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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Effect of Yogurt Fermented by Lactobacillus Fermentum TSI and L. Fermentum S2 Derived from a Mongolian Traditional Dairy Product on Rats with High-Fat-Diet-Induced Obesity
- 2020-05-06
- Foods 9(5)
- - Won-Young Cho
  - Go-Eun Hong
  - Ha-Jung Lee
  - Su-Jung Yeon
  - H. Paik
  - Y. Hosaka
  - Chi-Ho Lee
- PubMed: 32384659
- DOI: 10.3390/foods9050594
2 Insights on
- Reduced Abdominal Fat
- Improved Lipid Metabolism
- Low evidence
- Rigorous Journal
Pediococcus pentosaceus LI05 alleviates DSS‐induced colitis by modulating immunological profiles, the gut microbiota and short‐chain fatty acid levels in a mouse model
- 2020-05-03
- Clinical Trial
- Microbial Biotechnology 13(4)
- - Xiaoyuan Bian
  - Liya Yang
  - Wen-rui Wu
  - L. Lv
  - Xianwan Jiang
  - Qing Wang
  - Jingjing Wu
  - Yating Li
  - Jianzhong Ye
  - D. Fang
  - D. Shi
  - Kaicen Wang
  - Qiangqiang Wang
  - Yanmeng Lu
  - Jiaojiao Xie
  - Jiafeng Xia
  - Lanjuan Li
- PubMed: 32363766
- DOI: 10.1111/1751-7915.13583
8 Insights on
- Low evidence
- Animal Study
Radix Astragali and Radix Angelicae Sinensis in the Treatment of Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-analysis.
- 2020-04-30
- Systematic Review
- Frontiers in pharmacology 11
- - Yufeng Zhang
  - Lina Gu
  - Qingqing Xia
  - Lijun Tian
  - Jia Qi
  - Mengshu Cao
- PubMed: 32425767
- DOI: 10.3389/fphar.2020.00415
5 Insights on
- High evidence
The Effect of Lactobacillus plantarum 299v on Iron Status and Physical Performance in Female Iron-Deficient Athletes: A Randomized Controlled Trial.
- 2020-04-30
- RCT
- Nutrients 12(5)
- - Ulrika Axling
  - Gunilla Önning
  - Maile A Combs
  - Alemtsehay Bogale
  - Magnus Högström
  - Michael Svensson
- PubMed: 32365981
- DOI: 10.3390/nu12051279
4 Insights on
- High evidence
- Rigorous Journal
Influenza infection elicits an expansion of gut population of endogenous Bifidobacterium animalis which protects mice against infection
- 2020-04-28
- Clinical Trial
- Genome Biology 21(1)
- - Qiang Zhang
  - Jin Hu
  - Jia-Wu Feng
  - Xiaotong Hu
  - Ting Wang
  - Wen-xiao Gong
  - Kun Huang
  - Yi-Xiong Guo
  - Zhong Zou
  - Xian Lin
  - Run Zhou
  - Yuting Yuan
  - A. Zhang
  - Hong Wei
  - Gang Cao
  - Chen Liu
  - Lingling Chen
  - M. Jin
- PubMed: 32345342
- DOI: 10.1186/s13059-020-02007-1
3 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Suppression of Oral Sweet Sensations during Consumption of Sweet Food in Humans: Effects on Gastric Emptying Rate, Glycemic Response, Appetite, Food Satisfaction and Desire for Basic Tastes.
- 2020-04-28
- RCT
- Nutrients 12(5)
- - Naomi Kashima
  - Kanako Kimura
  - Natsumi Nishitani
  - Masako Yamaoka Endo
  - Yoshiyuki Fukuba
  - Hideaki Kashima
- PubMed: 32353974
- DOI: 10.3390/nu12051249
4 Insights on
- High evidence
- Rigorous Journal
Antioxidant and Anti-Inflammatory Effect of Probiotic Lactobacillus plantarum KU15149 Derived from Korean Homemade Diced-Radish Kimchi
- 2020-04-28
- Journal of Microbiology and Biotechnology 30(4)
- - Kyoung Jun Han
  - Ji-Eun Lee
  - N. Lee
  - H. Paik
- PubMed: 32238771
- DOI: 10.4014/jmb.2002.02052
10 Insights on
- Low evidence
Potential Health-Promoting Benefits of Paraprobiotics, Inactivated Probiotic Cells.
- 2020-04-28
- Review
- Journal of microbiology and biotechnology 30(4)
- - Shahina Akter
  - Jong-Hyun Park
  - Hoo Kil Jung
- PubMed: 31986247
- DOI: 10.4014/jmb.1911.11019
3 Insights on
- Low evidence
Lactobacillus plantarum NA136 ameliorates nonalcoholic fatty liver disease by modulating gut microbiota, improving intestinal barrier integrity, and attenuating inflammation
- 2020-04-26
- Clinical Trial
- Applied Microbiology and Biotechnology 104(12)
- - Zijian Zhao
  - Long Chen
  - Yujuan Zhao
  - Chao Wang
  - Cui-cui Duan
  - Ge Yang
  - Chunhua Niu
  - Shengyu Li
- PubMed: 32335723
- DOI: 10.1007/s00253-020-10633-9
7 Insights on
- Low evidence
- Animal Study
A double-blind, randomized, crossover trial protocol of whole hemp seed protein and hemp seed protein hydrolysate consumption for hypertension.
- 2020-04-23
- RCT
- Trials 21(1)
- - Maryam Samsamikor
  - Dylan Mackay
  - Rebecca C Mollard
  - Rotimi E Aluko
- PubMed: 32326966
- DOI: 10.1186/s13063-020-4164-z
4 Insights on
- High evidence
Efficacy of Lactobacillus paracasei HA-196 and Bifidobacterium longum R0175 in Alleviating Symptoms of Irritable Bowel Syndrome (IBS): A Randomized, Placebo-Controlled Study
- 2020-04-21
- RCT · n = 251
- Nutrients 12(4)
- - E. Lewis
  - Joseph M. Antony
  - David C. Crowley
  - A. Piano
  - R. Bhardwaj
  - T. Tompkins
  - M. Evans
- PubMed: 32326347
- DOI: 10.3390/nu12041159
15 Insights on
- High evidence
Safety and Effect of a Low- and High-Dose Multi-Strain Probiotic Supplement on Microbiota in a General Adult Population: A Randomized, Double-Blind, Placebo-Controlled Study
- 2020-04-20
- RCT
- Journal of Dietary Supplements 18(3)
- - A. Tremblay
  - Asmaa Fatani
  - A. Ford
  - A. Piano
  - Varuni Nagulesapillai
  - J. Auger
  - Chad W. MacPherson
  - M. Christman
  - T. Tompkins
  - W. Dahl
- PubMed: 32306803
- DOI: 10.1080/19390211.2020.1749751
2 Insights on
- No Adverse Events Observed
- No Significant Change in Gastrointestinal or General Wellbeing
- High evidence
Herbal treatments for migraine: A systematic review of randomised-controlled studies.
- 2020-04-20
- Systematic Review
- Phytotherapy research : PTR 34(10)
- - Adrian L Lopresti
  - Stephen J Smith
  - Peter D Drummond
- PubMed: 32310327
- DOI: 10.1002/ptr.6701
3 Insights on
- High evidence
Reduction in the Choking Phenomenon in Elite Diving Athletes Through Changes in Gut Microbiota Induced by Yogurt Containing Bifidobacterium animalis subsp. lactis BB-12: A Quasi Experimental Study.
- 2020-04-20
- Clinical Trial · n = 20
- Microorganisms 8(4)
- - Weizhong Dong
  - Ying Wang
  - Shuaixiong Liao
  - Minghang Lai
  - Li Peng
  - Gang Song
- PubMed: 32326047
- DOI: 10.3390/microorganisms8040597
4 Insights on
- Moderate evidence
A Randomized Controlled Open Label Crossover Trial to Study Vaginal Colonization of Orally Administered Lactobacillus Reuteri RC-14 and Rhamnosus GR-1 in Pregnant Women at High Risk for Preterm Labor
- 2020-04-19
- RCT · n = 40
- Nutrients 12(4)
- - Enav Yefet
  - R. Colodner
  - M. Strauss
  - Yifat Gam Ze Letova
  - Z. Nachum
- PubMed: 32325794
- DOI: 10.3390/nu12041141
1 Insight on
- Reduced Vaginal Colonization
- High evidence
Effects of Clostridium butyricum and Enterococcus faecalis on growth performance, immune function, intestinal morphology, volatile fatty acids, and intestinal flora in a piglet model.
- 2020-04-16
- RCT · n = 180
- Food & Function 10(12)
- - Kangli Wang
  - G. Cao
  - Haoran Zhang
  - Qing Li
  - Caimei Yang
- PubMed: 31793606
- DOI: 10.1039/c9fo01650c
4 Insights on
- Low evidence
- Highly Cited
- Animal Study
Integrated metabolomic and proteomics profiling reveals the promotion of Lactobacillus reuteri LR1 on amino acid metabolism in the gut-liver axis of weaned pigs.
- 2020-04-16
- Clinical Trial
- Food & Function 10(11)
- - H. Yi
  - G. Yang
  - Yunxia Xiong
  - Qiwen Wu
  - Hao Xiao
  - XiaoLu Wen
  - Xuefen Yang
  - Li Wang
  - Zong-yong Jiang
- PubMed: 31651917
- DOI: 10.1039/c9fo01781j
2 Insights on
- Enhanced Amino Acid Metabolism
- Increased mTORC1 Activation
- Low evidence
- Animal Study
Supplemental Clostridium butyricum Modulates Lipid Metabolism Through Shaping Gut Microbiota and Bile Acid Profile of Aged Laying Hens
- 2020-04-15
- Frontiers in Microbiology 11
- - Wei-wei Wang
  - Jing Wang
  - Haijun Zhang
  - Shu-geng Wu
  - G. Qi
- PubMed: 32351471
- DOI: 10.3389/fmicb.2020.00600
5 Insights on
- Low evidence
Molecular Routes to Specific Identification of the Lactobacillus Casei Group at the Species, Subspecies and Strain Level
- 2020-04-13
- International Journal of Molecular Sciences 21(8)
- - P. Jarocki
  - Elwira Komoń-Janczara
  - A. Glibowska
  - M. Dworniczak
  - Monika Pytka
  - A. Korzeniowska-Kowal
  - A. Wzorek
  - M. Kordowska-Wiater
- PubMed: 32294944
- DOI: 10.3390/ijms21082694
8 Insights on
- Low evidence
A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning.
- 2020-04-10
- Systematic Review
- Journal of dietary supplements 18(3)
- - Asako M Kikuchi
  - Aya Tanabe
  - Yoshihiro Iwahori
- PubMed: 32272859
- DOI: 10.1080/19390211.2020.1746725
3 Insights on
- High evidence
Lactobacillus salivarius Subspecies salicinius SA-03 is a New Probiotic Capable of Enhancing Exercise Performance and Decreasing Fatigue
- 2020-04-09
- Microorganisms 8(4)
- - Mon-Chien Lee
  - Y. Hsu
  - H. Ho
  - Shih‐Hung Hsieh
  - Y. Kuo
  - Hsin‐Ching Sung
  - Chi-Chang Huang
- PubMed: 32283729
- DOI: 10.3390/microorganisms8040545
13 Insights on
- Low evidence
- Rigorous Journal
Fecal Recovery of Probiotics Administered as a Multi-Strain Formulation during Antibiotic Treatment.
- 2020-04-09
- RCT
- Biomedicines 8(4)
- - Sofia D Forssten
  - Nicolas Yeung
  - Arthur C Ouwehand
- PubMed: 32283645
- DOI: 10.3390/biomedicines8040083
1 Insight on
- Increased Persistence of Probiotics in Fecal Matter
- High evidence
Harnessing Microbes for Sustainable Development: Food Fermentation as a Tool for Improving the Nutritional Quality of Alternative Protein Sources.
- 2020-04-08
- Review
- Nutrients 12(4)
- - Anna Kårlund
  - Carlos Gómez-Gallego
  - Jenni Korhonen
  - Outi-Maaria Palo-Oja
  - Hani El-Nezami
  - Marjukka Kolehmainen
- PubMed: 32276384
- DOI: 10.3390/nu12041020
6 Insights on
- Moderate evidence
- Rigorous Journal
Lactobacillus pentosus S-PT84 Prevents Low-Grade Chronic Inflammation-Associated Metabolic Disorders in a Lipopolysaccharide and High-Fat Diet C57/BL6J Mouse Model.
- 2020-04-06
- Clinical Trial
- Journal of Agricultural and Food Chemistry 68(15)
- - Yuhan Zeng
  - Hua Zhang
  - R. Tsao
  - Y. Mine
- PubMed: 32250610
- DOI: 10.1021/acs.jafc.0c00118
3 Insights on
- Low evidence
- Animal Study
Effects of Palmaria palmata on lipid metabolism and glycemic control in participants with hypercholesterolemia in a randomized double-blind placebo-controlled trial.
- 2020-04-03
- RCT · n = 104
- Phytotherapy research : PTR 34(9)
- - Takahiro Takase
  - Akinobu Nakamura
  - Hideaki Miyoshi
  - Minori Koga
  - Atsuhito Toyomaki
  - Ichiro Kusumi
  - Rikako Kino
  - Yasuyuki Konishi
  - Yoshinobu Kiso
  - Tatsuya Atsumi
- PubMed: 32242987
- DOI: 10.1002/ptr.6680
1 Insight on
- Reduced Triglyceride Levels
- High evidence
- Large Human Trial
Effects of Lactobacillus rhamnosus ATCC 7469 on Different Parameters Related to Health Status of Rainbow Trout (Oncorhynchus mykiss) and the Protection Against Yersinia ruckeri
- 2020-04-03
- Probiotics and Antimicrobial Proteins 12(4)
- - Yalda Hooshyar
  - A. Abedian Kenari
  - H. Paknejad
  - H. Gandomi
- PubMed: 32246325
- DOI: 10.1007/s12602-020-09645-8
8 Insights on
- Low evidence
Lactobacillus acidophilus and L. plantarum improve health status, modulate gut microbiota and innate immune response of marron (Cherax cainii)
- 2020-04-03
- RCT · n = 36
- Scientific Reports 10(1)
- - Md Javed Foysal
  - R. Fotedar
  - M. Siddik
  - A. Tay
- PubMed: 32246011
- DOI: 10.1038/s41598-020-62655-y
9 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Does Streptococcus Salivarius Strain M18 Assumption Make Black Stains Disappear in Children?
- 2020-04-03
- RCT · n = 29
- Oral health & preventive dentistry 18(2)
- - Elena Bardellini
  - Francesca Amadori
  - Emanuela Gobbi
  - Anna Ferri
  - Giulio Conti
  - Alessandra Majorana
- PubMed: 32099975
- DOI: 10.3290/j.ohpd.a43359
1 Insight on
- Reduced Black Stain Recurrence
- High evidence
Bifidobacterium longum subsp. longum remodeled Roseburia and Phosphatidylserine levels, meliorated intestinal disorders and liver metabolic abnormalities induced by high-fat diet.
- 2020-04-02
- Clinical Trial
- Journal of Agricultural and Food Chemistry 68(16)
- - Tao Wu
  - Mengzhen Sun
  - R. Liu
  - Wenjie Sui
  - Jiaojiao Zhang
  - Jinjin Yin
  - Jiangu Zhu
  - S. Fang
  - Min Zhang
- PubMed: 32237746
- DOI: 10.1021/acs.jafc.0c00717
17 Insights on
- Low evidence
- Animal Study
Influence of Lactobacillus kefiri on Intestinal Microbiota and Fecal IgA Content of Healthy Dogs
- 2020-04-02
- Clinical Trial · n = 10
- Frontiers in Veterinary Science 7
- - A. Gaspardo
  - A. Zannoni
  - S. Turroni
  - M. Barone
  - M. C. Sabetti
  - R. Zanoni
  - M. Forni
  - P. Brigidi
  - M. Pietra
- PubMed: 32300601
- DOI: 10.3389/fvets.2020.00146
1 Insight on
- Unchanged Fecal IgA Levels
- Low evidence
- Animal Study