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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Dietary administration of the probiotic, Saccharomyces cerevisiae P13, enhanced the growth, innate immune responses, and disease resistance of the grouper, Epinephelus coioides.
- 2010-12
- Clinical Trial
- Fish & Shellfish Immunology 29(6)
- - C. Chiu
  - Chih-Hsin Cheng
  - Wen-Ren Gua
  - Y. Guu
  - W. Cheng
- PubMed: 20816806
- DOI: 10.1016/j.fsi.2010.08.019
3 Insights on
- Low evidence
- Highly Cited
- Animal Study
Phase 2a Study Assessing Colonization Efficiency, Safety, and Acceptability of Lactobacillus crispatus CTV-05 in Women With Bacterial Vaginosis
- 2010-12
- RCT · n = 24
- Sexually Transmitted Diseases 37(12)
- - A. Hemmerling
  - William G. Harrison
  - A. Schroeder
  - Je-Bok Park
  - A. Korn
  - S. Shiboski
  - A. Foster-Rosales
  - C. Cohen
- PubMed: 20644497
- DOI: 10.1097/OLQ.0b013e3181e50026
11 Insights on
- High evidence
- Highly Cited
In vitro immunomodulatory activity of Lactobacillus fermentum CECT5716 and Lactobacillus salivarius CECT5713: two probiotic strains isolated from human breast milk.
- 2010-12
- Immunobiology 215(12)
- - F. Pérez-Cano
  - Honglin Dong
  - P. Yaqoob
- PubMed: 20219262
- DOI: 10.1016/j.imbio.2010.01.004
4 Insights on
- Low evidence
- Highly Cited
Lactobacillus plantarum consumption increases PepT1-mediated amino acid absorption by enhancing protein kinase C activity in spontaneously colitic mice.
- 2010-12
- Clinical Trial
- The Journal of Nutrition 140(12)
- - Hong-Qi Chen
  - T. Shen
  - Yu‐kun Zhou
  - Ming Zhang
  - Zhao-xin Chu
  - X. Hang
  - H. Qin
- PubMed: 20980636
- DOI: 10.3945/jn.110.123265
3 Insights on
- Low evidence
- Animal Study
Bifidobacterium bifidum reduces apoptosis in the intestinal epithelium in necrotizing enterocolitis.
- 2010-11
- Clinical Trial · n = 3
- American Journal of Physiology-Gastrointestinal and Liver Physiology 299(5)
- - L. Khailová
  - Sarah K Mount Patrick
  - Kelly M. Arganbright
  - M. Halpern
  - T. Kinouchi
  - B. Dvořák
- PubMed: 20705904
- DOI: 10.1152/ajpgi.00131.2010
2 Insights on
- Prevention of Necrotising Enterocolitis
- Reduced Intestinal Apoptosis
- Low evidence
- Highly Cited
- Animal Study
Human-derived probiotic Lactobacillus reuteri strains differentially reduce intestinal inflammation.
- 2010-11
- Clinical Trial
- American Journal of Physiology-Gastrointestinal and Liver Physiology 299(5)
- - Yuying Liu
  - Nicole Y. Fatheree
  - Nisha Mangalat
  - J. M. Rhoads
- PubMed: 20798357
- DOI: 10.1152/ajpgi.00124.2010
4 Insights on
- Low evidence
- Highly Cited
- Animal Study
Effect of probiotics enriched diet on Paralichthys olivaceus infected with lymphocystis disease virus (LCDV).
- 2010-11
- Clinical Trial
- Fish & Shellfish Immunology 29(5)
- - R. Harikrishnan
  - Chellam Balasundaram
  - M. Heo
- PubMed: 20688170
- DOI: 10.1016/j.fsi.2010.07.031
2 Insights on
- Improved Immune Response
- Enhanced Disease Resistance
- Low evidence
- Highly Cited
- Animal Study
Effects of a probiotic fermented milk beverage containing Lactobacillus casei strain Shirota on defecation frequency, intestinal microbiota, and the intestinal environment of healthy individuals with soft stools.
- 2010-11
- RCT
- Journal of Bioscience and Bioengineering 110(5)
- - Kazumasa Matsumoto
  - T. Takada
  - K. Shimizu
  - K. Moriyama
  - K. Kawakami
  - Koichi Hirano
  - O. Kajimoto
  - K. Nomoto
- PubMed: 20580604
- DOI: 10.1016/j.jbiosc.2010.05.016
5 Insights on
- High evidence
- Highly Cited
Probiotic applications of two dominant gut Bacillus strains with antagonistic activity improved the growth performance and immune responses of grouper Epinephelus coioides.
- 2010-11
- RCT
- Fish & Shellfish Immunology 29(5)
- - Yun‐Zhang Sun
  - Hong-Ling Yang
  - Ru-Long Ma
  - Wenhui Lin
- PubMed: 20637875
- DOI: 10.1016/j.fsi.2010.07.018
5 Insights on
- Low evidence
- Highly Cited
- Animal Study
Safety and tolerance of the human milk probiotic strain Lactobacillus salivarius CECT5713 in 6-month-old children.
- 2010-11
- RCT · n = 80
- Nutrition 26(11-12)
- - J. Maldonado
  - F. Lara‐Villoslada
  - S. Sierra
  - Lluis Sempere
  - Marta Gómez
  - J. M. Rodríguez
  - J. Boza
  - J. Xaus
  - M. Olivares
- PubMed: 20018483
- DOI: 10.1016/j.nut.2009.08.023
6 Insights on
- High evidence
- Highly Cited
Combined transcriptome and proteome analysis of Bifidobacterium animalis subsp. lactis BB-12 grown on xylo-oligosaccharides and a model of their utilization.
- 2010-11
- Applied and environmental microbiology 76(21)
- - Ofir Gilad
  - Susanne Jacobsen
  - Birgitte Stuer-Lauridsen
  - Martin Bastian Pedersen
  - Christel Garrigues
  - Birte Svensson
- PubMed: 20851982
- DOI: 10.1128/aem.00738-10
2 Insights on
- Increased Bifidobacteria Growth
- Enhanced Xylo-oligosaccharide Utilization
- Low evidence
- Rigorous Journal
Effects of Consumption of a Fermented Dairy Product Containing the Probiotic Lactobacillus casei DN-114 001 on Common Respiratory and Gastrointestinal Infections in Shift Workers in a Randomized Controlled Trial
- 2010-10
- RCT · n = 1,000
- Journal of the American College of Nutrition 29(5)
- - E. Guillemard
  - J. Tanguy
  - A. Flavigny
  - S. de la Motte
  - J. Schrezenmeir
- PubMed: 21504972
- DOI: 10.1080/07315724.2010.10719882
10 Insights on
- High evidence
- Large Human Trial
- Highly Cited
Complete Genome Sequence of Lactobacillus salivarius CECT 5713, a Probiotic Strain Isolated from Human Milk and Infant Feces
- 2010-10
- Journal of Bacteriology 192(19)
- - E. Jiménez
  - Rocío Martín
  - Antonio Maldonado
  - V. Martín
  - Aranzazu Gómez de Segura
  - L. Fernández
  - J. M. Rodríguez
- PubMed: 20675488
- DOI: 10.1128/JB.00703-10
6 Insights on
- Low evidence
Effects of Lactobacillus gasseri BNR17 on body weight and adipose tissue mass in diet-induced overweight rats
- 2010-10
- Clinical Trial
- The Journal of Microbiology 48(5)
- - Ji-hee Kang
  - S. Yun
  - Han-Oh Park
- PubMed: 21046354
- DOI: 10.1007/s12275-010-0363-8
3 Insights on
- Low evidence
- Highly Cited
- Animal Study
Invited review: Lactobacillus helveticus--a thermophilic dairy starter related to gut bacteria.
- 2010-10
- Journal of Dairy Science 93(10)
- - Lydia Slattery
  - John O'Callaghan
  - G. F. Fitzgerald
  - T. Beresford
  - R. Ross
- PubMed: 20854978
- DOI: 10.3168/jds.2010-3327
3 Insights on
- Low evidence
- Highly Cited
Lactobacillus reuteri (DSM 17938) in infants with functional chronic constipation: a double-blind, randomized, placebo-controlled study.
- 2010-10
- RCT · n = 44
- The Journal of Pediatrics 157(4)
- - P. Coccorullo
  - C. Strisciuglio
  - M. Martinelli
  - E. Miele
  - L. Greco
  - A. Staiano
- PubMed: 20542295
- DOI: 10.1016/j.jpeds.2010.04.066
5 Insights on
- High evidence
- Highly Cited
Effect of probiotic on growth performance and digestive enzyme activity of Arbor Acres broilers.
- 2010-10
- RCT · n = 30
- Research in Veterinary Science 89(2)
- - Yanbo Wang
  - Q. Gu
- PubMed: 20350733
- DOI: 10.1016/j.rvsc.2010.03.009
3 Insights on
- Low evidence
- Highly Cited
- Animal Study
Protective effects of Lactobacillus paracasei F19 in a rat model of oxidative and metabolic hepatic injury.
- 2010-09
- Clinical Trial · n = 27
- American Journal of Physiology-Gastrointestinal and Liver Physiology 299(3)
- - G. Nardone
  - D. Compare
  - E. Liguori
  - V. Di Mauro
  - A. Rocco
  - M. Barone
  - A. Napoli
  - D. Lapi
  - M. Iovene
  - A. Colantuoni
- PubMed: 20576921
- DOI: 10.1152/ajpgi.00188.2010
6 Insights on
- Low evidence
- Highly Cited
- Animal Study
Effects of Bifidobacterium lactis HN019 and Prebiotic Oligosaccharide Added to Milk on Iron Status, Anemia, and Growth Among Children 1 to 4 Years Old
- 2010-09
- RCT · n = 624
- Journal of Pediatric Gastroenterology and Nutrition 51(3)
- - S. Sazawal
  - U. Dhingra
  - Girish Hiremath
  - A. Sarkar
  - P. Dhingra
  - A. Dutta
  - V. Menon
  - R. Black
- PubMed: 20601905
- DOI: 10.1097/MPG.0b013e3181d98e45
3 Insights on
- High evidence
- Large Human Trial
Effect of intranasal administration of Lactobacillus pentosus S-PT84 on influenza virus infection in mice.
- 2010-09
- Clinical Trial
- International Immunopharmacology 10(9)
- - T. Izumo
  - Toshihiro Maekawa
  - M. Ida
  - A. Noguchi
  - Y. Kitagawa
  - H. Shibata
  - H. Yasui
  - Y. Kiso
- PubMed: 20601181
- DOI: 10.1016/j.intimp.2010.06.012
5 Insights on
- Low evidence
- Highly Cited
- Animal Study
The use of probiotics in healthy volunteers with evacuation disorders and hard stools: a double-blind, randomized, placebo-controlled study.
- 2010-09
- RCT · n = 110
- Journal of clinical gastroenterology 44(Supplement 1)
- - Mario Del Piano
  - Stefania Carmagnola
  - Andrea Anderloni
  - Silvano Andorno
  - Marco Ballarè
  - Marco Balzarini
  - Franco Montino
  - Marco Orsello
  - Michela Pagliarulo
  - Massimo Sartori
  - Roberto Tari
  - Filomena Sforza
  - Lucio Capurso
- PubMed: 20697291
- DOI: 10.1097/mcg.0b013e3181ee31c3
5 Insights on
- High evidence
- Large Human Trial
Hypocholesterolemic effect of sonication-killed Bifidobacterium longum isolated from healthy adult Koreans in high cholesterol fed rats
- 2010-09
- RCT · n = 24
- Archives of Pharmacal Research 33(9)
- - H. Shin
  - Shin‐Young Park
  - Do Kyung Lee
  - S. A. Kim
  - H. An
  - Jung Rae Kim
  - M. J. Kim
  - Min Gyeong Cha
  - S. Lee
  - Kyung Joo Kim
  - K. Lee
  - N. Ha
- PubMed: 20945142
- DOI: 10.1007/s12272-010-0917-7
13 Insights on
- Low evidence
- Highly Cited
- Animal Study
Lactic acid bacteria colonization and clinical outcome after probiotic supplementation in conventionally treated bacterial vaginosis and vulvovaginal candidiasis.
- 2010-09
- RCT · n = 95
- Microbes and Infection 12(10)
- - Sophia Ehrström
  - K. Daroczy
  - E. Rylander
  - C. Samuelsson
  - U. Johannesson
  - B. Anzén
  - C. Påhlson
- PubMed: 20472091
- DOI: 10.1016/j.micinf.2010.04.010
5 Insights on
- High evidence
- Highly Cited
Interaction of dietary Bacillus subtilis and fructooligosaccharide on the growth performance, non-specific immunity of sea cucumber, Apostichopus japonicus.
- 2010-08
- Fish & Shellfish Immunology 29(2)
- - Qin Zhang
  - Hongming Ma
  - K. Mai
  - Wenbing Zhang
  - Zhiguo Liufu
  - W. Xu
- PubMed: 20371291
- DOI: 10.1016/j.fsi.2010.03.009
8 Insights on
- Low evidence
- Highly Cited
Effect of Bifidobacterium animalis subsp lactis Supplementation in Preterm Infants: A Systematic Review of Randomized Controlled Trials
- 2010-08
- Systematic Review
- Journal of Pediatric Gastroenterology and Nutrition 51(2)
- - H. Szajewska
  - S. Guandalini
  - L. Morelli
  - J. V. van Goudoever
  - A. Walker
- PubMed: 20543719
- DOI: 10.1097/MPG.0b013e3181dc0d93
30 Insights on
- High evidence
Lactobacillus jensenii Surface-Associated Proteins Inhibit Neisseria gonorrhoeae Adherence to Epithelial Cells
- 2010-07
- Infection and Immunity 78(7)
- - R. Spurbeck
  - C. Arvidson
- PubMed: 20385752
- DOI: 10.1128/IAI.01200-09
1 Insight on
- Reduced Risk of Gonorrhea Infection
- Low evidence
- Highly Cited
Feed supplementation of Lactobacillus plantarum PCA 236 modulates gut microbiota and milk fatty acid composition in dairy goats--a preliminary study.
- 2010-07
- International Journal of Food Microbiology 141
- - P. Maragkoudakis
  - K. Mountzouris
  - C. Roșu
  - G. Zoumpopoulou
  - K. Papadimitriou
  - E. Dalaka
  - A. Hadjipetrou
  - Giorgos Theofanous
  - G. Strozzi
  - N. Carlini
  - G. Zervas
  - E. Tsakalidou
- PubMed: 20356645
- DOI: 10.1016/j.ijfoodmicro.2010.03.007
3 Insights on
- Low evidence
Intestinal and immunological effects of daily oral administration of Lactobacillus salivarius CECT5713 to healthy adults.
- 2010-06
- RCT · n = 40
- Anaerobe 16(3)
- - S. Sierra
  - F. Lara‐Villoslada
  - Lluis Sempere
  - M. Olivares
  - J. Boza
  - J. Xaus
- PubMed: 20159049
- DOI: 10.1016/j.anaerobe.2010.02.001
7 Insights on
- High evidence
- Highly Cited
Lactobacillus GG in the prevention of gastrointestinal and respiratory tract infections in children who attend day care centers: a randomized, double-blind, placebo-controlled trial.
- 2010-06
- RCT · n = 281
- Clinical Nutrition 29(3)
- - I. Hojsak
  - Natalija Snovak
  - S. Abdovic
  - H. Szajewska
  - Z. Mišak
  - S. Kolaček
- PubMed: 19896252
- DOI: 10.1016/j.clnu.2009.09.008
10 Insights on
- High evidence
- Highly Cited
Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier.
- 2010-06
- RCT
- American Journal of Physiology-Gastrointestinal and Liver Physiology 298(6)
- - J. Karczewski
  - F. Troost
  - I. Konings
  - J. Dekker
  - M. Kleerebezem
  - R. Brummer
  - J. Wells
- PubMed: 20224007
- DOI: 10.1152/ajpgi.00327.2009
9 Insights on
- High evidence
- Highly Cited