Sciences 63(7)
    • • K. Matsuoka
      • Y. Uemura
      • T. Kanai
      • R. Kunisaki
      • Yasuo Suzuki
      • K. Yokoyama
      • N. Yoshimura
      • T. Hibi

    • PubMed: 29450747
    • DOI: 10.1007/s10620-018-4946-2

    3 Insights on

    • Increased Adverse Events
    • Increased Relapse-Free Survival in Ulcerative Colitis
    • Maintained Remission in Ulcerative Colitis

    • High evidence
    • Highly Cited
    • Rigorous Journal

  • Lactobacillus casei triggers a TLR mediated RACK-1 dependent p38 MAPK pathway in Caenorhabditis elegans to resist Klebsiella pneumoniae infection.

    • 2018-02-15
    • Food & Function 7(7)
    • • A. Kamaladevi
      • K. Balamurugan

    • PubMed: 27338631
    • DOI: 10.1039/c6fo00510a

    5 Insights on

    • Enhanced Resistance to Infections
    • Reduced Helicobacter pylori Colonization
    • Reduced Physiological Impairments
    • Enhanced Resistance to Bacterial Infections
    • Enhanced Host Resistance

    • Low evidence
• February 16

  • Heat-killed and live Lactobacillus reuteri GMNL-263 exhibit similar effects on improving metabolic functions in high-fat diet-induced obese rats.

    • 2018-02-16
    • Clinical Trial
    • Food & Function 7(5)
    • • Feng-Ching Hsieh
      • C. Lan
      • Tsui-Yin Huang
      • Kuan-Wei Chen
      • C. Chai
      • Wan-Tzu Chen
      • Ai-Hui Fang
      • Yi-Hsing Chen
      • Ching-Shuang Wu

    • PubMed: 27163114
    • DOI: 10.1039/c5fo01396h

    23 Insights on

    • Improved Insulin Sensitivity
    • Improved Gut Microbiota
    • Improved Intestinal Barrier Function
    • Improved Blood Glucose Levels
    • Improved Insulin Levels
    • Reduced Inflammation Levels
    • Reduced Serum Glucose Levels
    • Improved Gut Microbiota Balance
    • Reduced Blood Glucose Levels
    • Reduced Insulin Levels
    • Reduced Hepatic Steatosis
    • Reduced Weight Gain
    • Increased Probiotic Bacterial Count
    • Increased Probiotic B. lactis Levels
    • Improved Lipid Levels
    • Reduced Macrophage Infiltration in Adipose Tissue
    • Improved Insulin Resistance
    • Reduced Hepatic Lipogenesis
    • Reduced Hepatic Lipid Synthesis
    • Reduced Lipid Profiles
    • Enhanced Probiotic Bacteria Count
    • Increased Probiotic Levels
    • Improved Serum Glucose Levels

    • Low evidence
    • Animal Study
• February 17

  • Septicemia from Lactobacillus rhamnosus GG, from a Probiotic Enriched Yogurt, in a Patient with Autologous Stem Cell Transplantation

    • 2018-02-17
    • Case Report · n = 1
    • Probiotics and Antimicrobial Proteins 11(1)
    • • S. Koyama
      • H. Fujita
      • T. Shimosato
      • A. Kamijo
      • Yasufumi Ishiyama
      • Eri Yamamoto
      • Yoshimi Ishii
      • Y. Hattori
      • M. Hagihara
      • E. Yamazaki
      • N. Tomita
      • H. Nakajima

    • PubMed: 29455334
    • DOI: 10.1007/s12602-018-9399-6

    3 Insights on

    • Septicemia Incidence
    • Occurrence of Septic Shock
    • Reduced Risk of Infection

    • Low evidence
• February 19

  • Evaluating the Probiotic Potential of Lactobacillus plantarum Strains from Algerian Infant Feces: Towards the Design of Probiotic Starter Cultures Tailored for Developing Countries

    • 2018-02-19
    • Probiotics and Antimicrobial Proteins 11(1)
    • • Chahira Gheziel
      • P. Russo
      • M. Arena
      • G. Spano
      • H. Ouzari
      • O. Kheroua
      • D. Saidi
      • D. Fiocco
      • H. Kaddouri
      • V. Capozzi

    • PubMed: 29460213
    • DOI: 10.1007/s12602-018-9396-9

    1 Insight on

    • Improved Gut Adhesion

    • Low evidence
• February 20

  • Galactomannan from Trigonella foenum‐graecum L. seed: Prebiotic application and its fermentation by the probiotic Bacillus coagulans strain MTCC 5856

    • 2018-02-20
    • Food Science & Nutrition 6(3)
    • • M. Majeed
      • Shaheen Majeed
      • K. Nagabhushanam
      • S. Arumugam
      • Sankaran Natarajan
      • Kirankumar Beede
      • Furqan Ali

    • PubMed: 29876118
    • DOI: 10.1002/fsn3.606

    1 Insight on

    • Reduced Escherichia coli Growth

    • Low evidence

  • Comparison of the effect of lavender and bitter orange on anxiety in postmenopausal women: A triple-blind, randomized, controlled clinical trial.

    • 2018-02-20
    • RCT · n = 52
    • Complementary therapies in clinical practice 31
    • • Azizeh Farshbaf-Khalili
      • Mahin Kamalifard
      • Mahsa Namadian

    • PubMed: 29705445
    • DOI: 10.1016/j.ctcp.2018.02.004

    2 Insights on

    • Reduced Anxiety
    • Reduced Trait Anxiety

    • High evidence

  • Active Lactobacillus rhamnosus LA68 or Lactobacillus plantarum WCFS1 administration positively influences liver fatty acid composition in mice on a HFD regime.

    • 2018-02-20
    • Clinical Trial
    • Food & Function 7(6)
    • • N. Ivanovic
      • R. Minić
      • I. Djuricić
      • Sanja Radojević Škodrić
      • I. Živković
      • S. Sobajic
      • B. Djordjevic

    • PubMed: 27231730
    • DOI: 10.1039/c5fo01432h

    2 Insights on

    • Reduced Body Weight
    • Improved Liver Fatty Acid Composition

    • Low evidence
    • Animal Study

  • Assessment of Efficacy of BLIS-Producing Probiotic K12 for the Prevention of Group A Streptococcus Pharyngitis: a Short Communication

    • 2018-02-20
    • Probiotics and Antimicrobial Proteins 11(1)
    • • F. Di Pierro

    • PubMed: 29464500
    • DOI: 10.1007/s12602-018-9398-7

    2 Insights on

    • Prevention of Streptococcal Pharyngitis
    • Reduced Incidence of Group A Streptococcus Pharyngitis

    • Low evidence
• February 23

  • Rapid assessment of viable but non-culturable Bacillus coagulans MTCC 5856 in commercial formulations using Flow cytometry

    • 2018-02-23
    • PLOS ONE 13(2)
    • • M. Majeed
      • Shaheen Majeed
      • K. Nagabhushanam
      • Ardra Punnapuzha
      • S. Philip
      • Lakshmi A Mundkur

    • PubMed: 29474436
    • DOI: 10.1371/journal.pone.0192836

    1 Insight on

    • Accurate Enumeration of Viable Probiotic Bacteria

    • Low evidence
    • Rigorous Journal
• Undated – 4 supplement studies

  • Efficacy and safety of vaginally administered lyophilized Lactobacillus crispatus IP 174178 in the prevention of bacterial vaginosis recurrence.

    • 2018-02
    • RCT · n = 78
    • Journal of Gynecology Obstetrics and Human Reproduction 47(2)
    • • J. Bohbot
      • Emile Daraï
      • Florence Bretelle
      • G. Brami
      • C. Daniel
      • J. Cardot

    • PubMed: 29196153
    • DOI: 10.1016/j.jogoh.2017.11.005

    2 Insights on

    • Reduced Recurrence of Bacterial Vaginosis
    • Increased Time to Bacterial Vaginosis Recurrence

    • High evidence

  • Effects of various feeding patterns of Bacillus coagulans on growth performance, antioxidant response and Nrf2‐Keap1 signaling pathway in juvenile gibel carp (Carassius auratus gibelio)

    • 2018-02
    • Clinical Trial
    • Fish & Shellfish Immunology 73
    • • Ye-bing Yu
      • Changhai Wang
      • Ai-ming Wang
      • Wenping Yang
      • F. Lv
      • Fei Liu
      • Bo Liu
      • Cunxin Sun

    • PubMed: 29196031
    • DOI: 10.1016/j.fsi.2017.11.050

    3 Insights on

    • Improved Growth Performance
    • Enhanced Antioxidant Response
    • Reduced Oxidative Stress

    • Low evidence
    • Animal Study

  • l-Carnosine As an Adjunctive Therapy to Risperidone in Children with Autistic Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial.

    • 2018-02
    • RCT
    • Journal of child and adolescent psychopharmacology 28(1)
    • • Reihaneh Hajizadeh-Zaker
      • Alireza Ghajar
      • Bita Mesgarpour
      • Mohsen Afarideh
      • Mohammad-Reza Mohammadi
      • Shahin Akhondzadeh

    • PubMed: 29027815
    • DOI: 10.1089/cap.2017.0026

    5 Insights on

    • Reduced Hyperactivity
    • Reduced Irritability
    • Reduced Lethargy
    • Reduced Stereotypic Behavior
    • Reduced Inappropriate Speech

    • High evidence

  • Brewer’s yeast is a potent inducer of fever, sickness behavior and inflammation within the brain

    • 2018-02
    • Clinical Trial · n = 20
    • Brain, Behavior, and Immunity 68
    • • R. Dangarembizi
      • K. Erlwanger
      • C. Rummel
      • J. Roth
      • M. Madziva
      • L. Harden

    • PubMed: 29074357
    • DOI: 10.1016/j.bbi.2017.10.019

    5 Insights on

    • Increased Energy Levels
    • Reduced Fever Incidence
    • Reduced Appetite
    • Reduced Body Mass Stunting
    • Increased Hypothalamic Expression of Pro-inflammatory Markers

    • Low evidence
    • Rigorous Journal
    • Animal Study