April 2024 Supplement Research Papers

• April 2

  • Efficacy of Bifidobacterium bifidum G9-1 in improving quality of life in patients with chronic constipation: a prospective intervention study

    • 2024-04-02
    • Bioscience of Microbiota, Food and Health 40(2)
    • • A. Fuyuki
      • T. Higurashi
      • Takaomi Kessoku
      • K. Ashikari
      • Tsutomu Yoshihara
      • Noboru Misawa
      • Michihiro Iwaki
      • Takashi Kobayashi
      • H. Ohkubo
      • M. Yoneda
      • Haruki Usuda
      • K. Wada
      • A. Nakajima

    • PubMed: 33996367
    • DOI: 10.12938/bmfh.2020-073

    8 Insights on

    • Improved Bowel Movement Frequency
    • Reduced Straining
    • Improved Stool Consistency
    • Increased Bowel Movement Frequency
    • Improved Quality of Life
    • Increased Butyrate Levels
    • Increased Sarcina Levels
    • Reduced Methane Metabolism

    • Low evidence
    • Rigorous Journal
• April 3

  • L-carnitine decreases myocardial injury in children undergoing open-heart surgery: A randomized controlled trial.

    • 2024-04-03
    • RCT · n = 60
    • European journal of pediatrics 183(6)
    • • Wael El Feky
      • Dalia El-Afify
      • Dina Abdelhai
      • Mohamed Elkashlan
      • Ahmed Fakhreldin
      • Doaa El Amrousy

    • PubMed: 38568244
    • DOI: 10.1007/s00431-024-05534-2

    8 Insights on

    • Reduced Malondialdehyde Level
    • Increased Superoxide Dismutase Level
    • Reduced Fas Level
    • Reduced Caspase-3 Level
    • Reduced Creatine Kinase-MB Level
    • Reduced Troponin I Level
    • Improved Left Ventricular Ejection Fraction
    • Improved Left Ventricular Global Longitudinal Strain

    • High evidence
• April 11

  • Production of probiotic fermented salami using Lacticaseibacillus rhamnosus, Lactiplantibacillus plantarum, and Bifidobacterium lactis.

    • 2024-04-11
    • Journal of food science 89(5)
    • • Olcay Tukel
      • Ilkin Sengun

    • PubMed: 38602050
    • DOI: 10.1111/1750-3841.17058

    1 Insight on

    • Improved Consumer Acceptance

    • Low evidence

  • [Phytotherapeutic recommendations in medical guidelines for the treatment of gastroenterological diseases - a systematic review].

    • 2024-04-11
    • Systematic Review
    • Zeitschrift fur Gastroenterologie 62(07)
    • • Sandra Utz
      • Miriam Bittel
      • Jost Langhorst

    • PubMed: 38604221
    • DOI: 10.1055/a-2279-5045

    7 Insights on

    • Improved Bowel Movement Frequency
    • Reduced Flatulence
    • Reduced Abdominal Pain
    • Improved Irritable Bowel Syndrome Symptoms
    • Maintained Remission in Ulcerative Colitis
    • Induced Remission in Ulcerative Colitis
    • Improved Crohn Disease Symptom

    • High evidence
• April 12

  • Selection of Fermentation Supernatant from Probiotic Strains Exhibiting Intestinal Epithelial Barrier Protective Ability and Evaluation of Their Effects on Colitis Mouse and Weaned Piglet Models.

    • 2024-04-12
    • Nutrients 16(8)
    • • Solomon Abrehame
      • Man-Yun Hung
      • Yu-Yi Chen
      • Yu-Tse Liu
      • Yung-Tsung Chen
      • Fang-Chueh Liu
      • Yu-Chun Lin
      • Yen-Po Chen

    • PubMed: 38674829
    • DOI: 10.3390/nu16081138

    4 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Colitis Severity
    • Improved Gut Barrier Function
    • Improved Colitis

    • Low evidence
    • Rigorous Journal
• April 15

  • Effectiveness of Probiotic Use in Alleviating Symptoms of Irritable Bowel Syndrome: A Systematic Review.

    • 2024-04-15
    • Review
    • Cureus 16(4)
    • • Lotanna Umeano
      • Sadaf Iftikhar
      • Sarah F Alhaddad
      • Christian N Paulsingh
      • Muhammad Faisal Riaz
      • Gourav Garg
      • Lubna Mohammed

    • PubMed: 38752062
    • DOI: 10.7759/cureus.58306

    1 Insight on

    • Reduced Irritable Bowel Syndrome Symptoms

    • Low evidence

  • Randomised, Placebo-Controlled Investigation of the Impact of Probiotic Consumption on Gut Microbiota Diversity and the Faecal Metabolome in Seniors.

    • 2024-04-15
    • RCT · n = 45
    • Microorganisms 12(4)
    • • Gabriella C van Zanten
      • Anne Lundager Madsen
      • Christian C Yde
      • Lukasz Krych
      • Nicolas Yeung
      • Markku T Saarinen
      • Witold Kot
      • Henrik Max Jensen
      • Morten A Rasmussen
      • Arthur C Ouwehand
      • Dennis S Nielsen

    • PubMed: 38674741
    • DOI: 10.3390/microorganisms12040796

    3 Insights on

    • Reduced Flatulence
    • Unchanged Gut Microbiota Diversity
    • No Change in Fecal Metabolome

    • High evidence
• April 17

  • The Impact of Vitamin Deficiencies on Oral Manifestations in Children.

    • 2024-04-17
    • Review
    • Dentistry journal 12(4)
    • • Stjepanka Lešić
      • Zrinka Ivanišević
      • Bruno Špiljak
      • Matej Tomas
      • Magdalena Šoštarić
      • Aleksandar Včev

    • PubMed: 38668021
    • DOI: 10.3390/dj12040109

    8 Insights on

    • Improved Oral Mucositis
    • Improved Blood Clotting
    • Reduced Enamel Hypomineralization
    • Reduced Aphthous Stomatitis
    • Reduced Gingival Petechiae
    • Reduced Oral Candidiasis Risk
    • Reduced Enamel Issue
    • Reduced Dental Disease Susceptibility

    • Low evidence

  • How does active yeast supplementation reduce the deleterious effects of aflatoxins in Wistar rats? A radiolabeled assay and histopathological study.

    • 2024-04-17
    • World journal of microbiology & biotechnology 40(6)
    • • Pietro Sica
      • Maria Antonia Domingues
      • Layna Amorim Mota
      • Alana Uchôa Pinto
      • Ana Angelita Sampaio Baptista
      • Jorge Horii
      • Adibe Luiz Abdalla
      • Antonio Sampaio Baptista

    • PubMed: 38630373
    • DOI: 10.1007/s11274-024-03981-5

    2 Insights on

    • Reduced Liver Damage
    • No Significant Change in Aflatoxin Distribution or Metabolism

    • Low evidence
    • Animal Study
• April 18

  • Hormetic Nutrition and Redox Regulation in Gut-Brain Axis Disorders.

    • 2024-04-18
    • Review
    • Antioxidants (Basel, Switzerland) 13(4)
    • • Maria Scuto
      • Francesco Rampulla
      • Giuseppe Maria Reali
      • Sestina Maria Spanò
      • Angela Trovato Salinaro
      • Vittorio Calabrese

    • PubMed: 38671931
    • DOI: 10.3390/antiox13040484

    1 Insight on

    • Improved Gut Microbiota Balance

    • Low evidence
• April 20

  • Streptococcus salivarius K12 Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors: A Randomized Controlled Trial.

    • 2024-04-20
    • RCT · n = 160
    • Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42(12)
    • • Xingchen Peng
      • Zixia Li
      • Yiyan Pei
      • Shuhao Zheng
      • Jinchi Liu
      • Jingjing Wang
      • Ruidan Li
      • Xin Xu

    • PubMed: 38215354
    • DOI: 10.1200/jco.23.00837

    2 Insights on

    • Reduced Oral Mucositis Severity
    • Delayed Oral Mucositis Onset

    • High evidence
    • Large Human Trial

  • L-Carnitine in the Treatment of Psychiatric and Neurological Manifestations: A Systematic Review.

    • 2024-04-20
    • Systematic Review · n = 1,479
    • Nutrients 16(8)
    • • Wenbo Wang
      • Da Pan
      • Qi Liu
      • Xiangjun Chen
      • Shaokang Wang

    • PubMed: 38674921
    • DOI: 10.3390/nu16081232

    16 Insights on

    • Improved Attention Span
    • Improved Delayed Memory
    • Improved Hepatic Encephalopathy
    • Improved Alzheimer Disease
    • Improved Carpal Tunnel Syndrome
    • Improved Migraine
    • Improved Neurofibromatosis
    • Improved Peripheral Nervous System Disease
    • Improved Raynaud's Syndrome
    • Improved Stroke Outcome
    • Improved Amyotrophic Lateral Sclerosis Outcome
    • Improved Ataxia
    • Improved Depression Symptoms
    • Improved Chronic Fatigue Syndrome
    • Improved Down Syndrome
    • Reduced Sciatica Symptoms

    • High evidence
    • Rigorous Journal
• April 25

  • Bacteriocins: potentials and prospects in health and agrifood systems.

    • 2024-04-25
    • Review
    • Archives of microbiology 206(5)
    • • Rine Christopher Reuben
      • Carmen Torres

    • PubMed: 38662051
    • DOI: 10.1007/s00203-024-03948-y

    2 Insights on

    • Improved Gastrointestinal Health
    • Improved Gut Health

    • Low evidence
• April 29

  • Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.

    • 2024-04-29
    • Review
    • Cureus 16(4)
    • • Alexander Rawji
      • Morgan R Peltier
      • Kelly Mourtzanakis
      • Samreen Awan
      • Junaid Rana
      • Nitin J Pothen
      • Saba Afzal

    • PubMed: 38817505
    • DOI: 10.7759/cureus.59317

    2 Insights on

    • Reduced Anxiety
    • Improved Sleep Quality

    • Low evidence

  • Effect of Peanut Butter Intake on Sleep Health in Firefighters: A Randomized Controlled Trial.

    • 2024-04-29
    • RCT
    • International journal of environmental research and public health 21(5)
    • • Tiffany J Oberther
      • Andrew R Moore
      • Austin A Kohler
      • David H Shuler
      • Nicole Peritore
      • Angelia M Holland-Winkler

    • PubMed: 38791786
    • DOI: 10.3390/ijerph21050571

    11 Insights on

    • Improved Attention Span
    • Improved Sleep Quality
    • Reduced Sleep Latency
    • Improved Mood
    • Improved Sleep Efficiency
    • Increased Time in Bed
    • Increased Time Asleep
    • Reduced Wake After Sleep Onset
    • Reduced Nighttime Awakening
    • Reduced Awake Time
    • Improved Focus

    • High evidence
• April 30

  • Effectiveness of Psychobiotics in the Treatment of Psychiatric and Cognitive Disorders: A Systematic Review of Randomized Clinical Trials.

    • 2024-04-30
    • Systematic Review · n = 3,353
    • Nutrients 16(9)
    • • Freiser Eceomo Cruz Mosquera
      • Santiago Lizcano Martinez
      • Yamil Liscano

    • PubMed: 38732599
    • DOI: 10.3390/nu16091352

    1 Insight on

    • Improved Depressive Symptoms

    • High evidence
    • Rigorous Journal

  • Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity.

    • 2024-04-30
    • Review
    • Nutrients 16(9)
    • • A K M Humayun Kober
      • Sudeb Saha
      • Mutamed Ayyash
      • Fu Namai
      • Keita Nishiyama
      • Kazutoyo Yoda
      • Julio Villena
      • Haruki Kitazawa

    • PubMed: 38732619
    • DOI: 10.3390/nu16091373

    10 Insights on

    • Improved Insulin Sensitivity
    • Reduced Body Mass Index
    • Reduced Leptin Levels
    • Improved Lipid Metabolism
    • Increased Adiponectin Levels
    • Reduced TNF-α Levels
    • Reduced Inflammation
    • Reduced Weight Gain
    • Reduced IL-6 Levels
    • Reduced MCP-1/CCL2 Levels

    • Moderate evidence
    • Rigorous Journal
• Undated – 2 supplement studies

  • Maternal mood, anxiety and mental health functioning after combined myo-inositol, probiotics, micronutrient supplementation from preconception: Findings from the NiPPeR RCT.

    • 2024-04
    • RCT · n = 630
    • Psychiatry research 334
    • • Sarah El-Heis
      • Sheila J Barton
      • Hsin Fang Chang
      • Heidi Nield
      • Vanessa Cox
      • Sevasti Galani
      • Wayne Cutfield
      • Shiao-Yng Chan
      • Keith M Godfrey

    • PubMed: 38402742
    • DOI: 10.1016/j.psychres.2024.115813

    3 Insights on

    • Reduced Anxiety Symptoms
    • Improved Mental Health
    • Improved Symptoms

    • High evidence
    • Large Human Trial

  • The effect of probiotic Bifidobacterium lactis Bl-04 on innate antiviral responses invitro.

    • 2024-04
    • Heliyon 10(8)
    • • Sinikka Latvala
      • Markus J Lehtinen
      • Sanna M Mäkelä
      • Derek Nedveck
      • Bryan Zabel
      • Ilmari Ahonen
      • Liisa Lehtoranta
      • Ronald B Turner
      • Jenni Liljavirta

    • PubMed: 38665561
    • DOI: 10.1016/j.heliyon.2024.e29588

    5 Insights on

    • Reduced Viral Load
    • Enhanced Innate Immune Response
    • Reduced Risk of Upper Respiratory Tract Infections
    • Reduced Rhinovirus Nasal Lavage Titer
    • Enhanced Innate Antiviral Immune Response

    • Low evidence