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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Effectiveness of herbal medicines to prevent and control symptoms of urinary tract infections and to reduce antibiotic use: A literature review.
- 2022-12
- Review
- Integrative medicine research 11(4)
- - Herman van Wietmarschen
  - Noortje van Steenbergen
  - Esther van der Werf
  - Erik Baars
- PubMed: 36345487
- DOI: 10.1016/j.imr.2022.100892
1 Insight on
- Reduced Risk of Urinary Tract Infection
- Low evidence
Effects of tart cherry juice consumption on cardio-metabolic risk factors: A systematic review and meta-analysis of randomized-controlled trials.
- 2022-12
- Meta-Analysis
- Complementary therapies in medicine 71
- - Seyedeh Parisa Moosavian
  - Maryam Maharat
  - Mahla Chambari
  - Fateme Moradi
  - Mehran Rahimlou
- PubMed: 36038032
- DOI: 10.1016/j.ctim.2022.102883
10 Insights on
- High evidence
Bifidobacterium animalis subsp. lactis Bi-07 supports lactose digestion in vitro and in randomized, placebo- and lactase-controlled clinical trials
- 2022-12
- RCT
- The American Journal of Clinical Nutrition 116(6)
- - Pia Rasinkangas
  - S. Forssten
  - M. Marttinen
  - A. Ibarra
  - G. Bothe
  - J. Junnila
  - R. Uebelhack
  - Y. Donazzolo
  - A. Ouwehand
- PubMed: 36149331
- DOI: 10.1093/ajcn/nqac264
5 Insights on
- High evidence
Herbal Medicines for Idiopathic Male Infertility: A Systematic Review.
- 2022-11
- Systematic Review · n = 1,218
- Current drug discovery technologies 19(6)
- - Mohammad Ahmadian
  - Roshanak Salari
  - Mohammad Reza Noras
  - Hamid Reza Bahrami-Taghanaki
- PubMed: 35993457
- DOI: 10.2174/1570163819666220820122101
1 Insight on
- Improved Sperm Count
- High evidence
N-Acetyl Cysteine in Rodenticide Poisoning: A Systematic Review and Meta-Analysis.
- 2022-11
- Meta-Analysis · n = 492
- Current reviews in clinical and experimental pharmacology 17(3)
- - Muhammed Rashid
  - Viji Pulikkel Chandran
  - Sreedharan Nair
  - Deepa Sudalai Muthu
  - Jemima Pappuraj
  - Krupa Ann Jacob
  - Balaji Sridhar
  - Karen Mark
  - Shabnam Hyder
  - Sohil Khan
  - Girish Thunga
- PubMed: 34455951
- DOI: 10.2174/2772432816666210825102726
4 Insights on
- High evidence
Efficacy and safety of oral Nigella sativa oil for symptomatic treatment of knee osteoarthritis: A double-blind, randomized, placebo-controlled clinical trial.
- 2022-11
- RCT · n = 58
- Complementary therapies in clinical practice 49
- - Hasan Fallah Huseini
  - Reza Mohtashami
  - Elaheh Sadeghzadeh
  - Soraya Shadmanfar
  - Fataneh Hashem-Dabaghian
  - Saeed Kianbakht
- PubMed: 36150238
- DOI: 10.1016/j.ctcp.2022.101666
10 Insights on
- High evidence
Orally Ingested Probiotics, Prebiotics, and Synbiotics as Countermeasures for Respiratory Tract Infections in Nonelderly Adults: A Systematic Review and Meta-Analysis.
- 2022-11
- Meta-Analysis · n = 9,179
- Advances in nutrition (Bethesda, Md.) 13(6)
- - Julie L Coleman
  - Adrienne Hatch-McChesney
  - Stephanie D Small
  - Jillian T Allen
  - Elaine Sullo
  - Richard T Agans
  - Heather S Fagnant
  - Asma S Bukhari
  - J Philip Karl
- PubMed: 35948276
- DOI: 10.1093/advances/nmac086
1 Insight on
- Reduced Risk of Upper Respiratory Tract Infections
- High evidence
Bach Flower Remedies as Complementary Therapies in Health Care: A Scope Review.
- 2022-11
- Review
- Holistic nursing practice 36(6)
- - Mayara Araújo Rocha
  - Cintia Galvão Queiroz
  - Kauanny Vitoria Gurgel Dos Santos
  - Joyce Karolayne Dos Santos Dantas
  - Sara Cristina Matias de Araujo
  - Samia Valeria Ozorio Dutra
  - Daniele Vieira Dantas
  - Rodrigo Assis Neves Dantas
- PubMed: 36255345
- DOI: 10.1097/hnp.0000000000000552
4 Insights on
- Low evidence
Preoperative fasting for the infusion of "yerba mate": a randomized clinical trial with ultrasound evaluation of gastric contents.
- 2022-11
- RCT
- Brazilian journal of anesthesiology (Elsevier) 72(6)
- - Paola Alcarraz
  - Liliana Servente
  - Federico Kuster
  - Leticia Duarte
  - Mariela Garau
  - María Desirello
  - Lourdes Blanc
  - Nelson Bracesco
  - Anahi Perlas
- PubMed: 35121062
- DOI: 10.1016/j.bjane.2021.12.010
2 Insights on
- Reduced Gastric Emptying Time
- Reduced Gastric Volume
- High evidence
Lactobacillus paracasei IMC 502 ameliorate type 2 diabetes by mediating gut microbiota-SCFAs-hormone/inflammation pathway in mice.
- 2022-11
- Clinical Trial
- Journal of the Science of Food and Agriculture 103(6)
- - Yuxiang Gu
  - Haoran Chen
  - Xing Li
  - Dan Li
  - Yue Sun
  - Lin Yang
  - Ying Ma
  - E. Chan
- PubMed: 36221226
- DOI: 10.1002/jsfa.12267
11 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Plasma l-carnitine and risks of cardiovascular events and recurrent stroke after ischemic stroke: A nested case-control study.
- 2022-11
- RCT · n = 323
- Nutrition, metabolism, and cardiovascular diseases : NMCD 32(11)
- - Jigang Du
  - Mengyuan Miao
  - Zian Lu
  - Haichang Chen
  - Anran Bao
  - Bizhong Che
  - Jintao Zhang
  - Zhong Ju
  - Tan Xu
  - Jiang He
  - Yonghong Zhang
  - Chongke Zhong
- PubMed: 36155150
- DOI: 10.1016/j.numecd.2022.08.016
2 Insights on
- Reduced Cardiovascular Event Risk
- Reduced Stroke Recurrence Risk
- High evidence
- Large Human Trial
Effect of macular pigment carotenoids on cognitive functions: A systematic review.
- 2022-10
- Systematic Review
- Physiology & behavior 254
- - Marta-C García-Romera
  - María-Carmen Silva-Viguera
  - Inmaculada López-Izquierdo
  - Alfredo López-Muñoz
  - Raúl Capote-Puente
  - Beatriz Gargallo-Martínez
- PubMed: 35752349
- DOI: 10.1016/j.physbeh.2022.113891
7 Insights on
- High evidence
Effects of Bacillus coagulans GBI-30, 6086 as an adjunct starter culture on the production of yogurt.
- 2022-10
- Food research international (Ottawa, Ont.) 160
- - Jiang Cao
  - Zhiming Yu
  - Qingsong Zhang
  - Leilei Yu
  - Jianxin Zhao
  - Hao Zhang
  - Wei Chen
  - Qixiao Zhai
- PubMed: 36076366
- DOI: 10.1016/j.foodres.2022.111398
1 Insight on
- Improved Survival of Probiotic Bacteria
- Low evidence
Isolation, characterization and anti-UVB irradiation activity of an extracellular polysaccharide produced by Lacticaseibacillus rhamnosus VHPriobi O17.
- 2022-10
- Heliyon 8(10)
- - Shudong Peng
  - Chaoqun Guo
  - Songjie Wu
  - Zhi Duan
- PubMed: 36299523
- DOI: 10.1016/j.heliyon.2022.e11125
4 Insights on
- Low evidence
Effects of milk protein concentrate supplementation on metabolic parameters, adipocytokines and body composition in obese women under weight-loss diet: study protocol for a randomised controlled trial.
- 2022-10
- RCT
- BMJ open 12(10)
- - Fatemeh Haidari
  - Mahsa Elahikhah
  - Sheikh Mohammed Shariful Islam
  - Majid Mohammadshahi
  - Hajieh Shahbazian
  - Vahideh Aghamohammadi
- PubMed: 36202586
- DOI: 10.1136/bmjopen-2022-064727
8 Insights on
- High evidence
Acetyl-L-carnitine Slows the Progression from Prefrailty to Frailty in Older Subjects: A Randomized Interventional Clinical Trial.
- 2022-10
- RCT · n = 92
- Current pharmaceutical design 28(38)
- - Giulia Malaguarnera
  - Vito Emanuele Catania
  - Gaetano Bertino
  - Laura Maria Chisari
  - Maria Castorina
  - Claudia Bonfiglio
  - Omar Cauli
  - Michele Malaguarnera
- PubMed: 36043711
- DOI: 10.2174/1381612828666220830092815
4 Insights on
- High evidence
Consumption of oils and anthocyanins may positively modulate PPAR-γ expression in chronic noncommunicable diseases: A systematic review.
- 2022-09
- Systematic Review · n = 346
- Nutrition research (New York, N.Y.) 105
- - Isabela de Souza da Costa Brum
  - Denise Mafra
  - Laís de Souza Gouveia Moreira
  - Karla Thaís Resende Teixeira
  - Milena Barcza Stockler-Pinto
  - Ludmila Ferreira Medeiros de França Cardozo
  - Natalia Alvarenga Borges
- PubMed: 35905655
- DOI: 10.1016/j.nutres.2022.06.004
1 Insight on
- Improved Peroxisome Proliferator-Activated Receptor Gamma Expression
- High evidence
Effect of cocoa (Theobroma cacao L.) on platelet function testing profiles in patients with coronary artery disease: ECLAIR pilot study.
- 2022-09
- Clinical Trial · n = 20
- Open heart 9(2)
- - Naveen Anand Seecheran
  - Darin Sukha
  - Kathryn Grimaldos
  - Gabriella Grimaldos
  - Srivane Richard
  - Aleena Ishmael
  - Ceylon Gomes
  - Lirmala Kampradi
  - Rajeev Seecheran
  - Valmiki Seecheran
  - Lakshmipathi Peram
  - Darren Dookeeram
  - Stanley Giddings
  - Sherry Sandy
  - Anil Ramlackhansingh
  - Sadi Raza
  - Pathmanathan Umaharan
  - Antonio Tello-Montoliu
  - David Schneider
- PubMed: 36100318
- DOI: 10.1136/openhrt-2022-002066
2 Insights on
- Increased Platelet Count
- Reduced Platelet Reactivity
- Moderate evidence
Characterization of autochthonous lactobacilli from goat dairy products with probiotic potential for metabolic diseases.
- 2022-09
- Heliyon 8(9)
- - Antonela Marquez
  - Estefanía Andrada
  - Matias Russo
  - María Lujan Bolondi
  - Emanuel Fabersani
  - Roxana Medina
  - Paola Gauffin-Cano
- PubMed: 36091951
- DOI: 10.1016/j.heliyon.2022.e10462
4 Insights on
- Low evidence
The beneficial effect of tart cherry on plasma levels of inflammatory mediators (not recovery after exercise): A systematic review and meta-analysis on randomized clinical trials.
- 2022-09
- Meta-Analysis
- Complementary therapies in medicine 68
- - Ali Gholami
  - Bahareh Amirkalali
  - Hamid Reza Baradaran
  - Mitra Hariri
- PubMed: 35653966
- DOI: 10.1016/j.ctim.2022.102842
3 Insights on
- High evidence
Safety and efficacy of a feed additive consisting of Limosilactobacillus reuteri (formerly Lactobacillus reuteri) DSM 32264 as a feed additive for cats (NBF Lanes s.r.l.)
- 2022-08
- EFSA Journal 20(8)
- - V. Bampidis
  - G. Azimonti
  - M. Bastos
  - Henrik Christensen
  - Birgit Dusemund
  - Mojca Fašmon Durjava
  - M. Kouba
  - M. López-Alonso
  - Secundino López Puente
  - F. Marcon
  - B. Mayo
  - A. Pechová
  - M. Petkova
  - F. Ramos
  - Yolanda Sanz
  - R. Villa
  - R. Woutersen
  - G. Martelli
  - M. Anguita
  - J. Galobart
  - J. Ortuño
  - J. Revez
  - Rosella Brozzi
- PubMed: 35949936
- DOI: 10.2903/j.efsa.2022.7437
2 Insights on
- Improved Stool Consistency
- Increased Constipation Risk
- Low evidence
The role of selected nutraceuticals in management of prediabetes and diabetes: An updated review of the literature.
- 2022-08
- Review
- Phytotherapy research : PTR 36(10)
- - Giuseppe Derosa
  - Angela D'Angelo
  - Pamela Maffioli
- PubMed: 35912631
- DOI: 10.1002/ptr.7564
4 Insights on
- Low evidence
Effect of the addition of the probiotic Bifidobacterium animalis subsp. Lactis (BB-12) in free and microencapsulated form and the prebiotic inulin to synbiotic dry coppa.
- 2022-08
- Food research international (Ottawa, Ont.) 158
- - Talita Aparecida Ferreira de Campos
  - Annecler Rech de Marins
  - Natallya Marques da Silva
  - Marcos Antonio Matiucci
  - Iza Catarini Dos Santos
  - Claudete Regina Alcalde
  - Maria Luiza Rodrigues de Souza
  - Raquel Guttierres Gomes
  - Andresa Carla Feihrmann
- PubMed: 35840239
- DOI: 10.1016/j.foodres.2022.111544
3 Insights on
- Low evidence
Therapeutic effect of heat-killed Lactobacillus plantarum L-137 on the gut health and growth of broilers.
- 2022-08
- RCT
- Acta tropica 232
- - Hai Ha Pham Thi
  - Tuong Vi Phan Thi
  - Ninh Pham Huynh
  - Vinh Doan
  - Satoru Onoda
  - Thanh Luan Nguyen
- PubMed: 35623400
- DOI: 10.1016/j.actatropica.2022.106537
3 Insights on
- Low evidence
- Animal Study
Assessment of the efficacy of a feed additive consisting of Limosilactobacillus reuteri (formerly Lactobacillus reuteri) DSM 32203 for dogs (NBF LANES)
- 2022-07
- EFSA Journal 20(7)
- - V. Bampidis
  - G. Azimonti
  - M. Bastos
  - Henrik Christensen
  - B. Dusemund
  - Mojca Fašmon Durjava
  - M. Kouba
  - M. López-Alonso
  - Secundino López Puente
  - F. Marcon
  - B. Mayo
  - A. Pechová
  - M. Petkova
  - F. Ramos
  - Yolanda Sanz
  - R. Villa
  - R. Woutersen
  - G. Martelli
  - M. Anguita
  - Rosella Brozzi
  - J. Galobart
  - J. Ortuño
  - J. Revez
- PubMed: 35865118
- DOI: 10.2903/j.efsa.2022.7436
2 Insights on
- Improved Stool Consistency
- Increased Constipation Risk
- Low evidence
Morus Alba leaf extract affects metabolic profiles, biomarkers inflammation and oxidative stress in patients with type 2 diabetes mellitus: A double-blind clinical trial.
- 2022-06
- RCT · n = 60
- Clinical nutrition ESPEN 49
- - Mohsen Taghizadeh
  - Azam Mohammad Zadeh
  - Zatollah Asemi
  - Amir Hosein Farrokhnezhad
  - Mohammad Reza Memarzadeh
  - Zarin Banikazemi
  - Mohammad Shariat
  - Rana Shafabakhsh
- PubMed: 35623877
- DOI: 10.1016/j.clnesp.2022.03.027
10 Insights on
- High evidence
The effect of the probiotic consortia on SARS-CoV-2 infection in ferrets and on human immune cell response in vitro.
- 2022-06
- iScience 25(6)
- - Markus J Lehtinen
  - Ritesh Kumar
  - Bryan Zabel
  - Sanna M Mäkelä
  - Derek Nedveck
  - Peipei Tang
  - Sinikka Latvala
  - Sebastien Guery
  - Charles R Budinoff
- PubMed: 35634575
- DOI: 10.1016/j.isci.2022.104445
2 Insights on
- Reduced Viral Load
- Modulated Immune Response
- Low evidence
N-acetyl cysteine in the treatment of cannabis use disorder: A systematic review of clinical trials.
- 2022-06
- Systematic Review
- Addictive behaviors 129
- - Rishi Sharma
  - Sai Krishna Tikka
  - Ashish Ramesh Bhute
  - Binaya Kumar Bastia
- PubMed: 35189496
- DOI: 10.1016/j.addbeh.2022.107283
3 Insights on
- High evidence
Effects of diet on the outcomes of rheumatic and musculoskeletal diseases (RMDs): systematic review and meta-analyses informing the 2021 EULAR recommendations for lifestyle improvements in people with RMDs.
- 2022-06
- Meta-Analysis · n = 83
- RMD open 8(2)
- - James M Gwinnutt
  - Maud Wieczorek
  - Javier Rodríguez-Carrio
  - Andra Balanescu
  - Heike A Bischoff-Ferrari
  - Annelies Boonen
  - Giulio Cavalli
  - Savia de Souza
  - Annette de Thurah
  - Thomas E Dorner
  - Rikke Helene Moe
  - Polina Putrik
  - Lucía Silva-Fernández
  - Tanja Stamm
  - Karen Walker-Bone
  - Joep Welling
  - Mirjana Zlatković-Švenda
  - Francis Guillemin
  - Suzanne M M Verstappen
- PubMed: 35654458
- DOI: 10.1136/rmdopen-2021-002167
2 Insights on
- Reduced Pain
- Improved Function
- High evidence
Effects of Pueraria mirifica on vaginal artery vascularization in postmenopausal women with genitourinary syndrome of menopause.
- 2022-06
- RCT
- Maturitas 160
- - Patsira Warinsiriruk
  - Chananya Tantitham
  - Wichai Cherdshewasart
  - S Abbas Shobeiri
  - Jittima Manonai
- PubMed: 35550707
- DOI: 10.1016/j.maturitas.2022.01.005
4 Insights on
- High evidence