February 2022 Supplement Research Papers

• February 3

  • Role of Lactobacillus plantarum 299v versus Placebo in symptomatic improvement of irritable bowel syndrome patients.

    • 2022-02-03
    • RCT · n = 190
    • JPMA. The Journal of the Pakistan Medical Association 72(3)
    • • Ahmad Nawaz Babar
      • Muhammad Kamran Hassan
      • Fazl Ullah
      • Anwar Ullah

    • PubMed: 35320214
    • DOI: 10.47391/jpma.0758

    7 Insights on

    • Improved Bowel Movement Frequency
    • Reduced Bloating
    • Reduced Flatulence
    • Reduced Abdominal Pain
    • Improved Irritable Bowel Syndrome Symptoms
    • Reduced Irritable Bowel Syndrome Symptoms
    • Improved Rectal Emptying

    • High evidence
    • Large Human Trial
• February 4

  • Effects of Exopolysaccharides from Lactiplantibacillus plantarum JLAU103 on Intestinal Immune Response, Oxidative Stress, and Microbial Communities in Cyclophosphamide-Induced Immunosuppressed Mice.

    • 2022-02-04
    • Clinical Trial
    • Journal of Agricultural and Food Chemistry 70(7)
    • • Ji Wang
      • Meihe Li
      • Yawen Gao
      • Hongmei Li
      • Li Fang
      • Chunlei Liu
      • Xiaoting Liu
      • Weihong Min

    • PubMed: 35118857
    • DOI: 10.1021/acs.jafc.1c06502

    7 Insights on

    • Improved Intestinal Barrier Function
    • Increased Short-Chain Fatty Acid Production
    • Enhanced Intestinal Immunity
    • Modulated Gut Microbiota
    • Increased Cytokine Secretion
    • Protection Against Oxidative Stress
    • Improved Systemic Immunity

    • Low evidence
    • Animal Study

  • Heat-Killed Lacticaseibacillus paracasei GMNL-653 Exerts Antiosteoporotic Effects by Restoring the Gut Microbiota Dysbiosis in Ovariectomized Mice

    • 2022-02-04
    • Clinical Trial
    • Frontiers in Nutrition 9
    • • Jhih-Hua Jhong
      • W. Tsai
      • Li-Chan Yang
      • Chia-Hsuan Chou
      • Tzong-Yi Lee
      • Y. Yeh
      • Cheng-Hsieh Huang
      • Yueh-Hsia Luo

    • PubMed: 35187034
    • DOI: 10.3389/fnut.2022.804210

    4 Insights on

    • Improved Intestinal Barrier Integrity
    • Reduced Inflammation Levels
    • Improved Gut Microbiota Balance
    • Improved Bone Health

    • Low evidence
    • Animal Study
• February 6

  • A Systematic Review and Meta-Analysis: Lactobacillus acidophilus for Treating Acute Gastroenteritis in Children

    • 2022-02-06
    • Meta-Analysis
    • Nutrients 14(3)
    • • Haixin Cheng
      • Yi Ma
      • Xiaohui Liu
      • Chao Tian
      • Xuli Zhong
      • Libo Zhao

    • PubMed: 35277042
    • DOI: 10.3390/nu14030682

    4 Insights on

    • Reduced Duration of Diarrhea
    • Reduced Diarrhea Rate
    • Reduced Diarrhea Frequency
    • No Change in Diarrhea Duration

    • High evidence
• February 7

  • Lactobacillus rhamnosus CNCM I-3690 decreases subjective academic stress in healthy adults: a randomized placebo-controlled trial

    • 2022-02-07
    • RCT · n = 46
    • Gut Microbes 14(1)
    • • L. Wauters
      • L. Van Oudenhove
      • A. Accarie
      • K. Geboers
      • H. Geysen
      • Joran Tóth
      • A. Luypaerts
      • K. Verbeke
      • T. Smokvina
      • J. Raes
      • J. Tack
      • T. Vanuytsel

    • PubMed: 35130109
    • DOI: 10.1080/19490976.2022.2031695

    13 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Subjective Academic Stress
    • Reduced Stress-Induced Hyperpermeability
    • Reduced Subjective Stress Levels
    • Absence of Adverse Effects
    • Reduced Perceived Stress
    • No Change in Abnormal Intestinal Permeability
    • Reduced Stress Markers
    • No Change in Objective Stress Markers
    • Reduced Stress-Induced Intestinal Permeability to Mannitol
    • Reduced Stress-Induced Anxiety
    • Reduced Stress-Induced Intestinal Hyperpermeability
    • Maintained Small Intestinal Permeability

    • High evidence
    • Rigorous Journal

  • Bacillus coagulans TL3 Inhibits LPS-Induced Caecum Damage in Rat by Regulating the TLR4/MyD88/NF-κB and Nrf2 Signal Pathways and Modulating Intestinal Microflora

    • 2022-02-07
    • RCT · n = 14
    • Oxidative Medicine and Cellular Longevity 2022
    • • Yan Wang
      • Jianxin Lin
      • Ziyang Cheng
      • Tiancheng Wang
      • Jia Chen
      • M. Long

    • PubMed: 35178157
    • DOI: 10.1155/2022/5463290

    18 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Hepatic Oxidative Stress
    • Reduced Inflammatory Response
    • Improved Intestinal Barrier Integrity
    • Reduced Intestinal Inflammation
    • Reduced Inflammation Levels
    • Reduced Intestinal Oxidative Damage
    • Improved Abundance of Beneficial Bacteria
    • Reduced Harmful Gut Bacteria
    • Enhanced Intestinal Immunity
    • Improved Gut Microbiome Composition
    • Improved Gut Microflora
    • Reduced Oxidative Damage
    • Reduced Harmful Gut Microbiota
    • Improved Beneficial Intestinal Bacteria
    • Reduced Total Bacterial Levels
    • Reduced Harmful Intestinal Bacteria
    • Enhanced Gut Flora Composition

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Agave fructans: a review of their technological functionality and extraction processes.

    • 2022-02-07
    • Review
    • Journal of food science and technology 60(4)
    • • Wendy Guadalupe García-Villalba
      • Raúl Rodríguez-Herrera
      • Luz Araceli Ochoa-Martínez
      • Olga Miriam Rutiaga-Quiñones
      • José Alberto Gallegos-Infante
      • Silvia Marina González-Herrera

    • PubMed: 36936110
    • DOI: 10.1007/s13197-022-05375-7

    1 Insight on

    • No Human Health Outcome Reported

    • Low evidence
• February 9

  • Lactobacillus rhamnosus L34 attenuates chronic kidney disease progression in 5/6 nephrectomy mouse model through the excretion of anti-inflammatory molecules.

    • 2022-02-09
    • Nephrology Dialysis Transplantation 37(8)
    • • S. Tungsanga
      • P. Katavetin
      • Wimonrat Panpetch
      • Kanyarat Udompornpitak
      • Wilasinee Saisorn
      • K. Praditpornsilpa
      • S. Eiam‐Ong
      • K. Tungsanga
      • S. Tumwasorn
      • A. Leelahavanichkul

    • PubMed: 35138387
    • DOI: 10.1093/ndt/gfac032

    7 Insights on

    • Reduced Inflammation Levels
    • Reduced Serum Creatinine Levels
    • Improved Gut Integrity
    • Reduced TNF-α Levels
    • Reduced Proteinuria Levels
    • Reduced Kidney Fibrosis
    • Reduced Levels of Gut-Derived Uremic Toxins

    • Low evidence
• February 10

  • Nondairy Probiotic Products: Functional Foods That Require More Attention.

    • 2022-02-10
    • Review
    • Nutrients 14(4)
    • • Kübra Küçükgöz
      • Monika Trząskowska

    • PubMed: 35215403
    • DOI: 10.3390/nu14040753

    1 Insight on

    • No Human Health Outcome Reported

    • Moderate evidence
    • Rigorous Journal
• February 11

  • Overexpression of MET4 Leads to the Upregulation of Stress-Related Genes and Enhanced Sulfite Tolerance in Saccharomyces uvarum.

    • 2022-02-11
    • Cells 11(4)
    • • Zhuo Wei
      • Zhiming Zhang
      • Wenjuan Zhao
      • Tuo Yin
      • Xiaozhen Liu
      • Hanyao Zhang

    • PubMed: 35203287
    • DOI: 10.3390/cells11040636

    1 Insight on

    • Increased Sulfite Tolerance

    • Low evidence

  • L-DOPA administration shifts the stability-flexibility balance towards attentional capture by distractors during a visual search task.

    • 2022-02-11
    • RCT
    • Psychopharmacology 239(3)
    • • P Riedel
      • I M Domachowska
      • Y Lee
      • P T Neukam
      • L Tönges
      • S C Li
      • T Goschke
      • M N Smolka

    • PubMed: 35147724
    • DOI: 10.1007/s00213-022-06077-w

    1 Insight on

    • Increased Distractibility

    • High evidence

  • Regulation divergences of Lactobacillus fermentum PCC and Lactobacillus paracasei 431 on penicillin-induced upper respiratory tract microbial dysbiosis in BALB/c mice.

    • 2022-02-11
    • Clinical Trial
    • Food & Function 12(23)
    • • F. Gao
      • Zhifeng Fang
      • Wenwei Lu

    • PubMed: 34739535
    • DOI: 10.1039/d0fo02981e

    2 Insights on

    • Restored Microbial Community Structure in Upper Respiratory Tract
    • Regulated Systemic Immune Response Imbalance

    • Low evidence
    • Animal Study
• February 12

  • Antioxidant Status, Blood Constituents and Immune Response of Broiler Chickens Fed Two Types of Diets with or without Different Concentrations of Active Yeast.

    • 2022-02-12
    • Clinical Trial · n = 216
    • Animals : an open access journal from MDPI 12(4)
    • • Youssef A Attia
      • Hanan Al-Khalaifah
      • Hatem S Abd El-Hamid
      • Mohammed A Al-Harthi
      • Salem R Alyileili
      • Ali A El-Shafey

    • PubMed: 35203163
    • DOI: 10.3390/ani12040453

    4 Insights on

    • Improved Immune Function
    • Improved Total Antioxidant Status
    • Improved Hematological Parameters
    • Improved Immune Response to Vaccination

    • High evidence

  • Nine-Strain Bacterial Synbiotic Improves Crying and Lowers Fecal Calprotectin in Colicky Babies-An Open-Label Randomized Study.

    • 2022-02-12
    • RCT · n = 50
    • Microorganisms 10(2)
    • • Malgorzata Bernatek
      • Jacek Piątek
      • Marcin Pszczola
      • Hanna Krauss
      • Janina Antczak
      • Paweł Maciukajć
      • Henning Sommermeyer

    • PubMed: 35208884
    • DOI: 10.3390/microorganisms10020430

    2 Insights on

    • Reduced Crying Duration
    • Reduced Faecal Calprotectin

    • High evidence
• February 14

  • Lactobacillus casei LC89 exerts antidiabetic effects through regulating hepatic glucagon response and gut microbiota in type 2 diabetic mice.

    • 2022-02-14
    • Clinical Trial
    • Food & Function 12(18)
    • • Yongli Zhang
      • Tao Wu
      • W. Li
      • Yunjiao Zhao
      • Hairong Long
      • R. Liu
      • Wenjie Sui
      • M. Zhang

    • PubMed: 34308462
    • DOI: 10.1039/d1fo00882j

    8 Insights on

    • Improved Insulin Sensitivity
    • Reduced Inflammation Levels
    • Reduced Pro-inflammatory Cytokine Levels
    • Improved Serum Lipids
    • Reduced Fasting Blood Sugar Levels
    • Reduced Insulin Levels
    • Reduced Fasting Blood Glucose Levels
    • Reduced Glucagon Pathway Activity

    • Low evidence
    • Animal Study

  • "Precovery" versus recovery: Understanding the role of cherry juice in exercise recovery.

    • 2022-02-14
    • Review
    • Scandinavian journal of medicine & science in sports 32(6)
    • • Malachy P McHugh

    • PubMed: 35119142
    • DOI: 10.1111/sms.14141

    3 Insights on

    • Reduced Inflammation
    • Reduced Muscle Soreness
    • Improved Muscle Function Recovery

    • Low evidence
• February 15

  • Biotechnological Enhancement of Probiotics through Co-Cultivation with Algae: Future or a Trend?

    • 2022-02-15
    • Review
    • Marine drugs 20(2)
    • • Lucija Perković
      • Elvis Djedović
      • Tamara Vujović
      • Marija Baković
      • Tina Paradžik
      • Rozelindra Čož-Rakovac

    • PubMed: 35200671
    • DOI: 10.3390/md20020142

    1 Insight on

    • Improved Gut Health

    • Low evidence

  • Acute Supplementation with Beta-Alanine Improves Performance in Aerobic-Anaerobic Transition Zones in Endurance Athletes.

    • 2022-02-15
    • RCT
    • Journal of the American Nutrition Association 42(2)
    • • Álvaro Huerta Ojeda
      • Guillermo Barahona-Fuentes
      • Sergio Galdames Maliqueo
      • Marcela Guzmán Solis
      • María Mercedes Yeomans Cabrera
      • Carlos Jorquera-Aguilera

    • PubMed: 35512767
    • DOI: 10.1080/07315724.2021.2020183

    1 Insight on

    • Increased Exercise Capacity

    • High evidence
• February 16

  • Bifidobacterium lactis BL-99 modulates intestinal inflammation and functions in zebrafish models.

    • 2022-02-16
    • PloS one 17(2)
    • • Meng Chen
      • Chinfeng Liu
      • Mingzhu Dai
      • Qinwen Wang
      • Chunqi Li
      • Weilian Hung

    • PubMed: 35171916
    • DOI: 10.1371/journal.pone.0262942

    3 Insights on

    • Improved Intestinal Function
    • Reduced Intestinal Inflammation
    • Improved Intestinal Histology

    • Low evidence
    • Animal Study

  • Probiotics and Functional Gastrointestinal Disorders in Pediatric Age: A Narrative Review.

    • 2022-02-16
    • Review
    • Frontiers in pediatrics 10
    • • Manuela Capozza
      • Nicola Laforgia
      • Valentina Rizzo
      • Silvia Salvatore
      • Stefano Guandalini
      • Mariella Baldassarre

    • PubMed: 35252059
    • DOI: 10.3389/fped.2022.805466

    2 Insights on

    • Reduced Hard Stool Incidence
    • Improved Gastroesophageal Reflux Symptoms

    • Low evidence

  • Probiotic Bacillus subtilis LF11 Protects Intestinal Epithelium Against Salmonella Infection

    • 2022-02-16
    • Frontiers in Cellular and Infection Microbiology 12
    • • Rong-Rong Zhang
      • Zhengguang Li
      • X. Gu
      • Jiancun Zhao
      • T. Guo
      • J. Kong

    • PubMed: 35252040
    • DOI: 10.3389/fcimb.2022.837886

    2 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Proinflammatory Cytokines Gene Transcription

    • Low evidence

  • Intestinal Colonization With Bifidobacterium longum Subspecies Is Associated With Length at Birth, Exclusive Breastfeeding, and Decreased Risk of Enteric Virus Infections, but Not With Histo-Blood Group Antigens, Oral Vaccine Response or Later Growth in Three Birth Cohorts

    • 2022-02-16
    • Observational
    • Frontiers in Pediatrics 10
    • • Josh M. Colston
      • M. Taniuchi
      • Tahmina Ahmed
      • Tania Ferdousi
      • F. Kabir
      • E. Mduma
      • R. Nshama
      • N. Iqbal
      • R. Haque
      • T. Ahmed
      • Zulfiqar Ali Bhutta
      • M. Kosek
      • J. Platts-Mills

    • PubMed: 35252058
    • DOI: 10.3389/fped.2022.804798

    6 Insights on

    • Reduced Enteric Virus Infection Rates
    • Increased Birth Length
    • Reduced Viral Infection Incidence
    • No Change in Vaccine Responses
    • No Change in Nutritional Status
    • Reduced Intestinal Colonization

    • Low evidence
• February 17

  • Probiotic Potentiality from Versatile Lactiplantibacillus plantarum Strains as Resource to Enhance Freshwater Fish Health

    • 2022-02-17
    • Microorganisms 10(2)
    • • M. Iorizzo
      • Gianluca Albanese
      • Francesco Letizia
      • Bruno Testa
      • P. Tremonte
      • F. Vergalito
      • S. J. Lombardi
      • M. Succi
      • R. Coppola
      • E. Sorrentino

    • PubMed: 35208917
    • DOI: 10.3390/microorganisms10020463

    4 Insights on

    • Enhanced Disease Resistance
    • Improved Gut Health
    • Improved Antioxidant Activity
    • Reduced Pathogen Activity

    • Low evidence
    • Rigorous Journal
• February 18

  • Effect of Clostridium butyricum on Gastrointestinal Infections

    • 2022-02-18
    • Biomedicines 10(2)
    • • Tadashi Ariyoshi
      • M. Hagihara
      • Motomichi Takahashi
      • H. Mikamo

    • PubMed: 35203691
    • DOI: 10.3390/biomedicines10020483

    7 Insights on

    • Reduced Risk of Antimicrobial Resistance
    • Reduced Pathogenic Bacteria
    • Reduced Nosocomial Infection Rate
    • Maintained Gut Microbiome Homeostasis
    • Reduced Gastric Cancer Pathogen Effectiveness
    • Increased Effectiveness Against Antibiotic-Resistant Bacteria
    • Reduced Transmission of Antibiotic-Resistant Genes

    • Low evidence
    • Rigorous Journal
• February 20

  • Lactobacilli Strain Mixture Alleviates Bacterial Vaginosis through Antibacterial and Antagonistic Activity in Gardnerella vaginalis-Infected C57BL/6 Mice.

    • 2022-02-20
    • Microorganisms 10(2)
    • • Soo-Im Choi
      • GaYeong Won
      • YongGyeong Kim
      • Chang-Ho Kang
      • Gun-Hee Kim

    • PubMed: 35208925
    • DOI: 10.3390/microorganisms10020471

    3 Insights on

    • Improved Epithelial Integrity
    • Reduced Vaginal Pathogen Load
    • Reduced Vaginal Inflammation

    • Low evidence
• February 21

  • Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome

    • 2022-02-21
    • RCT · n = 278
    • World Journal of Gastroenterology 28(7)
    • • J. Sabate
      • F. Iglicki

    • PubMed: 35317278
    • DOI: 10.3748/wjg.v28.i7.732

    3 Insights on

    • Improved Quality of Life
    • Reduced IBS Severity
    • Improved Satisfaction

    • High evidence
    • Rigorous Journal
• February 25

  • Bifidobacterium lactis BL-99 protects mice with osteoporosis caused by colitis via gut inflammation and gut microbiota regulation.

    • 2022-02-25
    • Clinical Trial
    • Food & Function 13(3)
    • • H. Lan
      • Wei-Hsien Liu
      • Hanying Zheng
      • H. Feng
      • Wen Zhao
      • W. Hung
      • Hongwei Li

    • PubMed: 35060590
    • DOI: 10.1039/d1fo02218k

    6 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Colitis Severity
    • Reduced Proinflammatory Cytokine Production
    • Increased Bone Volume
    • Reduced Colitis-Associated Weight Loss
    • Reduced Disease Activity Index Scores

    • Low evidence
    • Animal Study

  • The Combined Use of Pediococcus pentosaceus and Fructooligosaccharide Improves Growth Performance, Immune Response, and Resistance of Whiteleg Shrimp Litopenaeus vannamei Against Vibrio parahaemolyticus

    • 2022-02-25
    • RCT
    • Frontiers in Microbiology 13
    • • N. T. Hồng
      • N. Linh
      • K. Baruah
      • D. Thuy
      • N. N. Phước

    • PubMed: 35283820
    • DOI: 10.3389/fmicb.2022.826151

    3 Insights on

    • Improved Immune Response
    • Improved Growth Performance
    • Enhanced Disease Resistance

    • Low evidence
    • Animal Study
• February 27

  • Lactobacillus helveticus Prevents Periodontitis Induced by Aggregatibacter actinomycetemcomitans in Rats by Regulating β-Defensins

    • 2022-02-27
    • RCT · n = 18
    • Computational and Mathematical Methods in Medicine 2022
    • • Ru Jia
      • Ronghua Shi
      • Danping Guan
      • Yubo Wu
      • Wenhao Qian

    • PubMed: 35265172
    • DOI: 10.1155/2022/4968016

    7 Insights on

    • Reduced Immune Cell Infiltration
    • Reduced Alveolar Bone Resorption
    • Reduced Periodontal Inflammation
    • Reduced Gingival Inflammation
    • Increased Expressions of β-Defensins
    • Improved Alveolar Bone Resorption
    • Reduced Aggregatibacter Actinomycetemcomitans Levels

    • Low evidence
    • Animal Study
• February 28

  • Limosilactobacillus reuteri in Health and Disease

    • 2022-02-28
    • Microorganisms 10(3)
    • • Jumana Abuqwider
      • Mohammad Altamimi
      • G. Mauriello

    • PubMed: 35336098
    • DOI: 10.3390/microorganisms10030522

    4 Insights on

    • Improved Insulin Sensitivity
    • Improved Immunomodulation
    • Improved Gut Integrity
    • Attenuated Hepatic Disorders

    • Low evidence
    • Rigorous Journal

  • Pediococcus acidilactici CECT9879 (pA1c) Counteracts the Effect of a High-Glucose Exposure in C. elegans by Affecting the Insulin Signaling Pathway (IIS)

    • 2022-02-28
    • Clinical Trial
    • International Journal of Molecular Sciences 23(5)
    • • Deyan Yavorov-Dayliev
      • F. Milagro
      • J. Ayo
      • M. Oneca
      • P. Aranaz

    • PubMed: 35269839
    • DOI: 10.3390/ijms23052689

    7 Insights on

    • Improved Insulin Sensitivity
    • Increased Survival Time
    • Reduced Hepatic Fat Accumulation
    • Increased Fatty Acid Oxidation
    • Delayed Skin Aging
    • Improved Fatty Acid Oxidation
    • Reduced Fatty Acid Synthesis

    • Low evidence
    • Animal Study

  • Protective Effects of a Novel Lactobacillus brevis Strain with Probiotic Characteristics against Staphylococcus aureus Lipoteichoic Acid-Induced Intestinal Inflammatory Response

    • 2022-02-28
    • Journal of Microbiology and Biotechnology 32(2)
    • • Won-Ju Kim
      • J. Hyun
      • N. Lee
      • H. Paik

    • PubMed: 34750285
    • DOI: 10.4014/jmb.2110.10034

    2 Insights on

    • Reduced Intestinal Inflammation
    • Reduced IL-8 Production

    • Low evidence

  • Soymilk-fermented with Lactobacillus delbrueckii subsp. delbrueckii TUA4408L improves immune-health in pigs.

    • 2022-02-28
    • Clinical Trial
    • Beneficial Microbes 13(1)
    • • Y. Suda
      • K. Kagawa
      • K. Fukuyama
      • M. Elean
      • B. Zhou
      • M. Tomokiyo
      • M. A. Islam
      • M. Rajoka
      • A. Kober
      • T. Shimazu
      • S. Egusa
      • Y. Terashima
      • H. Aso
      • W. Ikeda-Ohtsubo
      • J. Villena
      • H. Kitazawa

    • PubMed: 35098908
    • DOI: 10.3920/BM2021.0068

    5 Insights on

    • Reduced Inflammatory Markers
    • Improved Growth Performance
    • Reduced Inflammation Levels
    • Enhanced Disease Resistance
    • Enhanced Resistance to E. coli

    • Low evidence
    • Animal Study

  • Evaluation of a Zingiber officinale and Bixa orellana Supplement on the Gut Microbiota of Male Athletes: A Randomized Placebo-Controlled Trial.

    • 2022-02-28
    • RCT
    • Planta medica 88(13)
    • • Diego Domínguez-Balmaseda
      • Carlo Bressa
      • Arantxa Fernández-Romero
      • Beatriz de Lucas
      • Margarita Pérez-Ruiz
      • Alejandro F San Juan
      • Marc Roller
      • Nicolas Issaly
      • Mar Larrosa

    • PubMed: 35226949
    • DOI: 10.1055/a-1671-5766

    3 Insights on

    • Reduced Interleukin-6 Levels
    • Increased Short-Chain Fatty Acid Production
    • Reduced Lipopolysaccharide Level

    • High evidence

  • Lacticaseibacillus rhamnosus GG DSM 33156 effects on pathogen defence in the upper respiratory tract: a randomised, double-blind, placebo-controlled paediatric trial.

    • 2022-02-28
    • RCT · n = 619
    • Beneficial Microbes 13(1)
    • • A. Damholt
      • M. Keller
      • K. Baranowski
      • B. Brown
      • A. Wichmann
      • C. Melsaether
      • D. Eskesen
      • V. Westphal
      • D. Arltoft
      • A. Habicht
      • Q. Gao
      • G. Crawford

    • PubMed: 34895109
    • DOI: 10.3920/BM2021.0065

    4 Insights on

    • No Significant Reduction in URTI Incidence
    • Reduced URTI Symptoms
    • Reduced Incidence Rate of URTIs
    • Reduced Upper Respiratory Tract Infection Symptoms

    • High evidence
    • Large Human Trial

  • Lactobacillus crispatus DSM25988 as novel bioactive agent to co-aggregate Streptococcus pyogenes and to exclude it by binding to human cells.

    • 2022-02-28
    • Beneficial Microbes 13(1)
    • • A. Reiprich
      • L. Skalden
      • A. Raab
      • N. Bolotina
      • C. Lang

    • PubMed: 35144524
    • DOI: 10.3920/BM2021.0103

    6 Insights on

    • Reduced Sore Throat Severity
    • Reduced Adhesion of Streptococcus pyogenes to Human Cells
    • Reduced Invasion of Human Epithelial Pharyngeal Cells by Streptococcus pyogenes
    • Reduced Viral Load in Epithelial Cells
    • Inhibited Streptococcus Pyogenes Invasion
    • Reduced Viral Infection

    • Low evidence
• Undated – 2 supplement studies

  • Probiotic interventions to reduce antepartum Group B streptococcus colonization: A systematic review and meta-analysis.

    • 2022-02
    • Meta-Analysis · n = 709
    • Midwifery 105
    • • Lisa Hanson
      • Leona VandeVusse
      • Emily Malloy
      • Mauricio Garnier-Villarreal
      • Lauren Watson
      • Alissa Fial
      • Marie Forgie
      • Katrina Nardini
      • Nasia Safdar

    • PubMed: 34890880
    • DOI: 10.1016/j.midw.2021.103208

    2 Insights on

    • Reduced Group B Streptococcus Colonization
    • Reduced Group B Streptococcus Activity

    • High evidence

  • Effect of cherry consumption on blood pressure: a systematic review and meta-analysis of randomized controlled trials.

    • 2022-02
    • Meta-Analysis · n = 201
    • Diabetes & metabolic syndrome 16(2)
    • • Omid Eslami
      • Fatemeh Khorramrouz
      • Abed Ghavami
      • Saeedeh Hajebi Khaniki
      • Farzad Shidfar

    • PubMed: 35108661
    • DOI: 10.1016/j.dsx.2022.102409

    2 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Systolic Blood Pressure

    • High evidence