October 2023 Supplement Research Papers

• October 1

  • Quercetin in Sports and Exercise: A review.

    • 2023-10-01
    • Review · n = 34
    • International journal of exercise science 16(2)
    • • Jennifer A Kurtz
      • Trisha A Vandusseldorp
      • Brent Uken
      • Jeff Otis

    • PubMed: 38288402
    • DOI: 10.70252/gqok2958

    12 Insights on

    • Reduced Inflammatory Markers
    • Reduced Lipid Peroxidation
    • Reduced C-Reactive Protein Levels
    • Reduced Muscle Damage
    • Reduced Lactate Dehydrogenase Level
    • Reduced Creatine Kinase Level
    • Improved Time to Exhaustion
    • Improved VO2max
    • Reduced Fatigue Decrement
    • Improved Neuromuscular Function
    • Improved Redox Potential
    • Improved Repeated Sprint Performance

    • Moderate evidence

  • Effects of acute beta-alanine supplementation on post-exertion rating of per-ceived exertion, heart rate, blood lactate, and physical performance on the 6-minute race test in middle-distance runners.

    • 2023-10-01
    • RCT
    • Nutricion hospitalaria 40(5)
    • • Guillermo Barahona-Fuentes
      • Álvaro Huerta Ojeda
      • Sergio Galdames Maliqueo
      • María-Mercedes Yeomans-Cabrera
      • Carlos Jorquera Aguilera

    • PubMed: 37073742
    • DOI: 10.20960/nh.04432

    4 Insights on

    • Improved Physical Performance
    • Increased Blood Lactate Levels
    • Reduced Heart Rate
    • Reduced Perceived Exertion

    • High evidence
• October 2

  • A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab.

    • 2023-10-02
    • RCT
    • Diabetologia 67(1)
    • • Chantal Mathieu
      • Alice Wiedeman
      • Karen Cerosaletti
      • S Alice Long
      • Elisavet Serti
      • Laura Cooney
      • Joan Vermeiren
      • Silvia Caluwaerts
      • Karolien Van Huynegem
      • Lothar Steidler
      • Sven Blomme
      • Pieter Rottiers
      • Gerald T Nepom
      • Kevan C Herold

    • PubMed: 37782353
    • DOI: 10.1007/s00125-023-06014-2

    2 Insights on

    • Improved Metabolic Control in Type 1 Diabetes
    • Reduced Preproinsulin-Specific CD8+ T-Cell Frequency

    • High evidence
• October 3

  • Lactobacillus (Limosilactobacillus) reuteri: a probiotic candidate to reduce neonatal diarrhea in calves

    • 2023-10-03
    • RCT
    • Frontiers in Microbiology 14
    • • K. Schwaiger
      • J. Storch
      • Christoph Bauer
      • Johann Bauer

    • PubMed: 37854332
    • DOI: 10.3389/fmicb.2023.1266905

    1 Insight on

    • Reduced Diarrhea Incidence

    • High evidence
• October 5

  • Review and Perspectives on Bifidobacterium lactis for Infants' and Children's Health.

    • 2023-10-05
    • Review
    • Microorganisms 11(10)
    • • Annie Tremblay
      • Stéphane Bronner
      • Sylvie Binda

    • PubMed: 37894159
    • DOI: 10.3390/microorganisms11102501

    4 Insights on

    • Improved Intestinal Health
    • Reduced Risk of Infant Health Problems
    • Improved Infant Gut Microbiota Restoration
    • Improved Infant Health

    • Low evidence

  • Maternal supplementation with Limosilactobacillus reuteri FN041 for preventing infants with atopic dermatitis: study protocol for a randomized controlled trial

    • 2023-10-05
    • RCT · n = 840
    • Frontiers in Microbiology 14
    • • Renqiang Yu
      • Yizhe Ma
      • Zichen Luo
      • Ce Qi
      • Anni Xie
      • Yifan Jiang
      • Baoli Zhu
      • Jin Sun

    • PubMed: 37869669
    • DOI: 10.3389/fmicb.2023.1267448

    1 Insight on

    • Reduced Incidence of Atopic Dermatitis

    • High evidence
    • Large Human Trial
• October 9

  • Superoxide dismutase for bronchopulmonary dysplasia in preterm infants.

    • 2023-10-09
    • Systematic Review · n = 380
    • The Cochrane database of systematic reviews 2023(10)
    • • Martina Albertella
      • Rahul R Gentyala
      • Themistoklis Paraskevas
      • Danielle Ehret
      • Matteo Bruschettini
      • Roger Soll

    • PubMed: 37811631
    • DOI: 10.1002/14651858.cd013232.pub2

    4 Insights on

    • Reduced Mortality Rate
    • Reduced Bronchopulmonary Dysplasia
    • Reduced Neonatal Mortality
    • Reduced Retinopathy of Prematurity

    • High evidence
• October 12

  • Ligilactobacillus salivarius 7247 Strain: Probiotic Properties and Anti-Salmonella Effect with Prebiotics.

    • 2023-10-12
    • Antibiotics (Basel, Switzerland) 12(10)
    • • Vyacheslav M Abramov
      • Igor V Kosarev
      • Andrey V Machulin
      • Evgenia I Deryusheva
      • Tatiana V Priputnevich
      • Alexander N Panin
      • Irina O Chikileva
      • Tatiana N Abashina
      • Ashot M Manoyan
      • Anna A Ahmetzyanova
      • Olga E Ivanova
      • Tigran T Papazyan
      • Ilia N Nikonov
      • Nataliya E Suzina
      • Vyacheslav G Melnikov
      • Valentin S Khlebnikov
      • Vadim K Sakulin
      • Vladimir A Samoilenko
      • Alexey B Gordeev
      • Gennady T Sukhikh
      • Vladimir N Uversky

    • PubMed: 37887236
    • DOI: 10.3390/antibiotics12101535

    3 Insights on

    • Reduced Salmonella typhimurium Adhesion
    • Reduced Pathogenic Bacterial Growth
    • Reduced Salmonella Activity

    • Low evidence

  • The Use of Fibers, Herbal Medicines and Spices in Children with Irritable Bowel Syndrome: A Narrative Review.

    • 2023-10-12
    • Review
    • Nutrients 15(20)
    • • Daniela Pop
      • Radu Samuel Pop
      • Dorin Farcău

    • PubMed: 37892426
    • DOI: 10.3390/nu15204351

    1 Insight on

    • Reduced Irritable Bowel Syndrome Symptoms

    • Moderate evidence
    • Rigorous Journal
• October 18

  • Pre-medication with simethicone and N-acetyl cysteine for improving mucosal visibility during upper gastrointestinal endoscopy: A randomized controlled trial.

    • 2023-10-18
    • RCT · n = 800
    • Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 43(5)
    • • Zaheer Nabi
      • Mohan Vamsi
      • Rajesh Goud
      • Mahiboob Sayyed
      • Jahangeer Basha
      • Palle Manohar Reddy
      • Rithesh Reddy
      • Praveen Reddy
      • Chaithanya Manchu
      • Santosh Darisetty
      • Rajesh Gupta
      • Manu Tandan
      • Guduru Venkat Rao
      • D Nageshwar Reddy

    • PubMed: 37848768
    • DOI: 10.1007/s12664-023-01459-0

    2 Insights on

    • Improved Mucosal Visibility
    • Increased Lesion Detection Rate

    • High evidence
    • Large Human Trial
• October 26

  • Effects of Flavonoid Supplementation on Athletic Performance in Healthy Adults: A Systematic Review and Meta-Analysis.

    • 2023-10-26
    • Meta-Analysis · n = 22
    • Nutrients 15(21)
    • • Ying Wang
      • Zhuang Tian
      • Zhenyu Li
      • Jae Cheol Kim

    • PubMed: 37960199
    • DOI: 10.3390/nu15214547

    2 Insights on

    • Improved Athletic Performance
    • Improved Exercise Tolerance

    • High evidence
    • Rigorous Journal

  • Effect of Lactobacillus kefiri, in Conjunction with PENS T6 and a Hypocaloric Diet, on Weight Loss, Hypertension and Laboratory Glycemic and Lipid Profile

    • 2023-10-26
    • RCT
    • Nutrients 15(21)
    • • Jaime Ruiz-Tovar
      • C. Llavero
      • M. Fernández-Contreras

    • PubMed: 37960202
    • DOI: 10.3390/nu15214549

    8 Insights on

    • Improved Gut Microbiota Composition
    • Reduced Body Weight
    • Improved Lipid Profile
    • Increased Weight Reduction
    • Improved Glycemic Control
    • Improved Gut Microbiome Composition
    • Improved Blood Lipid Profile
    • Increased Weight Loss

    • High evidence
• October 27

  • Eight Weeks of Bifidobacterium lactis BL-99 Supplementation Improves Lipid Metabolism and Sports Performance through Short-Chain Fatty Acids in Cross-Country Skiers: A Preliminary Study

    • 2023-10-27
    • RCT · n = 16
    • Nutrients 15(21)
    • • Tie-hui Li
      • Zihan Rui
      • Letian Mao
      • Yashan Chang
      • Jing Shao
      • Yue Chen
      • Qi Han
      • Xuemi Sui
      • Nan An
      • Haoqiu Li
      • Haotian Feng
      • Tao Jiang
      • Qirong Wang

    • PubMed: 37960207
    • DOI: 10.3390/nu15214554

    10 Insights on

    • Improved Lipid Metabolism
    • Reduced LDL Cholesterol
    • Increased Short-Chain Fatty Acid Production
    • Improved Exercise Performance
    • Increased Beneficial Gut Bacteria
    • Increased Abundance of Bifidobacterium animalis
    • Improved VO2 Max
    • Improved Knee Joint Extensor Strength
    • Reduced Bile Acid Levels
    • Improved Sports Performance

    • High evidence
• October 28

  • Postbiotic Fractions of Probiotics Lactobacillus plantarum 299v and Lactobacillus rhamnosus GG Show Immune-Modulating Effects.

    • 2023-10-28
    • Cells 12(21)
    • • Agnieszka Magryś
      • Mateusz Pawlik

    • PubMed: 37947616
    • DOI: 10.3390/cells12212538

    5 Insights on

    • Reduced Intestinal Inflammation
    • Maintained Intestinal Barrier Function
    • Increased Anti-Inflammatory Cytokine IL-10
    • Maintained Intestinal Barrier Integrity
    • Modulated IL-18-Related Immune Response

    • Low evidence

  • Prebiotics, Probiotics, and Synbiotics-A Research Hotspot for Pediatric Obesity.

    • 2023-10-28
    • Review
    • Microorganisms 11(11)
    • • Reka Borka Balas
      • Lorena Elena Meliț
      • Ancuța Lupu
      • Vasile Valeriu Lupu
      • Cristina Oana Mărginean

    • PubMed: 38004665
    • DOI: 10.3390/microorganisms11112651

    3 Insights on

    • Reduced Body Mass Index
    • Improved Glucose Metabolism
    • Improved Blood Lipid Content

    • Low evidence
• October 30

  • Invertebrate C1q Domain-Containing Proteins: Molecular Structure, Functional Properties and Biomedical Potential.

    • 2023-10-30
    • Review
    • Marine drugs 21(11)
    • • Andrei Grinchenko
      • Ivan Buriak
      • Vadim Kumeiko

    • PubMed: 37999394
    • DOI: 10.3390/md21110570

    1 Insight on

    • No Human Health Outcome Reported

    • Low evidence
• Undated – 4 supplement studies

  • Efficacy and safety of Lacticaseibacillus paracasei Lpc-37® in students facing examination stress: A randomized, triple-blind, placebo-controlled clinical trial (the ChillEx study).

    • 2023-10
    • RCT
    • Brain, behavior, & immunity - health 32
    • • Sanna M Mäkelä
      • Síle M Griffin
      • Jenni Reimari
      • Kara C Evans
      • Ashley A Hibberd
      • Nicolas Yeung
      • Alvin Ibarra
      • Jouni Junnila
      • Jari Turunen
      • Ronnie Beboso
      • Balgit Chhokar
      • Timothy G Dinan
      • John Cryan
      • Elaine Patterson

    • PubMed: 37662485
    • DOI: 10.1016/j.bbih.2023.100673

    4 Insights on

    • Reduced Circadian Sleep Disturbance
    • Reduced Sleep Duration
    • Reduced Alertness
    • No Reduction in Stress or Anxiety

    • High evidence

  • Probiotic-related Clostridium butyricum bacteremia: a case report and literature review.

    • 2023-10
    • Review
    • Anaerobe 83
    • • Kazuhiro Ishikawa
      • Ryo Hasegawa
      • Koko Shibutani
      • Yumiko Mikami
      • Fujimi Kawai
      • Takahiro Matsuo
      • Yuki Uehara
      • Nobuyoshi Mori

    • PubMed: 37544356
    • DOI: 10.1016/j.anaerobe.2023.102770

    1 Insight on

    • Reduced Bacteremia

    • Low evidence

  • Effects of Synbiotic-Containing Bacillus coagulans (GBI-30) on the Cardiovascular Status of Patients With Polycystic Ovary Syndrome: A Triple-blinded, Randomized, Placebo-controlled Study.

    • 2023-10
    • RCT · n = 72
    • Clinical therapeutics 45(10)
    • • Zahra Hariri
      • Zahra Yari
      • Sedighe Hoseini
      • Afsaneh Mehrnami
      • Khadijeh Abhari
      • Golbon Sohrab

    • PubMed: 37640616
    • DOI: 10.1016/j.clinthera.2023.07.024

    3 Insights on

    • Reduced Atherogenic Index
    • Reduced C-Reactive Protein Levels
    • Improved Blood Lipid Profile

    • High evidence

  • Ayurvedic and herbal plaque control agents in gingivitis: A systematic review and meta-analysis of randomized controlled trials.

    • 2023-10
    • Review · n = 806
    • Journal of education and health promotion 12(1)
    • • Danish Javed
      • Ashish Kumar Dixit
      • Sana Anwar
      • Anshul Rai
      • Kawal Krishan

    • PubMed: 38144032
    • DOI: 10.4103/jehp.jehp_204_23

    1 Insight on

    • Reduced Plaque Index

    • High evidence