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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Cupuassu juice fermentation by lactiplantibacillus plantarum Lp62 produces an antioxidant enriched probiotic beverage.
- 2023-03-01
- Letters in Applied Microbiology 76(3)
- - Lucas Alvarenga da Silva
  - Bianca Silva de Vasconcelos
  - D. K. T. Moreira
  - R. Rezende
  - C. C. Romano
  - Thalis Ferreira Dos Santos
- PubMed: 36881723
- DOI: 10.1093/lambio/ovad032
2 Insights on
- Reduced Pathogen Activity
- Increased Antioxidant Capacity
- Low evidence
Role of Phytotherapy in the Management of BPH: A Summary of the Literature.
- 2023-02-28
- Review
- Journal of clinical medicine 12(5)
- - Vaki Antoniou
  - Vineet Gauhar
  - Sachin Modi
  - Bhaskar Kumar Somani
- PubMed: 36902686
- DOI: 10.3390/jcm12051899
1 Insight on
- Improved Lower Urinary Tract Symptoms
- Low evidence
Lacticaseibacillus paracasei GM-080 Ameliorates Allergic Airway Inflammation in Children with Allergic Rhinitis: From an Animal Model to a Double-Blind, Randomized, Placebo-Controlled Trial
- 2023-02-28
- RCT · n = 122
- Cells 12(5)
- - E. Lin
  - Wen-Wei Chang
  - Jhih-Hua Jhong
  - W. Tsai
  - Chia-Hsuan Chou
  - I-Jen Wang
- PubMed: 36899903
- DOI: 10.3390/cells12050768
5 Insights on
- Low evidence
- Animal Study
Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on feasibility and tolerability.
- 2023-02-28
- RCT
- EBioMedicine 90
- - Anoop Nambiar
  - Dean Kellogg
  - Jaime Justice
  - Martin Goros
  - Jonathan Gelfond
  - Rodolfo Pascual
  - Shahrukh Hashmi
  - Michal Masternak
  - Larissa Prata
  - Nathan LeBrasseur
  - Andrew Limper
  - Stephen Kritchevsky
  - Nicolas Musi
  - Tamara Tchkonia
  - James Kirkland
- PubMed: 36857968
- DOI: 10.1016/j.ebiom.2023.104481
3 Insights on
- High evidence
- Highly Cited
Exopolysaccharide-producing Lacticaseibacillus paracasei strains isolated from kefir as starter for functional dairy products
- 2023-02-24
- Frontiers in Microbiology 14
- - A. Bengoa
  - M. Dueñas
  - A. Prieto
  - G. L. Garrote
  - A. Abraham
- PubMed: 36910219
- DOI: 10.3389/fmicb.2023.1110177
1 Insight on
- Reduced Salmonella Infection
- Low evidence
Orally administered Lactiplantibacillus plantarum OLL2712 decreased intestinal permeability, especially in the ileum: Ingested lactic acid bacteria alleviated obesity-induced inflammation by collaborating with gut microbiota
- 2023-02-23
- Frontiers in Immunology 14
- - Yimei Wang
  - Tomohiro Takano
  - Yingyu Zhou
  - Rong Wang
  - T. Toshimitsu
  - T. Sashihara
  - M. Tanokura
  - T. Miyakawa
  - H. Nakajima-Adachi
  - S. Hachimura
- PubMed: 36911680
- DOI: 10.3389/fimmu.2023.1123052
3 Insights on
- Low evidence
Safety, tolerability, and acceptability of Lactobacillus crispatus CTV-05 (LACTIN-V) in pregnant women at high-risk of preterm birth.
- 2023-02-23
- Clinical Trial · n = 73
- Beneficial Microbes 14(1)
- - E. Bayar
  - D. MacIntyre
  - L. Sykes
  - K. Mountain
  - T. Parks
  - P. Lee
  - P. Bennett
- PubMed: 36815494
- DOI: 10.3920/BM2022.0084
13 Insights on
- High evidence
Combination of heat-killed Lactiplantibacillus plantarum YIT 0132 (LP0132) and oral immunotherapy in cow's milk allergy: a randomised controlled trial.
- 2023-02-23
- RCT · n = 61
- Beneficial Microbes 14(1)
- - K. Yamamoto-Hanada
  - M. Sato
  - K. Toyokuni
  - M. Irahara
  - E. Hiraide-Kotaki
  - N. Harima-Mizusawa
  - H. Morita
  - K. Matsumoto
  - Y. Ohya
- PubMed: 36815492
- DOI: 10.3920/BM2022.0064
9 Insights on
- High evidence
Negligible Effects of Nutraceuticals from Beetroot Extract on Cardiovascular and Autonomic Recovery Response following Submaximal Aerobic Exercise in Physically Active Healthy Males: A Randomized Trial.
- 2023-02-23
- RCT
- International journal of environmental research and public health 20(5)
- - Cicero Jonas R Benjamim
  - Francisco Welington de Sousa Júnior
  - Andrey Alves Porto
  - Camila Venancia Guerra Andrade
  - Maria Íris L Saraiva de Figueiredo
  - Cicera Josilânia R Benjamim
  - Guilherme da Silva Rodrigues
  - Elida M Braga Rocha
  - Taisy Ferro Cavalcante
  - David M Garner
  - Vitor Engracia Valenti
  - Carlos R Bueno Júnior
- PubMed: 36901028
- DOI: 10.3390/ijerph20054019
6 Insights on
- High evidence
Ingestion of Lacticaseibacillus rhamnosus Fmb14 prevents depression-like behavior and brain neural activity via the microbiota-gut-brain axis in colitis mice.
- 2023-02-23
- Clinical Trial
- Food & Function 14(4)
- - Hongyuan Zhao
  - Xiaoyu Chen
  - Li Zhang
  - Chao Tang
  - Fanqiang Meng
  - Libang Zhou
  - Ping Zhu
  - Zhaoxin Lu
  - Yingjian Lu
- PubMed: 36748225
- DOI: 10.1039/d2fo04014j
6 Insights on
- Low evidence
- Animal Study
Effects of Clostridium butyricum as an Antibiotic Alternative on Growth Performance, Intestinal Morphology, Serum Biochemical Response, and Immunity of Broilers
- 2023-02-22
- RCT
- Antibiotics 12(3)
- - Tiantian Yang
  - Mengsi Du
  - Jing Zhang
  - Baseer Ahmad
  - Qiang Cheng
  - Xiaobing Wang
  - Zaheer Abbas
  - Yucui Tong
  - Jinzhuan Li
  - Yichen Zhou
  - Rijun Zhang
  - Dayong Si
- PubMed: 36978300
- DOI: 10.3390/antibiotics12030433
3 Insights on
- High evidence
Comment on Sung et al. Body Fat Reduction Effect of Bifidobacterium breve B-3: A Randomized, Double-Blind, Placebo Comparative Clinical Trial. Nutrients 2023, 15, 28
- 2023-02-22
- RCT
- Nutrients 15(5)
- - S. Y. Lee
- PubMed: 36904094
- DOI: 10.3390/nu15051093
2 Insights on
- Reduced Body Fat
- Reduced Body Fat Mass
- High evidence
Eight-week supplementation of Aronia berry extract promoted the glutathione defence system against acute aerobic exercise-induced oxidative load immediately and 30 min post-exercise in healthy adults: a double-blind, randomised controlled trial.
- 2023-02-20
- RCT · n = 70
- Journal of human nutrition and dietetics : the official journal of the British Dietetic Association 36(4)
- - Jae-Won Chung
  - Ji-Eon Kim
  - Yea-Eun Nam
  - Woo-Shik Kim
  - Insoo Lee
  - Sung-Vin Yim
  - Oran Kwon
- PubMed: 36727618
- DOI: 10.1111/jhn.13150
6 Insights on
- High evidence
Short-Term Intake of Theobroma grandiflorum Juice Fermented with Lacticaseibacillus rhamnosus ATCC 9595 Amended the Outcome of Endotoxemia Induced by Lipopolysaccharide
- 2023-02-20
- Clinical Trial · n = 12
- Nutrients 15(4)
- - Adrielle Zagmignan
  - Yasmim Costa Mendes
  - G. P. Mesquita
  - Gabrielle Damasceno Costa Dos Santos
  - L. S. Silva
  - Amanda Caroline de Souza Sales
  - Simeone Júlio dos Santos Castelo Branco
  - A. R. G. Junior
  - José Manuel Noguera Bazán
  - Edinalva Rodrigues Alves
  - Bárbara Lima de Almeida
  - Anne Karoline Maiorana Santos
  - Wellyson da Cunha Araújo Firmo
  - M. Silva
  - A. J. Cantanhede Filho
  - Rita Miranda
  - Luís Cláudio Nascimento da Silva
- PubMed: 36839417
- DOI: 10.3390/nu15041059
2 Insights on
- Reduced Inflammation Levels
- Reduced Organ Weight
- Low evidence
- Animal Study
Randomized controlled trial demonstrates response to a probiotic intervention for metabolic syndrome that may correspond to diet.
- 2023-02-19
- RCT · n = 39
- Gut microbes 15(1)
- - Hannah C Wastyk
  - Dalia Perelman
  - Madeline Topf
  - Gabriela K Fragiadakis
  - Jennifer L Robinson
  - Justin L Sonnenburg
  - Christopher D Gardner
  - Erica D Sonnenburg
- PubMed: 36803658
- DOI: 10.1080/19490976.2023.2178794
2 Insights on
- Reduced Diastolic Blood Pressure
- Improved Triglyceride Levels
- High evidence
Limosilactobacillus reuteri normalizes blood–brain barrier dysfunction and neurodevelopment deficits associated with prenatal exposure to lipopolysaccharide
- 2023-02-17
- Clinical Trial
- Gut Microbes 15(1)
- - Jing Lu
  - Xiaobing Fan
  - Lei Lu
  - Yueyue Yu
  - E. Markiewicz
  - Jessica C. Little
  - A. Sidebottom
  - E. Claud
- PubMed: 36799469
- DOI: 10.1080/19490976.2023.2178800
1 Insight on
- Improved Cognitive Function
- Low evidence
- Animal Study
Lactobacillus for the treatment and prevention of atopic dermatitis: Clinical and experimental evidence.
- 2023-02-16
- Review
- Frontiers in cellular and infection microbiology 13
- - Anni Xie
  - Ailing Chen
  - Yuqing Chen
  - Zichen Luo
  - Shanyu Jiang
  - Daozhen Chen
  - Renqiang Yu
- PubMed: 36875529
- DOI: 10.3389/fcimb.2023.1137275
1 Insight on
- Improved Atopic Dermatitis Symptoms
- Low evidence
Preliminary data revealing efficacy of Streptococcus salivarius K12 (SSK12) in Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis (PFAPA) syndrome: A multicenter study from the AIDA Network PFAPA syndrome registry
- 2023-02-16
- Observational · n = 85
- Frontiers in Medicine 10
- - F. La Torre
  - J. Sota
  - A. Insalaco
  - G. Conti
  - E. Del Giudice
  - R. Lubrano
  - L. Breda
  - M. Maggio
  - A. Civino
  - Violetta Mastrorilli
  - Robert LoConte
  - Marco Francesco Natale
  - C. Celani
  - Mery Romeo
  - S. Patroniti
  - Cristina Gentile
  - A. Vitale
  - V. Caggiano
  - C. Gaggiano
  - F. Diomeda
  - M. Cattalini
  - G. Lopalco
  - G. Emmi
  - P. Parronchi
  - S. Gentileschi
  - F. Cardinale
  - E. Aragona
  - F. Shahram
  - A. Marino
  - P. Barone
  - C. Moscheo
  - B. Ozkiziltas
  - F. Carubbi
  - Ohoud AlAhmed
  - Ludovica Iezzi
  - B. Ogunjimi
  - A. Mauro
  - M. Tarsia
  - Ayman Magdy Ahmed Mahmoud
  - Henrique Giardini
  - P. Sfikakis
  - K. Laskari
  - E. Więsik-Szewczyk
  - J. Hernández-Rodríguez
  - B. Frediani
  - Verónica Gómez-Caverzaschi
  - A. Tufan
  - I. Almaghlouth
  - A. Balistreri
  - Gaafar Ragab
  - Claudia Fabiani
  - L. Cantarini
  - D. Rigante
- PubMed: 36873863
- DOI: 10.3389/fmed.2023.1105605
15 Insights on
- Moderate evidence
Impact of Oats on Appetite Hormones and Body Weight Management: A Review.
- 2023-02-15
- Review
- Current nutrition reports 12(1)
- - Amna Shehzad
  - Roshina Rabail
  - Seemal Munir
  - Hamza Jan
  - Diego Fernández-Lázaro
  - Rana Muhammad Aadil
- PubMed: 36790719
- DOI: 10.1007/s13668-023-00454-3
8 Insights on
- Low evidence
Identification of a Novel Strain Lactobacillus Reuteri and Anti-Obesity Effect through Metabolite Indole-3-Carboxaldehyde in Diet-Induced Obese Mice.
- 2023-02-14
- Clinical Trial
- Journal of Agricultural and Food Chemistry 71(7)
- - Shuhua Shan
  - Qinqin Qiao
  - Ruopeng Yin
  - Lizhen Zhang
  - Jiangying Shi
  - Wenjing Zhao
  - Jiaqi Zhou
  - Zhuoyu Li
- PubMed: 36786753
- DOI: 10.1021/acs.jafc.2c05764
2 Insights on
- Reduced Obesity
- Reduced Lipid Deposition
- Low evidence
- Animal Study
Effects of Dietary Pediococcus acidilactici and Isomaltooligosaccharide on Growth Performance, Immunity, and Antioxidant Defense in Juvenile Common Carp
- 2023-02-14
- RCT · n = 360
- Aquaculture Nutrition 2023
- - M. Maniat
  - A. Salati
  - N. Zanguee
  - Seyed Mohammad Mousavi
  - S. Hoseinifar
- PubMed: 36860979
- DOI: 10.1155/2023/1808640
3 Insights on
- Low evidence
- Animal Study
The Ability of Streptococcus thermophilus BT01 to Modulate Urease Activity in Healthy Subjects' Fecal Samples Depends on the Biomass Production Process.
- 2023-02-14
- n = 20
- Molecular Nutrition & Food Research 67(6)
- - Martinović Anđela
  - Chittaro Marco
  - Mora Diego
  - Arioli Stefania
- PubMed: 36708131
- DOI: 10.1002/mnfr.202200529
1 Insight on
- Reduced Urease Activity
- Low evidence
Anti-inflammatory and wound healing properties of lactic acid bacteria and its peptides.
- 2023-02-13
- Review
- Folia microbiologica 68(3)
- - Parikhshith Saravanan
  - Pooja R
  - Nanditaa Balachander
  - Kesav Ram Singh K
  - Silpa S
  - Rupachandra S
- PubMed: 36780113
- DOI: 10.1007/s12223-022-01030-y
2 Insights on
- Improved Wound Healing
- Reduced Inflammation
- Low evidence
Effect of Tea Tree Oil and Coconut Oil on Nipple Crack Formation in the Early Postpartum Period.
- 2023-02-10
- RCT · n = 90
- Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine 18(3)
- - Ebru Şahin
  - Fatma Yildirim
  - Nuriye Büyükkayaci Duman
- PubMed: 36763614
- DOI: 10.1089/bfm.2022.0260
2 Insights on
- Reduced Nipple Pain
- Reduced Nipple Crack Formation
- High evidence
The Effects of Fenugreek Seed Consumption on Blood Pressure: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
- 2023-02-10
- Meta-Analysis · n = 373
- High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension 30(2)
- - Mohammad Reza Amini
  - Nastaran Payandeh
  - Fatemeh Sheikhhossein
  - Sanaz Pourreza
  - Hamid Ghalandari
  - Moein Askarpour
  - Azita Hekmatdoost
- PubMed: 36763260
- DOI: 10.1007/s40292-023-00565-6
2 Insights on
- Reduced Diastolic Blood Pressure
- Reduced Systolic Blood Pressure
- High evidence
The Current and Future Perspectives of Postbiotics.
- 2023-02-10
- Review
- Probiotics and antimicrobial proteins 15(6)
- - Bing Liang
  - Dongming Xing
- PubMed: 36763279
- DOI: 10.1007/s12602-023-10045-x
5 Insights on
- Moderate evidence
- Rigorous Journal
Efficacy of Bacillus clausii in Pediatric Functional Constipation: A Pilot of a Randomized, Double-Blind, Placebo-Controlled Trial.
- 2023-02-09
- RCT · n = 38
- Indian pediatrics 60(6)
- - Ponlakit Lojanatorn
  - Jirachart Phrommas
  - Pornthep Tanpowpong
  - Songpon Getsuwan
  - Chatmanee Lertudomphonwanit
  - Suporn Treepongkaruna
- PubMed: 36757002
- DOI: 10.1007/s13312-023-2907-0
5 Insights on
- High evidence
Feasibility Study of Lactobacillus Plantarum 299v Probiotic Supplementation in an Urban Academic Facility among Diverse Pregnant Individuals
- 2023-02-09
- RCT · n = 20
- Nutrients 15(4)
- - Nefertiti OjiNjideka Hemphill
  - Lacey Pezley
  - Alana D. Steffen
  - G. Elam
  - M. Kominiarek
  - A. Odoms-Young
  - Nicollette Kessee
  - Alyshia Hamm
  - L. Tussing-Humphreys
  - M. D. Koenig
- PubMed: 36839232
- DOI: 10.3390/nu15040875
2 Insights on
- Improved Iron Levels
- Improved Tolerability
- High evidence
Potential of Bifidobacterium lactis IDCC 4301 isolated from breast milk‐fed infant feces as a probiotic and functional ingredient
- 2023-02-08
- Food Science & Nutrition 11(4)
- - O-Hyun Ban
  - Won Yeong Bang
  - H. Jeon
  - Y. Jung
  - Jungwoo Yang
  - Dong Hyun Kim
- PubMed: 37051343
- DOI: 10.1002/fsn3.3230
1 Insight on
- Enhanced Antipathogenic Activity
- Low evidence
L-Carnitine and Chronic Kidney Disease: A Comprehensive Review on Nutrition and Health Perspectives.
- 2023-02-08
- Review
- Journal of personalized medicine 13(2)
- - Bharti Sharma
  - Dinesh Kumar Yadav
- PubMed: 36836532
- DOI: 10.3390/jpm13020298
8 Insights on
- Low evidence