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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Lactobacillus reuteri Influences Regrowth of Mutans Streptococci after Full-Mouth Disinfection: A Double-Blind, Randomised Controlled Trial
- 2014-03-10
- RCT · n = 62
- Caries Research 47(4)
- - N. R. Vestman
  - P. Hasslöf
  - M. Keller
  - Elisabeth Granström
  - S. Roos
  - Svante Twetman
  - C. Stecksén-blicks
- PubMed: 23486236
- DOI: 10.1159/000347233
1 Insight on
- Delayed Regrowth of Mutans Streptococci
- High evidence
Lipid-Lowering Effects of Pediococcus acidilactici M76 Isolated from Korean Traditional Makgeolli in High Fat Diet-Induced Obese Mice
- 2014-03-07
- RCT
- Nutrients 6(3)
- - Yeon‐jeong Moon
  - S. Baik
  - Y. Cha
- PubMed: 24609135
- DOI: 10.3390/nu6031016
5 Insights on
- Low evidence
- Animal Study
Lactobacillus brevis Strains from Fermented Aloe vera Survive Gastroduodenal Environment and Suppress Common Food Borne Enteropathogens
- 2014-03-05
- PLoS ONE 9(3)
- - Young‐Wook Kim
  - Young-ju Jeong
  - Ah-Young Kim
  - H. Son
  - Jong-Am Lee
  - Cheong-Hwan Jung
  - Chae-Hyun Kim
  - Jaeman Kim
- PubMed: 24598940
- DOI: 10.1371/journal.pone.0090866
8 Insights on
- Low evidence
- Rigorous Journal
Effect of Bifidobacterium breve M-16V Supplementation on Fecal Bifidobacteria in Preterm Neonates - A Randomised Double Blind Placebo Controlled Trial
- 2014-03-03
- RCT · n = 159
- PLoS ONE 9(3)
- - S. Patole
  - A. Keil
  - An-Yi Chang
  - E. Nathan
  - D. Doherty
  - K. Simmer
  - Meera Esvaran
  - P. Conway
- PubMed: 24594833
- DOI: 10.1371/journal.pone.0089511
10 Insights on
- High evidence
- Highly Cited
- Rigorous Journal
Echinacea for preventing and treating the common cold.
- 2014-02-20
- Meta-Analysis · n = 4,631
- The Cochrane database of systematic reviews 2014(7)
- - Marlies Karsch-Völk
  - Bruce Barrett
  - David Kiefer
  - Rudolf Bauer
  - Karin Ardjomand-Woelkart
  - Klaus Linde
- PubMed: 24554461
- DOI: 10.1002/14651858.cd000530.pub3
2 Insights on
- Reduced Duration of Common Cold
- Reduced Incidence of Common Cold
- High evidence
Lactobacillus paracasei CBA L74 metabolic products and fermented milk for infant formula have anti-inflammatory activity on dendritic cells in vitro and protective effects against colitis and an enteric pathogen in vivo.
- 2014-02-10
- PloS one 9(2)
- - Elena Zagato
  - Erika Mileti
  - Lucia Massimiliano
  - Francesca Fasano
  - Andrea Budelli
  - Giuseppe Penna
  - Maria Rescigno
- PubMed: 24520333
- DOI: 10.1371/journal.pone.0087615
3 Insights on
- Low evidence
Effect of oral administration involving a probiotic strain of Lactobacillus reuteri on pro-inflammatory cytokine response in patients with chronic periodontitis.
- 2014-02-09
- Clinical Trial · n = 24
- Archivum immunologiae et therapiae experimentalis 62(6)
- - Anna K Szkaradkiewicz
  - Janina Stopa
  - Tomasz M Karpiński
- PubMed: 24509697
- DOI: 10.1007/s00005-014-0277-y
6 Insights on
- Moderate evidence
Effect of heat‐killed Lactobacillus brevis SBC8803 on cutaneous arterial sympathetic nerve activity, cutaneous blood flow and transepidermal water loss in rats
- 2014-02-03
- Clinical Trial
- Journal of Applied Microbiology 116(5)
- - Y. Horii
  - H. Kaneda
  - Y. Fujisaki
  - R. Fuyuki
  - Y. Nakakita
  - T. Shigyo
  - K. Nagai
- PubMed: 24410864
- DOI: 10.1111/jam.12435
7 Insights on
- Low evidence
- Animal Study
The effects of active dried and killed dried yeast on subacute ruminal acidosis, ruminal fermentation, and nutrient digestibility in beef heifers.
- 2014-02-01
- RCT · n = 6
- Journal of Animal Science 92(2)
- - D. Vyas
  - Aimable Uwizeye
  - R. Mohammed
  - W. Yang
  - N. Walker
  - K. Beauchemin
- PubMed: 24398831
- DOI: 10.2527/jas.2013-7072
1 Insight on
- Improved Starch Digestibility
- Low evidence
- Highly Cited
- Rigorous Journal
- Animal Study
The effects of live yeast Saccharomyces cerevisiae on postweaning diarrhea, immune response, and growth performance in weaned piglets.
- 2014-02-01
- Journal of Animal Science 92(2)
- - M. Trckova
  - M. Faldyna
  - P. Alexa
  - Z. Sramkova Zajacova
  - E. Gopfert
  - D. Kumprechtová
  - E. Auclair
  - R. D’inca
- PubMed: 24305872
- DOI: 10.2527/jas.2013-6793
2 Insights on
- Improved Growth Performance
- Enhanced Immune Response
- Moderate evidence
- Highly Cited
- Rigorous Journal
Oral administration of Lactobacillus fermentum I5007 favors intestinal development and alters the intestinal microbiota in formula-fed piglets.
- 2014-01-15
- RCT · n = 2
- Journal of Agricultural and Food Chemistry 62(4)
- - Hong Liu
  - Jiang Zhang
  - Shihai Zhang
  - Fengjuan Yang
  - P. Thacker
  - Guolong Zhang
  - S. Qiao
  - Xi Ma
- PubMed: 24404892
- DOI: 10.1021/jf403288r
18 Insights on
- Low evidence
- Highly Cited
- Animal Study
Probiotic gut effect prevents the chronic psychological stress‐induced brain activity abnormality in mice
- 2013-12-30
- Clinical Trial
- Neurogastroenterology & Motility 26(4)
- - A. Ait-Belgnaoui
  - A. Colom
  - V. Braniste
  - L. Ramalho
  - A. Marrot
  - C. Cartier
  - E. Houdeau
  - V. Théodorou
  - T. Tompkins
- PubMed: 24372793
- DOI: 10.1111/nmo.12295
4 Insights on
- Low evidence
- Highly Cited
- Animal Study
Meta‐analysis shows limited evidence for using Lactobacillus acidophilus LB to treat acute gastroenteritis in children
- 2013-12-20
- Meta-Analysis
- Acta Paediatrica 103(3)
- - H. Szajewska
  - M. Ruszczyński
  - S. Kolaček
- PubMed: 24175943
- DOI: 10.1111/apa.12487
3 Insights on
- High evidence
Effect of probiotics on biomarkers of cardiovascular disease: implications for heart-healthy diets.
- 2013-12-13
- Meta-Analysis
- Nutrition Reviews 72(1)
- - D. Dirienzo
- PubMed: 24330093
- DOI: 10.1111/nure.12084
6 Insights on
- High evidence
- Highly Cited
Modulatory effects of Bifidobacterium longum BB536 on defecation in elderly patients receiving enteral feeding.
- 2013-12-10
- RCT · n = 206
- World Journal of Gastroenterology 19(14)
- - Junko Kondo
  - J. Xiao
  - A. Shirahata
  - Mieko Baba
  - Akie Abe
  - Koichi Ogawa
  - T. Shimoda
- PubMed: 23599642
- DOI: 10.3748/wjg.v19.i14.2162
17 Insights on
- High evidence
- Rigorous Journal
Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women
- 2013-12-03
- RCT
- British Journal of Nutrition 111(8)
- - Marina Sánchez
  - C. Darimont
  - V. Drapeau
  - S. Emady-Azar
  - Mélissa Lepage
  - E. Rezzonico
  - C. Ngom-Bru
  - B. Berger
  - Lionel Philippe
  - Corinne Ammon-Zuffrey
  - P. Leone
  - Geneviève Chevrier
  - Emmanuelle St-Amand
  - A. Marette
  - Jean Doré
  - A. Tremblay
- PubMed: 24299712
- DOI: 10.1017/S0007114513003875
7 Insights on
- High evidence
- Highly Cited
Oral Administration of Lactobacillus reuteri during the First Year of Life Reduces Caries Prevalence in the Primary Dentition at 9 Years of Age
- 2013-11-29
- RCT · n = 113
- Caries Research 48(2)
- - Malin Stensson
  - Göran Koch
  - S. Ćorić
  - Thomas R. Abrahamsson
  - M. Jenmalm
  - Dowen Birkhed
  - L. Wendt
- PubMed: 24296746
- DOI: 10.1159/000354412
3 Insights on
- High evidence
- Highly Cited
Soy, red clover, and isoflavones and breast cancer: a systematic review.
- 2013-11-28
- Systematic Review · n = 131
- PloS one 8(11)
- - Heidi Fritz
  - Dugald Seely
  - Gillian Flower
  - Becky Skidmore
  - Rochelle Fernandes
  - Sarah Vadeboncoeur
  - Deborah Kennedy
  - Kieran Cooley
  - Raimond Wong
  - Stephen Sagar
  - Elham Sabri
  - Dean Fergusson
- PubMed: 24312387
- DOI: 10.1371/journal.pone.0081968
5 Insights on
- High evidence
Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study.
- 2013-11-26
- RCT
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 29(7)
- - Rogier Caluwé
  - Stefaan Vandecasteele
  - Bruno Van Vlem
  - Cees Vermeer
  - An S De Vriese
- PubMed: 24285428
- DOI: 10.1093/ndt/gft464
1 Insight on
- Reduced Desphosphorylated-Uncarboxylated Matrix Gla Protein Level
- High evidence
Growth of infants fed formula supplemented with Bifidobacterium lactis Bb12 or Lactobacillus GG: a systematic review of randomized controlled trials
- 2013-11-12
- Systematic Review
- BMC Pediatrics 13(1)
- - H. Szajewska
  - A. Chmielewska
- PubMed: 24215626
- DOI: 10.1186/1471-2431-13-185
1 Insight on
- Increased Head Circumference
- High evidence
- Rigorous Journal
Diet, microbiome, and the intestinal epithelium: an essential triumvirate?
- 2013-11-11
- Review
- BioMed research international 2013
- - Javier Rivera Guzman
  - Victoria Susan Conlin
  - Christian Jobin
- PubMed: 23586037
- DOI: 10.1155/2013/425146
1 Insight on
- Improved Intestinal Barrier Function
- Low evidence
Diet alters probiotic Lactobacillus persistence and function in the intestine.
- 2013-11-11
- Clinical Trial
- Environmental Microbiology 16(9)
- - Sybille Tachon
  - Bokyung Lee
  - M. Marco
- PubMed: 24118739
- DOI: 10.1111/1462-2920.12297
2 Insights on
- Increased Persistence of Probiotics in Fecal Matter
- Reduced Colitis Symptoms
- Low evidence
- Rigorous Journal
- Animal Study
Effect of Yogurt Containing Bifidobacteriumanimalis subsp. lactis DN-173010 Probiotic on Dental Plaque and Saliva in Orthodontic Patients
- 2013-11-06
- RCT · n = 26
- Caries Research 48(1)
- - G. S. Pinto
  - M. Cenci
  - M. Azevedo
  - M. Epifanio
  - M.H. Jones
- PubMed: 24217196
- DOI: 10.1159/000353467
1 Insight on
- Reduced Microbial Counts in Dental Plaque
- High evidence
Injection of Lactobacillus casei strain Shirota affects autonomic nerve activities in a tissue‐specific manner, and regulates glucose and lipid metabolism in rats
- 2013-11-05
- Clinical Trial
- Journal of Diabetes Investigation 5(2)
- - M. Tanida
  - Kazuki Imanishi
  - Haruna Akashi
  - Y. Kurata
  - O. Chonan
  - E. Naito
  - S. Kunihiro
  - M. Kawai
  - Akito Kato-Kataoka
  - T. Shibamoto
- PubMed: 24843755
- DOI: 10.1111/jdi.12141
3 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Exposure of fatty acids after a single oral administration of sacha inchi (Plukenetia volubilis L.) and sunflower oil in human adult subjects.
- 2013-10-29
- RCT
- Toxicology mechanisms and methods 24(1)
- - Gustavo F Gonzales
  - Carla Gonzales
  - Leon Villegas
- PubMed: 24090048
- DOI: 10.3109/15376516.2013.850566
3 Insights on
- High evidence
Vitamin C for asthma and exercise-induced bronchoconstriction.
- 2013-10-23
- Meta-Analysis · n = 419
- The Cochrane database of systematic reviews 2018(6)
- - Stephen J Milan
  - Anna Hart
  - Mark Wilkinson
- PubMed: 24154977
- DOI: 10.1002/14651858.cd010391.pub2
5 Insights on
- High evidence
Pelargonium sidoides extract for treating acute respiratory tract infections.
- 2013-10-22
- Meta-Analysis · n = 819
- The Cochrane database of systematic reviews 2013(10)
- - Antje Timmer
  - Judith Günther
  - Edith Motschall
  - Gerta Rücker
  - Gerd Antes
  - Winfried V Kern
- PubMed: 24146345
- DOI: 10.1002/14651858.cd006323.pub3
2 Insights on
- Complete Resolution of Symptoms
- Reduced Bronchitis Symptoms
- High evidence
Short-term, daily intake of yogurt containing Bifidobacterium animalis ssp. lactis Bf-6 (LMG 24384) does not affect colonic transit time in women
- 2013-10-08
- RCT · n = 68
- British Journal of Nutrition 111(2)
- - D. Merenstein
  - F. D'Amico
  - C. Palese
  - A. Hahn
  - Jessy Sparenborg
  - T. Tan
  - Hillary Scott
  - K. Polzin
  - Lore W Kolberg
  - R. Roberts
- PubMed: 24103188
- DOI: 10.1017/S0007114513002237
4 Insights on
- High evidence
Improvement of gastrointestinal health status in subjects consuming Lactobacillus reuteri NCIMB 30242 capsules: a post-hoc analysis of a randomized controlled trial
- 2013-09-28
- RCT · n = 127
- Expert Opinion on Biological Therapy 13(12)
- - M. Jones
  - C. Martoni
  - J. Ganopolsky
  - I. Sulemankhil
  - P. Ghali
  - S. Prakash
- PubMed: 24074303
- DOI: 10.1517/14712598.2013.833601
4 Insights on
- High evidence
A dried yeast fermentate selectively modulates both the luminal and mucosal gut microbiota and protects against inflammation, as studied in an integrated in vitro approach.
- 2013-09-19
- Journal of agricultural and food chemistry 61(39)
- - Sam Possemiers
  - Iris Pinheiro
  - An Verhelst
  - Pieter Van den Abbeele
  - Lois Maignien
  - Debby Laukens
  - Stuart G Reeves
  - Larry E Robinson
  - Thomas Raas
  - Yves-Jacques Schneider
  - Tom Van de Wiele
  - Massimo Marzorati
- PubMed: 24006902
- DOI: 10.1021/jf402137r
4 Insights on
- Low evidence
- Rigorous Journal