Assimilation of cholesterol by Lactobacillus acidophilus1985-02Applied and Environmental Microbiology 49(2)S. GillilandC. R. NelsonC. MaxwellPubMed: 3920964DOI: 10.1128/aem.49.2.377-381.19852 Insights on Reduced Serum CholesterolReduced Serum Total Cholesterol Levels
A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial.2020-05Digestive and Liver Disease 52(5)S. SadrinS. SennouneB. GoutS. MarqueJ. MoreauKarim ZinouneJ. GrillascaO. PonsJ. MaixentPubMed: 31952938DOI: 10.1016/j.dld.2019.12.00914 Insights on Improved Gastrointestinal SymptomsImproved Gastrointestinal ScoreImproved Composite Symptom ScoreReduced Abdominal PainImproved Gastrointestinal Symptom ScoreImproved Composite Score of Irritable Bowel Syndrome SymptomsImproved FlatusImproved Abdominal PainDecreased Composite ScoresReduced Composite ScoreReduced Composite Symptom ScoreReduced FlatulenceReduced Abdominal Pain SeverityImproved IBS Composite Symptom Score
Lactobacillus acidophilus and L. plantarum improve health status, modulate gut microbiota and innate immune response of marron (Cherax cainii)2020-04-03Scientific Reports 10(1)Md Javed FoysalR. FotedarM. SiddikA. TayPubMed: 32246011DOI: 10.1038/s41598-020-62655-y12 Insights on Increased Gut Microvilli CountsImproved Intestinal Microbial CompositionEnhanced Innate Immune FunctionImproved Hepatopancreas HealthImproved Microbial Community CompositionAltered Gut Microbiota CompositionChange in Vaginal Microbiota CompositionIncreased Gut Microvilli CountImproved Muscle Biochemical CompositionImproved Hemolymph ParametersAltered Gut Microbial CommunityImproved Gut Microbiota Composition
Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults—Randomized Controlled Trial☆☆☆2016-11EBioMedicine 13L. StenmanM. LehtinenN. MelandJ. ChristensenNicolas YeungM. SaarinenM. CourtneyR. BurcelinM. LähdeahoJüri LinrosD. ApterM. ScheininH. Kloster SmerudA. RissanenS. LahtinenPubMed: 27810310DOI: 10.1016/j.ebiom.2016.10.0363 Insights on Reduced Body Fat MassReduced Food IntakeReduced Waist Circumference
Molecular analysis of yogurt containing Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus in human intestinal microbiota.2008-01The American Journal of Clinical Nutrition 87(1)Raimundo García-AlbiachMaría José Pozuelo de FelipeSantiago AnguloM. MorosiniD. BravoF. BaqueroR. del CampoPubMed: 18175741DOI: 10.1093/AJCN/87.1.913 Insights on Increased Clostridium perfringens DensityIncreased Lactobacillus Acidophilus LevelsReduced Bacteroides Expression
Lactobacillus bulgaricus, Lactobacillus rhamnosus and Lactobacillus paracasei Attenuate Salmonella Enteritidis, Salmonella Heidelberg and Salmonella Typhimurium Colonization and Virulence Gene Expression In Vitro2017-11-09International Journal of Molecular Sciences 18(11)M. S. MuyyarikkandyM. AmalaradjouPubMed: 29120368DOI: 10.3390/ijms181123812 Insights on Reduced Salmonella ColonizationReduced Virulence Gene Expression
Enriched selenium and its effects on growth and biochemical composition in Lactobacillus bulgaricus.2007-02-17Journal of Agricultural and Food Chemistry 55(6)S. XiaLong ChenJun LiangPubMed: 17305360DOI: 10.1021/JF062946J2 Insights on Enhanced Nutrient CompositionIncreased Selenium Absorption
Effect of perorally administered lactobacilli on macrophage activation in mice1986-08Infection and Immunity 53(2)G. PerdigónMaria Elena NaderDeMacias'. S. Alvarez'. G. OliverAida A. PesceRuiz HolgadoPubMed: 3733223DOI: 10.1128/iai.53.2.404-410.19862 Insights on Enhanced Macrophage ActivationImproved Phagocytic Activity
Immunomodulatory effects of polysaccharides produced by Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1.2006-08Journal of Dairy Science 89(8)Seiya MakinoShuji IkegamiHiroshi KanoT. SashiharaH. SuganoH. HoriuchiTadao SaitoM. OdaPubMed: 16840603DOI: 10.3168/JDS.S0022-0302(06)72560-73 Insights on Increased NK Cell ActivityEnhanced Interferon Gamma ProductionImproved Immunomodulation
Lactobacillus delbrueckii subsp. bulgaricus KLDS 1.0207 Exerts Antimicrobial and Cytotoxic Effects in vitro and Improves Blood Biochemical Parameters in vivo Against Notable Foodborne Pathogens2020-09-24Frontiers in Microbiology 11S. EvivieAmro AbdelazezBailiang LiShi-juan LuFei LiuG. HuoPubMed: 33072056DOI: 10.3389/fmicb.2020.58307015 Insights on Improved HDL Cholesterol LevelsPrevention of Weight LossReduced Pathogen GrowthImproved Cholesterol RegulationImproved Biochemical ParametersImproved Weight ManagementReduced Pathogen ActivityNormalized Serum Lipid LevelsSurvival in Simulated Gastric ConditionsImproved Lipid LevelsRestored HDL LevelsIncreased Survival in Acidic EnvironmentReduced Inflammatory ActivitiesEnhanced Viability in Acidic ConditionsReduced Inflammation Levels
Lactobacillus bulgaricus or Lactobacillus rhamnosus Suppresses NF-κB Signaling Pathway and Protects against AFB1-Induced Hepatitis: A Novel Potential Preventive Strategy for Aflatoxicosis?2019-01-04Toxins 11(1)Yuanyuan ChenRuirui LiQiaocheng ChangZhihao DongHuanmin YangChuang XuPubMed: 30621122DOI: 10.3390/toxins110100175 Insights on Prevented Liver InjuryLiver Protection from Aflatoxin B1 DamageReduced Liver InflammationReduced Inflammatory ResponseReduced AFB1-Induced Liver Damage
A novel Lactobacillus bulgaricus isolate can maintain the intestinal health, improve the growth performance and reduce the colonization of E. coli O157:H7 in broilers2022-05-11British Poultry Science 63(5)L. XiangZ. YingM. XueP. XiaoxianL. XiaorongL. ChunyangW. YuL. MingchengL. BinxianPubMed: 35383527DOI: 10.1080/00071668.2022.206222010 Insights on Improved Intestinal Microflora DiversityReduced E. coli O157:H7 Content in CaecumImproved Intestinal FunctionIncreased Villus Height to Crypt Depth RatioReduced Inflammatory MarkersImproved Growth PerformanceImproved Feed Conversion RatioImproved Gastrointestinal HealthReduced Inflammatory ResponseReduced E. coli O157:H7 Colonization
Effect of Encapsulated Lactobacillus bulgaricus on Innate Immune System and Hematological Parameters in Rainbow Trout (Oncorhynchus mykiss), Post-Administration of Pb2019-04-25Probiotics and Antimicrobial Proteins 12(2)T. MohammadianZ. T. DezfulyReza Ghanei MotlaghA. Jangaran-NejadS. S. HosseiniH. KhajN. AlijaniPubMed: 31025260DOI: 10.1007/s12602-019-09544-714 Insights on Reduced White Blood Cells After Lead ExposureEnhanced Bactericidal ActivityReduced Heavy Metal ToxicityEnhanced Complement Pathway ActivityIncreased Hemoglobin LevelsReduced Blood Parameters Post Lead ExposureIncreased White Blood Cell CountIncreased Red Blood Cell CountReduced Respiratory Burst ActivityIncreased Respiratory Burst ActivityReduced Red Blood Cell CountIncreased Serum Lysozyme ActivityReduced Hemoglobin LevelReduced Toxicity
New immunobiotics from highly proteolytic Lactobacillus delbrueckii strains: their impact on intestinal antiviral innate immune response.2020-08-12Beneficial Microbes 11(4)M. EleanL. AlbarracínP. G. CataldoA. LonderoH. KitazawaL. SaavedraJ. VillenaE. HebertPubMed: 32755264DOI: 10.3920/bm2019.01988 Insights on Enhanced Activation of Peritoneal MacrophagesIncreased Intestinal IgA LevelsReduced Intestinal InflammationElevated Interleukin-10 LevelsReduced Tumor Necrosis Factor AlphaIncreased Interferon-Gamma LevelsElevated Interferon-β LevelsReduced Interleukin-6 Levels
Survival of Lactobacillus delbrueckii UFV H2b20 in fermented milk under simulated gastric and intestinal conditions.2013-09-01Beneficial Microbes 4(3)L. L. da ConceiçãoE. S. LeandroF. S. FreitasM. N. V. de OliveiraA. B. Ferreira-MachadoA. C. BorgesC. A. de MoraesPubMed: 23685374DOI: 10.3920/BM2013.00031 Insight on Improved Probiotic Viability
In vitro studies of Lactobacillus delbrueckii subsp. lactis in Atlantic salmon (Salmo salar L.) foregut: tissue responses and evidence of protection against Aeromonas salmonicida subsp. salmonicida epithelial damage.2008-04Veterinary Microbiology 128(1-2)I. SalinasR. MyklebustM. EstebanR. OlsenJ. MeseguerE. RingøPubMed: 18054448DOI: 10.1016/J.VETMIC.2007.10.0115 Insights on Improved Epithelial ProtectionMaintained Intestinal Barrier FunctionEnterocyte Surface ColonizationProtection Against Cellular Damage Induced by PathogensImproved Intestinal Barrier Integrity
Lactobacillus delbrueckii subsp lactis CIDCA 133 modulates response of human epithelial and dendritic cells infected with Bacillus cereus.2016-11-30Beneficial Microbes 7(5)I. RolnyI. TiscorniaS. RacedoP. PerezM. Bollati-FogolínPubMed: 27459335DOI: 10.3920/BM2015.01913 Insights on Reduced Bacterial TranslocationIncreased Tumor Necrosis Factor-Alpha Production by Dendritic CellsReduced IL-8 Production
Lactobacillus delbrueckii Interfere With Bile Acid Enterohepatic Circulation to Regulate Cholesterol Metabolism of Growing–Finishing Pigs via Its Bile Salt Hydrolase Activity2020-12-11Frontiers in Nutrition 7G. HouWei PengLiangkai WeiRui LiYong YuanXingguo HuangYulong YinPubMed: 33363199DOI: 10.3389/fnut.2020.6176763 Insights on Reduced Serum Total Cholesterol LevelsIncreased Fecal Cholesterol ExcretionReduced Serum Triglyceride Levels
β-Casein hydrolysate generated by the cell envelope-associated proteinase of Lactobacillus delbrueckii ssp. lactis CRL 581 protects against trinitrobenzene sulfonic acid-induced colitis in mice.2012-03Journal of Dairy Science 95(3)M. B. E. TurbayA. LeBlancG. PerdigónG. S. D. GioriE. HebertPubMed: 22365194DOI: 10.3168/jds.2011-473514 Insights on Reduced Colonic Microscopic DamageReduced Beta-Glucuronidase ActivityReduced Gut IFN-γ ProductionReduced Interferon-Gamma ProductionReduced Microbial TranslocationReduced Myeloperoxidase ActivityIncreased Interleukin-10 Production in the GutReduced Colonic Oxidative DamageFaster Recovery of Body WeightIncreased IL-10 ProductionAccelerated Weight Loss RecoveryReduced Microbial Translocation to the LiverImproved Macroscopic Colonic DamageReduced Mortality Rate
Soymilk-fermented with Lactobacillus delbrueckii subsp. delbrueckii TUA4408L improves immune-health in pigs.2022-02-28Beneficial Microbes 13(1)Y. SudaK. KagawaK. FukuyamaM. EleanB. ZhouM. TomokiyoM. A. IslamM. RajokaA. KoberT. ShimazuS. EgusaY. TerashimaH. AsoW. Ikeda-OhtsuboJ. VillenaH. KitazawaPubMed: 35098908DOI: 10.3920/BM2021.00687 Insights on Improved Meat QualityEnhanced Disease ResistanceImproved Growth PerformanceRegulated Cytokine ExpressionEnhanced Resistance to E. coliReduced Inflammatory Blood MarkersReduced Inflammation Levels
Safety evaluation of Lactobacillus delbrueckii subsp. lactis UO 004, a probiotic bacterium.2005-03Research in Microbiology 156(2)M. F. FernándezS. BorisC. BarbésPubMed: 15748979DOI: 10.1016/J.RESMIC.2004.09.0063 Insights on Reduced Antibiotic SensitivityAbsence of Harmful Enzymatic ActivitiesMaintained Normal Intestinal Microbiota
Oral administration of Lactobacillus delbrueckii enhances intestinal immunity through inducing dendritic cell activation in suckling piglets.2022Food & Function 13(5)Wei PengYinghui LiGuan YangJie-Lin DuanLingyuan YangLi-Xiang ChenShuling HouXingguo HuangPubMed: 35166282DOI: 10.1039/d1fo03864h9 Insights on Increased Ileum Interleukin-10 LevelsEnhanced Intestinal ImmunityElevated Ileum IL-4 LevelsIncreased Dendritic Cell ActivationLong-Lasting Immunomodulatory Effects After WeaningImproved Gut Microbial DiversityImproved Gut Microbiota DiversityImproved Dendritic Cell ActivationElevated Serum TNF-α Levels
Lactobacillus delbrueckii CIDCA 133 Ameliorates Chemotherapy-Induced Mucositis by Modulating Epithelial Barrier and TLR2/4/Myd88/NF-κB Signaling Pathway2022-04-26Frontiers in Microbiology 13F. A. L. BarrosoL. D. de JesusT. F. da SilvaV. L. BatistaJ. LagunaN. D. Coelho-RochaK. D. VitalS. O. FernandesV. CardosoÊ. FerreiraF. S. MartinsM. M. DrumondPamela Mancha-AgrestiAlexander BirbrairD. BarhV. AzevedoPubMed: 35558121DOI: 10.3389/fmicb.2022.8580367 Insights on Reduced Intestinal PermeabilityImproved Small Intestine LengthImproved Intestinal Mucosa ArchitectureIncreased Ileal Goblet Cell CountReduced Immune Cell InfiltrationReduced Villus AtrophyReduced Inflammatory Response
Lactobacillus delbrueckii Protected Intestinal Integrity, Alleviated Intestinal Oxidative Damage, and Activated Toll-Like Receptor–Bruton’s Tyrosine Kinase–Nuclear Factor Erythroid 2-Related Factor 2 Pathway in Weaned Piglets Challenged with Lipopolysaccharide2021-03-16Antioxidants 10(3)Fengming ChenJiayi ChenQinghua ChenLingyuan YangJ. YinYinghui LiXingguo HuangPubMed: 33809627DOI: 10.3390/antiox100304684 Insights on Enhanced Immune Response through TLR-Btk-Nrf2 Signaling PathwayImproved Antioxidant FunctionImproved Intestinal Barrier IntegrityReduced Intestinal Oxidative Damage
Lactobacillus delbrueckii Ameliorates Intestinal Integrity and Antioxidant Ability in Weaned Piglets after a Lipopolysaccharide Challenge2020-02-10Oxidative Medicine and Cellular Longevity 2020Fengming ChenHoujun WangJiayi ChenYang LiuWei WenYinghui LiXingguo HuangPubMed: 32104535DOI: 10.1155/2020/60286065 Insights on Reduced Inflammatory Cytokine LevelsImproved Intestinal MorphologyImproved Intestinal Barrier FunctionImproved Antioxidant CapacityReduced Inflammatory Response
Early treatment with Lactobacillus delbrueckii strain induces an increase in intestinal T-cells and granulocytes and modulates immune-related genes of larval Dicentrarchus labrax (L.).2009-03Fish & Shellfish Immunology 26(3)S. PicchiettiA. FaustoE. RandelliO. CarnevaliA. TaddeiF. BuonocoreG. ScapigliatiL. AbelliPubMed: 18996487DOI: 10.1016/j.fsi.2008.10.0085 Insights on Increased Intestinal T-Cell CountImproved Gut Immune FunctionReduced Pro-inflammatory Gene TranscriptionEnhanced Gut Immune FunctionReduced Inflammation Levels
Effects of Dietary Supplementation of Lactobacillus delbrueckii on Gut Microbiome and Intestinal Morphology in Weaned Piglets2021-08-19Frontiers in Veterinary Science 8Xiao-Long WangZhu-Ying LiuYinghui LiLingyuan YangJ. YinJianhua HeD. HouYa-Li LiuXingguo HuangPubMed: 34490392DOI: 10.3389/fvets.2021.6923899 Insights on Improved HDL Cholesterol LevelsIncreased Abundance of FirmicutesIncreased Gut BifidobacteriaDecreased Relative Abundance of Unclassified ClostridialesImproved Growth PerformanceReduced Bacteroidetes AbundanceElevated Insulin LevelsImproved Intestinal Villus HeightIncreased Fecal Lactobacilli
Lactobacillus delbrueckii might lower serum triglyceride levels via colonic microbiota modulation and SCFA-mediated fat metabolism in parenteral tissues of growing-finishing pigs2022-09-29Frontiers in Veterinary Science 9G. HouJ. YinLiangkai WeiRui LiWei PengYong YuanXingguo HuangY. YinPubMed: 36246311DOI: 10.3389/fvets.2022.9823497 Insights on Improved Abundance of Beneficial BacteriaIncreased Butyrate LevelsReduced Serum TriglyceridesIncreased Colonic Butyric Acid ConcentrationsIncreased Serum Free Fatty Acid LevelsReduced Serum Triglyceride LevelsIncreased Free Fatty Acid Levels
Effects of Lactobacillus delbrueckii on immune response, disease resistance against Aeromonas hydrophila, antioxidant capability and growth performance of Cyprinus carpio Huanghe var2017-09Fish & Shellfish Immunology 68Chunnuan ZhangJi-liang ZhangWen-Chao GuanXiao-Fei ZhangSuhong GuanQing-Hui ZengG. ChengWei CuiPubMed: 28698125DOI: 10.1016/j.fsi.2017.07.0125 Insights on Enhanced Antioxidant ActivityImproved Antioxidant FunctionImproved Immune ResponseEnhanced Disease ResistanceImproved Growth Performance
The study on the candidate probiotic properties of encapsulated yeast, Saccharomyces cerevisiae JCM 7255, in Nile Tilapia (Oreochromis niloticus).2015-10Research in Veterinary Science 102K. PinpimaiC. RodkhumN. ChansueT. KatagiriM. MaitaN. PiraratPubMed: 26412528DOI: 10.1016/j.rvsc.2015.07.0214 Insights on Reduced Streptococcus agalactiae GrowthImproved Intestinal Mucosal ImmunityImproved Growth PerformanceReduced Cumulative Mortality