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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Matcha Does Not Affect Electroencephalography during Sleep but May Enhance Mental Well-Being: A Randomized Placebo-Controlled Clinical Trial.
- 2024-08-31
- RCT
- Nutrients 16(17)
- - Yoshitake Baba
  - Takanobu Takihara
  - Noritaka Okamura
- PubMed: 39275223
- DOI: 10.3390/nu16172907
9 Insights on
- High evidence
- Rigorous Journal
Psychobiotic Properties of Lactiplantibacillus plantarum in Neurodegenerative Diseases.
- 2024-08-31
- Review
- International journal of molecular sciences 25(17)
- - Mariagiovanna Di Chiano
  - Fabio Sallustio
  - Daniela Fiocco
  - Maria Teresa Rocchetti
  - Giuseppe Spano
  - Paola Pontrelli
  - Antonio Moschetta
  - Loreto Gesualdo
  - Raffaella Maria Gadaleta
  - Anna Gallone
- PubMed: 39273435
- DOI: 10.3390/ijms25179489
2 Insights on
- Improved Gut-Brain Axis Homeostasis
- Reduced Neurodegenerative Disease-Related Dysfunction
- Moderate evidence
- Rigorous Journal
Evaluation of supplementary carnosine accumulation and distribution: an initial analysis of participants in the Nucleophilic Defense Against PM Toxicity (NEAT) clinical trial.
- 2024-08-31
- RCT
- Amino acids 56(1)
- - Shahid P Baba
  - Alok R Amraotkar
  - David Hoetker
  - Hong Gao
  - Daniel Gomes
  - Jingjing Zhao
  - Michael F Wempe
  - Peter J Rice
  - Andrew P DeFilippis
  - Shesh N Rai
  - C Arden Pope
  - Aruni Bhatnagar
  - Timothy E O'Toole
- PubMed: 39215872
- DOI: 10.1007/s00726-024-03414-5
4 Insights on
- High evidence
Associations of different types of statins with the risk of open-angle glaucoma: a systematic review and network meta-analysis.
- 2024-08-30
- Systematic Review · n = 217
- Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 263(1)
- - Ssu-Yu Pan
  - Yun-Yu Chen
  - Min-Yen Hsu
  - Yi-Jing Sheen
  - Chien-Hsiang Weng
  - Yi-An Lu
  - I-Jong Wang
  - Mei-Hua Wu
  - Chien-Chih Chou
  - Chien-Chih Chou
- PubMed: 39212799
- DOI: 10.1007/s00417-024-06620-9
1 Insight on
- Reduced Glaucoma Onset Risk
- High evidence
The effect of psyllium consumption on blood pressure: Systematic review and dose-response meta-analysis of randomized controlled trials.
- 2024-08-29
- Review · n = 802
- Food science & nutrition 12(10)
- - Zeinab Gholami
  - Zamzam Paknahad
- PubMed: 39479650
- DOI: 10.1002/fsn3.3863
2 Insights on
- Reduced Diastolic Blood Pressure
- Reduced Systolic Blood Pressure
- High evidence
Probiotic bacteria of wild boar origin intended for piglets - An in vitro study.
- 2024-08-29
- Veterinarni medicina 69(8)
- - Iveta Kostovova
  - Katerina Kavanova
  - Monika Moravkova
  - Jan Gebauer
  - Lenka Leva
  - Monika Vicenova
  - Vladimir Babak
  - Martin Faldyna
  - Magdalena Crhanova
- PubMed: 39296628
- DOI: 10.17221/35/2024-vetmed
1 Insight on
- Reduced Pathogen Growth
- Low evidence
Oral supplementation with probiotics, potassium citrate, and magnesium in reducing crystalluria in stone formers: A phase II study.
- 2024-08-29
- Clinical Trial · n = 23
- Urologia 91(4)
- - Matteo Vittori
  - Pierluigi Bove
  - Marta Signoretti
  - Chiara Cipriani
  - Cristiano Gasparoli
  - Michele Antonucci
  - Marco Carilli
  - Francesco Maiorino
  - Valerio Iacovelli
  - Filomena Petta
  - Stefano Travaglia
  - Massimo Panei
  - Pierluigi Russo
  - Riccardo Bertolo
- PubMed: 39206631
- DOI: 10.1177/03915603241272146
1 Insight on
- Reduced Crystalluria
- Moderate evidence
Garlic and Hypertension: Efficacy, Mechanism of Action, and Clinical Implications.
- 2024-08-29
- Review
- Nutrients 16(17)
- - Christopher Sleiman
  - Rose-Mary Daou
  - Antonio Al Hazzouri
  - Zahi Hamdan
  - Hilda E Ghadieh
  - Bernard Harbieh
  - Maya Romani
- PubMed: 39275211
- DOI: 10.3390/nu16172895
1 Insight on
- Reduced Blood Pressure
- Moderate evidence
- Rigorous Journal
Lactobacillus acidophilus ameliorates cholestatic liver injury through inhibiting bile acid synthesis and promoting bile acid excretion.
- 2024-08-29
- RCT
- Gut microbes 16(1)
- - Lingyi Wu
  - Jianchun Zhou
  - An Zhou
  - Yuanyuan Lei
  - Li Tang
  - Shiping Hu
  - Sumin Wang
  - Xu Xiao
  - Qiao Chen
  - Dianji Tu
  - Cheng Lu
  - Yi Lai
  - Yiding Li
  - Xiao Zhang
  - Bo Tang
  - Shiming Yang
- PubMed: 39205654
- DOI: 10.1080/19490976.2024.2390176
1 Insight on
- Improved Liver Function
- High evidence
"Do probiotics mitigate GI-induced inflammation and perceived fatigue in athletes? A systematic review".
- 2024-08-28
- Systematic Review · n = 513
- Journal of the International Society of Sports Nutrition 21(1)
- - R P Kearns
  - J S G Dooley
  - M Matthews
  - A M McNeilly
- PubMed: 39193818
- DOI: 10.1080/15502783.2024.2388085
6 Insights on
- High evidence
An open label randomized controlled trial of the effects of rice bran oil on cardiometabolic risk factors, lipid peroxidation and antioxidant status in overweight/obese adults with metabolic syndrome.
- 2024-08-28
- RCT · n = 50
- Lipids in health and disease 23(1)
- - Marjan Mahdavi-Roshan
  - Nargeskhatoon Shoaibinobarian
  - Mehdi Evazalipour
  - Arsalan Salari
  - Zeinab Ghorbani
  - Amir Savarrakhsh
  - Zahra Ahmadnia
- PubMed: 39198792
- DOI: 10.1186/s12944-024-02260-4
16 Insights on
- High evidence
The Effect of Oral Colostrum Application on the Condition of the Mouth and Incidence of Late-Onset Sepsis Among Premature Infants: A Randomized Controlled Trial.
- 2024-08-27
- RCT
- Advances in neonatal care : official journal of the National Association of Neonatal Nurses 24(5)
- - Leila Barizeh
  - Mahnaz Jabraeili
  - Mohammad Bagher Hoseini
  - Mahni Rahkar Farshi
  - Julie-Anne Martyn
  - Deependra Kaji Thapa
  - Michelle Cleary
- PubMed: 39141690
- DOI: 10.1097/anc.0000000000001194
2 Insights on
- Reduced Incidence of Late-Onset Sepsis
- Reduced Need for Oral Care
- High evidence
The Effect of Swaddling and Oropharyngeal Colostrum During Endotracheal Suctioning on Procedural Pain and Comfort in Premature Neonates: A Randomized Controlled Trial.
- 2024-08-27
- RCT · n = 16
- Advances in neonatal care : official journal of the National Association of Neonatal Nurses 24(5)
- - Huriye Karadede
  - Birsen Mutlu
  - Birsen Mutlu
- PubMed: 39141691
- DOI: 10.1097/anc.0000000000001190
3 Insights on
- High evidence
The analgesic effect of curcumin and nano-curcumin in clinical and preclinical studies: a systematic review and meta-analysis.
- 2024-08-26
- Meta-Analysis
- Naunyn-Schmiedeberg's archives of pharmacology 398(1)
- - Pooya Hajimirzaei
  - Hossein Eyni
  - Maryam Razmgir
  - Sajad Abolfazli
  - Simin Pirzadeh
  - Faeze Sadat Ahmadi Tabatabaei
  - Ayda Vasigh
  - Nafiseh Yazdanian
  - Fatemeh Ramezani
  - Atousa Janzadeh
  - Alexandra E Butler
  - Amirhossein Sahebkar
- PubMed: 39186190
- DOI: 10.1007/s00210-024-03369-0
1 Insight on
- Reduced Pain
- High evidence
Topical Probiotic Hydrogels for Burn Wound Healing.
- 2024-08-23
- Review
- Gels (Basel, Switzerland) 10(9)
- - Tavinda Arshad
  - Varsha Mundrathi
  - Victoria E Perez
  - Jeilyn M Nunez
  - Hyunah Cho
- PubMed: 39330147
- DOI: 10.3390/gels10090545
1 Insight on
- Improved Wound Healing
- Low evidence
Protective Mechanisms of Vaginal Lactobacilli against Sexually Transmitted Viral Infections.
- 2024-08-23
- Review
- International journal of molecular sciences 25(17)
- - Elisa Avitabile
  - Laura Menotti
  - Vanessa Croatti
  - Barbara Giordani
  - Carola Parolin
  - Beatrice Vitali
- PubMed: 39273118
- DOI: 10.3390/ijms25179168
5 Insights on
- Moderate evidence
- Rigorous Journal
Probiotic Lactobacillus rhamnosus species: considerations for female reproduction and offspring health.
- 2024-08-22
- Review
- Journal of assisted reproduction and genetics 41(10)
- - Gizem Gamze Tas
  - Leyla Sati
- PubMed: 39172320
- DOI: 10.1007/s10815-024-03230-6
5 Insights on
- Low evidence
Probiotic applications of bifidobacteria in poultry: administration methods and microencapsulation techniques.
- 2024-08-22
- Review
- Microbiome research reports 4(3)
- - Eloy Argañaraz-Martínez
  - María Cristina Apella
  - Adriana Perez Chaia
  - Jaime Daniel Babot
- PubMed: 41133100
- DOI: 10.20517/mrr.2025.64
4 Insights on
- Low evidence
Targeting Divergent Pathways in the Nutritional Management of Depression.
- 2024-08-22
- Review
- Nutrients 16(16)
- - Derek Tobin
  - Alexander Vuckovic
  - Jerome Sarris
- PubMed: 39203943
- DOI: 10.3390/nu16162806
1 Insight on
- Reduced Depression Severity
- Moderate evidence
- Rigorous Journal
Pharmacological treatments for vascular dementia: a systematic review and Bayesian network meta-analysis.
- 2024-08-22
- Systematic Review · n = 194
- Frontiers in pharmacology 15
- - Chun Dang
  - Qinxuan Wang
  - Yijia Zhuang
  - Qian Li
  - Li Feng
  - Ying Xiong
  - Yaoheng Lu
- PubMed: 39239652
- DOI: 10.3389/fphar.2024.1451032
2 Insights on
- Improved Activities of Daily Living
- Improved Mini-Mental State Examination Score
- High evidence
Survival of Probiotic Bacterial Cells in the Upper Gastrointestinal Tract and the Effect of the Surviving Population on the Colonic Microbial Community Activity and Composition.
- 2024-08-21
- Nutrients 16(16)
- - Marlies Govaert
  - Chloë Rotsaert
  - Chelsea Vannieuwenhuyse
  - Cindy Duysburgh
  - Sophie Medlin
  - Massimo Marzorati
  - Harry Jarrett
- PubMed: 39203927
- DOI: 10.3390/nu16162791
1 Insight on
- Increased Probiotic Bacterial Survival Through Upper Gastrointestinal Transit
- Low evidence
- Rigorous Journal
Dual bacteriocin and extracellular vesicle-mediated inhibition of Campylobacter jejuni by the potential probiotic candidate Ligilactobacillus salivarius UO.C249.
- 2024-08-21
- Applied and environmental microbiology 90(8)
- - Mariem Chiba
  - Saba Miri
  - Basit Yousuf
  - Galal Ali Esmail
  - Luana Leao
  - Yingxi Li
  - Maxwell Hincke
  - Zoran Minic
  - Walid Mottawea
  - Riadh Hammami
- PubMed: 39078127
- DOI: 10.1128/aem.00845-24
2 Insights on
- Reduced Campylobacter jejuni Colonization/Growth
- Reduced Campylobacter jejuni Inhibition
- Low evidence
- Rigorous Journal
- Animal Study
Evaluation of efficacy and safety of Lacticaseibacillus rhamnosus LRa05 in the eradication of Helicobacter pylori: a randomized, double-blind, placebo-controlled trial.
- 2024-08-21
- RCT
- Frontiers in immunology 15
- - Yue Niu
  - Jing Li
  - Hongwei Qian
  - Chunli Liang
  - Xinyi Shi
  - Shurui Bu
- PubMed: 39234246
- DOI: 10.3389/fimmu.2024.1450414
12 Insights on
- High evidence
NAD+ and Niacin Supplementation as Possible Treatments for Glaucoma and Age-Related Macular Degeneration: A Narrative Review.
- 2024-08-21
- Review
- Nutrients 16(16)
- - Mohamed R Gemae
  - Mario D Bassi
  - Patrick Wang
  - Eric K Chin
  - David R P Almeida
- PubMed: 39203931
- DOI: 10.3390/nu16162795
4 Insights on
- Moderate evidence
- Rigorous Journal
Effects of Dietary Nitrate Supplementation on High-Intensity Cycling Sprint Performance in Recreationally Active Adults: A Systematic Review and Meta-Analysis.
- 2024-08-19
- Meta-Analysis
- Nutrients 16(16)
- - Rachel Tan
  - Jordan K Cass
  - Isabella G Lincoln
  - Lauren E Wideen
  - Madelyn J Nicholl
  - Trevor J Molnar
  - Lewis A Gough
  - Stephen J Bailey
  - Adam Pennell
- PubMed: 39203900
- DOI: 10.3390/nu16162764
4 Insights on
- High evidence
- Rigorous Journal
Pharmacological Treatment for Dialysis-Related Muscle Cramps: A Systematic Review.
- 2024-08-18
- Systematic Review · n = 4,660
- Seminars in dialysis 37(6)
- - Nidia Mantilla-Manosalva
  - Santiago Guadarrama
  - Lennis Jazmin Bedoya-Muñoz
  - Sara Giraldo-Moreno
  - Laura Cuellar-Valencia
  - María Fernanda Iriarte-Aristizábal
  - Marta Ximena León
  - Fernan Alejandro Mendoza-Montenegro
  - Juan Esteban Correa-Morales
- PubMed: 39155056
- DOI: 10.1111/sdi.13223
3 Insights on
- High evidence
Dietary Supplementation on Physical Performance and Recovery in Active-Duty Military Personnel: A Systematic Review of Randomized and Quasi-Experimental Controlled Trials.
- 2024-08-17
- Systematic Review
- Nutrients 16(16)
- - Jacie Harlow
  - Kylie Blodgett
  - Jenna Stedman
  - Rachele Pojednic
- PubMed: 39203882
- DOI: 10.3390/nu16162746
2 Insights on
- Improved Physical Performance
- Reduced Inflammatory Biomarker Level
- High evidence
- Rigorous Journal
Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
- 2024-08-16
- Meta-Analysis
- Journal of gastroenterology and hepatology 39(12)
- - Nicholas Ming-Zher Chee
  - Ram Prasad Sinnanaidu
  - Wah-Kheong Chan
- PubMed: 39150005
- DOI: 10.1111/jgh.16723
7 Insights on
- High evidence
Polyphenols in the Prevention and Treatment of Colorectal Cancer: A Systematic Review of Clinical Evidence.
- 2024-08-16
- Systematic Review · n = 100
- Nutrients 16(16)
- - Laura López-Gómez
  - Jose Antonio Uranga
- PubMed: 39203871
- DOI: 10.3390/nu16162735
5 Insights on
- High evidence
- Rigorous Journal
Effect of Saccharomyces boulardii on Liver Diseases: A Systematic Review.
- 2024-08-15
- Review
- Microorganisms 12(8)
- - Roman Maslennikov
  - Nona Benuni
  - Anna Levshina
  - Farida Adzhieva
  - Tatyana Demina
  - Alina Kucher
  - Ekaterina Pervushova
  - Evgeniya Yuryeva
  - Elena Poluektova
  - Oxana Zolnikova
  - Evgenii Kozlov
  - Alexey Sigidaev
  - Vladimir Ivashkin
- PubMed: 39203520
- DOI: 10.3390/microorganisms12081678
2 Insights on
- Reduced C-Reactive Protein Levels
- Reduced Child-Pugh Score
- Low evidence