June 2024 Supplement Research Papers

• June 1

  • Characterization of Antimicrobial Activities of Bifidobacterium lactis BB-12 and Their Inhibitory Effect Against Some Foodborne Pathogens.

    • 2024-06-01
    • Foodborne pathogens and disease 21(6)
    • • Fatemeh Roozbahani
      • Mohammad Ahanjan
      • Mona Moshiri
      • Saeid Abediankenari
      • Hamid Reza Goli
      • Maedeh Kakavan
      • Mehrdad Gholami

    • PubMed: 38578010
    • DOI: 10.1089/fpd.2023.0182

    2 Insights on

    • Reduced Pathogen Growth
    • Reduced Salmonella Typhimurium Activity

    • Low evidence

  • A Randomized Single-Blinded Phase II Trial Comparing Efficacy and Quality of Life of Topical Aloe Vera Gel Plus Urea Cream Versus Urea Cream Alone for Prevention of Hand Foot Syndrome in Cancer Patients Receiving Capecitabine.

    • 2024-06-01
    • RCT · n = 31
    • Asian Pacific journal of cancer prevention : APJCP 25(6)
    • • Lucksika Wanichtanom
      • Gorn Vrakornvoravuti
      • Metavee Boonsiri
      • Apisada Suthepwanon

    • PubMed: 38918684
    • DOI: 10.31557/apjcp.2024.25.6.2203

    2 Insights on

    • Improved Quality of Life
    • Reduced Hand Foot Syndrome Severity

    • High evidence
• June 3

  • Recent Advances in the Understanding of Stress Resistance Mechanisms in Probiotics: Relevance for the Design of Functional Food Systems.

    • 2024-06-03
    • Review
    • Probiotics and antimicrobial proteins 17(1)
    • • Ana Yanina Bustos
      • María Pía Taranto
      • Carla Luciana Gerez
      • Sofia Agriopoulou
      • Slim Smaoui
      • Theodoros Varzakas
      • Hesham Ali El Enshasy

    • PubMed: 38829565
    • DOI: 10.1007/s12602-024-10273-9

    3 Insights on

    • Improved Gastrointestinal Health
    • Improved Gut Health
    • Improved Stress Tolerance

    • Moderate evidence
    • Rigorous Journal

  • Effect of blueberry intervention on endothelial function: a systematic review and meta-analysis.

    • 2024-06-03
    • Systematic Review
    • Frontiers in physiology 15
    • • Bixin Deng
      • Yupeng Lei
      • Ruixi Zhou
      • Tiechao Ruan
      • Wenting Lu
      • Junjie Ying
      • Yan Yue
      • Dezhi Mu

    • PubMed: 38887319
    • DOI: 10.3389/fphys.2024.1368892

    3 Insights on

    • Reduced Diastolic Blood Pressure
    • Improved Flow-Mediated Dilation
    • Improved Reactive Hyperemia Index

    • High evidence
• June 6

  • The effect of psyllium on fasting blood sugar, HbA1c, HOMA IR, and insulin control: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials.

    • 2024-06-06
    • Meta-Analysis · n = 962
    • BMC endocrine disorders 24(1)
    • • Zeinab Gholami
      • Cain C T Clark
      • Zamzam Paknahad

    • PubMed: 38844885
    • DOI: 10.1186/s12902-024-01608-2

    1 Insight on

    • Reduced Hemoglobin A1c

    • High evidence
• June 10

  • Citrus depressa peel extract acts as a prebiotic to reduce lipid accumulation and modulate gut microbiota in obese mice.

    • 2024-06-10
    • Journal of food and drug analysis 32(2)
    • • Zheng-Yuan Su
      • Jie-An Liao
      • Ching-Ting Lin
      • Guor-Jien Wei
      • Yen-Chen Tung

    • PubMed: 38934690
    • DOI: 10.38212/2224-6614.3504

    3 Insights on

    • Improved Gut Microbiota Composition
    • Reduced Liver Lipid Accumulation
    • Modulated Gut Microbiota

    • Low evidence
• June 12

  • The Effect of Sargassum fusiforme and Fucus vesiculosus on Continuous Glucose Levels in Overweight Patients with Type 2 Diabetes Mellitus: A Feasibility Randomized, Double-Blind, Placebo-Controlled Trial.

    • 2024-06-12
    • RCT · n = 12
    • Nutrients 16(12)
    • • Karlijn A M Geurts
      • Sjoerd Meijer
      • Jeanine E Roeters van Lennep
      • Xi Wang
      • Behiye Özcan
      • Gardi Voortman
      • Hongbing Liu
      • Manuel Castro Cabezas
      • Kirsten A Berk
      • Monique T Mulder

    • PubMed: 38931192
    • DOI: 10.3390/nu16121837

    1 Insight on

    • Reduced Blood Glucose Level

    • High evidence
    • Rigorous Journal
• June 14

  • Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.

    • 2024-06-14
    • RCT · n = 119
    • Medicine 103(24)
    • • Wankiun Lee
      • Manho Kim

    • PubMed: 38875437
    • DOI: 10.1097/md.0000000000038067

    3 Insights on

    • Improved Mini-Mental State Examination Score
    • Improved Alzheimer Disease Assessment Scale-Cognitive Subscale Score
    • Improved Alzheimer Disease Assessment Scale-Noncognitive Subscale Score

    • High evidence
    • Large Human Trial
• June 17

  • Supplementing infant milk formula with a multi-strain synbiotic and osteopontin enhances colonic microbial colonization and modifies jejunal gene expression in lactating piglets.

    • 2024-06-17
    • Food & function 15(12)
    • • Laia Ferreres-Serafini
      • Susana Mª Martín-Orúe
      • Meritxell Sadurní
      • Jesús Jiménez
      • José Antonio Moreno-Muñoz
      • Lorena Castillejos

    • PubMed: 38807503
    • DOI: 10.1039/d4fo00489b

    1 Insight on

    • Reduced Duration of Diarrhea

    • Low evidence
    • Rigorous Journal

  • Effects of different natural products in patients with non-alcoholic fatty liver disease-A network meta-analysis of randomized controlled trials.

    • 2024-06-17
    • Review · n = 2,509
    • Phytotherapy research : PTR 38(7)
    • • Hongshuai Liu
      • Yufei Li
      • Yan Jin
      • Xin Li
      • Dongxian Wang
      • Xiaowen Yu
      • Zhenyuan Jiang
      • Guoliang Yin
      • Suwen Chen
      • Xin Zhang
      • Decheng Meng
      • Wenfei Yu
      • Wenyin Jiang
      • Fengxia Zhang

    • PubMed: 38886838
    • DOI: 10.1002/ptr.8182

    7 Insights on

    • Reduced Body Mass Index
    • Reduced Total Cholesterol Levels
    • Reduced Low-Density Lipoprotein Level
    • Reduced Triglyceride Levels
    • Increased HDL Cholesterol Levels
    • Reduced Aspartate Aminotransferase Levels
    • Reduced Alanine Aminotransferase Level

    • High evidence

  • Functional evaluation of pure natural edible Ferment: protective function on ulcerative colitis.

    • 2024-06-17
    • Frontiers in microbiology 15
    • • Yanjun Chen
      • Shengzhi Ye
      • Jiaolong Shi
      • Hao Wang
      • Guangxu Deng
      • Guangxian Wang
      • Shijie Wang
      • Qingbin Yuan
      • Lunan Yang
      • Tingyu Mou

    • PubMed: 38952444
    • DOI: 10.3389/fmicb.2024.1367630

    2 Insights on

    • Improved Gut Microbiota Composition
    • Reduced Ulcerative Colitis Symptoms

    • Low evidence
• June 19

  • Probiotic-Reduced Inflammaging in Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.

    • 2024-06-19
    • RCT · n = 66
    • Probiotics and antimicrobial proteins 17(5)
    • • Irini Lazou-Ahrén
      • Malin Björklund
      • Göran Molin
      • Jie Xu
      • Gunilla Önning
      • Sölve Elmståhl
      • Bengt Jeppsson

    • PubMed: 38896223
    • DOI: 10.1007/s12602-024-10310-7

    4 Insights on

    • Improved Cognitive Function
    • Reduced Inflammation
    • Reduced C-Reactive Protein Levels
    • Reduced Calprotectin Level

    • High evidence
    • Rigorous Journal

  • Evaluation of 12-Week Standardized Beetroot Extract Supplementation in Older Participants: A Preliminary Study of Human Health Safety.

    • 2024-06-19
    • RCT
    • Nutrients 16(12)
    • • Vivian Dos Santos Pinheiro
      • Olavo João Frederico Ramos Junior
      • Caroline Flach Ortmann
      • Anurag Pande
      • Carlos Adam Conte-Junior
      • Thiago Silveira Alvares

    • PubMed: 38931296
    • DOI: 10.3390/nu16121942

    2 Insights on

    • Improved Insulin Levels
    • Increased Nitrate Level

    • High evidence
    • Rigorous Journal
• June 21

  • AG1®, a Novel Synbiotic, Maintains Gut Barrier Function following Inflammatory Challenge in a Caco-2/THP1-Blue™ Co-Culture Model.

    • 2024-06-21
    • Microorganisms 12(7)
    • • Philip A Sapp
      • Jeremy R Townsend
      • Trevor O Kirby
      • Marlies Govaert
      • Cindy Duysburgh
      • Lynn Verstrepen
      • Massimo Marzorati
      • Tess M Marshall
      • Ralph Esposito

    • PubMed: 39065031
    • DOI: 10.3390/microorganisms12071263

    1 Insight on

    • Improved Gut Barrier Function

    • Low evidence
• June 24

  • Probiotics for oral health: a critical evaluation of bacterial strains.

    • 2024-06-24
    • Review
    • Frontiers in microbiology 15
    • • Rachelle E Beattie

    • PubMed: 38979537
    • DOI: 10.3389/fmicb.2024.1430810

    5 Insights on

    • Reduced Dental Caries
    • Reduced Halitosis
    • Improved Oral Health
    • Reduced Oral Pathogen Growth
    • Reduced Halitosis-Associated Bacteria

    • Low evidence
• June 25

  • Bifidobacterium lactis and Lactobacillus plantarum Enhance Immune Function and Antioxidant Capacity in Cats through Modulation of the Gut Microbiota.

    • 2024-06-25
    • Antioxidants (Basel, Switzerland) 13(7)
    • • Weiwei Wang
      • Hao Dong
      • Xiaohan Chang
      • Qianqian Chen
      • Longjiao Wang
      • Shuxing Chen
      • Lishui Chen
      • Ran Wang
      • Shaoyang Ge
      • Pengjie Wang
      • Yixuan Li
      • Siyuan Liu
      • Wei Xiong

    • PubMed: 39061833
    • DOI: 10.3390/antiox13070764

    5 Insights on

    • Improved Immune Function
    • Improved Antioxidant Capacity
    • Increased Antioxidant Capacity
    • Improved Gut Barrier Function
    • Increased Beneficial Gut Microbiota Abundance

    • Low evidence

  • Characterization of a Ligilactobacillus salivarius Strain Isolated from a Cheese Seal Which Was Last Used in 1936.

    • 2024-06-25
    • Case Report
    • Foods (Basel, Switzerland) 13(13)
    • • Claudio Alba
      • Rebeca Arroyo
      • Leónides Fernández
      • Arjan Narbad
      • Juan M Rodríguez

    • PubMed: 38998510
    • DOI: 10.3390/foods13132005

    3 Insights on

    • Improved Gastrointestinal Health
    • Improved Gut Health
    • Safety And Tolerability

    • Low evidence
• June 26

  • Efficacy of Pea Protein Supplementation in Combination with a Resistance Training Program on Muscle Performance in a Sedentary Adult Population: A Randomized, Comparator-Controlled, Parallel Clinical Trial.

    • 2024-06-26
    • RCT
    • Nutrients 16(13)
    • • Ruma G Singh
      • Laetitia Guérin-Deremaux
      • Catherine Lefranc-Millot
      • Caroline Perreau
      • David C Crowley
      • Erin D Lewis
      • Malkanthi Evans
      • Marc Moulin

    • PubMed: 38999765
    • DOI: 10.3390/nu16132017

    1 Insight on

    • Improved Muscle Strength

    • High evidence
    • Rigorous Journal

  • An exploratory study of a multi-species probiotic formulation and markers of health in a real-world oncological cohort in the time of covid.

    • 2024-06-26
    • Clinical Trial
    • Inflammopharmacology 32(4)
    • • Michael Thomsen
      • Ravichandra Vemuri
      • Flavia Huygens
      • Stephen Clarke
      • Luis Vitetta

    • PubMed: 38926298
    • DOI: 10.1007/s10787-024-01503-1

    8 Insights on

    • Reduced Inflammation
    • Unchanged Stool Consistency
    • Improved Gastrointestinal Symptoms
    • Maintained Gut Microbiota Diversity
    • Healthy Gut Microbiome
    • Improved Emotional Well-Being Quality of Life
    • Improved Emotional Well-being
    • No Increase in Plasma Endotoxin

    • Moderate evidence

  • Vitamin E for the Prevention of Contrast-Induced Nephropathy: A Systematic Review and Meta-Analysis.

    • 2024-06-26
    • Review · n = 5
    • Cureus 16(6)
    • • Ahmed Ali Awaji
      • Basel H Bakhamees
      • Nouf K Alalshaikh
      • Nawaf M Albelwi
      • Mead M Al-Zahrani
      • Khalaf F Alshammari
      • Shaden D Almutairi
      • Ilaf M Siraj
      • Taif N Aljaber
      • Raghad S Alnajdi
      • Shatha S Al-Majnooni
      • Abdulaziz S Alserhani

    • PubMed: 39070434
    • DOI: 10.7759/cureus.63256

    1 Insight on

    • Reduced Contrast-Induced Nephropathy

    • Low evidence
• June 27

  • Breed-Driven Microbiome Heterogeneity Regulates Intestinal Stem Cell Proliferation via Lactobacillus-Lactate-GPR81 Signaling.

    • 2024-06-27
    • Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11(33)
    • • Haiqin Wu
      • Chunlong Mu
      • Xuan Li
      • Wenlu Fan
      • Le Shen
      • Weiyun Zhu

    • PubMed: 38937989
    • DOI: 10.1002/advs.202400058

    3 Insights on

    • Increased Intestinal Stem Cell Proliferation
    • Enhanced Intestinal Epithelial Cell Growth
    • Activated Wnt/Beta-Catenin Signaling

    • Low evidence
    • Animal Study

  • Exploring the gut microbiome: probiotics, prebiotics, synbiotics, and postbiotics as key players in human health and disease improvement.

    • 2024-06-27
    • Review
    • Food science and biotechnology 33(9)
    • • You-Tae Kim
      • David A Mills

    • PubMed: 39130661
    • DOI: 10.1007/s10068-024-01620-1

    2 Insights on

    • Improved Gut Microbiota Composition
    • Improved Clinical Outcomes

    • Low evidence

  • Cognitive and Emotional Effect of a Multi-species Probiotic Containing Lactobacillus rhamnosus and Bifidobacterium lactis in Healthy Older Adults: A Double-Blind Randomized Placebo-Controlled Crossover Trial.

    • 2024-06-27
    • RCT
    • Probiotics and antimicrobial proteins 17(5)
    • • Cristofer Ruiz-Gonzalez
      • Diana Cardona
      • Lola Rueda-Ruzafa
      • Miguel Rodriguez-Arrastia
      • Carmen Ropero-Padilla
      • Pablo Roman

    • PubMed: 38935259
    • DOI: 10.1007/s12602-024-10315-2

    3 Insights on

    • Improved Cognitive Function
    • Reduced Depression Symptoms
    • Improved Memory Function

    • High evidence
• June 28

  • Efficacy of a yeast postbiotic on cold/flu symptoms in healthy children: A randomized-controlled trial.

    • 2024-06-28
    • RCT
    • Pediatric research 96(7)
    • • Ruma G Singh
      • Vicenta Garcia-Campayo
      • Justin B Green
      • Neil Paton
      • Julissa D Saunders
      • Huda Al-Wahsh
      • David C Crowley
      • Erin D Lewis
      • Malkanthi Evans
      • Marc Moulin

    • PubMed: 38942887
    • DOI: 10.1038/s41390-024-03331-z

    2 Insights on

    • Reduced Cold/Flu Severity
    • Reduced Cold/Flu Medication Use

    • High evidence
• June 30

  • Gamma-aminobutyric acid for delaying type 1 diabetes mellitus: an update.

    • 2024-06-30
    • Review
    • Annals of pediatric endocrinology & metabolism 29(3)
    • • Jane Carissa Sutedja
      • Bryan Gervais de Liyis
      • Made Ratna Saraswati

    • PubMed: 38956751
    • DOI: 10.6065/apem.2346184.092

    1 Insight on

    • Delayed Onset of Type 1 Diabetes Mellitus

    • Low evidence
• Undated – 3 supplement studies

  • Effects of Lactobacillus plantarum supplementation on glucose and lipid metabolism in type 2 diabetes mellitus and prediabetes: A systematic review and meta-analysis of randomized controlled trials.

    • 2024-06
    • Meta-Analysis · n = 5
    • Clinical nutrition ESPEN 61
    • • Hao Zhong
      • Lingmiao Wang
      • Fuhuai Jia
      • Yongqiu Yan
      • Feifei Xiong
      • Yunhong Li
      • Khemayanto Hidayat
      • Rongfa Guan

    • PubMed: 38777458
    • DOI: 10.1016/j.clnesp.2024.04.009

    10 Insights on

    • Improved Insulin Sensitivity
    • Reduced Low-Density Lipoprotein Level
    • Reduced Triglyceride Levels
    • Increased HDL Cholesterol Levels
    • Reduced LDL Cholesterol
    • Reduced Hemoglobin A1c
    • Improved Insulin Resistance
    • Improved Fasting Plasma Glucose
    • Reduced Total Cholesterol
    • Increased High-Density Lipoprotein Cholesterol

    • High evidence

  • Use of probiotics in preventing and treating excess weight and obesity. A systematic review.

    • 2024-06
    • Systematic Review
    • Obesity science & practice 10(3)
    • • Belén Torres
      • María C Sánchez
      • Leire Virto
      • Arancha Llama-Palacios
      • María J Ciudad
      • Luis Collado

    • PubMed: 38903852
    • DOI: 10.1002/osp4.759

    4 Insights on

    • Reduced Waist Circumference
    • Reduced Body Mass Index
    • Reduced Body Weight
    • Reduced Body Fat Mass

    • High evidence

  • Urinary metabolome of infants with colic treated with Lactobacillus reuteri DSM 17938: a pilot randomized trial.

    • 2024-06
    • RCT
    • Minerva pediatrics 76(3)
    • • Francesco Savino
      • Vassilios Fanos
      • Antonio Noto
      • Deborah Biggio
      • Claudia Fattuoni
      • Luigi Barberini

    • PubMed: 33438855
    • DOI: 10.23736/s2724-5276.20.06128-9

    2 Insights on

    • Altered Metabolite Profile
    • Increased Urinary Abundance of Nutrient-Related Metabolites

    • High evidence