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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Probiotics for the Treatment of Atopic Dermatitis in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
- 2017-09-06
- Meta-Analysis
- Frontiers in cellular and infection microbiology 7
- - Ruixue Huang
  - Huacheng Ning
  - Minxue Shen
  - Jie Li
  - Jianglin Zhang
  - Xiang Chen
- PubMed: 28932705
- DOI: 10.3389/fcimb.2017.00392
1 Insight on
- Reduced SCORAD Index
- High evidence
Lactic acid bacteria isolated from yak milk show probiotic potential
- 2017-09-06
- Applied Microbiology and Biotechnology 101(20)
- - M. Kaur
  - Harjodh Singh
  - Manoj Jangra
  - L. Kaur
  - Pallavi Jaswal
  - Chetna Dureja
  - H. Nandanwar
  - S. R. Chaudhuri
  - M. Raje
  - Sunita Mishra
  - A. K. Pinnaka
- PubMed: 28879447
- DOI: 10.1007/s00253-017-8473-4
4 Insights on
- Low evidence
Oral herbal medicines marketed in Brazil for the treatment of osteoarthritis: A systematic review and meta-analysis.
- 2017-09-05
- Meta-Analysis · n = 741
- Phytotherapy research : PTR 31(11)
- - Mariana Del Grossi Moura
  - Luciane Cruz Lopes
  - Maique Weber Biavatti
  - Sean Alexander Kennedy
  - Maria Carolina de Oliveira E Silva
  - Marcus Tolentino Silva
  - Cristiane de Cássia Bergamaschi
- PubMed: 28872719
- DOI: 10.1002/ptr.5910
2 Insights on
- Reduced Pain
- Improved Physical Function
- High evidence
A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome: results from a randomized double-blind placebo-controlled pilot trial.
- 2017-09-04
- RCT
- BMC complementary and alternative medicine 17(1)
- - Iris Pinheiro
  - Larry Robinson
  - An Verhelst
  - Massimo Marzorati
  - Björn Winkens
  - Pieter Van den Abbeele
  - Sam Possemiers
- PubMed: 28870194
- DOI: 10.1186/s12906-017-1948-0
2 Insights on
- Improved Quality of Life
- Modulated Gut Microbiome Composition
- High evidence
A long and abundant non-coding RNA in Lactobacillus salivarius
- 2017-09-01
- Microbial Genomics 3(9)
- - Fabien J. Cousin
  - Denise B. Lynch
  - Victoria Chuat
  - M. Bourin
  - P. G. Casey
  - M. Dalmasso
  - H. Harris
  - Angela McCann
  - P. O’Toole
- PubMed: 29114404
- DOI: 10.1099/mgen.0.000126
2 Insights on
- Improved Host-Gut Microbiota Related Molecular Adaptation
- Altered Intestinal Transit
- Low evidence
- Rigorous Journal
Effect of Foeniculum vulgare Mill. (fennel) on menopausal symptoms in postmenopausal women: a randomized, triple-blind, placebo-controlled trial.
- 2017-09-01
- RCT · n = 45
- Menopause (New York, N.Y.) 24(9)
- - Fatemeh Rahimikian
  - Roja Rahimi
  - Parvin Golzareh
  - Reza Bekhradi
  - Abbas Mehran
- PubMed: 28509813
- DOI: 10.1097/gme.0000000000000881
1 Insight on
- Reduced Menopausal Symptoms
- High evidence
A combination of coenzyme Q10, feverfew and magnesium for migraine prophylaxis: a prospective observational study.
- 2017-08-30
- Observational · n = 68
- BMC complementary and alternative medicine 17(1)
- - Angèle Guilbot
  - Marie Bangratz
  - Samira Ait Abdellah
  - Christian Lucas
- PubMed: 28854909
- DOI: 10.1186/s12906-017-1933-7
5 Insights on
- Moderate evidence
Differential intestinal anti-inflammatory effects of Lactobacillus fermentum and Lactobacillus salivarius in DSS mouse colitis: impact on microRNAs expression and microbiota composition.
- 2017-08-29
- RCT · n = 10
- Molecular Nutrition & Food Research 61(11)
- - A. Rodríguez‐Nogales
  - F. Algieri
  - J. Garrido-Mesa
  - T. Vezza
  - M. P. Utrilla
  - N. Chueca
  - Federico García
  - M. Olivares
  - M. Rodríguez-Cabezas
  - J. Gálvez
- PubMed: 28752563
- DOI: 10.1002/mnfr.201700144
12 Insights on
- Low evidence
- Highly Cited
- Animal Study
Dual function of Lactobacillus kefiri DH5 in preventing high-fat-diet-induced obesity: direct reduction of cholesterol and upregulation of PPAR-α in adipose tissue.
- 2017-08-29
- Clinical Trial
- Molecular Nutrition & Food Research 61(11)
- - Dong‐Hyeon Kim
  - Dana Jeong
  - Il‐Byeong Kang
  - Hyunsook Kim
  - K. Song
  - K. Seo
- PubMed: 28691342
- DOI: 10.1002/mnfr.201700252
7 Insights on
- Low evidence
- Highly Cited
- Animal Study
Comparison of the effect of lavender and bitter orange on sleep quality in postmenopausal women: A triple-blind, randomized, controlled clinical trial.
- 2017-08-25
- RCT · n = 52
- Women & health 58(8)
- - Mahin Kamalifard
  - Azizeh Farshbaf-Khalili
  - Mahsa Namadian
  - Yunes Ranjbar
  - Sepideh Herizchi
- PubMed: 28749734
- DOI: 10.1080/03630242.2017.1353575
1 Insight on
- Improved Sleep Quality
- High evidence
Probiotic Bifidobacterium bifidum G9‐1 attenuates 5‐fluorouracil‐induced intestinal mucositis in mice via suppression of dysbiosis‐related secondary inflammatory responses
- 2017-08-24
- Clinical Trial
- Clinical and Experimental Pharmacology and Physiology 44(10)
- - S. Kato
  - N. Hamouda
  - Yoshitaro Kano
  - Yousuke Oikawa
  - Yoshiki Tanaka
  - Kenjiro Matsumoto
  - K. Amagase
  - M. Shimakawa
- PubMed: 28590519
- DOI: 10.1111/1440-1681.12792
3 Insights on
- Low evidence
- Animal Study
Streptococcus thermophilus NCIMB 41856 ameliorates signs of colitis in an animal model of inflammatory bowel disease.
- 2017-08-24
- Clinical Trial
- Beneficial Microbes 8(4)
- - J. Bailey
  - Valérie Vince
  - Neil Williams
  - T. Cogan
- PubMed: 28618865
- DOI: 10.3920/BM2016.0110
5 Insights on
- Low evidence
- Animal Study
Safety and tolerance of three probiotic strains in healthy infants: a multi-centre randomized, double-blind, placebo-controlled trial.
- 2017-08-24
- RCT
- Beneficial microbes 8(4)
- - S Manzano
  - J De Andrés
  - I Castro
  - J M Rodríguez
  - E Jiménez
  - I Espinosa-Martos
- PubMed: 28555502
- DOI: 10.3920/bm2017.0009
3 Insights on
- High evidence
- Rigorous Journal
Lipid-lowering activity of artichoke extracts: A systematic review and meta-analysis.
- 2017-08-24
- Meta-Analysis · n = 702
- Critical reviews in food science and nutrition 58(15)
- - Amirhossein Sahebkar
  - Matteo Pirro
  - Maciej Banach
  - Dimitri P Mikhailidis
  - Stephen L Atkin
  - Arrigo F G Cicero
- PubMed: 28609140
- DOI: 10.1080/10408398.2017.1332572
4 Insights on
- High evidence
Lactobacillus plantarum Strains Can Enhance Human Mucosal and Systemic Immunity and Prevent Non-steroidal Anti-inflammatory Drug Induced Reduction in T Regulatory Cells
- 2017-08-23
- RCT
- Frontiers in Immunology 8
- - P. de Vos
  - Z. Mujagic
  - B. de Haan
  - R. Siezen
  - P. Bron
  - M. Meijerink
  - J. Wells
  - A. Masclee
  - M. Boekschoten
  - M. Faas
  - F. Troost
- PubMed: 28878772
- DOI: 10.3389/fimmu.2017.01000
6 Insights on
- High evidence
A randomized controlled trial of probiotics for Clostridium difficile infection in adults (PICO).
- 2017-08-23
- RCT · n = 33
- The Journal of antimicrobial chemotherapy 72(11)
- - Anna K Barker
  - Megan Duster
  - Susan Valentine
  - Timothy Hess
  - Laurie Archbald-Pannone
  - Richard Guerrant
  - Nasia Safdar
- PubMed: 28961980
- DOI: 10.1093/jac/dkx254
4 Insights on
- High evidence
Lactobacillus reuteri DSM 17938 and a placebo both significantly reduced symptoms in children with functional abdominal pain.
- 2017-08-22
- RCT · n = 54
- Acta paediatrica (Oslo, Norway : 1992) 106(11)
- - M Maragkoudaki
  - G Chouliaras
  - R Orel
  - A Horvath
  - H Szajewska
  - A Papadopoulou
- PubMed: 28712129
- DOI: 10.1111/apa.13992
5 Insights on
- High evidence
Lactobacillus helveticus-fermented milk containing lactononadecapeptide (NIPPLTQTPVVVPPFLQPE) improves cognitive function in healthy middle-aged adults: a randomised, double-blind, placebo-controlled trial
- 2017-08-18
- RCT
- International Journal of Food Sciences and Nutrition 69(3)
- - K. Ohsawa
  - F. Nakamura
  - Naoto Uchida
  - S. Mizuno
  - H. Yokogoshi
- PubMed: 28819993
- DOI: 10.1080/09637486.2017.1365824
4 Insights on
- High evidence
Peptidoglycan from Immunobiotic Lactobacillus rhamnosus Improves Resistance of Infant Mice to Respiratory Syncytial Viral Infection and Secondary Pneumococcal Pneumonia
- 2017-08-10
- Clinical Trial
- Frontiers in Immunology 8
- - Patricia Clua
  - P. Kanmani
  - H. Zelaya
  - A. Tada
  - A. Kober
  - S. Salva
  - S. Alvarez
  - S. Alvarez
  - H. Kitazawa
  - J. Villena
  - J. Villena
- PubMed: 28848552
- DOI: 10.3389/fimmu.2017.00948
3 Insights on
- Low evidence
- Animal Study
In Vitro and In Vivo Evaluation of Lactobacillus delbrueckii subsp. bulgaricus KLDS1.0207 for the Alleviative Effect on Lead Toxicity
- 2017-08-08
- Nutrients 9(8)
- - Bailiang Li
  - Da Jin
  - Shang-fu Yu
  - Smith Etareri Evivie
  - Zafarullah Muhammad
  - G. Huo
  - Fei Liu
- PubMed: 28786945
- DOI: 10.3390/nu9080845
4 Insights on
- Moderate evidence
Interplay between Lactobacillus rhamnosus GG and Candida and the involvement of exopolysaccharides
- 2017-08-03
- Microbial Biotechnology 10(6)
- - C. Allonsius
  - M. V. D. van den Broek
  - I. De Boeck
  - Shari Kiekens
  - E. Oerlemans
  - F. Kiekens
  - K. Foubert
  - Dieter Vandenheuvel
  - P. Cos
  - P. Delputte
  - S. Lebeer
- PubMed: 28772020
- DOI: 10.1111/1751-7915.12799
3 Insights on
- Low evidence
- Highly Cited
Administration of Lactobacillus salivarius LI01 or Pediococcus pentosaceus LI05 prevents CCl4-induced liver cirrhosis by protecting the intestinal barrier in rats
- 2017-07-31
- Clinical Trial
- Scientific Reports 7(1)
- - D. Shi
  - L. Lv
  - D. Fang
  - Wen-rui Wu
  - Chenxia Hu
  - Lichen Xu
  - Yanfei Chen
  - Jing Guo
  - Xinjun Hu
  - Ang Li
  - F. Guo
  - Jianzhong Ye
  - Yating Li
  - D. Andayani
  - Lanjuan Li
- PubMed: 28761060
- DOI: 10.1038/s41598-017-07091-1
3 Insights on
- Low evidence
- Animal Study
Genome Characteristics of Lactobacillus fermentum Strain JDFM216 for Application as Probiotic Bacteria.
- 2017-07-28
- Journal of Microbiology and Biotechnology 27(7)
- - S. Jang
  - J. Heo
  - M. Park
  - Minho Song
  - J. N. Kim
  - S. Jo
  - Do-Youn Jeong
  - H. Lee
  - Younghoon Kim
  - Sangnam Oh
- PubMed: 28438015
- DOI: 10.4014/jmb.1703.03013
2 Insights on
- Improved Immune Response
- Extended Lifespan
- Low evidence
Safety, Efficacy, and Mechanistic Studies Regarding Citrus aurantium (Bitter Orange) Extract and p-Synephrine.
- 2017-07-28
- Review
- Phytotherapy research : PTR 31(10)
- - Sidney J Stohs
- PubMed: 28752649
- DOI: 10.1002/ptr.5879
2 Insights on
- Increased Blood Pressure
- Increased Heart Rate
- Low evidence
The effects of vitamin D and evening primrose oil co-supplementation on lipid profiles and biomarkers of oxidative stress in vitamin D-deficient women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial.
- 2017-07-25
- RCT · n = 30
- Endocrine research 43(1)
- - Khadijeh Nasri
  - Sedighe Akrami
  - Maryam Rahimi
  - Mohsen Taghizadeh
  - Masoud Behfar
  - Mohammad Reza Mazandaranian
  - Abbas Kheiry
  - Mohammad Reza Memarzadeh
  - Zatollah Asemi
- PubMed: 28742409
- DOI: 10.1080/07435800.2017.1346661
6 Insights on
- High evidence
Evaluation of In Vivo Probiotic Efficiency of Bacillus amyloliquefaciens in Labeo rohita Challenged by Pathogenic Strain of Aeromonas hydrophila MTCC 1739
- 2017-07-25
- RCT
- Probiotics and Antimicrobial Proteins 10(2)
- - Ankita Nandi
  - G. Banerjee
  - Su Dan
  - K. Ghosh
  - A. Ray
- PubMed: 28744833
- DOI: 10.1007/s12602-017-9310-x
2 Insights on
- Improved Immune Function
- Reduced Hepatic Oxidative Stress
- High evidence
Influence of commercial inactivated yeast derivatives on the survival of probiotic bacterium Lactobacillus rhamnosus HN001 in an acidic environment.
- 2017-07-24
- AMB Express 7(1)
- - Mingzhan Toh
  - Shao Quan Liu
- PubMed: 28747041
- DOI: 10.1186/s13568-017-0456-4
1 Insight on
- Improved Survival of Probiotic Bacteria
- Low evidence
Probiotic Characteristics of Lactobacillus curvatus DN317, a Strain Isolated from Chicken Ceca
- 2017-07-24
- Probiotics and Antimicrobial Proteins 9(4)
- - M. Zommiti
  - N. Connil
  - J. B. Hamida
  - M. Ferchichi
- PubMed: 28741151
- DOI: 10.1007/s12602-017-9301-y
2 Insights on
- Reduced Serum Cholesterol Levels
- Improved Anti-Microbial Activity Against Campylobacter Jejuni
- Low evidence
Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis
- 2017-07-17
- Meta-Analysis
- World Journal of Gastroenterology 23(2)
- - Amélie Cayzeele-Decherf
  - Fanny Pélerin
  - S. Leuillet
  - Benoit Douillard
  - B. Housez
  - M. Cazaubiel
  - G. K. Jacobson
  - Peter Jüsten
  - P. Desreumaux
- PubMed: 28127207
- DOI: 10.3748/wjg.v23.i2.336
3 Insights on
- High evidence
- Rigorous Journal
Effect of Lactobacillus on body weight and body fat in overweight subjects: a systematic review of randomized controlled clinical trials
- 2017-07-10
- Systematic Review
- International Journal of Obesity 41(11)
- - Louise Crovesy
  - M. Ostrowski
  - D. M. Ferreira
  - E. L. Rosado
  - Marcia Soares-Mota
- PubMed: 28792488
- DOI: 10.1038/ijo.2017.161
2 Insights on
- Reduced Body Weight
- Reduced Body Fat
- High evidence
- Highly Cited