July 2024 Supplement Research Papers

• July 2

  • The Efficacy of Probiotics, Prebiotics, Synbiotics, and Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.

    • 2024-07-02
    • Systematic Review
    • Nutrients 16(13)
    • • Youhe Wu
      • Yuetong Li
      • Qi Zheng
      • Lanjuan Li

    • PubMed: 38999862
    • DOI: 10.3390/nu16132114

    1 Insight on

    • Improved IBS Symptom Score

    • High evidence
    • Rigorous Journal

  • Panax notoginseng: Pharmacological Aspects and Toxicological Issues.

    • 2024-07-02
    • Review
    • Nutrients 16(13)
    • • Cesare Mancuso

    • PubMed: 38999868
    • DOI: 10.3390/nu16132120

    1 Insight on

    • Improved Cardiac Function

    • Moderate evidence
    • Rigorous Journal

  • Intestinal microbiota imbalance resulted by anti-Toxoplasma gondii immune responses aggravate gut and brain injury.

    • 2024-07-02
    • Parasites & vectors 17(1)
    • • Jiating Chen
      • Chi Zhang
      • Zihan Yang
      • Weiling Wu
      • Weihao Zou
      • Zixuan Xin
      • Shuyu Zheng
      • Runchun Liu
      • Lili Yang
      • Hongjuan Peng

    • PubMed: 38956725
    • DOI: 10.1186/s13071-024-06349-8

    3 Insights on

    • Improved Intestinal Barrier Function
    • Increased Levels of Indole-3-Lactic Acid
    • Reduced Toxoplasma gondii Burden

    • Low evidence
    • Animal Study
• July 3

  • Viability-PCR for the selective detection of Lactobacillus acidophilus and Bifidobacterium bifidum in live bacteria-containing products.

    • 2024-07-03
    • Frontiers in microbiology 15
    • • Stefania Catone
      • Serena Iannantuono
      • Domenico Genovese
      • Christina Von Hunolstein
      • Giovanna Franciosa

    • PubMed: 39021625
    • DOI: 10.3389/fmicb.2024.1400529

    1 Insight on

    • Increased Probiotic Bacterial Count

    • Low evidence
• July 5

  • Production, Purification, and Characterization of a Novel Exopolysaccharide from Probiotic Lactobacillus amylovorus: MTCC 8129.

    • 2024-07-05
    • Indian journal of microbiology 64(3)
    • • Janani Murugu
      • Rajnish Narayanan

    • PubMed: 39282197
    • DOI: 10.1007/s12088-024-01346-y

    3 Insights on

    • Improved Antioxidant Activity
    • Improved Functional Properties of Food
    • Improved Emulsification Properties

    • Low evidence
• July 8

  • Effect of N-acetyl cysteine in children with metabolic dysfunction-associated steatotic liver disease-A pilot study.

    • 2024-07-08
    • RCT · n = 13
    • Journal of pediatric gastroenterology and nutrition 79(3)
    • • P Babu Balagopal
      • Rohit Kohli
      • Vikas Uppal
      • Lauren Averill
      • Chetan Shah
      • Katherine McGoogan
      • Matthew Di Guglielmo
      • Michael Goran
      • Md Jobayer Hossain

    • PubMed: 38973318
    • DOI: 10.1002/jpn3.12312

    4 Insights on

    • Improved Insulin Sensitivity
    • Reduced Liver Enzyme Levels
    • Reduced Inflammation
    • Reduced Oxidative Stress

    • High evidence

  • Research Progress on the Correlation of Atopic Dermatitis with Gut Microbiota.

    • 2024-07-08
    • Review
    • Clinical, cosmetic and investigational dermatology 17
    • • Qiuyu Mao
      • Xinyi Wang
      • Haibin Cai
      • Jingyi Yang
      • Yiwen Zhang
      • Wei Min
      • Qihong Qian
      • Yibin Zeng

    • PubMed: 39006130
    • DOI: 10.2147/ccid.s442551

    1 Insight on

    • Improved Atopic Dermatitis Symptoms

    • Low evidence

  • Impact of L-theanine and L-tyrosine on markers of stress and cognitive performance in response to a virtual reality based active shooter training drill.

    • 2024-07-08
    • RCT · n = 28
    • Stress (Amsterdam, Netherlands) 27(1)
    • • Matthew J McAllister
      • M Hunter Martaindale
      • Courtney C Dillard
      • Rory McCullough

    • PubMed: 38975711
    • DOI: 10.1080/10253890.2024.2375588

    5 Insights on

    • Reduced Anxiety
    • Increased Salivary sIgA Levels
    • Reduced Heart Rate
    • Reduced Salivary Alpha-Amylase Level
    • Reduced Missed Response

    • High evidence
• July 9

  • Effect of Low-Dose Mulberry Fruit Extract on Postprandial Glucose and Insulin Responses: A Randomized Pilot Trial in Individuals with Type 2 Diabetes.

    • 2024-07-09
    • RCT
    • Nutrients 16(14)
    • • David J Mela
      • Marjan Alssema
      • Harry Hiemstra
      • Anne-Roos Hoogenraad
      • Tanvi Kadam

    • PubMed: 39064619
    • DOI: 10.3390/nu16142177

    2 Insights on

    • Reduced Postprandial Glucose Response
    • Reduced Postprandial Insulin Response

    • High evidence
    • Rigorous Journal
• July 11

  • The Role of Lactobacillus plantarum in Reducing Obesity and Inflammation: A Meta-Analysis.

    • 2024-07-11
    • Meta-Analysis
    • International journal of molecular sciences 25(14)
    • • Chen-Pi Li
      • Chin-Chang Chen
      • Yao Hsiao
      • Chieh-Hsin Kao
      • Chin-Chu Chen
      • Hao-Jan Yang
      • Ru-Yin Tsai

    • PubMed: 39062848
    • DOI: 10.3390/ijms25147608

    5 Insights on

    • Reduced Body Mass Index
    • Reduced Interleukin-6 Levels
    • Reduced Body Weight
    • Reduced Abdominal Fat
    • Reduced C-Reactive Protein Levels

    • High evidence
    • Rigorous Journal
• July 12

  • Osteoporotic osseointegration: therapeutic hallmarks and engineering strategies.

    • 2024-07-12
    • Review
    • Theranostics 14(10)
    • • Jiayao Chen
      • Zhuowen Hao
      • Hanke Li
      • Jianping Wang
      • Tianhong Chen
      • Ying Wang
      • Guang Shi
      • Junwu Wang
      • Zepu Wang
      • Zheyuan Zhang
      • Jingfeng Li

    • PubMed: 38994021
    • DOI: 10.7150/thno.96516

    2 Insights on

    • Osteoporosis Treatment Strategy
    • Improved Bone Regeneration

    • Low evidence
• July 15

  • Kavalactones support motivation to move during intensive training in males preparing for military special operations forces.

    • 2024-07-15
    • RCT
    • Journal of the International Society of Sports Nutrition 21(1)
    • • Sheena Y Smith
      • Carlos F Aylwin
      • Tyler F Daniels
      • Jennifer L Greer
      • Laura J Kunces
      • Loukia Lili
      • Stephen M Phipps
      • Caleb M Schmidt
      • Julian C Schmidt
      • Michael A Schmidt

    • PubMed: 39010683
    • DOI: 10.1080/15502783.2024.2377194

    5 Insights on

    • Improved Sleep Quality
    • Reduced Cortisol Levels
    • Reduced DASS-21 Score
    • Improved Motivation to Move
    • Reduced Cravings for Rest

    • High evidence
• July 16

  • Lactobacillus acidophilus inhibits the TNF-α-induced increase in intestinal epithelial tight junction permeability via a TLR-2 and PI3K-dependent inhibition of NF-κB activation.

    • 2024-07-16
    • Frontiers in immunology 15
    • • Mohammad Haque
      • Lauren Kaminsky
      • Raz Abdulqadir
      • Jessica Engers
      • Evgeny Kovtunov
      • Manmeet Rawat
      • Rana Al-Sadi
      • Thomas Y Ma

    • PubMed: 39081324
    • DOI: 10.3389/fimmu.2024.1348010

    1 Insight on

    • Reduced Epithelial Permeability

    • Low evidence

  • Comparative Effects of Gymnema sylvestre and Berberine on Adipokines, Body Composition, and Metabolic Parameters in Obese Patients: A Randomized Study.

    • 2024-07-16
    • RCT
    • Nutrients 16(14)
    • • Cindy Bandala
      • Jazmín Carro-Rodríguez
      • Noemí Cárdenas-Rodríguez
      • Itzel Peña-Montero
      • Modesto Gómez-López
      • Ana Paola Hernández-Roldán
      • Juan Carlos Huerta-Cruz
      • Felipe Muñoz-González
      • Iván Ignacio-Mejía
      • Brayan Domínguez
      • Eleazar Lara-Padilla

    • PubMed: 39064727
    • DOI: 10.3390/nu16142284

    7 Insights on

    • Reduced Body Weight
    • Reduced Blood Pressure
    • Reduced Fasting Glucose
    • Reduced Visfatin Level
    • Reduced Apelin Gene Expression
    • Increased Omentin Level
    • Reduced Resistin Gene Expression

    • High evidence
    • Rigorous Journal
• July 18

  • A Three-Month Probiotic (the Streptococcus salivarius M18 Strain) Supplementation Decreases Gingival Bleeding and Plaque Accumulation: A Randomized Clinical Trial.

    • 2024-07-18
    • RCT · n = 60
    • Dentistry journal 12(7)
    • • Ksenia Babina
      • Dilara Salikhova
      • Irina Makeeva
      • Alexandr Zaytsev
      • Inna Sokhova
      • Sevil Musaeva
      • Maria Polyakova
      • Nina Novozhilova

    • PubMed: 39057009
    • DOI: 10.3390/dj12070222

    3 Insights on

    • Reduced Gingival Bleeding
    • Reduced Formation of Dental Plaque
    • Reduced Gingival Inflammation

    • High evidence
• July 19

  • Safety and efficacy of L-Glutamine in reducing the frequency of acute complications among patients with sickle cell disease: A randomized controlled study.

    • 2024-07-19
    • RCT
    • Annals of hematology 103(9)
    • • Fatma Soliman Elsayed Ebeid
      • Nihal Hussien Aly
      • Naglaa Mohammed Shaheen
      • Samah Mohammed Ahmed Abdellatif
      • Ahmed Ashraf Mahmoud Okba
      • Nada Ayman Gad
      • Sara Mostafa Makkeyah

    • PubMed: 39028356
    • DOI: 10.1007/s00277-024-05877-8

    3 Insights on

    • Reduced Vaso-Occlusive Crisis Frequency
    • Reduced Hospitalization for Vaso-Occlusive Crisis
    • Improved Cerebral Blood Flow Velocity

    • High evidence
• July 22

  • Lactobacillus reuteri DSM 17938 Improves Feeding Intolerance in Preterm Infants

    • 2024-07-22
    • RCT · n = 94
    • Pediatric Gastroenterology, Hepatology & Nutrition 22(6)
    • • Risma K Kaban
      • Wardhana
      • B. Hegar
      • R. Rohsiswatmo
      • S. Handryastuti
      • Novie Amelia
      • D. Muktiarti
      • F. Indrio
      • Y. Vandenplas

    • PubMed: 31777720
    • DOI: 10.5223/pghn.2019.22.6.545

    3 Insights on

    • Reduced Colitis-Related Mortality
    • Reduced Feeding Intolerance
    • Reduced Prevalence of Necrotizing Enterocolitis

    • High evidence
    • Rigorous Journal

  • The effect of probiotics and casein supplementation on aerobic capacity parameters of male soccer players.

    • 2024-07-22
    • RCT
    • Journal of the International Society of Sports Nutrition 21(1)
    • • Babak Imanian
      • Mohammad Hemmatinafar
      • Farhad Daryanoosh
      • Negar Koureshfard
      • Reza Sadeghi
      • Alireza Niknam
      • Rasoul Rezaei
      • Ali Qashqaei

    • PubMed: 39039903
    • DOI: 10.1080/15502783.2024.2382165

    2 Insights on

    • Improved Aerobic Capacity
    • Increased Hypocapnic Hyperventilation Area Time

    • High evidence

  • The beneficial effect of probiotics in the prevention of irinotecan-induced diarrhea in colorectal cancer patients with colostomy: a pooled analysis of two probiotic trials (Probio-SK-003 and Probio-SK-005) led by Slovak Cooperative Oncology Group.

    • 2024-07-22
    • RCT · n = 279
    • Frontiers in oncology 14
    • • Michal Mego
      • Barbora Kasperova
      • Jozef Chovanec
      • Radoslav Danis
      • Maria Reckova
      • Branislav Bystricky
      • Peter Konkolovsky
      • Silvia Jurisova
      • Stefan Porsok
      • Vladimir Vaclav
      • Maria Wagnerova
      • Marian Stresko
      • Bibiana Brezinova
      • Dagmar Sutekova
      • Sona Ciernikova
      • Daniela Svetlovska
      • Lubos Drgona

    • PubMed: 39104721
    • DOI: 10.3389/fonc.2024.1438657

    1 Insight on

    • Reduced Diarrhea

    • High evidence

  • Effects of Hesperidin Supplementation on Cardiometabolic Markers: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

    • 2024-07-22
    • Meta-Analysis
    • Nutrition reviews 83(3)
    • • Zeinab Heidari
      • Fatemeh Farahmandpour
      • Hadi Bazyar
      • Fereshteh Pashayee-Khamene

    • PubMed: 39038797
    • DOI: 10.1093/nutrit/nuae084

    6 Insights on

    • Reduced Systolic Blood Pressure
    • Reduced Triglyceride Levels
    • Reduced LDL Cholesterol
    • Reduced Pro-inflammatory Cytokine Levels
    • Reduced Total Cholesterol
    • Reduced Fasting Blood Glucose

    • High evidence
• July 24

  • Postbiotics as Adjuvant Therapy in Cancer Care.

    • 2024-07-24
    • Review
    • Nutrients 16(15)
    • • Vyshnavy Balendra
      • Roberto Rosenfeld
      • Chiara Amoroso
      • Cecilia Castagnone
      • Maria Grazia Rossino
      • Ornella Garrone
      • Michele Ghidini

    • PubMed: 39125280
    • DOI: 10.3390/nu16152400

    1 Insight on

    • Improved Cancer-Related Health Outcome

    • Moderate evidence
    • Rigorous Journal
• July 25

  • Use of Streptococcus Salivarius K12 in a cohort of PFAPA patients.

    • 2024-07-25
    • Observational · n = 117
    • Frontiers in pediatrics 12
    • • Alessandra Spagnolo
      • Vincenzo Mileto
      • Adele Civino
      • Maria Cristina Maggio
      • Paolo Risso
      • Simona Sestito
      • Romina Gallizzi

    • PubMed: 39119192
    • DOI: 10.3389/fped.2024.1370544

    8 Insights on

    • Reduced Fever
    • Reduced Duration of Febrile Episodes
    • Reduced PFAPA Fever Episode Frequency
    • Reduced Episode Frequency
    • Reduced Episode Duration
    • Reduced Exudative Pharyngotonsillitis Frequency
    • Reduced Oral Aphthosis Frequency
    • Reduced Cervical Lymphadenopathy Frequency

    • High evidence
• July 29

  • Silk Sericin and Its Effect on Skin Wound Healing: A State of the Art.

    • 2024-07-29
    • Review
    • Macromolecular bioscience 24(10)
    • • Łukasz Mazurek
      • Mateusz Rybka
      • Jan Jurak
      • Jakub Frankowski
      • Marek Konop

    • PubMed: 39073276
    • DOI: 10.1002/mabi.202400145

    1 Insight on

    • Improved Wound Healing

    • Low evidence
• July 31

  • The effects of L-carnitine supplementation on cardiovascular risk factors in participants with impaired glucose tolerance and diabetes: a systematic review and dose-response meta-analysis.

    • 2024-07-31
    • Review · n = 2,900
    • Diabetology & metabolic syndrome 16(1)
    • • Rezvan Gheysari
      • Mahlagha Nikbaf-Shandiz
      • Amir Mehdi Hosseini
      • Niloufar Rasaei
      • Shabnam Hosseini
      • Hossein Bahari
      • Omid Asbaghi
      • Samira Rastgoo
      • Kian Goudarzi
      • Farideh Shiraseb
      • Reza Behmadi

    • PubMed: 39085907
    • DOI: 10.1186/s13098-024-01415-8

    11 Insights on

    • Reduced Body Mass Index
    • Reduced Tumor Necrosis Factor Alpha
    • Reduced Body Weight
    • Reduced Uric Acid Levels
    • Reduced Body Fat Percentage
    • Reduced Triglyceride Levels
    • Reduced LDL Cholesterol
    • Reduced Hemoglobin A1c
    • Reduced C-Reactive Protein Levels
    • Reduced Fasting Blood Glucose Levels
    • Improved Insulin Resistance

    • High evidence
• Undated – 2 supplement studies

  • The role of Bifidobacterium in longevity and the future of probiotics.

    • 2024-07
    • Review
    • Food science and biotechnology 33(9)
    • • Seockmo Ku
      • Md Ariful Haque
      • Min Ji Jang
      • Jaehyun Ahn
      • Deokyeong Choe
      • Jong Ik Jeon
      • Myeong Soo Park

    • PubMed: 39130652
    • DOI: 10.1007/s10068-024-01631-y

    2 Insights on

    • Improved Intestinal Barrier Function
    • Improved Immune Function

    • Low evidence

  • Effect of Egg-White Protein Alone or Combined With Niacin on Nutritional Status, and Phosphorus Control in Maintenance Hemodialysis Patients: A Randomized Controlled Trial.

    • 2024-07
    • RCT · n = 98
    • Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 34(4)
    • • Parisa Javadian
      • Niloofar Nematollahi
      • Ehsan Ghaedi
      • Shahram Tahmasebian
      • Ebrahim Saedi

    • PubMed: 38281653
    • DOI: 10.1053/j.jrn.2023.12.008

    4 Insights on

    • Increased Serum Albumin Levels
    • Reduced Serum Phosphorus Level
    • Improved Dialysis Adequacy
    • Increased Aspartate Aminotransferase Level

    • High evidence