Acidophilus milk products: a review of potential benefits to consumers.
- 1989-10
- Review
- Journal of Dairy Science 72(10)
- S. Gilliland
- PubMed: 2513349
- DOI: 10.3168/JDS.S0022-0302(89)79389-9
7 Insights on
- Moderate evidence
- Highly Cited
Supplement Research Feed
The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.
Prevention of antibiotic-associated diarrhea by Saccharomyces boulardii: a prospective study.
- 1989-04
- RCT · n = 180
- Gastroenterology 96(4)
- C. Surawicz
- G. Elmer
- P. Speelman
- LynneV. McFarland
- J. Chinn
- G. Belle
- PubMed: 2494098
- DOI: 10.1016/0016-5085(89)91613-2
4 Insights on- High evidence
- Highly Cited
Antitumor activity of Lactobacillus casei (LC 9018) against experimental mouse bladder tumor (MBT-2).
- 1986-09
- Clinical Trial
- Journal of Urology 136(3)
- Michio Asano
- Eiichi Karasawa
- Tomoyuki Takayama
- PubMed: 3090281
- DOI: 10.1016/S0022-5347(17)45035-X
- Low evidence
- Animal Study
Effect of perorally administered lactobacilli on macrophage activation in mice
- 1986-08
- Clinical Trial
- Infection and Immunity 53(2)
- G. Perdigón
- Maria Elena Nader
- De
- Macias
- '. S. Alvarez
- '. G. Oliver
- Aida A. Pesce
- Ruiz Holgado
- PubMed: 3733223
- DOI: 10.1128/iai.53.2.404-410.1986
- Low evidence
- Highly Cited
- Animal Study
Assimilation of cholesterol by Lactobacillus acidophilus
- 1985-02
- Clinical Trial
- Applied and Environmental Microbiology 49(2)
- S. Gilliland
- C. R. Nelson
- C. Maxwell
- PubMed: 3920964
- DOI: 10.1128/aem.49.2.377-381.1985
- Low evidence
- Highly Cited
- Animal Study
Importance of bile tolerance of Lactobacillus acidophilus used as a dietary adjunct.
- 1984-12
- Journal of Dairy Science 67(12)
- S. Gilliland
- T. E. Staley
- L. Bush
- PubMed: 6442304
- DOI: 10.3168/JDS.S0022-0302(84)81670-7
2 Insights on- Low evidence
- Highly Cited
A comparison of the effect of diets containing beef protein and plant proteins on blood lipids of healthy young men.
- 1984-11
- RCT
- The American journal of clinical nutrition 40(5)
- S L Wiebe
- V M Bruce
- B E McDonald
- PubMed: 6496393
- DOI: 10.1093/ajcn/40.5.982
3 Insights on- High evidence
The effect of milk and lactobacillus feeding on human intestinal bacterial enzyme activity.
- 1984-05
- The American Journal of Clinical Nutrition 39(5)
- B. Goldin
- S. Gorbach
- PubMed: 6424430
- DOI: 10.1093/AJCN/39.5.756
- Low evidence
- Highly Cited
Lactobacillus acidophilus as a dietary adjunct for milk to aid lactose digestion in humans.
- 1983-05
- Clinical Trial · n = 6
- Journal of Dairy Science 66(5)
- H. Kim
- S. Gilliland
- PubMed: 6409948
- DOI: 10.3168/JDS.S0022-0302(83)81887-6
5 Insights on- High evidence
- Highly Cited
Mechanism for nonspecific immunity of Listeria monocytogenes in rats mediated by platelets and the clotting system.
- 1981-08
- Infection and immunity 33(2)
- W A Davies
- V P Ackerman
- D S Nelson
- PubMed: 6792078
- DOI: 10.1128/iai.33.2.477-481.1981
- Low evidence
- Animal Study
Effect of diet and Lactobacillus acidophilus supplements on human fecal bacterial enzymes.
- 1980-02
- Clinical Trial
- JNCI: Journal of the National Cancer Institute 64(2)
- B. Goldin
- L. Swenson
- J. Dwyer
- M. Sexton
- S. Gorbach
- PubMed: 6766508
- DOI: 10.1093/JNCI/64.2.255
3 Insights on- High evidence
- Highly Cited
Aluminum in the environment and human health.
- 1974-08
- Review
- Environmental health perspectives 8
- J R Sorenson
- I R Campbell
- L B Tepper
- R D Lingg
- PubMed: 4470920
- DOI: 10.1289/ehp.7483
- Low evidence
Enhancement of Resistance to Infectious Diseases by Oral Administration of Brewer's Yeast
- 1974-05
- Clinical Trial
- Infection and Immunity 9(5)
- Y. Sinai
- A. Kaplun
- Y. Hai
- B. Halperin
- PubMed: 4132909
- DOI: 10.1128/iai.9.5.781-787.1974
- Low evidence
- Animal Study
Daily mango (Mangifera indica L.) consumption supplemented with probiotics differentially modulates inflammation and cognitive function in individuals with overweight or obesity: a placebo-controlled, double-blind, and randomized trial.
- 2026
- RCT
- Food & function 17(2)
- Hyemee Kim
- Kevin B Kiefer
- Shannon E Schmidt-Combest
- Giuliana Noratto
- Shirley Arbizu
- Maria Joselyn Castellon Chicas
- Nicos C Georghiades
- Steven E Riechman
- Colin D Kay
- Rodrigo San-Cristobal
- Stephen T Talcott
- Susanne U Mertens-Talcott
- PubMed: 41410576
- DOI: 10.1039/d5fo01687h
- High evidence
- Rigorous Journal
Effects of fish oil supplementation on biomarkers of vascular endothelial function in middle-aged and older adults: a randomized controlled trial.
- 2026
- RCT · n = 240
- Food & function 17(3)
- Chunxia Quan
- Wei Tang
- Yuting Qin
- Zhaoyang Nian
- Zhongxia Li
- Limei Mao
- PubMed: 41568898
- DOI: 10.1039/d5fo04037j
6 Insights on- High evidence
- Large Human Trial
- Rigorous Journal
The relationships among nutrition, body composition, muscle strength and physical performance in patients with acromegaly.
- 2026
- Observational · n = 82
- Archives of endocrinology and metabolism 70(4)
- Natália Nachbar Hupalowski
- Claudia Pinheiro Sanches Rocha
- Vicente F C Andrade
- Cesar Luiz Boguszewski
- Victoria Zeghbi Cochenski Borba
- PubMed: 42155079
- DOI: 10.20945/2359-4292-2026-0048
5 Insights on- Moderate evidence
The effect of vitamin C supplementation on blood pressure in adults: an umbrella review of meta-analyses of randomized clinical trials.
- 2026
- Meta-Analysis · n = 17
- Food & function 17(6)
- Ali Kosari
- Hossein Shahinfar
- Kimia Rostampour
- Seyedeh Ghazal Mirhosseini
- Sepideh Soltani
- PubMed: 41784995
- DOI: 10.1039/d5fo03679h
- High evidence
- Rigorous Journal
The influence of pepper-derived compounds on blood pressure and heart rate: a systematic review and meta-analysis of randomized controlled trials.
- 2026
- Review
- Food & function 17(11)
- Peng Cheng
- Tianyu Liang
- Kousalya Prabahar
- Jiechao Hu
- Weiling Ye
- PubMed: 42148967
- DOI: 10.1039/d6fo00419a
- Moderate evidence
- Rigorous Journal
Blueberry anthocyanin supplementation shows favorable trends in glycemic control and alters the gut microbiota in type 2 diabetes patients: a pilot study.
- 2026
- Clinical Trial
- Food & function 17(8)
- Xindi Hu
- Lujing Xu
- Ying Li
- Xingyu Zhao
- Yakun Xing
- Jin Feng
- Jiawei Zheng
- Cheng Xue
- Wuyang Huang
- Wuyang Huang
- Shan Lu
- PubMed: 41915410
- DOI: 10.1039/d5fo05613f
- High evidence
- Rigorous Journal
Impact of Subgingival Lactobacillus reuteri Probiotic Therapy on Clinical Outcomes and Porphyromonas gingivalis Quantification in Peri-Implant Disease: A Prospective RT-PCR-Based Clinical Study.
- 2026
- RCT · n = 26
- Journal of long-term effects of medical implants 36(1)
- Karthick Kamalakannan
- Arvina Rajasekar
- PubMed: 41662654
- DOI: 10.1615/jlongtermeffmedimplants.2025060737
5 Insights on- High evidence
Unravelling the Link between Polyphenol Intake and the Risk of Digestive System Cancer: An Umbrella Review Using Meta-Analyses and Systematic Reviews.
- 2026
- Systematic Review
- Expert reviews in molecular medicine 28
- Arezo Amjadi
- Hamid Abbasi
- Atefeh Tahavorgar
- Mohammadreza Esfahanian
- Mahdie Torkaman
- Adel Shahrokhi Sardoo
- Ali Erfanimanesh
- Ali Shamsi-Goushki
- Mohammad Esmail Akbari
- Barbod Alhouei
- Maryam Gholamalizadeh
- Saeid Doaei
- PubMed: 41502351
- DOI: 10.1017/erm.2025.10027
- High evidence
A meta-analysis of the literature evaluating the impact of vitamin D on female fertility and ovarian reserve function.
- 2026
- Meta-Analysis
- Revista da Escola de Enfermagem da U S P 60
- Shanfei Zhao
- Wenling Zheng
- Guanyun Long
- Guanglin Liang
- PubMed: 41670949
- DOI: 10.1590/1980-220x-reeusp-2025-0382en
- High evidence
The effect of saffron supplementation on indices of oxidative stress, inflammation, mental health, and quality of life in patients with Parkinson's disease: a randomized, triple-blind, placebo-controlled clinical trial.
- 2026
- RCT · n = 92
- Food & function 17(2)
- Zahra Hajhashemy
- Mohammad Bagherniya
- Omid Sadeghi
- Fariborz Khorvash
- Gholamreza Askari
- PubMed: 41439298
- DOI: 10.1039/d5fo01924a
13 Insights on- Reduced Depression Symptoms
- Reduced Anxiety
- Improved Sleep Quality
- Reduced C-Reactive Protein Levels
- Reduced Fatigue
- Reduced Malondialdehyde
- Reduced Cognitive Impairment
- Improved Cognitive Status
- Improved Mobility
- Reduced Distress
- Improved Daily Activity Level
- Reduced Bodily Discomfort
- Improved Parkinson's Disease Summary Index
- High evidence
- Rigorous Journal
Polyphenol consumption and neurodegeneration risk: a systematic meta-analysis of randomized controlled trials bridging nutrition and cognitive health.
- 2026
- Meta-Analysis · n = 849
- Food & function 17(3)
- Xiaomei Wang
- Jiao Yang
- Jiayuan Zhang
- Gaihong Yu
- Jian Zhu
- Yingli Nie
- PubMed: 41524705
- DOI: 10.1039/d5fo05135e
- High evidence
- Rigorous Journal
Effects of olive leaf polyphenols on blood lipid profiles and cardiovascular risk markers in healthy and at-risk populations: a narrative review.
- 2026
- Review
- Food & function 17(8)
- Sanne L M van Stratum
- Yala Stevens
- Jogchum Plat
- PubMed: 41878818
- DOI: 10.1039/d5fo04678e
4 Insights on- Moderate evidence
- Rigorous Journal
Saccharomyces boulardii supplementation does not affect anaerobic power gain induced by short-term sprint interval training in physically active individuals.
- 2025
- RCT · n = 8
- Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 58
- A S R Hudson
- A M T Lisboa
- P V R Andrade
- R S Bruzzi
- Y A T Martins
- D D Soares
- F S Martins
- S P Wanner
- PubMed: 40136227
- DOI: 10.1590/1414-431x2025e14196
- High evidence
Comparative efficacy and tolerability of nutraceuticals for depressive disorder: A systematic review and network meta-analysis.
- 2025
- Systematic Review · n = 437
- Psychological medicine 55
- Ying-Chih Cheng
- Wei-Lieh Huang
- Wen-Yin Chen
- Yu-Chen Huang
- Po-Hsiu Kuo
- Yu-Kang Tu
- PubMed: 40314175
- DOI: 10.1017/s0033291725000996
- High evidence
Synbiotic combination of 2'-fucosyllactose and Bifidobacterium mitigates neurodevelopmental disorders and ASD-like behaviors induced by valproic acid.
- 2025
- Food & function 16(7)
- Ying He
- Bo Zhang
- Yu Xin
- Wenxiu Wang
- Xue Wang
- Zhuo Liu
- Yongbo She
- Rui Guo
- Gengjie Jia
- Shan Wu
- Zhigang Liu
- PubMed: 40165714
- DOI: 10.1039/d4fo06234e
6 Insights on- Low evidence
- Rigorous Journal
- Animal Study
Effects of green tea supplementation on antioxidant status and inflammatory markers in adults: a grade-assessed systematic review and dose-response meta-analysis of randomised controlled trials.
- 2025
- Meta-Analysis
- Journal of nutritional science 14
- Mohammad Jafar Dehzad
- Hamid Ghalandari
- Mehran Nouri
- Maede Makhtoomi
- Moein Askarpour
- PubMed: 40160899
- DOI: 10.1017/jns.2025.13
8 Insights on- High evidence
Substituting animal protein with black soymilk reduces advanced glycation end product level and improves gut microbiota composition in obese prediabetic individuals: a randomized crossover intervention trial.
- 2025
- RCT
- Food & function 16(1)
- Yu-Ho Chang
- Pei-Ni Lee
- Cheng-Hsu Chen
- Hsin-Yi Yang
- Chi-Hao Wu
- Jia-Yau Doong
- Wan-Ju Yeh
- PubMed: 39651546
- DOI: 10.1039/d4fo04717f
5 Insights on- High evidence
- Rigorous Journal