March 2024 Supplement Research Papers

• March 3

  • Evaluating the effects of Bacopa monnieri on cognitive performance and sleep quality of patients with mild cognitive impairment: A triple-blinded, randomized, placebo-controlled trial.

    • 2024-03-03
    • RCT · n = 62
    • Explore (New York, N.Y.) 20(5)
    • • Maryam Delfan
      • Parastou Kordestani-Moghaddam
      • Mohammad Gholami
      • Khadije Kazemi
      • Rasool Mohammadi

    • PubMed: 38538390
    • DOI: 10.1016/j.explore.2024.02.008

    4 Insights on

    • Improved Cognitive Function
    • Improved Attention Span
    • Improved Sleep Quality
    • Improved Verbal Fluency

    • High evidence
• March 4

  • Analysis of Bifidobacterium animalis subsp. lactis BB-12 ® and Lactobacillus rhamnosus GG on underweight and malabsorption in premature infants.

    • 2024-03-04
    • Observational
    • Revista da Associacao Medica Brasileira (1992) 70(2)
    • • Meng Xing
      • Xuran Li
      • Yinzhu Zhang

    • PubMed: 38422245
    • DOI: 10.1590/1806-9282.20230636

    6 Insights on

    • Improved Weight Gain
    • Improved Enteral Nutrition
    • Reduced Time to Full Enteral Feeding
    • Increased Weight
    • Reduced Time to Regain Birthweight
    • Reduced Time to Enteral Nutrition Transition

    • Low evidence
• March 5

  • Colonic in vitro fermentation of mycoprotein promotes shifts in gut microbiota, with enrichment of Bacteroides species.

    • 2024-03-05
    • Communications biology 7(1)
    • • Raffaele Colosimo
      • Hannah C Harris
      • Jennifer Ahn-Jarvis
      • Perla Troncoso-Rey
      • Tim J A Finnigan
      • Pete J Wilde
      • Frederick J Warren

    • PubMed: 38443511
    • DOI: 10.1038/s42003-024-05893-4

    1 Insight on

    • Increased Short-Chain Fatty Acid Production

    • Low evidence
    • Animal Study
• March 6

  • The effects of L-carnitine supplementation on inflammation, oxidative stress, and clinical outcomes in critically Ill patients with sepsis: a randomized, double-blind, controlled trial.

    • 2024-03-06
    • RCT · n = 60
    • Nutrition journal 23(1)
    • • Mahdi Keshani
      • Babak Alikiaii
      • Zahra Babaei
      • Gholamreza Askari
      • Zahra Heidari
      • Manoj Sharma
      • Mohammad Bagherniya

    • PubMed: 38444016
    • DOI: 10.1186/s12937-024-00934-4

    9 Insights on

    • Increased Serum Albumin Levels
    • Increased Antioxidant Enzyme Levels
    • Reduced Mortality Rate
    • Reduced C-Reactive Protein Levels
    • Increased Platelet Count
    • Increased Total Serum Antioxidant Capacity
    • Reduced Erythrocyte Sedimentation Rate
    • Reduced Malondialdehyde
    • Reduced Chloride Level

    • High evidence
• March 7

  • Effect of Aromatic Herbs and Spices Present in the Mediterranean Diet on the Glycemic Profile in Type 2 Diabetes Subjects: A Systematic Review and Meta-Analysis.

    • 2024-03-07
    • Meta-Analysis
    • Nutrients 16(6)
    • • María Carmen Garza
      • Sofía Pérez-Calahorra
      • Carmen Rodrigo-Carbó
      • María Antonia Sánchez-Calavera
      • Estíbaliz Jarauta
      • Rocío Mateo-Gallego
      • Irene Gracia-Rubio
      • Itziar Lamiquiz-Moneo

    • PubMed: 38542668
    • DOI: 10.3390/nu16060756

    3 Insights on

    • Improved Insulin Levels
    • Reduced Hemoglobin A1c
    • Reduced Fasting Blood Glucose Levels

    • High evidence
    • Rigorous Journal

  • Viability of Lactobacillus reuteri DSM 17938 Encapsulated by Ionic Gelation during Refractance Window® Drying of a Strawberry Snack.

    • 2024-03-07
    • Foods (Basel, Switzerland) 13(6)
    • • Esmeralda Mosquera-Vivas
      • Alfredo Ayala-Aponte
      • Liliana Serna-Cock
      • Cristian Torres-León
      • Diego F Tirado

    • PubMed: 38540812
    • DOI: 10.3390/foods13060823

    1 Insight on

    • Produced Probiotic-Enriched Functional Snack

    • Low evidence
• March 9

  • Prebiotics and Probiotics for Gastrointestinal Disorders.

    • 2024-03-09
    • Review
    • Nutrients 16(6)
    • • Sameeha Rau
      • Andrew Gregg
      • Shelby Yaceczko
      • Berkeley Limketkai

    • PubMed: 38542689
    • DOI: 10.3390/nu16060778

    1 Insight on

    • Reduced Antibiotic-Associated Diarrhea

    • Moderate evidence
    • Rigorous Journal
• March 11

  • Adjudicative efficacy of Bifidobacterium animalis subsp. lactis BLa80 in treating acute diarrhea in children: a randomized, double-blinded, placebo-controlled study.

    • 2024-03-11
    • RCT · n = 58
    • European journal of clinical nutrition 78(6)
    • • Ke Chen
      • Shanshan Jin
      • Yu Ma
      • Limei Cai
      • Ping Xu
      • Yang Nie
      • Li Luo
      • Qinghua Yu
      • Yang Shen
      • Zengyuan Zhou
      • Changqi Liu

    • PubMed: 38467857
    • DOI: 10.1038/s41430-024-01428-6

    3 Insights on

    • Reduced Duration of Diarrhea
    • Reduced Diarrhea Rate
    • Increased Cathelicidin Level

    • High evidence
    • Rigorous Journal
• March 12

  • An Updated View of the Effect of Probiotic Supplement on Sports Performance: A Detailed Review.

    • 2024-03-12
    • Review
    • Current nutrition reports 13(2)
    • • Miray Nur Aykut
      • Esma Nur Erdoğan
      • Menşure Nur Çelik
      • Murat Gürbüz

    • PubMed: 38470560
    • DOI: 10.1007/s13668-024-00527-x

    4 Insights on

    • Reduced Gastrointestinal Symptoms
    • Improved Immune Function
    • Improved Exercise Performance
    • Enhanced Nutrient Bioavailability

    • Low evidence

  • Adjuvant treatment with Cordyceps sinensis for lung cancer: A systematic review and meta-analysis of randomized controlled trials.

    • 2024-03-12
    • Meta-Analysis · n = 928
    • Journal of ethnopharmacology 327
    • • Canran Wang
      • Jiawei Wang
      • Yuanfu Qi

    • PubMed: 38484953
    • DOI: 10.1016/j.jep.2024.118044

    7 Insights on

    • Enhanced Natural Killer Cell Tumoricidal Activity
    • Increased Immunoglobulin G Levels
    • Increased Cellulolytic Bacterial Count
    • Increased Serum Immunoglobulin A (IgA) Levels
    • Increased CD4+ T Cell Count
    • Improved Tumor Response
    • Improved Karnofsky Performance Status

    • High evidence
• March 13

  • Effects of Bifidobacterium longum BB536 and Bifidobacterium breve MCC1274 on Body Composition in Normal and Overweight Adults in Randomized Placebo-Controlled Study.

    • 2024-03-13
    • RCT
    • Nutrients 16(6)
    • • Soichiro Sato
      • Satoshi Arai
      • Kumiko Kato
      • Keisuke Yoshida
      • Noriyuki Iwabuchi
      • Toru Sagami
      • Miyuki Tanaka

    • PubMed: 38542727
    • DOI: 10.3390/nu16060815

    4 Insights on

    • Reduced Body Mass Index
    • Reduced Visceral Fat
    • Reduced Abdominal Fat
    • Reduced Serum Triglycerides

    • High evidence
    • Rigorous Journal
• March 15

  • Understanding Ligilactobacillus salivarius from Probiotic Properties to Omics Technology: A Review.

    • 2024-03-15
    • Review
    • Foods (Basel, Switzerland) 13(6)
    • • Yong Yang
      • Xin Song
      • Guangqiang Wang
      • Yongjun Xia
      • Zhiqiang Xiong
      • Lianzhong Ai

    • PubMed: 38540885
    • DOI: 10.3390/foods13060895

    1 Insight on

    • Improved Gut Microbiota Composition

    • Low evidence
• March 19

  • Probiotics supplementation during pregnancy or infancy on multiple food allergies and gut microbiota: a systematic review and meta-analysis.

    • 2024-03-19
    • Meta-Analysis
    • Nutrition reviews 83(2)
    • • Lan Jiang
      • Lili Zhang
      • Jiayue Xia
      • Lei Cheng
      • Guoxun Chen
      • Jin Wang
      • Vijaya Raghavan

    • PubMed: 38502006
    • DOI: 10.1093/nutrit/nuae024

    2 Insights on

    • Reduced Allergic Reaction Risk
    • Reduced Cow-Milk Allergy Risk

    • High evidence
• March 21

  • Current Uses of Bromelain in Children: A Narrative Review.

    • 2024-03-21
    • Review
    • Children (Basel, Switzerland) 11(3)
    • • Cristian Locci
      • Elena Chicconi
      • Roberto Antonucci

    • PubMed: 38539412
    • DOI: 10.3390/children11030377

    3 Insights on

    • Reduced Upper Respiratory Tract Infection Symptoms
    • Improved Dental Health
    • Improved Burn Healing

    • Low evidence
• March 22

  • Effect of peppermint inhalation versus Swedish massage on chemotherapy induced-nausea and vomiting in children with leukemia: Multi-arm randomised trial design.

    • 2024-03-22
    • RCT · n = 25
    • Journal of pediatric nursing 77
    • • Eman Arafa Badr
      • Hawaa Mohamed Abdalla
      • Yousr Abd-Elsalam Gaafer
      • Maha Youssef Kamel

    • PubMed: 38518690
    • DOI: 10.1016/j.pedn.2024.03.019

    1 Insight on

    • Reduced Chemotherapy-Induced Nausea and Vomiting

    • High evidence

  • Lactobacillus casei Shirota probiotic drinks reduce antibiotic associated diarrhoea in patients with spinal cord injuries who regularly consume proton pump inhibitors: a subgroup analysis of the ECLISP multicentre RCT.

    • 2024-03-22
    • RCT · n = 50
    • Spinal cord 62(5)
    • • Samford Wong
      • Shashivadan P Hirani
      • Alastair Forbes
      • Naveen Kumar
      • Ramaswamy Hariharan
      • Jean O'Driscoll
      • Ravi Sekhar
      • Ali Jamous

    • PubMed: 38519563
    • DOI: 10.1038/s41393-024-00983-w

    1 Insight on

    • Reduced Diarrhea Rate

    • High evidence
• March 25

  • Investigating the Neuroprotective and Cognitive-Enhancing Effects of Bacopa monnieri: A Systematic Review Focused on Inflammation, Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis.

    • 2024-03-25
    • Review
    • Antioxidants (Basel, Switzerland) 13(4)
    • • Luiz José Valotto Neto
      • Matheus Reverete de Araujo
      • Renato Cesar Moretti Junior
      • Nathalia Mendes Machado
      • Rakesh Kumar Joshi
      • Daiene Dos Santos Buglio
      • Caroline Barbalho Lamas
      • Rosa Direito
      • Lucas Fornari Laurindo
      • Masaru Tanaka
      • Sandra Maria Barbalho

    • PubMed: 38671841
    • DOI: 10.3390/antiox13040393

    14 Insights on

    • Improved Cognitive Function
    • Improved Attention Span
    • Improved Delayed Memory
    • Reduced Depression Symptoms
    • Reduced Oxidative Stress
    • Reduced Hyperactivity
    • Reduced Inflammatory Biomarker Level
    • Reduced Anhedonia
    • Reduced Nuclear Factor Kappa B Phosphorylation
    • Improved Emotional Function
    • Improved Sleep Routine
    • Reduced Learning Problems
    • Reduced Impulsivity
    • Reduced Psychiatric Problems

    • Low evidence

  • Comparative Efficacy of Different Protein Supplements on Muscle Mass, Strength, and Physical Indices of Sarcopenia among Community-Dwelling, Hospitalized or Institutionalized Older Adults Undergoing Resistance Training: A Network Meta-Analysis of Randomized Controlled Trials.

    • 2024-03-25
    • Systematic Review · n = 5,272
    • Nutrients 16(7)
    • • Chun-De Liao
      • Shih-Wei Huang
      • Hung-Chou Chen
      • Mao-Hua Huang
      • Tsan-Hon Liou
      • Che-Li Lin

    • PubMed: 38612975
    • DOI: 10.3390/nu16070941

    7 Insights on

    • Increased Muscle Mass
    • Improved Walking Speed
    • Improved Handgrip Strength
    • Increased Handgrip Strength
    • Improved Leg Strength
    • Increased Walking Speed
    • Improved Physical Mobility

    • High evidence
    • Rigorous Journal

  • Exploring the Antioxidative Effects of Ginger and Cinnamon: A Comprehensive Review of Evidence and Molecular Mechanisms Involved in Polycystic Ovary Syndrome (PCOS) and Other Oxidative Stress-Related Disorders.

    • 2024-03-25
    • Review · n = 65
    • Antioxidants (Basel, Switzerland) 13(4)
    • • Sladjana Novakovic
      • Vladimir Jakovljevic
      • Nikola Jovic
      • Kristina Andric
      • Milica Milinkovic
      • Teodora Anicic
      • Bozidar Pindovic
      • Elena Nikolaevna Kareva
      • Vladimir Petrovich Fisenko
      • Aleksandra Dimitrijevic
      • Jovana Joksimovic Jovic

    • PubMed: 38671840
    • DOI: 10.3390/antiox13040392

    4 Insights on

    • Improved Insulin Sensitivity
    • Reduced Body Weight
    • Improved Blood Lipid Profile
    • Improved Hormonal Status

    • Moderate evidence
• March 26

  • Evaluation of Potential Probiotic Properties and In Vivo Safety of Lactic Acid Bacteria and Yeast Strains Isolated from Traditional Home-Made Kefir.

    • 2024-03-26
    • Foods (Basel, Switzerland) 13(7)
    • • Angela Maione
      • Marianna Imparato
      • Annalisa Buonanno
      • Maria Michela Salvatore
      • Federica Carraturo
      • Elisabetta de Alteriis
      • Marco Guida
      • Emilia Galdiero

    • PubMed: 38611319
    • DOI: 10.3390/foods13071013

    5 Insights on

    • Improved Gut Health
    • Improved Safety Profile
    • Potential Probiotic Benefits
    • Improved Gastrointestinal Function
    • No Evident Toxicity

    • Low evidence
• March 27

  • Linking human milk oligosaccharide metabolism and early life gut microbiota: bifidobacteria and beyond.

    • 2024-03-27
    • Review
    • Microbiology and molecular biology reviews : MMBR 88(1)
    • • Cathy Lordan
      • Aoife K Roche
      • Dianne Delsing
      • Arjen Nauta
      • Andre Groeneveld
      • John MacSharry
      • Paul D Cotter
      • Douwe van Sinderen

    • PubMed: 38206006
    • DOI: 10.1128/mmbr.00094-23

    1 Insight on

    • Improved Gut Microbiota Composition

    • Low evidence

  • A Mini Literature Review of Probiotics: Transforming Gastrointestinal Health Through Evidence-Based Insights.

    • 2024-03-27
    • Review
    • Cureus 16(3)
    • • Cara Mohammed
      • Jhon P Fuego
      • Karina V Garcia
      • Hira Jamil
      • Rahul Y Rajesh
      • Andres S Escobar
      • Muhammad J Hassan
      • Manju Rai

    • PubMed: 38681263
    • DOI: 10.7759/cureus.57055

    4 Insights on

    • Reduced Diarrhea Incidence
    • Reduced Constipation
    • Improved Gastrointestinal Symptoms
    • Increased Bowel Movements

    • Low evidence

  • Artemisia spp. Essential Oils: From Their Ethnobotanical Use to Unraveling the Microbiota Modulation Potential.

    • 2024-03-27
    • Plants (Basel, Switzerland) 13(7)
    • • Flavio Polito
      • Mattia Di Mercurio
      • Silvia Rizzo
      • Maura Di Vito
      • Maurizio Sanguinetti
      • Andrea Urbani
      • Francesca Bugli
      • Vincenzo De Feo

    • PubMed: 38611496
    • DOI: 10.3390/plants13070967

    1 Insight on

    • Enhanced Probiotic Growth

    • Low evidence

  • Acute toxicity and anti-enterotoxigenic activity of pigment extracted from Micrococcus roseus.

    • 2024-03-27
    • Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] 55(2)
    • • Mahmoud Yolmeh
      • Morteza Khomeiri
      • Ezzatollah Ghaemi
      • Mehmet Selim Şilbir

    • PubMed: 38532186
    • DOI: 10.1007/s42770-024-01316-y

    1 Insight on

    • No Acute Liver Toxicity

    • Low evidence
    • Animal Study
• March 28

  • Soy Product Consumption and the Risk of Cancer: A Systematic Review and Meta-Analysis of Observational Studies.

    • 2024-03-28
    • Meta-Analysis · n = 52
    • Nutrients 16(7)
    • • Chenting Wang
      • Keqing Ding
      • Xuanzhen Xie
      • Jinyue Zhou
      • Pengju Liu
      • Shuang Wang
      • Ting Fang
      • Guozhang Xu
      • Chunlan Tang
      • Hang Hong

    • PubMed: 38613019
    • DOI: 10.3390/nu16070986

    1 Insight on

    • Reduced Cancer Risk

    • High evidence
    • Rigorous Journal

  • Bacillus subtilis SOM8 isolated from sesame oil meal for potential probiotic application in inhibiting human enteropathogens.

    • 2024-03-28
    • BMC microbiology 24(1)
    • • Zhongtian Zhao
      • Wenrui Li
      • The Thien Tran
      • Say Chye Joachim Loo

    • PubMed: 38539071
    • DOI: 10.1186/s12866-024-03263-y

    4 Insights on

    • Reduced Cytotoxicity
    • Improved Antioxidant Activity
    • Improved Stress Tolerance
    • Improved Gastrointestinal Pathogen Inhibition

    • Low evidence

  • A prospective, randomized, open-label, placebo-controlled comparative study of Bacillus coagulans GBI-30,6086 with digestive enzymes in improving indigestion in geriatric population

    • 2024-03-28
    • RCT · n = 50
    • Journal of Family Medicine and Primary Care 9(2)
    • • KulurMukhyaprana Sudha
      • VVasanth Kumar
      • Shilpa Bennur
      • KarukkupalayamRamasamy Dhanasekar

    • PubMed: 32318476
    • DOI: 10.4103/jfmpc.jfmpc_922_19

    1 Insight on

    • Improved Indigestion Symptoms

    • High evidence
    • Rigorous Journal
• Undated – 6 supplement studies

  • Selenium Supplementation in Patients with Hashimoto Thyroiditis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

    • 2024-03
    • Meta-Analysis · n = 2,358
    • Thyroid : official journal of the American Thyroid Association 34(3)
    • • Valentina V Huwiler
      • Stephanie Maissen-Abgottspon
      • Zeno Stanga
      • Stefan Mühlebach
      • Roman Trepp
      • Lia Bally
      • Arjola Bano

    • PubMed: 38243784
    • DOI: 10.1089/thy.2023.0556

    11 Insights on

    • Reduced Interleukin-6 Levels
    • Increased Interleukin-10 Levels
    • Reduced Malondialdehyde
    • Reduced Thyroid Peroxidase Antibody Level
    • Reduced Thyroglobulin Antibody Level
    • Reduced Thyrotropin Level
    • Reduced Free Thyroxine
    • Reduced Total Thyroxine Level
    • Reduced Free Triiodothyronine
    • Reduced Total Triiodothyronine
    • Reduced Thyroid Volume

    • High evidence

  • Bifidobacterium breve M-16V regulates the autonomic nervous system via the intestinal environment: A double-blind, placebo-controlled study.

    • 2024-03
    • RCT
    • Behavioural brain research 460
    • • Natsumi Mutoh
      • Masamichi Moriya
      • Chendong Xu
      • Kumiko Kato
      • Satoshi Arai
      • Noriyuki Iwabuchi
      • Miyuki Tanaka
      • Yin Jinghua
      • Ronko Itamura
      • Kaoru Sakatani
      • Shinichi Warisawa

    • PubMed: 38128887
    • DOI: 10.1016/j.bbr.2023.114820

    2 Insights on

    • Improved Sleep Quality
    • Improved Mood

    • High evidence

  • Metabolomics analysis of okara probiotic beverages fermented with Lactobacillus gasseri and Limosilactobacillus fermentum by LC-QTOF-MS/MS.

    • 2024-03
    • Food chemistry: X 21
    • • Zihan Gao
      • Melody Chang Zhou
      • Jing Lin
      • Yuyun Lu
      • Shao Quan Liu

    • PubMed: 38357377
    • DOI: 10.1016/j.fochx.2024.101178

    3 Insights on

    • Increased Levels of Beneficial Metabolites
    • Reduced Acidity
    • No Human Health Outcome Reported

    • Low evidence

  • Effect of Medicago sativa seed powder (Plus vitamin E vs. vitamin E alone) on semen analysis in men with idiopathic infertility: A double blind randomized clinical trial.

    • 2024-03
    • RCT · n = 60
    • Journal of ethnopharmacology 322
    • • Azita Sadough Shahmirzadi
      • Hamid Shafi
      • Hoda Shirafkan
      • Zahra Memariani
      • Narjes Gorji
      • Reihaneh Moeini

    • PubMed: 38103848
    • DOI: 10.1016/j.jep.2023.117606

    3 Insights on

    • Improved Sperm Count
    • Improved Sperm Morphology
    • Improved Sperm Motility

    • High evidence

  • Exploring the efficacy of a novel prebiotic-like growth promoter on broiler chicken production performance.

    • 2024-03
    • Clinical Trial
    • Veterinary and animal science 23
    • • Zulfqarul Haq
      • Ankur Rastogi
      • Ramesh Kumar Sharma
      • Pratiksha Raghuwanshi
      • Maninder Singh
      • Azmat Alam Khan
      • Syed Mudasir Ahmad

    • PubMed: 38283334
    • DOI: 10.1016/j.vas.2023.100331

    6 Insights on

    • Increased Antioxidant Activity
    • Reduced Oxidative Stress
    • Reduced Lipid Peroxidation
    • Increased Bifidobacteria Growth
    • Enhanced Protein Efficiency Ratio
    • Improved Growth of Beneficial Bacteria

    • Moderate evidence

  • Effects of L-Carnitine Supplementation on the Rate of Weight Gain and Biomarkers of Environmental Enteric Dysfunction in Children with Severe Acute Malnutrition: A Double-Blind Randomized Controlled Clinical Trial.

    • 2024-03
    • RCT · n = 98
    • The Journal of nutrition 154(3)
    • • Jinat Alam
      • Shah Mohammad Fahim
      • Md Ridwan Islam
      • Md Ashraful Alam
      • Md Amran Gazi
      • Tahmeed Ahmed

    • PubMed: 38331348
    • DOI: 10.1016/j.tjnut.2024.01.031

    5 Insights on

    • Reduced Interleukin-4 Levels
    • Reduced Neopterin Levels
    • Increased Weight Gain Rate
    • Reduced Alpha-1-Antitrypsin Level
    • Reduced Hospital Stay Duration

    • High evidence