September 2018 Supplement Research Papers

• September 1

  • Efficacy of an Oral Rehydration Solution Enriched with Lactobacillus reuteri DSM 17938 and Zinc in the Management of Acute Diarrhoea in Infants: A Randomized, Double-Blind, Placebo-Controlled Trial

    • 2018-09-01
    • RCT · n = 51
    • Nutrients 10(9)
    • • M. Maragkoudaki
      • G. Chouliaras
      • A. Moutafi
      • A. Thomas
      • Archodoula Orfanakou
      • Alexandra Papadopoulou

    • PubMed: 30200394
    • DOI: 10.3390/nu10091189

    3 Insights on

    • Absence of Adverse Effects
    • Reduced Diarrhea Severity
    • Reduced Severity of Acute Diarrhoea

    • High evidence
• September 4

  • Using ruminally protected and nonprotected active dried yeast as alternatives to antibiotics in finishing beef steers: growth performance, carcass traits, blood metabolites, and fecal Escherichia coli.

    • 2018-09-04
    • RCT
    • Journal of Animal Science 96(10)
    • • T. Ran
      • Yizhao Shen
      • A. Saleem
      • O. Alzahal
      • K. Beauchemin
      • Wenzhu Z Yang

    • PubMed: 30184125
    • DOI: 10.1093/jas/sky272

    4 Insights on

    • Improved Liver Function
    • Reduced Fecal Escherichia coli Count
    • Increased Plasma Haptoglobin Levels
    • Reduced Serum Amyloid A Levels

    • High evidence

  • Killed Bifidobacterium longum enhanced stress tolerance and prolonged life span of Caenorhabditis elegans via DAF-16.

    • 2018-09-04
    • Clinical Trial
    • British Journal of Nutrition 120(8)
    • • Takaya Sugawara
      • K. Sakamoto

    • PubMed: 30178731
    • DOI: 10.1017/S0007114518001563

    3 Insights on

    • Extended Lifespan
    • Improved Environmental Stress Tolerance
    • Increased Mobility in Aging Worms

    • Low evidence
    • Animal Study
• September 10

  • The Lactobacillus casei Group: History and Health Related Applications

    • 2018-09-10
    • Frontiers in Microbiology 9
    • • Daragh Hill
      • Daragh Hill
      • Ivan Sugrue
      • Ivan Sugrue
      • Conor Tobin
      • Conor Tobin
      • Colin Hill
      • C. Stanton
      • R. Ross

    • PubMed: 30298055
    • DOI: 10.3389/fmicb.2018.02107

    8 Insights on

    • Reduced Disease Incidence
    • Enhanced Health Promotion
    • Disease Prevention
    • Improved Stress Response
    • Enhanced Health Promotion in Disease Management
    • Managed Gut Microbiota Disturbance
    • Improved Health Promotion
    • Enhanced Survival Under Stress

    • Low evidence
    • Highly Cited
• September 11

  • Lactobacillus plantarum C29‐Fermented Soybean (DW2009) Alleviates Memory Impairment in 5XFAD Transgenic Mice by Regulating Microglia Activation and Gut Microbiota Composition

    • 2018-09-11
    • Clinical Trial
    • Molecular Nutrition & Food Research 62(20)
    • • Hae-Ji Lee
      • Yun-Ha Hwang
      • Dong-Hyun Kim

    • PubMed: 30152045
    • DOI: 10.1002/mnfr.201800359

    5 Insights on

    • Improved Cognitive Function
    • Increased Serum BDNF Levels
    • Improved Gut Microbiome Composition
    • Reduced Amyloid-β Levels
    • Regulated Microglial Activation

    • Low evidence
    • Rigorous Journal
    • Animal Study
• September 14

  • Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms: a double-blind, randomised, placebo-controlled study.

    • 2018-09-14
    • RCT · n = 113
    • Beneficial Microbes 9(5)
    • • K. Preston
      • R. Krumian
      • J. Hattner
      • D. de Montigny
      • M. Stewart
      • S. Gaddam

    • PubMed: 29888656
    • DOI: 10.3920/BM2017.0105

    3 Insights on

    • Improved Quality of Life
    • Reduced Abdominal Pain
    • Reduced IBS Symptoms

    • High evidence

  • Exopolysaccharide from Bifidobacterium longum subsp. longum 35624™ modulates murine allergic airway responses.

    • 2018-09-14
    • Clinical Trial
    • Beneficial Microbes 9(5)
    • • Elisa Schiavi
      • Stephan Plattner
      • Noelia Rodriguez-Perez
      • Weronika Barcik
      • R. Frei
      • Ruth Ferstl
      • Magdalena Kurnik-Lucka
      • D. Groeger
      • R. Grant
      • Jennifer Roper
      • Friedrich Altmann
      • D. Sinderen
      • C. Akdis
      • Liam O'Mahony

    • PubMed: 29726281
    • DOI: 10.3920/BM2017.0180

    2 Insights on

    • Modulated Immune Response
    • Reduced Respiratory Inflammation Severity

    • Low evidence
    • Animal Study

  • Lactobacillus plantarum IS-10506 activates intestinal stem cells in a rodent model.

    • 2018-09-14
    • RCT · n = 64
    • Beneficial Microbes 9(5)
    • • A. F. Athiyyah
      • A. Darma
      • R. Ranuh
      • W. Riawan
      • A. Endaryanto
      • F. Rantam
      • I. Surono
      • S. Sudarmo

    • PubMed: 29726283
    • DOI: 10.3920/BM2017.0118

    6 Insights on

    • Reduced Inflammation
    • Increased Activation of Intestinal Stem Cells
    • Increased Lgr5 Levels in Intestinal Epithelium
    • Increased Bmi1 Levels in Intestinal Epithelial Cells
    • Elevated ERK Levels in Intestinal Stem Cells
    • Elevated β-Catenin Levels in Intestinal Stem Cells

    • Low evidence
    • Animal Study
• September 19

  • In vitro Probiotic Potential and Anti-cancer Activity of Newly Isolated Folate-Producing Streptococcus thermophilus Strains

    • 2018-09-19
    • Frontiers in Microbiology 9
    • • A. Tarrah
      • J. de Castilhos
      • R. Rossi
      • V. Duarte
      • D. Ziegler
      • V. Corich
      • A. Giacomini

    • PubMed: 30283428
    • DOI: 10.3389/fmicb.2018.02214

    6 Insights on

    • Improved Gut Microbiota
    • Increased Anticancer Activity
    • Enhanced Folate Synthesis
    • Reduced Cancer Activity
    • Enhanced Gut Health
    • Increased Folate Levels

    • Low evidence
• September 20

  • Whole Peptidoglycan Extracts from the Lactobacillus paracasei subsp. paracasei M5 Strain Exert Anticancer Activity In Vitro

    • 2018-09-20
    • BioMed Research International 2018
    • • Shumei Wang
      • Xue Han
      • Lanwei Zhang
      • Yingchun Zhang
      • Hongbo Li
      • Y. Jiao

    • PubMed: 29568745
    • DOI: 10.1155/2018/2871710

    1 Insight on

    • Induced Apoptosis

    • Low evidence
    • Rigorous Journal
• September 24

  • Effects of Bifidobacterium probiotic on the treatment of chronic periodontitis: A randomized clinical trial

    • 2018-09-24
    • RCT · n = 41
    • Journal of Clinical Periodontology 45(10)
    • • M. Invernici
      • S. Salvador
      • P. Silva
      • M. M. Soares
      • R. Casarin
      • D. Palioto
      • S. Souza
      • M. Taba
      • A. B. Novaes
      • F. Furlaneto
      • M. Messora

    • PubMed: 30076613
    • DOI: 10.1111/jcpe.12995

    7 Insights on

    • Reduced Pro-Inflammatory Cytokines
    • Reduced Pro-inflammatory Cytokine Levels
    • Reduced Probing Depth
    • Improved Clinical Attachment
    • Reduced Periodontal Pathogens
    • Increased B. lactis HN019 DNA Copies
    • Reduced Periodontal Pathogen Burden

    • High evidence
    • Highly Cited
    • Rigorous Journal

  • Effects of weight loss using supplementation with Lactobacillus strains on body fat and medium-chain acylcarnitines in overweight individuals.

    • 2018-09-24
    • RCT · n = 66
    • Food & Function 8(1)
    • • Minkyung Kim
      • Min-Joo Kim
      • Miso Kang
      • H. J. Yoo
      • Min Sun Kim
      • Y. Ahn
      • J. Sim
      • S. Jee
      • J. H. Lee

    • PubMed: 28001147
    • DOI: 10.1039/c6fo00993j

    5 Insights on

    • Reduced Body Weight
    • Reduced Subcutaneous Fat Mass
    • Reduced Body Fat
    • Reduced Body Fat Mass
    • Increased Medium-Chain Acylcarnitines

    • High evidence
• September 25

  • Prebiotic effects of resistant starch from purple yam (Dioscorea alata L.) on the tolerance and proliferation ability of Bifidobacterium adolescentis in vitro.

    • 2018-09-25
    • Food & Function 9(4)
    • • Tao Li
      • Lei Chen
      • Jianbo Xiao
      • Fengping An
      • C. Wan
      • Hongbo Song

    • PubMed: 29620784
    • DOI: 10.1039/c7fo01919j

    3 Insights on

    • Increased Short-Chain Fatty Acid Production
    • Improved Gastrointestinal Tolerance
    • Increased Bifidobacterium adolescentis Proliferation

    • Low evidence
• September 27

  • Effects of daily consumption of the probiotic Bifidobacterium animalis subsp. lactis CECT 8145 on anthropometric adiposity biomarkers in abdominally obese subjects: a randomized controlled trial

    • 2018-09-27
    • RCT · n = 125
    • International Journal of Obesity 43(9)
    • • A. Pedret
      • R. Valls
      • L. Calderón-Pérez
      • E. Llauradó
      • J. Companys
      • L. Pla-Pagà
      • A. Moragas
      • F. Martín-Luján
      • Y. Ortega
      • M. Giralt
      • A. Caimari
      • E. Chenoll
      • S. Genovés
      • P. Martorell
      • F. Codoñer
      • D. Ramón
      • L. Arola
      • R. Solà

    • PubMed: 30262813
    • DOI: 10.1038/s41366-018-0220-0

    11 Insights on

    • Reduced Diastolic Blood Pressure
    • Improved Insulin Sensitivity
    • Reduced Waist Circumference
    • Reduced Body Mass Index
    • Reduced Visceral Fat
    • Reduced Waist-to-Height Ratio
    • Reduced HOMA Index
    • Reduced Visceral Fat Mass
    • Reduced Visceral Fat Area
    • Improved Body Mass Index
    • Improved HOMA Index

    • High evidence
    • Highly Cited
• September 28

  • Effects of Lactococcus lactis subsp. lactis I2 with β-Glucooligosaccharides on Growth, Innate Immunity and Streptococcosis Resistance in Olive Flounder (Paralichthys olivaceus).

    • 2018-09-28
    • RCT · n = 2
    • Journal of Microbiology and Biotechnology 28(9)
    • • M. T. Hasan
      • W. Jang
      • Jin Yeong Tak
      • Bong-Joo Lee
      • K. Kim
      • Sang-woo Hur
      • Hyonsob Han
      • Bo-Seong Kim
      • Do-Huh Min
      • Shin-Kwon Kim
      • I. Kong

    • PubMed: 30176713
    • DOI: 10.4014/jmb.1805.05011

    13 Insights on

    • Reduced Pro-Inflammatory Cytokines
    • Improved Growth Performance
    • Improved Growth Rate
    • Enhanced Innate Immune Function
    • Improved Weight Gain
    • Increased Resistance to Group A Streptococcal Infections
    • Improved Viability of Lactic Acid Bacteria
    • Improved Innate Immunity
    • Enhanced Growth
    • Improved Intestinal LAB Viability
    • Elevated TNF-α Expression Level
    • Enhanced Protection Against Streptococcal Infection
    • Improved Streptococcal Resistance

    • Low evidence
    • Animal Study

  • Lactobacillus johnsonii CJLJ103 Attenuates Scopolamine-Induced Memory Impairment in Mice by Increasing BDNF Expression and Inhibiting NF-κB Activation.

    • 2018-09-28
    • Clinical Trial
    • Journal of Microbiology and Biotechnology 28(9)
    • • Hae-Ji Lee
      • Su-Min Lim
      • Dong-Hyun Kim

    • PubMed: 30111074
    • DOI: 10.4014/jmb.1805.05025

    2 Insights on

    • Enhanced Brain-Derived Neurotrophic Factor Levels
    • Improved Memory Function

    • Low evidence
    • Animal Study
• September 29

  • Antiviral potentials of Lactobacillus plantarum, Lactobacillus amylovorus, and Enterococcus hirae against selected Enterovirus.

    • 2018-09-29
    • Folia microbiologica 64(2)
    • • Abidemi Anota Sunmola
      • Omonike O Ogbole
      • Temitope O C Faleye
      • Adewale Adetoye
      • Johnson A Adeniji
      • Funmilola A Ayeni

    • PubMed: 30267215
    • DOI: 10.1007/s12223-018-0648-6

    2 Insights on

    • Reduced Enterovirus Replication
    • Reduced Enterovirus Infectivity

    • Low evidence
• Undated – 3 supplement studies

  • Dietary supplementation with Clostridium butyricum modulates serum lipid metabolism, meat quality, and the amino acid and fatty acid composition of Peking ducks

    • 2018-09
    • RCT · n = 1,500
    • Poultry Science 97(9)
    • • Yanhan Liu
      • Yiyu Li
      • Xiancheng Feng
      • Zhong Wang
      • Z. Xia

    • PubMed: 29762790
    • DOI: 10.3382/ps/pey162

    3 Insights on

    • Improved Lipid Metabolism
    • Improved Weight Gain
    • Enhanced Antioxidant Activity

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Comparative study of three predominant gut Bacillus strains and a commercial B. amyloliquefaciens as probiotics on the performance of Clarias gariepinus

    • 2018-09
    • RCT
    • Fish & Shellfish Immunology 80
    • • R. Reda
      • M. El-Hady
      • K. Selim
      • H. El-Sayed

    • PubMed: 29920384
    • DOI: 10.1016/j.fsi.2018.06.031

    5 Insights on

    • Improved Growth Performance
    • Enhanced Immune Function
    • Enhanced Hemogram Blood Parameters
    • Improved Immune Parameters
    • Improved Relative Survival Rate Against Pathogen

    • High evidence

  • Enterococcus faecium WEFA23 from infants lessens high-fat-diet-induced hyperlipidemia via cholesterol 7-alpha-hydroxylase gene by altering the composition of gut microbiota in rats.

    • 2018-09
    • Clinical Trial
    • Journal of Dairy Science 101(9)
    • • Fuqing Huang
      • Fen Zhang
      • Di Xu
      • Zhihong Zhang
      • Feng Xu
      • X. Tao
      • Liang Qiu
      • Hua Wei

    • PubMed: 29935822
    • DOI: 10.3168/jds.2017-13713

    5 Insights on

    • Improved Gut Microbiota Diversity
    • Reduced Total Cholesterol Levels
    • Reduced TMAO Production
    • Increased Bile Acid Synthesis
    • Reduced TMAO Levels

    • Low evidence
    • Rigorous Journal
    • Animal Study