May 2023 Supplement Research Papers

• May 1

  • Association of serum homocysteine, folate, and vitamin B12 and mood following the Swank and Wahls elimination dietary interventions in relapsing-remitting multiple sclerosis: Secondary analysis of the WAVES trial.

    • 2023-05-01
    • RCT · n = 77
    • Multiple sclerosis and related disorders 75
    • • Farnoosh Shemirani
      • Tyler J Titcomb
      • Solange M Saxby
      • Patrick Ten Eyck
      • Linda M Rubenstein
      • Karin F Hoth
      • Linda G Snetselaar
      • Terry L Wahls

    • PubMed: 37148578
    • DOI: 10.1016/j.msard.2023.104743

    3 Insights on

    • Reduced Anxiety
    • Reduced Depression Symptoms
    • Improved Mental Health Inventory Score

    • High evidence
• May 2

  • The effects of melissa officinalis on depression and anxiety in type 2 diabetes patients with depression: a randomized double-blinded placebo-controlled clinical trial.

    • 2023-05-02
    • RCT · n = 44
    • BMC complementary medicine and therapies 23(1)
    • • Mostafa Safari
      • Akbar Asadi
      • Naheed Aryaeian
      • Hasan Fallah Huseini
      • Farzad Shidfar
      • Shima Jazayeri
      • Mojtaba Malek
      • Agha Fateme Hosseini
      • Zahra Hamidi

    • PubMed: 37131158
    • DOI: 10.1186/s12906-023-03978-x

    8 Insights on

    • Reduced Anxiety
    • Reduced Body Weight
    • Reduced Systolic Blood Pressure
    • Reduced C-Reactive Protein Levels
    • Reduced Depression Symptoms
    • Reduced Diastolic Blood Pressure
    • Improved Sleep Quality
    • Reduced Fasting Blood Glucose Levels

    • High evidence
• May 4

  • Influence of Bifidobacterium breve on the Glycaemic Control, Lipid Profile and Microbiome of Type 2 Diabetic Subjects: A Preliminary Randomized Clinical Trial.

    • 2023-05-04
    • RCT
    • Pharmaceuticals (Basel, Switzerland) 16(5)
    • • Chaiyavat Chaiyasut
      • Bhagavathi Sundaram Sivamaruthi
      • Narissara Lailerd
      • Sasithorn Sirilun
      • Subramanian Thangaleela
      • Suchanat Khongtan
      • Muruganantham Bharathi
      • Periyanaina Kesika
      • Manee Saelee
      • Thiwanya Choeisoongnern
      • Pranom Fukngoen
      • Sartjin Peerajan
      • Phakkharawat Sittiprapaporn

    • PubMed: 37242478
    • DOI: 10.3390/ph16050695

    9 Insights on

    • Reduced HbA1c Level
    • Improved Kidney Function
    • Reduced LDL Cholesterol
    • Reduced Triglyceride Levels
    • Reduced Creatinine Level
    • Improved Glycemia
    • Reduced Blood Urea Nitrogen Levels
    • Improved Blood Lipid Profile
    • Reduced Fasting Blood Glucose Levels

    • High evidence
• May 5

  • Analysis of the microbial content of probiotic products commercialized worldwide and survivability in conditions mimicking the human gut environment.

    • 2023-05-05
    • Frontiers in microbiology 14
    • • Emilia Ghelardi
      • Diletta Mazzantini
      • Francesco Celandroni
      • Marco Calvigioni
      • Adelaide Panattoni
      • Antonella Lupetti
      • Beatrice Bois De Fer
      • Marcos Perez

    • PubMed: 37234535
    • DOI: 10.3389/fmicb.2023.1127321

    1 Insight on

    • No Human Health Outcome Reported

    • Low evidence

  • The effect of probiotic supplementation on episiotomy wound healing among primiparous women: a triple-blind randomized clinical trial.

    • 2023-05-05
    • RCT
    • BMC complementary medicine and therapies 23(1)
    • • Derakhshan Abdollahpour
      • Aziz Homayouni-Rad
      • Roghaiyeh Nourizadeh
      • Sevil Hakimi
      • Esmat Mehrabi

    • PubMed: 37147630
    • DOI: 10.1186/s12906-023-03980-3

    2 Insights on

    • Reduced Pain
    • Improved Wound Healing

    • High evidence

  • Changes in the Gut Microbiota after the Use of Herbal Medicines in Overweight and Obese Individuals: A Systematic Review.

    • 2023-05-05
    • Systematic Review
    • Nutrients 15(9)
    • • Miguel Huang
      • Cláudia Dos Santos Cople-Rodrigues
      • Dan L Waitzberg
      • Ilanna Marques Gomes da Rocha
      • Cintia Chaves Curioni

    • PubMed: 37432344
    • DOI: 10.3390/nu15092203

    1 Insight on

    • Reduced Body Weight

    • High evidence
    • Rigorous Journal
• May 8

  • Positive Effects of Probiotic Therapy in Patients with Post-Infectious Fatigue.

    • 2023-05-08
    • RCT · n = 70
    • Metabolites 13(5)
    • • Katharina Obermoser
      • Natascha Brigo
      • Andrea Schroll
      • Pablo Monfort-Lanzas
      • Johanna M Gostner
      • Sabine Engl
      • Simon Geisler
      • Miriam Knoll
      • Harald Schennach
      • Günter Weiss
      • Dietmar Fuchs
      • Rosa Bellmann-Weiler
      • Katharina Kurz

    • PubMed: 37233680
    • DOI: 10.3390/metabo13050639

    4 Insights on

    • Improved Quality of Life
    • Reduced Neopterin Levels
    • Reduced Fatigue
    • Improved Depressive Symptoms

    • High evidence

  • Efficacy and safety of bromelain: A systematic review and meta-analysis.

    • 2023-05-08
    • Meta-Analysis
    • Nutrition and health 29(3)
    • • Nattawut Leelakanok
      • Arpa Petchsomrit
      • Thitapa Janurai
      • Charinrat Saechan
      • Niti Sunsandee

    • PubMed: 37157782
    • DOI: 10.1177/02601060231173732

    11 Insights on

    • Increased Pain
    • Increased Sepsis
    • Improved Cardiovascular Disease Marker
    • Increased Burning Sensation
    • Reduced Debridement Time
    • Reduced Sinusitis Severity
    • Increased Nausea
    • Increased Fever
    • Increased Headache
    • Reduced Flatulence
    • Reduced Pain

    • High evidence

  • Bifidobacterium breve CBT BR3 is effective at relieving intestinal inflammation by augmenting goblet cell regeneration

    • 2023-05-08
    • Journal of Gastroenterology and Hepatology 38(8)
    • • I. Park
      • Ji Hyung Kim
      • Jongwook Yu
      • Yoojin Shin
      • K. Kim
      • T. Kim
      • S. Kim
      • J. Cheon

    • PubMed: 37157108
    • DOI: 10.1111/jgh.16209

    4 Insights on

    • Improved Epithelial Permeability
    • Enhanced Goblet Cell Regeneration
    • Reduced Intestinal Inflammation
    • Enhanced Goblet Cell Function

    • Low evidence
• May 9

  • A Review of l-Methylfolate as Adjunctive Therapy in the Treatment of Major Depressive Disorder.

    • 2023-05-09
    • Review
    • The primary care companion for CNS disorders 25(3)
    • • Vladimir Maletic
      • Richard Shelton
      • Valerie Holmes

    • PubMed: 37192264
    • DOI: 10.4088/pcc.22nr03361

    2 Insights on

    • Reduced Inflammatory Markers
    • Improved Depressive Symptoms

    • Low evidence
• May 10

  • A systematic review of the protective effects of silymarin/silibinin against doxorubicin-induced cardiotoxicity.

    • 2023-05-10
    • Review
    • Cancer cell international 23(1)
    • • Mandeep Singh
      • Mustafa M Kadhim
      • Abduladheem Turki Jalil
      • Shamam Kareem Oudah
      • Zafar Aminov
      • Fahad Alsaikhan
      • Zanko Hassan Jawhar
      • Andrés Alexis Ramírez-Coronel
      • Bagher Farhood

    • PubMed: 37165384
    • DOI: 10.1186/s12935-023-02936-4

    8 Insights on

    • Improved Systolic Myocardial Velocity
    • Reduced QRS Interval
    • Reduced QT Interval
    • Improved Heart Rate
    • Improved Fractional Shortening
    • Improved Ejection Fraction
    • Improved Cardiac Histopathology
    • Reduced Cardiac Biochemical Marker

    • Low evidence

  • Potential Modulation of Inflammation and Physical Function by Combined Probiotics, Omega-3 Supplementation and Vitamin D Supplementation in Overweight/Obese Patients with Chronic Low-Grade Inflammation: A Randomized, Placebo-Controlled Trial.

    • 2023-05-10
    • RCT · n = 76
    • International journal of molecular sciences 24(10)
    • • Lena Kopp
      • Anna Schweinlin
      • Lina Tingö
      • Ashley N Hutchinson
      • Viktoria Feit
      • Tabea Jähnichen
      • Katja Lehnert
      • Walter Vetter
      • Andreas Rings
      • Morten G Jensen
      • Robert J Brummer
      • Stephan C Bischoff

    • PubMed: 37239916
    • DOI: 10.3390/ijms24108567

    5 Insights on

    • Improved Physical Function
    • Reduced Omega-6 to Omega-3 Ratio
    • Reduced Arachidonic Acid/Eicosapentaenoic Acid Ratio
    • Reduced High-Sensitivity C-Reactive Protein Level
    • Reduced Interleukin-6 Levels

    • High evidence
    • Rigorous Journal

  • Psyllium is a natural nonfermented gel-forming fiber that is effective for weight loss: A comprehensive review and meta-analysis.

    • 2023-05-10
    • Meta-Analysis · n = 354
    • Journal of the American Association of Nurse Practitioners 35(8)
    • • Roger D Gibb
      • Kyle J Sloan
      • Johnson W McRorie

    • PubMed: 37163454
    • DOI: 10.1097/jxx.0000000000000882

    3 Insights on

    • Reduced Body Weight
    • Reduced Body Mass Index
    • Reduced Waist Circumference

    • High evidence

  • Dietary Supplementation of Lactobacillus johnsonii RS-7 Improved Antioxidant and Immune Function of Weaned Piglets

    • 2023-05-10
    • RCT
    • Animals 13(10)
    • • Kai Zhao
      • H. Yin
      • H. Yan
      • Wenjie Tang
      • H. Diao
      • Qi Wang
      • R. Qi
      • Jingbo Liu

    • PubMed: 37238025
    • DOI: 10.3390/ani13101595

    2 Insights on

    • Elevated Antioxidant Levels
    • Increased Immunoglobulin Levels

    • High evidence

  • Lactobacillus brevis alleviates the progress of hepatocellular carcinoma and type 2 diabetes in mice model via interplay of gut microflora, bile acid and NOTCH 1 signaling

    • 2023-05-10
    • Clinical Trial
    • Frontiers in Immunology 14
    • • Shujia Chen
      • P. Han
      • Qian Zhang
      • Peiyan Liu
      • Jie Liu
      • Lili Zhao
      • Lianyi Guo
      • Jia Li

    • PubMed: 37234174
    • DOI: 10.3389/fimmu.2023.1179014

    8 Insights on

    • Improved Blood Glucose Levels
    • Delayed Disease Progression
    • Improved Gut Microflora
    • Modulated Intestinal Microflora Composition
    • Reduced Hepatocellular Carcinoma Progression
    • Reduced Incidence of Colon Cancer
    • Improved Prognosis of Type 2 Diabetes Mellitus
    • Improved Insulin Sensitivity

    • Low evidence
    • Animal Study
• May 12

  • Red Yeast Rice for the Improvement of Lipid Profiles in Mild-to-Moderate Hypercholesterolemia: A Narrative Review.

    • 2023-05-12
    • Review
    • Nutrients 15(10)
    • • Arrigo F G Cicero
      • Federica Fogacci
      • Anca Pantea Stoian
      • Peter P Toth

    • PubMed: 37242171
    • DOI: 10.3390/nu15102288

    2 Insights on

    • Reduced Atherosclerotic Cardiovascular Disease Event
    • Reduced Low-Density Lipoprotein Level

    • Moderate evidence
    • Rigorous Journal

  • Vitamin K supplementation and vascular calcification: a systematic review and meta-analysis of randomized controlled trials.

    • 2023-05-12
    • Systematic Review · n = 533
    • Frontiers in nutrition 10
    • • Te Li
      • Yun Wang
      • Wei-Ping Tu

    • PubMed: 37252246
    • DOI: 10.3389/fnut.2023.1115069

    2 Insights on

    • Reduced Dephosphorylated-Uncarboxylated Matrix Gla Protein Level
    • Reduced Coronary Artery Calcification

    • High evidence

  • Randomized Clinical Trial of Oral Probiotic Streptococcus salivarius M18 on Salivary Streptococcus mutans in Preprimary Children.

    • 2023-05-12
    • RCT · n = 40
    • International journal of clinical pediatric dentistry 16(2)
    • • Henna Palampadiyan Salim
      • Shanthala B Mallikarjun
      • Shashidara Raju
      • Austin R Surendranath

    • PubMed: 37519958
    • DOI: 10.5005/jp-journals-10005-2527

    2 Insights on

    • Improved Salivary Buffering Capacity
    • Reduced Salivary Levels of Mutans Streptococci

    • High evidence
• May 13

  • The effect of bromelain in periodontal surgery: a double-blind randomized placebo-controlled trial.

    • 2023-05-13
    • RCT
    • BMC oral health 23(1)
    • • Hossein Babazade
      • Arad Mirzaagha
      • Shokoofeh Konarizadeh

    • PubMed: 37179311
    • DOI: 10.1186/s12903-023-02971-7

    4 Insights on

    • Reduced Bleeding on Probing (BOP)
    • Reduced Gingival Index
    • Reduced Plaque Index
    • Reduced Probing Pocket Depth

    • High evidence
• May 16

  • Effects of Probiotics and Vitamin D3 Supplementation on Sports Performance Markers in Male Mixed Martial Arts Athletes: A Randomized Trial.

    • 2023-05-16
    • RCT · n = 12
    • Sports medicine - open 9(1)
    • • Katarzyna Przewłócka
      • Sylwester Kujach
      • Piotr Sawicki
      • Paweł Berezka
      • Zofia Kinga Bytowska
      • Marcin Folwarski
      • Kondrat Kowalski
      • Jan Jacek Kaczor

    • PubMed: 37193828
    • DOI: 10.1186/s40798-023-00576-6

    5 Insights on

    • Improved Lactate Clearance
    • Improved Lactate Utilization
    • Improved Athletic Performance
    • Increased Total Work
    • Increased Mean Anaerobic Power

    • High evidence

  • Antiobesity effects of onion (Allium cepa) in subjects with obesity: Systematic review and meta-analysis.

    • 2023-05-16
    • Review · n = 38
    • Food science & nutrition 11(8)
    • • Min-Yu Chung
      • Jin-Taek Hwang
      • Soo-Hyun Park

    • PubMed: 37576046
    • DOI: 10.1002/fsn3.3426

    4 Insights on

    • Reduced Body Weight
    • Reduced Body Mass Index
    • Reduced Triglyceride Levels
    • Reduced Waist Circumference

    • Moderate evidence
• May 18

  • Effect of Inhibiting Butyrylcholinesterase Activity Using Fractionated Coffee Extracts Digested In Vitro in Gastrointestinal Tract: Docking Simulation and Calorimetric and Studies.

    • 2023-05-18
    • Nutrients 15(10)
    • • Joanna Grzelczyk
      • Dominik Szwajgier
      • Ewa Baranowska-Wójcik
      • Horacio Pérez-Sánchez
      • Miguel Carmena-Bargueño
      • Bożena Sosnowska
      • Grażyna Budryn

    • PubMed: 37242249
    • DOI: 10.3390/nu15102366

    1 Insight on

    • Reduced Butyrylcholinesterase Activity

    • Low evidence
    • Rigorous Journal
• May 19

  • Fermented Beverage Benefits: A Comprehensive Review and Comparison of Kombucha and Kefir Microbiome.

    • 2023-05-19
    • Review
    • Microorganisms 11(5)
    • • Ann Qi Chong
      • Siew Wen Lau
      • Nyuk Ling Chin
      • Rosnita A Talib
      • Roseliza Kadir Basha

    • PubMed: 37317318
    • DOI: 10.3390/microorganisms11051344

    1 Insight on

    • Improved Gastrointestinal Health

    • Low evidence

  • Probiotic modulation of gut microbiota by Bacillus coagulans MTCC 5856 in healthy subjects: A randomized, double-blind, placebo-control study

    • 2023-05-19
    • RCT · n = 30
    • Medicine 102(20)
    • • M. Majeed
      • K. Nagabhushanam
      • Lakshmi A Mundkur
      • Shaji Paulose
      • H. Divakar
      • Sudha Rao
      • S. Arumugam

    • PubMed: 37335737
    • DOI: 10.1097/MD.0000000000033751

    12 Insights on

    • Improved Abundance of Beneficial Bacteria
    • Improved Blood Biochemical Parameter
    • Absence of Adverse Events
    • Increased Beneficial Bacterial Species
    • Improved General Health
    • Improved Stability of Gut Microbiota
    • Safety of Consumption
    • Maintained Gut Microbiome Composition
    • Increased Beneficial Gut Bacteria
    • Safety for Consumption
    • Balanced Gut Microbiome
    • Improved Gut Health

    • High evidence
• May 22

  • [Integrative medicine, naturopathic and complementary medicine in the treatment of fibromyalgia syndrome : An overview against the background of clinical experiences from routine treatment].

    • 2023-05-22
    • Review
    • Schmerz (Berlin, Germany) 37(5)
    • • Andrea Langhorst
      • Jost Langhorst

    • PubMed: 37217810
    • DOI: 10.1007/s00482-023-00716-7

    2 Insights on

    • Reduced Pain
    • Improved Sleep

    • Low evidence
• May 23

  • Effect of milk protein and whey permeate in large quantity lipid-based nutrient supplement on linear growth and body composition among stunted children: A randomized 2 × 2 factorial trial in Uganda.

    • 2023-05-23
    • RCT · n = 750
    • PLoS medicine 20(5)
    • • Joseph Mbabazi
      • Hannah Pesu
      • Rolland Mutumba
      • Suzanne Filteau
      • Jack I Lewis
      • Jonathan C Wells
      • Mette F Olsen
      • André Briend
      • Kim F Michaelsen
      • Christian Mølgaard
      • Christian Ritz
      • Nicolette Nabukeera-Barungi
      • Ezekiel Mupere
      • Henrik Friis
      • Benedikte Grenov

    • PubMed: 37220111
    • DOI: 10.1371/journal.pmed.1004227

    2 Insights on

    • Increased Height
    • Increased Knee-Heel Length

    • High evidence
    • Large Human Trial
    • Rigorous Journal

  • How effective are anthocyanins on healthy modification of cardiometabolic risk factors: a systematic review and meta-analysis.

    • 2023-05-23
    • Review
    • Diabetology & metabolic syndrome 15(1)
    • • Tirang R Neyestani
      • Zahra Yari
      • Hamid Rasekhi
      • Bahareh Nikooyeh

    • PubMed: 37221605
    • DOI: 10.1186/s13098-023-01075-0

    10 Insights on

    • Reduced Blood Cholesterol
    • Reduced Body Mass Index
    • Reduced LDL Cholesterol
    • Reduced Triglyceride Levels
    • Reduced Hemoglobin A1c
    • Reduced Apolipoprotein B Levels
    • Reduced Fasting Blood Glucose Levels
    • Reduced Body Fat Mass
    • Increased High-Density Lipoprotein Cholesterol
    • Increased Apolipoprotein E Levels

    • Low evidence
• May 24

  • Chemoprevention in oral leukoplakia: challenges and current landscape.

    • 2023-05-24
    • Review
    • Frontiers in oral health 4
    • • Victor de Mello Palma
      • Natalia Koerich Laureano
      • Luiza Abrahão Frank
      • Pantelis Varvaki Rados
      • Fernanda Visioli

    • PubMed: 37293562
    • DOI: 10.3389/froh.2023.1191347

    1 Insight on

    • Reduced Oral Leukoplakia Progression

    • Low evidence

  • Dioscorea esculenta Intake with Resistance Training Improves Muscle Quantity and Quality in Healthy Middle-Aged and Older Adults: A Randomized Controlled Trial.

    • 2023-05-24
    • RCT · n = 66
    • Nutrients 15(11)
    • • Keiko Iemitsu
      • Shumpei Fujie
      • Masataka Uchida
      • Kenichiro Inoue
      • Yasushi Shinohara
      • Motoyuki Iemitsu

    • PubMed: 37299401
    • DOI: 10.3390/nu15112438

    4 Insights on

    • Improved Muscle Thickness
    • Improved Muscle Quality
    • Reduced Complement Component 1q Level
    • Improved Five Times Sit-to-Stand Time

    • High evidence
    • Rigorous Journal
• May 26

  • Effects of cold storage time on the quality and active probiotics of yogurt fermented by Bifidobacterium lactis and commercial bacteria Danisco.

    • 2023-05-26
    • Journal of food science 88(7)
    • • Xinyue Xu
      • Huaitian Cui
      • Jiaxin Xu
      • Zhiheng Yuan
      • Jun Li
      • Lina Yang
      • Shengnan Wang
      • He Liu
      • Danshi Zhu

    • PubMed: 37243357
    • DOI: 10.1111/1750-3841.16601

    1 Insight on

    • Reduced Nutrient Content

    • Low evidence
• May 27

  • The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.

    • 2023-05-27
    • Meta-Analysis · n = 787
    • Neurogastroenterology and motility 35(11)
    • • Alice van der Schoot
      • Alice Creedon
      • Kevin Whelan
      • Eirini Dimidi

    • PubMed: 37243443
    • DOI: 10.1111/nmo.14613

    1 Insight on

    • Increased Treatment Response

    • High evidence

  • L-theanine combination therapy with fluvoxamine in moderate-to-severe obsessive-compulsive disorder: A placebo-controlled, double-blind, randomized trial.

    • 2023-05-27
    • RCT · n = 95
    • Psychiatry and clinical neurosciences 77(9)
    • • Mehran Nematizadeh
      • Hossein Ghorbanzadeh
      • Hossein Sanjari Moghaddam
      • Mohammadreza Shalbafan
      • Mahsa Boroon
      • Amir-Abbas Keshavarz-Akhlaghi
      • Shahin Akhondzadeh

    • PubMed: 37169515
    • DOI: 10.1111/pcn.13565

    4 Insights on

    • Reduced Obsessive Symptom
    • Reduced Obsessive-Compulsive Symptoms
    • Reduced Compulsive Symptoms
    • Improved Response Rate

    • High evidence

  • Does whey protein supplementation during resistance exercise have additional benefits for decreasing hepatic fat content?

    • 2023-05-27
    • RCT · n = 34
    • Journal of the International Society of Sports Nutrition 20(1)
    • • Chae-Been Kim
      • Hyoung-Su Park
      • Hye-Jin Kim
      • Hong-Soo Kim
      • Jung-Jun Park

    • PubMed: 37245070
    • DOI: 10.1080/15502783.2023.2217783

    5 Insights on

    • Reduced Alanine Aminotransferase Level
    • Reduced Blood Cholesterol
    • Reduced Low-Density Lipoprotein Level
    • Reduced Hepatic Fat Content
    • Reduced Aspartate Transaminase Level

    • High evidence
• May 30

  • Influence of the Probiotic L. reuteri on Periodontal Clinical Parameters after Nonsurgical Treatment: A Systematic Review.

    • 2023-05-30
    • Review
    • Microorganisms 11(6)
    • • Carlota Ochôa
      • Filipe Castro
      • José Frias Bulhosa
      • Conceição Manso
      • Juliana Campos Hasse Fernandes
      • Gustavo Vicentis Oliveira Fernandes

    • PubMed: 37374951
    • DOI: 10.3390/microorganisms11061449

    1 Insight on

    • Improved Periodontal Clinical Parameters

    • Low evidence

  • The Anabolic Effect of Fenugreek: A Systematic Review with Meta-analysis.

    • 2023-05-30
    • Meta-Analysis · n = 449
    • International journal of sports medicine 44(10)
    • • Eduard Isenmann
      • Pijus Alisauskas
      • Ulrich Flenker
      • Jan Schalla
      • Patrick Diel

    • PubMed: 37253363
    • DOI: 10.1055/a-2048-5925

    5 Insights on

    • Improved Leg Press Performance
    • Increased Lean Body Mass
    • Reduced Body Fat Mass
    • Increased Total Testosterone
    • Increased Testosterone Level

    • High evidence

  • Bacillus coagulans GBI-30, 6086 (BC30) improves lactose digestion in rats exposed to a high-lactose meal.

    • 2023-05-30
    • n = 10
    • European journal of nutrition 62(6)
    • • Joan Teichenné
      • Úrsula Catalán
      • Roger Mariné-Casadó
      • Cristina Domenech-Coca
      • Anna Mas-Capdevila
      • Juan María Alcaide-Hidalgo
      • Gertruda Chomiciute
      • Ana Rodríguez-García
      • Ana Hernández
      • Vanessa Gutierrez
      • Francesc Puiggròs
      • Josep M Del Bas
      • Antoni Caimari

    • PubMed: 37249602
    • DOI: 10.1007/s00394-023-03183-z

    3 Insights on

    • Improved Lactose-Associated Malnutrition
    • Improved Small Intestine Length
    • Improved Lactose Digestion

    • Low evidence
    • Rigorous Journal
    • Animal Study
• May 31

  • L-Arginine supplementation in pregnancy: a systematic review of maternal and fetal outcomes.

    • 2023-05-31
    • Systematic Review
    • The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 36(1)
    • • Daniela Menichini
      • Lia Feliciello
      • Isabella Neri
      • Fabio Facchinetti

    • PubMed: 37258415
    • DOI: 10.1080/14767058.2023.2217465

    7 Insights on

    • Reduced Pre-Eclampsia Development
    • Reduced Need for Antihypertensive Drug
    • Reduced Blood Pressure
    • Improved Neonatal Health Outcomes
    • Improved Fetoplacental Circulation
    • Improved Birth Weight
    • Reduced Uterine Contraction

    • High evidence

  • Effects of Bacterial Lysates and Metabolites on Collagen Homeostasis in TNF-α-Challenged Human Dermal Fibroblasts.

    • 2023-05-31
    • Microorganisms 11(6)
    • • Laura Huuskonen
      • Heli Anglenius
      • Ilmari Ahonen
      • Kirsti Tiihonen

    • PubMed: 37374969
    • DOI: 10.3390/microorganisms11061465

    2 Insights on

    • Reduced Pro-inflammatory Cytokine Levels
    • Improved Collagen Homeostasis

    • Low evidence

  • Effects of an Extract of the Brown Seaweed Ascophylum nodosum on Postprandial Glycaemic Control in Healthy Subjects: A Randomized Controlled Study.

    • 2023-05-31
    • RCT · n = 10
    • Marine drugs 21(6)
    • • Aleksandra Konic Ristic
      • Sinead Ryan
      • Maha Attjioui
      • Shane O'Connell
      • Eileen R Gibney

    • PubMed: 37367662
    • DOI: 10.3390/md21060337

    1 Insight on

    • Reduced Postprandial Glucose

    • High evidence
• Undated – 4 supplement studies

  • Bovine colostrum as a fortifier to human milk in very preterm infants - A randomized controlled trial (FortiColos).

    • 2023-05
    • RCT · n = 232
    • Clinical nutrition (Edinburgh, Scotland) 42(5)
    • • Agnethe May Ahnfeldt
      • Lise Aunsholt
      • Bo Moelholm Hansen
      • Bente Hoest
      • Valdís Jóhannsdóttir
      • Susanne Soendergaard Kappel
      • Anja Klamer
      • Sören Möller
      • Bertha Kanijo Moeller
      • Per Torp Sangild
      • Ann Lawaetz Skovgaard
      • Gerrit van Hall
      • Louise Dyrberg Vibede
      • Gitte Zachariassen

    • PubMed: 37004355
    • DOI: 10.1016/j.clnu.2023.03.008

    6 Insights on

    • Increased Weight
    • Reduced Necrotising Enterocolitis
    • Increased Amino Acid Level
    • Increased Head Circumference
    • Increased Length
    • Reduced Late-Onset Sepsis

    • High evidence
    • Large Human Trial

  • Impact of Saccharomyces boulardii on jaundice in premature infants undergoing phototherapy.

    • 2023-05
    • RCT · n = 55
    • Jornal de pediatria 99(3)
    • • Di Hu
      • Ying Wang
      • Suyan Yang
      • Huijuan Zhang

    • PubMed: 36574954
    • DOI: 10.1016/j.jped.2022.10.010

    6 Insights on

    • Improved Bowel Movement Frequency
    • Reduced Phototherapy Duration
    • Reduced Jaundice Resolution Duration
    • Improved Stool Consistency
    • Reduced Total Bilirubin Level
    • Reduced Bilirubin Levels

    • High evidence

  • Effects of Kefir Consumption on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

    • 2023-05
    • Meta-Analysis · n = 314
    • Current drug targets 24(7)
    • • Farveh Yahyapoor
      • Neda Haghighat
      • Zahra Sohrabi
      • Omid Asbaghi
      • Mohammad Bagherniya
      • Tannaz Jamialahmadi
      • Amirhossein Sahebkar

    • PubMed: 37102491
    • DOI: 10.2174/1389450124666230427095742

    9 Insights on

    • Reduced Insulin Levels
    • Reduced Body Weight
    • Reduced Blood Cholesterol
    • Reduced HOMA-IR
    • Reduced LDL Cholesterol
    • Reduced Triglyceride Levels
    • Increased HDL Cholesterol Levels
    • Reduced Hemoglobin A1c
    • Reduced Fasting Blood Glucose Levels

    • High evidence

  • Effects of dietary supplementation of Pediococcus pentosaceus strains from kimchi in weaned piglet challenged with Escherichia coli and Salmonella enterica

    • 2023-05
    • RCT
    • Journal of Animal Science and Technology 65(3)
    • • D. Song
      • Jihwan Lee
      • Kangheun Kim
      • H. Oh
      • J. An
      • Seyeon Chang
      • Hyunah Cho
      • Seh-Young Park
      • K. Jeon
      • Y. Yoon
      • Yoonjeong Yoo
      • Y. Cho
      • Ji-Hun Cho

    • PubMed: 37332280
    • DOI: 10.5187/jast.2023.e31

    4 Insights on

    • Reduced Diarrhea Incidence
    • Reduced Intestinal Pathogen Bacterial Count
    • Improved Growth Performance
    • Reduced Fecal Odor

    • Low evidence
    • Animal Study