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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Acetyl-L-carnitine for the prevention of taxane-induced neuropathy in patients with breast cancer: a systematic review and meta-analysis.
- 2023-03
- Review
- Research in pharmaceutical sciences 18(2)
- - Mahnaz Momenzadeh
  - Amir Aria
  - Keyvan Ghadimi
  - Azadeh Moghaddas
- PubMed: 36873277
- DOI: 10.4103/1735-5362.367791
1 Insight on
- Reduced Taxane-Induced Neuropathy
- Low evidence
Infant blood concentrations of folate markers and catabolites are modified by 5,10-methylenetetrahydrofolate reductase C677T genotype and dietary folate source.
- 2023-03
- RCT · n = 182
- The American journal of clinical nutrition 117(3)
- - Rima Obeid
  - Ines Warnke
  - Anja Wittke
  - Igor Bendik
  - Barbara Troesch
  - Rotraut Schoop
  - Christina Hecht
  - Johann Demmelmair
  - Berthold Koletzko
- PubMed: 36872017
- DOI: 10.1016/j.ajcnut.2022.09.002
2 Insights on
- Increased Red Blood Cell Count
- Increased Parabenzoylaminobenzoic Acid Concentration
- High evidence
- Large Human Trial
Antidiabetic properties of mango in animal models and humans: A systematic review.
- 2023-03
- Systematic Review
- Nutrition research (New York, N.Y.) 111
- - Sepideh Alasvand Zarasvand
  - Amy P Mullins
  - Bahram Arjmandi
  - Vivian Haley-Zitlin
- PubMed: 36841190
- DOI: 10.1016/j.nutres.2023.01.003
1 Insight on
- Reduced Blood Glucose Levels
- High evidence
Long-Term Consumption of Nuts (Including Peanuts, Peanut Butter, Walnuts, and Other Nuts) in Relation to Risk of Frailty in Older Women: Evidence from a Cohort Study.
- 2023-03
- Observational · n = 704
- The Journal of nutrition 153(3)
- - Ruibin Wang
  - Marian T Hannan
  - Molin Wang
  - Andrea W Schwartz
  - Esther Lopez-Garcia
  - Francine Grodstein
- PubMed: 36931754
- DOI: 10.1016/j.tjnut.2023.01.003
1 Insight on
- Reduced Frailty Incidence
- High evidence
Evidence for effect of l-serine, a novel therapy for GRIN2B-related neurodevelopmental disorder.
- 2023-03
- Observational
- Molecular genetics and metabolism 138(3)
- - B den Hollander
  - A R J Veenvliet
  - M Rothuizen-Lindenschot
  - P van Essen
  - G Peters
  - A Santos-Gómez
  - M Olivella
  - X Altafaj
  - M M Brands
  - B A W Jacobs
  - C D van Karnebeek
- PubMed: 36758276
- DOI: 10.1016/j.ymgme.2023.107523
4 Insights on
- Low evidence
Therapeutic Effectiveness of Sesame Preparations and its Bioactive Ingredients in Management of Cardiometabolic Syndrome in Diabetes Mellitus: A Systematic Review.
- 2023-03
- Systematic Review
- Current diabetes reviews 19(3)
- - Mohammad Reza Mahmoodi
  - Mohammad Mehdi Abbasi
- PubMed: 35619269
- DOI: 10.2174/1573399818666220525110925
10 Insights on
- High evidence
A systematic review and meta-analysis of almond effect on C-reactive protein and interleukin-6 in adults.
- 2023-03
- Meta-Analysis
- Complementary therapies in medicine 72
- - Mitra Hariri
  - Bahareh Amirkalali
  - Hamid Reza Baradaran
  - Ali Gholami
- PubMed: 36535459
- DOI: 10.1016/j.ctim.2022.102911
2 Insights on
- Reduced Interleukin-6 Levels
- Reduced C-Reactive Protein Levels
- High evidence
Probiotic for pathogen-specific Staphylococcus aureus decolonisation in Thailand: a phase 2, double-blind, randomised, placebo-controlled trial.
- 2023-02
- RCT · n = 115
- The Lancet. Microbe 4(2)
- - Pipat Piewngam
  - Sunisa Khongthong
  - Natthrit Roekngam
  - Yongyuth Theapparat
  - Somkiat Sunpaweravong
  - Damrongsak Faroongsarng
  - Michael Otto
- PubMed: 36646104
- DOI: 10.1016/s2666-5247(22)00322-6
2 Insights on
- Reduced Staphylococcus aureus Colonization
- No Significant Adverse Effects or Microbiome Disruption
- High evidence
- Large Human Trial
The effect of glutathione biosynthesis of Streptococcus thermophilus ST-1 on cocultured Lactobacillus delbrueckii ssp. bulgaricus ATCC11842.
- 2023-02
- Journal of Dairy Science 106(2)
- - Z. Xue
  - X. Cu
  - K. Xu
  - J. Peng
  - H. R. Liu
  - R. Zhao
  - Z. Wang
  - T. Wang
  - Zhen Xu
- PubMed: 36460506
- DOI: 10.3168/jds.2022-22123
3 Insights on
- Low evidence
- Rigorous Journal
Impacts of feeding a Saccharomyces cerevisiae fermentation product on productive performance, and metabolic and immunological responses during a feed-restriction challenge of mid-lactation dairy cows.
- 2023-01
- RCT
- Journal of Dairy Science 106(1)
- - T. Marins
  - F.A. Gutierrez Oviedo
  - M. Costa
  - Y.-C. Chen
  - H. Goodnight
  - M. Garrick
  - D. Hurley
  - J. Bernard
  - I. Yoon
  - S. Tao
- PubMed: 36460513
- DOI: 10.3168/jds.2022-22522
3 Insights on
- High evidence
- Rigorous Journal
Comparing Vitamin D Level Between Patients with Psoriasis and Healthy Individuals: A Systematic Review and Meta-Analysis.
- 2023-01
- Meta-Analysis · n = 1,387
- Journal of evidence-based integrative medicine 28
- - Mahmood Moosazadeh
  - Giovanni Damiani
  - Mohammad Khademloo
  - Motahareh Kheradmand
  - Fatemeh Nabinezhad-Male
  - Amirhossein Hessami
- PubMed: 37936396
- DOI: 10.1177/2515690x231211663
1 Insight on
- Reduced Vitamin D Level
- High evidence
Decreasing the Adverse Effects in Pelvic Radiation Therapy: A Randomized Controlled Trial Evaluating the Use of Probiotics.
- 2023-01
- RCT
- Advances in radiation oncology 8(1)
- - Irini Lazou Ahrén
  - Maria Bjurberg
  - Gunnar Steineck
  - Karin Bergmark
  - Bengt Jeppsson
- PubMed: 36483069
- DOI: 10.1016/j.adro.2022.101089
3 Insights on
- High evidence
Effect of Curcuma longa extract on serum inflammatory markers and MRI-based synovitis in knee osteoarthritis: secondary analyses from the CurKOA randomised trial.
- 2023-01
- RCT · n = 36
- Phytomedicine : international journal of phytotherapy and phytopharmacology 109
- - Zhiqiang Wang
  - Tania Winzenberg
  - Ambrish Singh
  - Dawn Aitken
  - Leigh Blizzard
  - Mikael Boesen
  - Edwin H G Oei
  - Tijmen A van Zadelhoff
  - Venkat Parameswaran
  - Changhai Ding
  - Robert Jones
  - Benny Antony
- PubMed: 36610110
- DOI: 10.1016/j.phymed.2022.154616
5 Insights on
- High evidence
Biological tuners to reshape the bile acid pool for therapeutic purposes in non-alcoholic fatty liver disease.
- 2023-01
- Review
- Clinical science (London, England : 1979) 137(1)
- - Justine Gillard
  - Isabelle A Leclercq
- PubMed: 36601783
- DOI: 10.1042/cs20220697
1 Insight on
- Improved Gut Health
- Low evidence
Gummies candy enriched with Konjac glucomannan reduces hunger intensity and waist circumference of overweight individuals.
- 2023-01
- RCT
- International journal of biological macromolecules 226
- - Ana Carolina Santos Fernandes
  - Luana Muxfeldt
  - Neli Gehlen Motta
  - Calinca Skonieski
  - Karina Raquel Fagundes
  - Gabriela Sandri
  - Daniel Barbosa de Chaves
  - Gabriela Suthovski
  - André Lazarin Gallina
  - Stífani Machado Araujo
  - Dalila Moter Benvegnú
- PubMed: 36435474
- DOI: 10.1016/j.ijbiomac.2022.11.232
2 Insights on
- Reduced Waist Circumference
- Reduced Hunger Intensity
- High evidence
Dietary Saccharomyces cerevisiae improves intestinal flora structure and barrier function of Pekin ducks.
- 2023-01
- RCT · n = 180
- Poultry science 102(1)
- - Wenwen Gao
  - Keying An
  - Peng Li
  - Lei Li
  - Zhaofei Xia
- PubMed: 36436368
- DOI: 10.1016/j.psj.2022.101940
3 Insights on
- Low evidence
- Animal Study
Saffron and Sleep Quality: A Systematic Review of Randomized Controlled Trials.
- 2023-01
- Review · n = 379
- Nutrition and metabolic insights 16
- - Seyyed Kiarash Sadat Rafiei
  - Setare Abolghasemi
  - Mahsa Frashidi
  - Shiva Ebrahimi
  - Fatemeh Gharei
  - Zahra Razmkhah
  - Najmeh Tavousi
  - Behnaz Mahmoudvand
  - Melika Faani
  - Narges Karimi
  - Amir Abdi
  - Mahsa Soleimanzadeh
  - Mahya Ahmadpour Youshanlui
  - Sayedeh-Fatemeh Sadatmadani
  - Reyhaneh Alikhani
  - Yasamin Pishkari
  - Niloofar Deravi
- PubMed: 37484523
- DOI: 10.1177/11786388231160317
2 Insights on
- Improved Sleep Quality
- Increased Daily Sleep Duration
- High evidence
Combination of Astragalus membranaceus and Panax notoginseng as Main Components in the Treatment of Diabetic Nephropathy: A Systematic Review and Meta-Analysis.
- 2023-01
- Review · n = 1,342
- Evidence-based complementary and alternative medicine : eCAM 2023(1)
- - Xiaoning An
  - Youhua Xu
  - Dingkun Gui
- PubMed: 37101717
- DOI: 10.1155/2023/2945234
10 Insights on
- High evidence
Dietary Consumption on Glycemic Control Among Prediabetes: A Review of the Literature.
- 2023-01
- Review
- SAGE open nursing 9
- - Sopida Thipsawat
- PubMed: 38130469
- DOI: 10.1177/23779608231218189
2 Insights on
- Reduced Blood Glucose Levels
- Reduced Hemoglobin A1c
- Low evidence
The use of probiotics and prebiotics can enable the ingestion of dairy products by lactose intolerant individuals.
- 2022-12
- Systematic Review · n = 830
- Clinical nutrition (Edinburgh, Scotland) 41(12)
- - Luiza Scalcon de Oliveira
  - Guilherme Welter Wendt
  - Ana Paula Jaqueline Crestani
  - Kérley Braga Pereira Bento Casaril
- PubMed: 36308983
- DOI: 10.1016/j.clnu.2022.10.003
1 Insight on
- Improved Symptom Relief for Lactose Intolerance
- High evidence
Effectiveness of herbal medicines to prevent and control symptoms of urinary tract infections and to reduce antibiotic use: A literature review.
- 2022-12
- Review
- Integrative medicine research 11(4)
- - Herman van Wietmarschen
  - Noortje van Steenbergen
  - Esther van der Werf
  - Erik Baars
- PubMed: 36345487
- DOI: 10.1016/j.imr.2022.100892
1 Insight on
- Reduced Risk of Urinary Tract Infection
- Low evidence
What is the efficacy of dietary, nutraceutical, and probiotic interventions for the management of gastroesophageal reflux disease symptoms? A systematic literature review and meta-analysis.
- 2022-12
- Meta-Analysis · n = 24
- Clinical nutrition ESPEN 52
- - Zoe Martin
  - Georgia Spry
  - Jen Hoult
  - Isabella R Maimone
  - Xueying Tang
  - Megan Crichton
  - Skye Marshall
- PubMed: 36513474
- DOI: 10.1016/j.clnesp.2022.09.015
1 Insight on
- Improved Gastroesophageal Reflux Disease Symptoms
- High evidence
Chronic Treatment with the Probiotics Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis BB12 Attenuates Motor Impairment, Striatal Microglial Activation, and Dopaminergic Loss in Rats with 6-Hydroxydopamine-induced Hemiparkinsonism.
- 2022-12
- Neuroscience 507
- - Sergio G Cuevas-Carbonell
  - Lizbeth Vásquez-Celaya
  - Daniel García-López
  - Diego Granados-Patrón
  - María Del R García-Miss
  - Fernando J Álvarez-Cervera
  - Mirza Mut-Martín
  - Irving Parra
  - Liliana Mendieta
  - Humberto Salgado
  - Javier Alamilla
  - Reyna Cruz-Bojórquez
  - María Luisa Ávila-Escalante
  - Irma I Aranda-González
  - José L Góngora-Alfaro
- PubMed: 36370934
- DOI: 10.1016/j.neuroscience.2022.11.004
3 Insights on
- Low evidence
- Animal Study
Effects of tart cherry juice consumption on cardio-metabolic risk factors: A systematic review and meta-analysis of randomized-controlled trials.
- 2022-12
- Meta-Analysis
- Complementary therapies in medicine 71
- - Seyedeh Parisa Moosavian
  - Maryam Maharat
  - Mahla Chambari
  - Fateme Moradi
  - Mehran Rahimlou
- PubMed: 36038032
- DOI: 10.1016/j.ctim.2022.102883
10 Insights on
- High evidence
Probiotics and synbiotics in chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
- 2022-12
- Meta-Analysis
- Clinical nutrition (Edinburgh, Scotland) 41(12)
- - Alice van der Schoot
  - Carina Helander
  - Kevin Whelan
  - Eirini Dimidi
- PubMed: 36372047
- DOI: 10.1016/j.clnu.2022.10.015
1 Insight on
- Improved Bowel Movement Frequency
- High evidence
Effects of galactosyltransferase on EPS biosynthesis and freeze-drying resistance of Lactobacillus acidophilus NCFM.
- 2022-12
- Food chemistry. Molecular sciences 5
- - Lingyu Kong
  - Yuze Huang
  - Xiaoqun Zeng
  - Congyan Ye
  - Zhen Wu
  - Yuxing Guo
  - Daodong Pan
- PubMed: 36573108
- DOI: 10.1016/j.fochms.2022.100145
3 Insights on
- Low evidence
The effect of l-arginine supplementation on amelioration of oxygen support in severe COVID-19 pneumonia.
- 2022-12
- RCT · n = 74
- Clinical nutrition ESPEN 52
- - Jananee Muralidharan
  - Sindhu Kashyap
  - Poorvikha S
  - Mathew Jacob
  - Anjali Ollapally
  - Jyothi Idiculla
  - John Michael Raj
  - Tinku Thomas
  - Anura V Kurpad
- PubMed: 36513483
- DOI: 10.1016/j.clnesp.2022.09.024
3 Insights on
- High evidence
Bifidobacterium animalis subsp. lactis Bi-07 supports lactose digestion in vitro and in randomized, placebo- and lactase-controlled clinical trials
- 2022-12
- RCT
- The American Journal of Clinical Nutrition 116(6)
- - Pia Rasinkangas
  - S. Forssten
  - M. Marttinen
  - A. Ibarra
  - G. Bothe
  - J. Junnila
  - R. Uebelhack
  - Y. Donazzolo
  - A. Ouwehand
- PubMed: 36149331
- DOI: 10.1093/ajcn/nqac264
5 Insights on
- High evidence
Lactobacillus paracasei IMC 502 ameliorate type 2 diabetes by mediating gut microbiota-SCFAs-hormone/inflammation pathway in mice.
- 2022-11
- Clinical Trial
- Journal of the Science of Food and Agriculture 103(6)
- - Yuxiang Gu
  - Haoran Chen
  - Xing Li
  - Dan Li
  - Yue Sun
  - Lin Yang
  - Ying Ma
  - E. Chan
- PubMed: 36221226
- DOI: 10.1002/jsfa.12267
11 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Bach Flower Remedies as Complementary Therapies in Health Care: A Scope Review.
- 2022-11
- Review
- Holistic nursing practice 36(6)
- - Mayara Araújo Rocha
  - Cintia Galvão Queiroz
  - Kauanny Vitoria Gurgel Dos Santos
  - Joyce Karolayne Dos Santos Dantas
  - Sara Cristina Matias de Araujo
  - Samia Valeria Ozorio Dutra
  - Daniele Vieira Dantas
  - Rodrigo Assis Neves Dantas
- PubMed: 36255345
- DOI: 10.1097/hnp.0000000000000552
4 Insights on
- Low evidence