March 2020 Supplement Research Papers

• March 2

  • In Vitro Probiotic Potential and Safety Evaluation (Hemolytic, Cytotoxic Activity) of Bifidobacterium Strains Isolated from Raw Camel Milk

    • 2020-03-02
    • Microorganisms 8(3)
    • • I. Yasmin
      • M. Saeed
      • W. A. Khan
      • A. Khaliq
      • M. F. J. Chughtai
      • R. Iqbal
      • Saima Tehseen
      • S. Naz
      • Atif Liaqat
      • T. Mehmood
      • S. Ahsan
      • Saira Tanweer

    • PubMed: 32131456
    • DOI: 10.3390/microorganisms8030354

    4 Insights on

    • Reduced Intestinal Cell Adhesion
    • Increased Antioxidant Activity
    • Improved Cholesterol Levels
    • Increased Antimicrobial Resistance

    • Moderate evidence
    • Highly Cited
    • Rigorous Journal

  • Dairy pastoralism sustained eastern Eurasian steppe populations for 5,000 years.

    • 2020-03-02
    • Observational
    • Nature ecology & evolution 4(3)
    • • Shevan Wilkin
      • Alicia Ventresca Miller
      • William T T Taylor
      • Bryan K Miller
      • Richard W Hagan
      • Madeleine Bleasdale
      • Ashley Scott
      • Sumiya Gankhuyg
      • Abigail Ramsøe
      • S Uliziibayar
      • Christian Trachsel
      • Paolo Nanni
      • Jonas Grossmann
      • Ludovic Orlando
      • Mark Horton
      • Philipp W Stockhammer
      • Erdene Myagmar
      • Nicole Boivin
      • Christina Warinner
      • Jessica Hendy

    • PubMed: 32127685
    • DOI: 10.1038/s41559-020-1120-y

    2 Insights on

    • Improved Survival
    • Earlier Evidence of Dairy Consumption

    • Low evidence
• March 3

  • Benefit of Dietary Supplementation with Bacillus subtilis BYS2 on Growth Performance, Immune Response, and Disease Resistance of Broilers

    • 2020-03-03
    • Probiotics and Antimicrobial Proteins 12(4)
    • • Y. Dong
      • Rong Li
      • Yu Liu
      • L. Ma
      • Jihua Zha
      • X. Qiao
      • T. Chai
      • Bo Wu

    • PubMed: 32128666
    • DOI: 10.1007/s12602-020-09643-w

    6 Insights on

    • Improved Growth Performance
    • Enhanced Disease Resistance
    • Improved Innate Immunity
    • Improved Immunological Indices
    • Elevated Serum Immunoglobulin Levels
    • Improved Intestinal Structure

    • Low evidence
• March 7

  • Bacillus coagulans SANK 70258 suppresses Enterobacteriaceae in the microbiota of ulcerative colitis in vitro and enhances butyrogenesis in healthy microbiota

    • 2020-03-07
    • Applied Microbiology and Biotechnology 104(9)
    • • K. Sasaki
      • D. Sasaki
      • J. Inoue
      • N. Hoshi
      • Takayuki Maeda
      • Ryouichi Yamada
      • A. Kondo

    • PubMed: 32146494
    • DOI: 10.1007/s00253-020-10506-1

    8 Insights on

    • Increased Butyrate Levels
    • Reduced Abundance of Enterobacteriaceae Species
    • Increased Butyrate Production in Healthy Subjects
    • Increased Butyrate Production
    • Reduced Colonic Enterobacteriaceae Species
    • Improved Intestinal Microenvironment in Ulcerative Colitis
    • Suppressed Enterobacteriaceae Levels
    • Improved Colonic Microenvironment

    • Low evidence
• March 9

  • Application of Bacillus coagulans in Animal Husbandry and Its Underlying Mechanisms

    • 2020-03-09
    • Review
    • Animals 10(3)
    • • Yuanhao Zhou
      • Zihan Zeng
      • Yibin Xu
      • Jiafu Ying
      • Baikui Wang
      • M. Majeed
      • Shaheen Majeed
      • A. Pande
      • Wei-fen Li

    • PubMed: 32182789
    • DOI: 10.3390/ani10030454

    6 Insights on

    • Improved Immune Function
    • Improved Gut Microbiota Balance
    • Regulated Intestinal Microbiota Balance
    • Enhanced Immunity
    • Improved Intestinal Microbiota Balance
    • Increased Industrial Property Risk

    • Moderate evidence
    • Rigorous Journal
• March 13

  • Pasteurized Akkermansia muciniphila increases whole-body energy expenditure and fecal energy excretion in diet-induced obese mice

    • 2020-03-13
    • Clinical Trial
    • Gut Microbes 11(5)
    • • C. Depommier
      • M. Van Hul
      • A. Everard
      • N. Delzenne
      • W. D. de Vos
      • Patrice D Cani

    • PubMed: 32167023
    • DOI: 10.1080/19490976.2020.1737307

    3 Insights on

    • Reduced Body Weight
    • Increased Energy Expenditure
    • Increased Fecal Energy Excretion

    • Low evidence
    • Highly Cited
    • Rigorous Journal
    • Animal Study

  • Production of multiple bacteriocins, including the novel bacteriocin gassericin M, by Lactobacillus gasseri LM19, a strain isolated from human milk

    • 2020-03-13
    • Applied Microbiology and Biotechnology 104(9)
    • • Enriqueta Garcia-Gutierrez
      • P. O’Connor
      • I. Colquhoun
      • Natalia M. Vior
      • J. M. Rodríguez
      • M. Mayer
      • P. Cotter
      • A. Narbad

    • PubMed: 32170384
    • DOI: 10.1007/s00253-020-10493-3

    1 Insight on

    • Improved Gut Microbiota Homeostasis

    • Low evidence
• March 14

  • Lactobacillus salivarius A3iob Reduces the Incidence of Varroa destructor and Nosema Spp. in Commercial Apiaries Located in the Northwest of Argentina

    • 2020-03-14
    • Clinical Trial
    • Probiotics and Antimicrobial Proteins 12(4)
    • • M. Tejerina
      • M. R. Benítez-Ahrendts
      • M. Audisio

    • PubMed: 32172463
    • DOI: 10.1007/s12602-020-09638-7

    1 Insight on

    • Reduced Varroa Incidence

    • Low evidence
    • Animal Study
• March 16

  • Herbal formulation "turmeric extract, black pepper, and ginger" versus Naproxen for chronic knee osteoarthritis: A randomized, double-blind, controlled clinical trial.

    • 2020-03-16
    • RCT
    • Phytotherapy research : PTR 34(8)
    • • Motahar Heidari-Beni
      • Amir R Moravejolahkami
      • Pegah Gorgian
      • Gholamreza Askari
      • Mohammad J Tarrahi
      • Nimah Bahreini-Esfahani

    • PubMed: 32180294
    • DOI: 10.1002/ptr.6671

    1 Insight on

    • Reduced Prostaglandin E2 Level

    • High evidence

  • Effects of probiotic Lactobacillus acidophilus D2/CSL (CECT 4529) on the nutritional and health status of boxer dogs

    • 2020-03-16
    • RCT · n = 40
    • Veterinary Record 187(4)
    • • S. Marelli
      • E. Fusi
      • A. Giardini
      • P. Martino
      • M. Polli
      • N. Bruni
      • R. Rizzi

    • PubMed: 32179577
    • DOI: 10.1136/vr.105434

    3 Insights on

    • Reduced Escherichia coli Counts
    • Improved Stool Quality
    • Improved Body Condition Score

    • Low evidence
    • Animal Study
• March 17

  • A Pilot Randomized Control Trial With the Probiotic Strain Lactobacillus rhamnosus GG (LGG) in ADHD: Children and Adolescents Report Better Health-Related Quality of Life

    • 2020-03-17
    • RCT · n = 35
    • Frontiers in Psychiatry 11
    • • H. Kumperščak
      • A. Gricar
      • I. Ülen
      • D. Mičetić-Turk

    • PubMed: 32256407
    • DOI: 10.3389/fpsyt.2020.00181

    2 Insights on

    • Improved Quality of Life
    • Improved Health-related Quality of Life

    • High evidence

  • Bifidobacterium longum subsp. infantis ATCC 15697 and Goat Milk Oligosaccharides Show Synergism In Vitro as Anti-Infectives against Campylobacter jejuni

    • 2020-03-17
    • Foods 9(3)
    • • Erinn M Quinn
      • H. Slattery
      • D. Walsh
      • L. Joshi
      • R. Hickey

    • PubMed: 32192119
    • DOI: 10.3390/foods9030348

    9 Insights on

    • Enhanced Probiotic Growth
    • Reduced Pathogen Adherence
    • Enhanced Beneficial Metabolite Production
    • Reduced Pathogen Adhesion
    • Reduced Adherence of Campylobacter jejuni to Intestinal Cells
    • Increased Production of Bioactive Metabolites
    • Reduced Pathogen Association
    • Enhanced Bacterial Growth
    • Enhanced Growth of Beneficial Gut Bacteria

    • Low evidence
    • Rigorous Journal
• March 18

  • Competitive Exclusion Is a Major Bioprotective Mechanism of Lactobacilli against Fungal Spoilage in Fermented Milk Products.

    • 2020-03-18
    • Applied and environmental microbiology 86(7)
    • • Solvej Siedler
      • Martin Holm Rau
      • Susanne Bidstrup
      • Justin M Vento
      • Stina Dissing Aunsbjerg
      • Elleke F Bosma
      • Laura M McNair
      • Chase L Beisel
      • Ana Rute Neves

    • PubMed: 32005739
    • DOI: 10.1128/aem.02312-19

    1 Insight on

    • Reduced Microbial Spoilage

    • Low evidence
    • Rigorous Journal
• March 19

  • Dietary Postbiotic Lactobacillus plantarum Improves Serum and Ruminal Antioxidant Activity and Upregulates Hepatic Antioxidant Enzymes and Ruminal Barrier Function in Post-Weaning Lambs

    • 2020-03-19
    • Antioxidants 9(3)
    • • Wan Ibrahim Izuddin
      • A. M. Humam
      • T. Loh
      • H. Foo
      • A. Samsudin

    • PubMed: 32204511
    • DOI: 10.3390/antiox9030250

    5 Insights on

    • Reduced Lipid Peroxidation
    • Improved Antioxidant Activity
    • Enhanced Antioxidant Activity
    • Increased Hepatic Antioxidant Enzyme Activity
    • Increased Hepatic Antioxidant Enzyme Levels

    • Low evidence
    • Rigorous Journal
• March 22

  • Lactobacillus Acidophilus/Bifidobacterium Infantis Probiotics Are Beneficial to Extremely Low Gestational Age Infants Fed Human Milk

    • 2020-03-22
    • Observational · n = 7,516
    • Nutrients 12(3)
    • • Ingmar Fortmann
      • J. Marissen
      • Bastian Siller
      • J. Spiegler
      • Alexander Humberg
      • Kathrin Hanke
      • Kirstin Faust
      • Julia Pagel
      • Leila Eyvazzadeh
      • Kim Brenner
      • C. Roll
      • S. Pirr
      • D. Viemann
      • D. Stavropoulou
      • P. Henneke
      • Birte Tröger
      • Thorsten Körner
      • A. Stein
      • Christoph Derouet
      • M. Zemlin
      • C. Wieg
      • J. Rupp
      • E. Herting
      • W. Göpel
      • C. Härtel

    • PubMed: 32235769
    • DOI: 10.3390/nu12030850

    9 Insights on

    • Improved Growth Rate
    • Reduced Incidence of Clinical Sepsis
    • Improved Weight Gain
    • Improved Daily Weight Gain
    • Reduced Sepsis Incidence
    • Improved Growth
    • Improved Growth in Human Milk-fed Infants
    • Improved Growth in Infants
    • Reduced Clinical Sepsis

    • High evidence
• March 25

  • Bifidobacterium animalis subsp. lactis 420 for Metabolic Health: Review of the Research

    • 2020-03-25
    • Review
    • Nutrients 12(4)
    • • Henna-Maria Uusitupa
      • Pia Rasinkangas
      • M. Lehtinen
      • S. Mäkelä
      • K. Airaksinen
      • H. Anglenius
      • A. Ouwehand
      • J. Maukonen

    • PubMed: 32218248
    • DOI: 10.3390/nu12040892

    4 Insights on

    • Improved Weight Management
    • Reduced Weight Gain
    • Improved Epithelial Integrity
    • Reduced Inflammatory Processes

    • High evidence
• March 26

  • Probiotic Mixture of Lactobacillus plantarum Strains Improves Lipid Metabolism and Gut Microbiota Structure in High Fat Diet-Fed Mice

    • 2020-03-26
    • RCT · n = 3
    • Frontiers in Microbiology 11
    • • Huizhen Li
      • Fei Liu
      • Jingjing Lu
      • Jialu Shi
      • Jiaqi Guan
      • Fenfen Yan
      • Bailiang Li
      • G. Huo

    • PubMed: 32273874
    • DOI: 10.3389/fmicb.2020.00512

    13 Insights on

    • Increased Short-Chain Fatty Acid Levels
    • Reduced Body Weight
    • Reduced Hepatic Oxidative Stress
    • Reduced Obesity
    • Reduced Blood Lipid Levels
    • Improved Liver Function
    • Reduced Liver Lipid Accumulation
    • Improved Lipid Metabolism
    • Improved Gut Microbiota Structure
    • Enhanced Lipid Metabolism in Adipose Tissue
    • Regulated Lipid Metabolism in Epididymal Fat Pads
    • Reduced Hepatic Lipid Accumulation
    • Reduced Obesity Indicators

    • Low evidence
    • Highly Cited
    • Animal Study

  • Dairy Propionibacterium freudenreichii ameliorates acute colitis by stimulating MUC2 expression in intestinal goblet cell in a DSS-induced colitis rat model

    • 2020-03-26
    • Clinical Trial
    • Scientific Reports 10(1)
    • • Seongho Ma
      • Jiah Yeom
      • Y. Lim

    • PubMed: 32218552
    • DOI: 10.1038/s41598-020-62497-8

    1 Insight on

    • Increased Fecal Propionic Acid Levels

    • Low evidence
    • Rigorous Journal
    • Animal Study
• March 27

  • Treatment with Anaerobutyricum soehngenii: a pilot study of safety and dose–response effects on glucose metabolism in human subjects with metabolic syndrome

    • 2020-03-27
    • Clinical Trial · n = 24
    • npj Biofilms and Microbiomes 6(1)
    • • P. W. Gilijamse
      • Annick V. Hartstra
      • E. Levin
      • Koen Wortelboer
      • M. Serlie
      • M. Ackermans
      • H. Herrema
      • A. Nederveen
      • S. Imangaliyev
      • S. Aalvink
      • Morton Sommer
      • H. Levels
      • E. Stroes
      • A. Groen
      • Marleen Kemper
      • W. D. de Vos
      • M. Nieuwdorp
      • A. Prodan

    • PubMed: 32221294
    • DOI: 10.1038/s41522-020-0127-0

    2 Insights on

    • Improved Insulin Sensitivity
    • Altered Bile Acid Metabolism

    • High evidence
    • Rigorous Journal

  • The Possibility of Suppression of Increased Postprandial Blood Glucose Levels by Gamma-Polyglutamic Acid-Rich Natto in the Early Phase after Eating: A Randomized Crossover Pilot Study

    • 2020-03-27
    • RCT
    • Nutrients 12(4)
    • • R. Araki
      • K. Fujie
      • Nanako Yuine
      • Yuta Watabe
      • K. Maruo
      • Hiroaki Suzuki
      • Koichi Hashimoto

    • PubMed: 32230729
    • DOI: 10.3390/nu12040915

    1 Insight on

    • Reduced Postprandial Glucose Levels

    • High evidence
• March 29

  • Bifidobacterium breve UCC2003 Exopolysaccharide Modulates the Early Life Microbiota by Acting as a Potential Dietary Substrate

    • 2020-03-29
    • Nutrients 12(4)
    • • Deborah Püngel
      • A. Treveil
      • M. Dalby
      • Shabhonam Caim
      • I. Colquhoun
      • C. Booth
      • Jennifer Ketskemety
      • T. Korcsmáros
      • D. van Sinderen
      • Melissa A. E. Lawson
      • L. Hall

    • PubMed: 32235410
    • DOI: 10.3390/nu12040948

    1 Insight on

    • Increased Short-Chain Fatty Acid Production

    • Moderate evidence

  • The Effect of Streptococcus salivarius K12 on Halitosis: a Double-Blind, Randomized, Placebo-Controlled Trial

    • 2020-03-29
    • RCT · n = 28
    • Probiotics and Antimicrobial Proteins 12(4)
    • • Lu He
      • Hongjiang Yang
      • Ziyuan Chen
      • X. Ouyang

    • PubMed: 32227309
    • DOI: 10.1007/s12602-020-09646-7

    4 Insights on

    • Improved Oral Health (Reduced Tongue Coating)
    • Reduced Halitosis
    • Reduced Tongue Coating Score
    • No Significant Difference Compared to Placebo

    • High evidence
• March 30

  • Dietary supplementation with Lactobacillus acidophilus enhanced the growth, gut morphometry, antioxidant capacity, and the immune response in juveniles of the common carp, Cyprinus carpio

    • 2020-03-30
    • RCT · n = 240
    • Fish Physiology and Biochemistry 46(4)
    • • I. Adeshina
      • M. I. Abubakar
      • Bunmi Elizabeth Ajala

    • PubMed: 32232615
    • DOI: 10.1007/s10695-020-00796-7

    6 Insights on

    • Improved Immune Response
    • Improved Growth Performance
    • Improved Antioxidant Capacity
    • Modulated Immune Response
    • Enhanced Intestinal Morphometry
    • Improved Ileal Histomorphometry

    • Low evidence
    • Animal Study
• Undated – 11 supplement studies

  • Lactobacillus paracasei-derived extracellular vesicles attenuate the intestinal inflammatory response by augmenting the endoplasmic reticulum stress pathway

    • 2020-03
    • Clinical Trial
    • Experimental & Molecular Medicine 52(3)
    • • J. Choi
      • C. Moon
      • Tae-Seop Shin
      • Eun Kyoung Kim
      • Andrea McDowell
      • Min-Kyung Jo
      • Y. Joo
      • Seong-Eun Kim
      • Hye-Kyung Jung
      • K. Shim
      • S. Jung
      • Yoon-Keun Kim

    • PubMed: 32123288
    • DOI: 10.1038/s12276-019-0359-3

    15 Insights on

    • Increased Anti-Inflammatory Cytokine Levels
    • Reduced Pro-Inflammatory Cytokines
    • Reduced Inflammatory Response
    • Reduced Colitis Symptoms
    • Reduced Intestinal Inflammation
    • Reduced Inflammation Levels
    • Improved Colitis Symptoms
    • Reduced LPS-Induced Inflammation
    • Reduced Inflammatory Protein Activation
    • Reduced Weight Loss
    • Enhanced Endoplasmic Reticulum Stress Response
    • Protection Against Colitis
    • Enhanced Colorectal Homeostasis
    • Maintained Colorectal Homeostasis
    • Increased ER Stress-Associated Proteins

    • Low evidence
    • Highly Cited
    • Rigorous Journal
    • Animal Study

  • Probiotic Properties of Lactobacillus brevis KU200019 and Synergistic Activity with Fructooligosaccharides in Antagonistic Activity against Foodborne Pathogens

    • 2020-03
    • Food Science of Animal Resources 40(2)
    • • K. M. G. M. M. Kariyawasam
      • Seo-Jin Yang
      • N. Lee
      • H. Paik

    • PubMed: 32161924
    • DOI: 10.5851/kosfa.2020.e15

    9 Insights on

    • Increased Lactic Acid Bacteria Levels
    • Increased Antioxidant Activity
    • Enhanced Gastric Viability
    • Enhanced Viability in Bile Conditions
    • Improved Viability of Lactic Acid Bacteria
    • Improved Digestive Viability
    • Improved Antioxidant Activity
    • Enhanced Antioxidant Activity
    • Increased Probiotic Potential

    • Low evidence

  • Effect of Lactobacillus Plantarum Containing Probiotics on Blood Pressure: A systematic review and meta-analysis.

    • 2020-03
    • Meta-Analysis
    • Pharmacological Research 153
    • • Anne-Mary Lewis-Mikhael
      • Amirhossein Davoodvandi
      • S. Jafarnejad

    • PubMed: 31987993
    • DOI: 10.1016/j.phrs.2020.104663

    3 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Systolic Blood Pressure
    • Reduced Blood Pressure

    • High evidence
    • Rigorous Journal

  • Natto Intake is Inversely Associated with Osteoporotic Fracture Risk in Postmenopausal Japanese Women.

    • 2020-03
    • The Journal of Nutrition 150(3)
    • • A. Kojima
      • S. Ikehara
      • K. Kamiya
      • E. Kajita
      • Yuho Sato
      • K. Kouda
      • J. Tamaki
      • S. Kagamimori
      • M. Iki

    • PubMed: 31825069
    • DOI: 10.1093/jn/nxz292

    1 Insight on

    • Reduced Risk of Osteoporotic Fractures

    • Moderate evidence

  • Exopolysaccharides of Bacillus amyloliquefaciens modulate glycemic level in mice and promote glucose uptake of cells through the activation of Akt.

    • 2020-03
    • Clinical Trial
    • International Journal of Biological Macromolecules 146
    • • Yo-Chia Chen
      • Shen-Da Huang
      • Jing-Hong Tu
      • Jyun-Sian Yu
      • Annisa Oktafianti Nurlatifah
      • Wen‐Chin Chiu
      • Yu-Han Su
      • Hsuan-Lun Chang
      • Diwyacitta Antya Putri
      • Hsueh-Ling Cheng

    • PubMed: 31887379
    • DOI: 10.1016/j.ijbiomac.2019.12.217

    3 Insights on

    • Improved Blood Glucose Levels
    • Enhanced GLP-1 Secretion
    • Increased Glucose Uptake by Cells

    • Low evidence
    • Animal Study

  • Selenium-enriched Bifidobacterium longum protected alcohol and high fat diet induced hepatic injury in mice.

    • 2020-03
    • Clinical Trial
    • Chinese Journal of Natural Medicines 18(3)
    • • H. Yi
      • Xiaoxiao Zhu
      • Xiao-Li Huang
      • Yupei Lai
      • Yue Tang

    • PubMed: 32245586
    • DOI: 10.1016/s1875-5364(20)30018-2

    7 Insights on

    • Reduced Hepatic Oxidative Stress
    • Improved Lipid Metabolism
    • Improved Lipid Profile
    • Reduced Hepatic Fat Accumulation
    • Regulated Lipid Metabolism
    • Enhanced Superoxide Dismutase Activity
    • Reduced Hepatocyte Oxidative Stress

    • Low evidence
    • Animal Study

  • Studies on characteristics and anti-diabetic and -nephritic effects of polysaccharides isolated from Paecilomyces hepiali fermentation mycelium in db/db mice.

    • 2020-03
    • Clinical Trial
    • Carbohydrate Polymers 232
    • • Wenji Hu
      • Juan Wang
      • Weiying Guo
      • Yange Liu
      • Z. Guo
      • Y. Miao
      • Di Wang

    • PubMed: 31952583
    • DOI: 10.1016/j.carbpol.2019.115766

    5 Insights on

    • Improved Blood Glucose Levels
    • Reduced Blood Lipid Levels
    • Improved Diabetic Nephropathy
    • Improved Blood Lipid Profile
    • Improved Glycemia

    • Low evidence
    • Animal Study

  • Effects of dietary Pediococcus acidilactici GY2 single or combined with Saccharomyces cerevisiae or/and β-glucan on the growth, innate immunity response and disease resistance of Macrobrachium rosenbergii.

    • 2020-03
    • RCT · n = 5
    • Fish & Shellfish Immunology 98
    • • Shuyan Miao
      • B. Han
      • Chenze Zhao
      • Juntao Hu
      • Jinyu Zhu
      • Xin Zhang
      • Longsheng Sun

    • PubMed: 31857226
    • DOI: 10.1016/j.fsi.2019.12.038

    12 Insights on

    • Improved Growth Performance
    • Improved Feed Utilization
    • Enhanced Digestive Enzyme Activity
    • Increased Total Hemocyte Counts
    • Reduced Cumulative Mortality
    • Increased Respiratory Burst Activity
    • Increased Protease Activity
    • Increased Lipase Activity
    • Improved Phagocytic Activity
    • Increased Phagocytic Index
    • Reduced Mortality Rate During Pathogen Challenge
    • Improved Lipase Activity

    • Low evidence
    • Animal Study

  • Metabolic activity of Bacillus coagulans R11 and the health benefits of and potential pathogen inhibition by this species in the intestines of laying hens under lead exposure.

    • 2020-03
    • Clinical Trial
    • Science of The Total Environment 709
    • • Sicheng Xing
      • J. Mi
      • Jing-Yuan Chen
      • Jiaxin Hu
      • Xin-Di Liao

    • PubMed: 31881475
    • DOI: 10.1016/j.scitotenv.2019.134507

    4 Insights on

    • Reduced Potential Pathogenic Bacteria
    • Reduced Pathogen Growth
    • Reduced Oxidative Damage
    • Maintained Healthy Gut Environment

    • Low evidence
    • Animal Study

  • Effect of vitamin K1 on survival of patients with chronic liver failure: A retrospective cohort study.

    • 2020-03
    • Observational · n = 80
    • Medicine 99(13)
    • • Zhuang Xiong
      • Yangyang Liu
      • Tianying Chang
      • Xiaohao Xu
      • Shaokai Huo
      • Houbo Deng
      • Tiejun Liu
      • Yan Leng

    • PubMed: 32221088
    • DOI: 10.1097/md.0000000000019619

    2 Insights on

    • Reduced Mortality
    • Reduced International Normalized Ratio

    • Moderate evidence

  • Orodispersible lozenges containing a combination of Lactobacillus reuteri DSM 17938 and Lactobacillus reuteri ATCC PTA 5289 and normal gum function: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    • 2020-03
    • EFSA Journal 18(3)
    • • D. Turck
      • J. Castenmiller
      • S. de Henauw
      • Karen Ildico Hirsch‐Ernst
      • J. Kearney
      • H. Knutsen
      • A. Maciuk
      • I. Mangelsdorf
      • H. Mcardle
      • A. Naska
      • C. Peláez
      • K. Pentieva
      • F. Thies
      • S. Tsabouri
      • M. Vinceti
      • J. Bresson
      • Yolanda Sanz
      • A. Siani

    • PubMed: 32874242
    • DOI: 10.2903/j.efsa.2020.6004

    3 Insights on

    • Improved Oral Health
    • Improved Gum Function
    • Maintained Normal Gum Function

    • Low evidence