May 2019 Supplement Research Papers

• May 4

  • Probiotics for paediatric functional abdominal pain disorders: A rapid review.

    • 2019-05-04
    • Review · n = 829
    • Paediatrics & child health 24(6)
    • • Fang Chao Linda Ding
      • Mohammad Karkhaneh
      • Liliane Zorzela
      • Hsing Jou
      • Sunita Vohra

    • PubMed: 31528110
    • DOI: 10.1093/pch/pxz036

    1 Insight on

    • Reduced Abdominal Pain

    • High evidence
• May 6

  • Clostridium butyricum Strains Suppress Experimental Acute Pancreatitis by Maintaining Intestinal Homeostasis.

    • 2019-05-06
    • Clinical Trial
    • Molecular Nutrition & Food Research 63(13)
    • • Li-Long Pan
      • Wenying Niu
      • X. Fang
      • Wenjie Liang
      • Hongli Li
      • Wei Chen
      • Hao Zhang
      • M. Bhatia
      • Jia Sun

    • PubMed: 31034143
    • DOI: 10.1002/mnfr.201801419

    3 Insights on

    • Increased Abundance of Beneficial Microbes
    • Improved Gut Microbial Dysbiosis
    • Reduced Pancreatic Bacterial Penetration

    • Low evidence
    • Animal Study
• May 8

  • Local Probiotic Lactobacillus crispatus and Lactobacillus delbrueckii Exhibit Strong Antifungal Effects Against Vulvovaginal Candidiasis in a Rat Model

    • 2019-05-08
    • Clinical Trial
    • Frontiers in Microbiology 10
    • • Ting Li
      • Zhaohui Liu
      • Xu Zhang
      • Xi Chen
      • Su-xia Wang

    • PubMed: 31139166
    • DOI: 10.3389/fmicb.2019.01033

    10 Insights on

    • Reduced Pro-inflammatory Cytokine Release
    • Reduced Candida Counts
    • Reduced Candida albicans Colony-Forming Units
    • Maintained Immune Homeostasis
    • Improved Immune Homeostasis
    • Reduced Candida Albicans Infection
    • Increased Epithelial-Derived IgG Levels
    • Reduced Vaginal Candidiasis Symptoms
    • Reduced Th1/Th2 Ratio (IFN-γ/IL-4)
    • Reduced Th1/Th2 Ratio

    • Low evidence
    • Animal Study
• May 11

  • Synergetic Effects of Lactobacillus plantarum and β-Glucan on Digestive Enzyme Activity, Intestinal Morphology, Growth, Fatty Acid, and Glucose-Related Gene Expression of Genetically Improved Farmed Tilapia

    • 2019-05-11
    • RCT
    • Probiotics and Antimicrobial Proteins 12(2)
    • • M. Dawood
      • F. Magouz
      • M. Salem
      • Z. Elbialy
      • Hanaa A Abdel-Daim

    • PubMed: 31077008
    • DOI: 10.1007/s12602-019-09552-7

    1 Insight on

    • Improved Intestinal Morphology

    • Low evidence
    • Animal Study
• May 14

  • Severity of Candida-associated denture stomatitis is improved in institutionalized elders who consume Lactobacillus rhamnosus SP1.

    • 2019-05-14
    • RCT · n = 36
    • Australian Dental Journal 64(3)
    • • X. Lee
      • C. Vergara
      • C. Lozano

    • PubMed: 30963591
    • DOI: 10.1111/adj.12692

    1 Insight on

    • Reduced Severity of Denture Stomatitis

    • High evidence
• May 15

  • Lactobacillus reuteri DSM 17938—A comparative study on the effect of probiotics and lysates on human skin

    • 2019-05-15
    • Experimental Dermatology 28(7)
    • • Ia Khmaladze
      • Éile Butler
      • Susanne Fabre
      • J. Gillbro

    • PubMed: 31021014
    • DOI: 10.1111/exd.13950

    2 Insights on

    • Reduced Inflammation Levels
    • Improved Skin Barrier Function

    • Low evidence
• May 16

  • Effect of ingesting yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 on influenza virus-bound salivary IgA in elderly residents of nursing homes: a randomized controlled trial

    • 2019-05-16
    • RCT · n = 96
    • Acta Odontologica Scandinavica 77(7)
    • • Yuko Yamamoto
      • J. Saruta
      • Toru Takahashi
      • M. To
      • Tomoko Shimizu
      • Takashi Hayashi
      • T. Morozumi
      • N. Kubota
      • Yohei Kamata
      • Seiya Makino
      • H. Kano
      • Jun Hemmi
      • Y. Asami
      • T. Nagai
      • K. Misawa
      • Sachiko Kato
      • K. Tsukinoki

    • PubMed: 31094267
    • DOI: 10.1080/00016357.2019.1609697

    6 Insights on

    • Increased Salivary IgA Levels for Influenza A Virus H3N2
    • Increased Salivary sIgA Levels
    • Increased Salivary IgA Levels
    • Increased Saliva Production
    • Increased Salivary Influenza Virus-Bound IgA
    • Increased Total Immunoglobulin A (IgA) Levels

    • High evidence
• May 21

  • Lactobacillus plantarum NA136 improves the non-alcoholic fatty liver disease by modulating the AMPK/Nrf2 pathway

    • 2019-05-21
    • Clinical Trial
    • Applied Microbiology and Biotechnology 103(14)
    • • Zijian Zhao
      • Chao Wang
      • Li Zhang
      • Yujuan Zhao
      • Cui-cui Duan
      • Xue Zhang
      • Lei Gao
      • Shengyu Li

    • PubMed: 31115630
    • DOI: 10.1007/s00253-019-09703-4

    8 Insights on

    • Increased Antioxidant Activity
    • Reduced Blood Lipid Levels
    • Reduced Body Weight Gain
    • Reduced Fat Mass
    • Reduced AST Levels
    • Reduced De Novo Lipogenesis
    • Improved Fatty Acid Oxidation
    • Reduced ALT Level

    • Low evidence
    • Animal Study
• May 23

  • Intraluminal Impact of Food: New Insights from MRI.

    • 2019-05-23
    • Review
    • Nutrients 11(5)
    • • Robin Spiller
      • Luca Marciani

    • PubMed: 31126027
    • DOI: 10.3390/nu11051147

    1 Insight on

    • Increased Colonic Water Content

    • Moderate evidence
    • Rigorous Journal
• May 25

  • Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the "SERENA study", a randomized, double-blind, placebo-controlled trial.

    • 2019-05-25
    • RCT
    • Endocrine 66(3)
    • • G Mantovani
      • A M Isidori
      • C Moretti
      • C Di Dato
      • E Greco
      • P Ciolli
      • M Bonomi
      • L Petrone
      • A Fumarola
      • G Campagna
      • G Vannucchi
      • S Di Sante
      • C Pozza
      • A Faggiano
      • A Lenzi
      • E Giannetta

    • PubMed: 31129812
    • DOI: 10.1007/s12020-019-01958-1

    11 Insights on

    • Improved Quality of Life
    • Reduced Thyroid Peroxidase Antibody Level
    • Reduced Thyroglobulin Antibody Level
    • Reduced Thyroid Volume
    • Increased Selenium Level
    • Improved Thyroid Echogenicity
    • Reduced Thyroid Echogenicity
    • Reduced Maternal Complication
    • Reduced Maternal-Fetal Complications
    • Increased Selenium Status
    • Reduced Fetal Complication

    • High evidence

  • Leuconostoc mesenteroides subsp. mesenteroides SD23 Prevents Metabolic Dysfunction Associated with High-Fat Diet–Induced Obesity in Male Mice

    • 2019-05-25
    • RCT
    • Probiotics and Antimicrobial Proteins 12(2)
    • • D. Castro-Rodríguez
      • L. Reyes-Castro
      • C. Vega
      • G. L. Rodríguez-González
      • J. Yáñez-Fernández
      • E. Zambrano

    • PubMed: 31129870
    • DOI: 10.1007/s12602-019-09556-3

    8 Insights on

    • Reduced Total Cholesterol Levels
    • Reduced Leptin Levels
    • Reduced Body Weight
    • Increased Interleukin-10 Levels
    • Improved Glucose Tolerance
    • Reduced Adipocyte Size
    • Reduced Liver Fat
    • Reduced Villus Height

    • Low evidence
    • Animal Study

  • Glucose Tolerance Test and Pharmacokinetic Study of Kaempferia parviflora Extract in Healthy Subjects.

    • 2019-05-25
    • RCT
    • Nutrients 11(5)
    • • Bungorn Sripanidkulchai
      • Catheleeya Mekjaruskul
      • Rosawan Areemit
      • Areewan Cheawchanwattana
      • Jiraporn Sithithaworn

    • PubMed: 31130666
    • DOI: 10.3390/nu11051176

    1 Insight on

    • Improved Glucose Tolerance

    • High evidence
    • Rigorous Journal
• May 28

  • Effects of Bifidobacterium breve A1 on the cognitive function of older adults with memory complaints: a randomised, double-blind, placebo-controlled trial.

    • 2019-05-28
    • RCT · n = 121
    • Beneficial Microbes 10(5)
    • • Y. Kobayashi
      • T. Kuhara
      • M. Oki
      • J.‐Z. Xiao

    • PubMed: 31090457
    • DOI: 10.3920/BM2018.0170

    9 Insights on

    • Improved Cognitive Function
    • Safety of Probiotic Supplementation
    • No Adverse Health Effects
    • Maintained Cognitive Function
    • Improved Immediate Memory
    • No Significant Cognitive Improvement
    • Maintained or Improved Cognitive Function
    • Improved MMSE Score
    • No Difference in Overall Cognitive Scores

    • High evidence
    • Highly Cited

  • Three probiotic strains exert different effects on plasma bile acid profiles in healthy obese adults: randomised, double-blind placebo-controlled crossover study.

    • 2019-05-28
    • RCT · n = 57
    • Beneficial microbes 10(5)
    • • T Culpepper
      • C C Rowe
      • C T Rusch
      • A M Burns
      • A P Federico
      • S-A Girard
      • T A Tompkins
      • C Nieves
      • J C Dennis-Wall
      • M C Christman
      • B Langkamp-Henken

    • PubMed: 31090458
    • DOI: 10.3920/bm2018.0151

    5 Insights on

    • Reduced Total Cholesterol Levels
    • Improved Insulin Levels
    • Reduced Blood Glucose Levels
    • Increased Fecal Bile Acid Levels
    • Reduced Serum Lipid Levels

    • High evidence
    • Rigorous Journal

  • Impact of oral administration of four Lactobacillus strains on Nugent score - systematic review and meta-analysis.

    • 2019-05-28
    • Meta-Analysis · n = 36
    • Beneficial microbes 10(5)
    • • M de Vrese
      • C Laue
      • E Papazova
      • L Petricevic
      • J Schrezenmeir

    • PubMed: 31012733
    • DOI: 10.3920/bm2018.0129

    1 Insight on

    • Improved Vaginal Microbiota

    • High evidence
    • Rigorous Journal

  • Impact of oral administration of four Lactobacillus strains on Nugent score - systematic review and meta-analysis.

    • 2019-05-28
    • Meta-Analysis
    • Beneficial Microbes 10(5)
    • • M. Vrese
      • C. Laue
      • E. Papazova
      • L. Petricevic
      • Juergen Schrezenmeir

    • PubMed: 31012733
    • DOI: 10.3920/BM2018.0129

    4 Insights on

    • Improved Vaginal Microbiota Balance
    • Reduced Nugent Score
    • Improved Nugent Score
    • Improved Vaginal Microbiota

    • High evidence
• May 31

  • Vaginal lactobacilli inhibit growth and hyphae formation of Candida albicans

    • 2019-05-31
    • Scientific Reports 9(1)
    • • Sung Jae Jang
      • Kyeong-Sik Lee
      • Bomi Kwon
      • H. You
      • Gwangpyo Ko

    • PubMed: 31148560
    • DOI: 10.1038/s41598-019-44579-4

    3 Insights on

    • Reduced Candida albicans Growth
    • Reduced Candida Albicans Hyphal Formation
    • Reduced Candida Albicans Propagation In Vivo

    • Low evidence
    • Rigorous Journal

  • Oral probiotics reduce halitosis in patients wearing orthodontic braces: a randomized, triple-blind, placebo-controlled trial

    • 2019-05-31
    • RCT · n = 64
    • Journal of Breath Research 13(3)
    • • Gareth Benic
      • M. Farella
      • X. Morgan
      • Jay P. Viswam
      • N. Heng
      • R. Cannon
      • L. Mei

    • PubMed: 31022704
    • DOI: 10.1088/1752-7163/ab1c81

    3 Insights on

    • Reduced Halitosis
    • Improved Oral Health
    • Reduced Plaque Index

    • High evidence
• Undated – 6 supplement studies

  • Enhanced mucosal immune responses, immune related genes and growth performance in common carp (Cyprinus carpio) juveniles fed dietary Pediococcus acidilactici MA18/5M and raffinose

    • 2019-05
    • RCT
    • Developmental & Comparative Immunology 94
    • • S. Hoseinifar
      • Marjan Hosseini
      • H. Paknejad
      • R. Safari
      • A. Jafar
      • M. Yousefi
      • Hien Van Doan
      • Mansour Torfi Mozanzadeh

    • PubMed: 30668960
    • DOI: 10.1016/j.dci.2019.01.009

    2 Insights on

    • Improved Growth Performance
    • Enhanced Skin Mucus Protease Activity

    • Low evidence
    • Animal Study

  • Herbal Medicinal Product Use During Pregnancy and the Postnatal Period: A Systematic Review.

    • 2019-05
    • Systematic Review · n = 71
    • Obstetrics and gynecology 133(5)
    • • Yolanda Muñoz Balbontín
      • Derek Stewart
      • Ashalatha Shetty
      • Catherine A Fitton
      • James S McLay

    • PubMed: 30969204
    • DOI: 10.1097/aog.0000000000003217

    2 Insights on

    • Reduced Cesarean Delivery
    • Reduced Early Preterm Birth

    • High evidence

  • Beyond tribulus (Tribulus terrestris L.): The effects of phytotherapics on testosterone, sperm and prostate parameters.

    • 2019-05
    • Review
    • Journal of ethnopharmacology 235
    • • Heitor O Santos
      • Scott Howell
      • Filipe J Teixeira

    • PubMed: 30790614
    • DOI: 10.1016/j.jep.2019.02.033

    3 Insights on

    • Increased Total Testosterone
    • Improved Sperm Quality
    • Improved Prostate Health

    • Low evidence

  • Glycaemic regulation, appetite and ex vivo oxidative stress in young adults following consumption of high-carbohydrate cereal bars fortified with polyphenol-rich berries.

    • 2019-05
    • RCT
    • The British journal of nutrition 121(09)
    • • Tracey J Smith
      • James Philip Karl
      • Marques A Wilson
      • Claire C Whitney
      • Ann Barrett
      • Nicole Favreau Farhadi
      • Chung-Yen Oliver Chen
      • Scott J Montain

    • PubMed: 31062684
    • DOI: 10.1017/s0007114519000394

    6 Insights on

    • Reduced Appetite
    • Reduced Postprandial Glucose
    • Reduced Postprandial Insulin
    • Reduced Glucose-Dependent Insulinotropic Polypeptide Level
    • Reduced C-Peptide Level
    • Reduced Appetite-Mediating Hormone Level

    • High evidence

  • Snack selection influences glucose metabolism, antioxidant capacity and cholesterol in healthy overweight adults: A randomized parallel arm trial.

    • 2019-05
    • RCT
    • Nutrition research (New York, N.Y.) 65
    • • Zachary S Clayton
      • Elizabeth Fusco
      • Lisa Schreiber
      • Jennifer N Carpenter
      • Shirin Hooshmand
      • Mee Young Hong
      • Mark Kern

    • PubMed: 30952505
    • DOI: 10.1016/j.nutres.2019.03.002

    21 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Waist Circumference
    • Reduced Low-Density Lipoprotein Level
    • Reduced Systolic Blood Pressure
    • Reduced Body Weight
    • Reduced Blood Pressure
    • Reduced Triglyceride Levels
    • Improved Insulin Levels
    • Increased Adiponectin Levels
    • Reduced LDL Cholesterol
    • Reduced Body Fat
    • Reduced Insulin Levels
    • Reduced Inflammation
    • Reduced Blood Cholesterol
    • Reduced Fasting Blood Glucose Levels
    • Increased Total Serum Antioxidant Capacity
    • Increased High-Density Lipoprotein Cholesterol
    • Reduced Postprandial Glycemia
    • Increased Dietary Fiber Intake
    • Reduced Adipokine Level
    • Increased Potassium Level

    • High evidence

  • Effectiveness of black tea versus placebo in subjects with hypercholesterolemia: A PRISMA systematic review and meta-analysis.

    • 2019-05
    • Meta-Analysis
    • Diabetes & metabolic syndrome 13(3)
    • • Felipe Araya-Quintanilla
      • Héctor Gutiérrez-Espinoza
      • Valeria Moyano-Gálvez
      • María Jesús Muñoz-Yánez
      • Leonardo Pavez
      • Katherine García

    • PubMed: 31235165
    • DOI: 10.1016/j.dsx.2019.05.019

    4 Insights on

    • Reduced Low-Density Lipoprotein Level
    • Reduced Triglyceride Levels
    • Increased HDL Cholesterol Levels
    • Reduced Blood Cholesterol

    • High evidence