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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Biomedical role of L-carnitine in several organ systems, cellular tissues, and COVID-19.
- 2022
- Review
- Brazilian journal of biology = Revista brasleira de biologia 82
- - I S Al-Dhuayan
- PubMed: 36629544
- DOI: 10.1590/1519-6984.267633
4 Insights on
- Low evidence
Effectiveness of nursing interventions in preventing and treating radiotherapy side effects in cancer patients: a systematic review.
- 2021
- Systematic Review
- Revista da Escola de Enfermagem da U S P 55
- - Aline Moraes de Abreu
  - Duan Renato da Silva Fraga
  - Bruna Bastos Giergowicz
  - Rosália Borges Figueiró
  - Roberta Waterkemper
- PubMed: 33978137
- DOI: 10.1590/s1980-220x2019026303697
1 Insight on
- Reduced Radiodermatitis
- High evidence
Live and ultrasound-inactivated Lacticaseibacillus casei modulate the intestinal microbiota and improve biochemical and cardiovascular parameters in male rats fed a high-fat diet.
- 2021
- Clinical Trial · n = 24
- Food & Function 12(12)
- - Larissa Ramalho Brandão
  - J. L. de Brito Alves
  - W. K. A. da Costa
  - Georgianna de Araújo Henriques Ferreira
  - Matthaws Pereira de Oliveira
  - A. Gomes da Cruz
  - V. Braga
  - J. Aquino
  - H. Vidal
  - M. F. Noronha
  - Lucélia Cabral
  - T. C. Pimentel
  - M. Magnani
- PubMed: 34009228
- DOI: 10.1039/d1fo01064f
9 Insights on
- Low evidence
- Animal Study
Lactobacillus fermentum CQPC08 protects rats from lead-induced oxidative damage by regulating the Keap1/Nrf2/ARE pathway.
- 2021
- Clinical Trial
- Food & Function 12(13)
- - X. Long
  - F. Sun
  - Zhiying Wang
  - Tongjin Liu
  - Jianjun Gong
  - Xuemei Kan
  - Yujie Zou
  - Xin Zhao
- PubMed: 34037025
- DOI: 10.1039/d1fo00589h
8 Insights on
- Low evidence
- Animal Study
Chia seed (Salvia hispanica L.) consumption and lipid profile: a systematic review and meta-analysis.
- 2021
- Meta-Analysis
- Food & function 12(19)
- - Luciana de Abreu Silva
  - Bárbara Júlia Fonseca Verneque
  - Ana Paula Lucas Mota
  - Camila Kümmel Duarte
- PubMed: 34378609
- DOI: 10.1039/d1fo01287h
4 Insights on
- High evidence
- Rigorous Journal
The effect of Plantago major supplementation on leptin and VEGF-A serum levels, endothelial dysfunction and angiogenesis in obese women - a randomised trial.
- 2021
- RCT · n = 37
- Food & function 12(4)
- - Damian Skrypnik
  - Katarzyna Skrypnik
  - Marta Pelczyńska
  - Magdalena Sobieska
  - Alexey A Tinkov
  - Joanna Suliburska
  - Paweł Bogdański
- PubMed: 33502416
- DOI: 10.1039/d0fo01878c
1 Insight on
- Increased Leptin Levels
- High evidence
- Rigorous Journal
[Dynamics of cognitive impairments during L-dopa therapy in Parkinson's disease].
- 2021
- RCT · n = 41
- Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 121(7)
- - S B Ismailova
  - S V Prokopenko
  - D V Pokhabov
  - E I Mosaleva
  - P V Alekseenko
  - I M Zhumzhanov
- PubMed: 34460155
- DOI: 10.17116/jnevro202112107136
4 Insights on
- High evidence
Probiotics in irritable bowel syndrome - is the quest for the right strain over? Rapid review of existing guidelines and recommendations.
- 2021
- Review
- Przeglad gastroenterologiczny 16(4)
- - Wojciech Marlicz
  - Karolina Skonieczna-Żydecka
  - Patrycja Krynicka
  - Igor Łoniewski
  - Grażyna Rydzewska
- PubMed: 34976247
- DOI: 10.5114/pg.2021.111766
2 Insights on
- Reduced Global Symptoms
- Reduced Global Symptom Persistence
- Low evidence
The effects of rice bran oil on left ventricular systolic function, cardiometabolic risk factors and inflammatory mediators in men with coronary artery disease: a randomized clinical trial.
- 2021
- RCT · n = 40
- Food & function 12(10)
- - Marjan Mahdavi-Roshan
  - Arsalan Salari
  - Zeinab Ghorbani
  - Zahra Nikpey
  - Motahare Haghighatkhah
  - Aboozar Fakhr Mousavi
  - Mahboobeh Gholipour
  - Amir Pourfarzad
- PubMed: 33881115
- DOI: 10.1039/d1fo00094b
11 Insights on
- High evidence
- Rigorous Journal
Impact of encapsulating a probiotic (Pediococcus pentosaceus Li05) within gastro-responsive microgels on Clostridium difficile infections.
- 2021
- Clinical Trial
- Food & Function 12(7)
- - Jiaojiao Xie
  - Mingfei Yao
  - Yanmeng Lu
  - Mengjia Yu
  - Shengyi Han
  - D. Mcclements
  - Hang Xiao
  - Lanjuan Li
- PubMed: 33734244
- DOI: 10.1039/d0fo03235b
5 Insights on
- Low evidence
- Animal Study
Effects of Pediococcus pentosaceus LI05 on immunity and metabolism in germ-free rats.
- 2021
- Clinical Trial
- Food & Function 12(11)
- - Shiman Jiang
  - Jiafeng Xia
  - L. Lv
  - Qiangqiang Wang
  - Yating Li
  - Qiaomai Xu
  - Xiaoyuan Bian
  - Jianzhong Ye
  - Liya Yang
  - Huiyong Jiang
  - Ren Yan
  - Kaicen Wang
  - D. Fang
  - Lanjuan Li
- PubMed: 33960989
- DOI: 10.1039/d0fo02530e
7 Insights on
- Low evidence
- Animal Study
Potential prebiotic properties of exopolysaccharides produced by a novel Lactobacillus strain, Lactobacillus pentosus YY-112.
- 2021
- Food & Function 12(19)
- - Mingzhe Wang
  - Wanyi Zhou
  - Ying Yang
  - Jianrong Xing
  - Xiaodan Xu
  - Yuqing Lin
- PubMed: 34606528
- DOI: 10.1039/d1fo01261d
3 Insights on
- Low evidence
Biological effects of stevia, sucralose and sucrose in citrus-maqui juices on overweight subjects.
- 2021
- RCT
- Food & function 12(18)
- - Pilar Zafrilla
  - Hedyeh Masoodi
  - Begoña Cerdá
  - Cristina García-Viguera
  - Débora Villaño
- PubMed: 34323244
- DOI: 10.1039/d1fo01160j
4 Insights on
- High evidence
- Rigorous Journal
Moringa oleifera capsule and diet in young women with dropout school.
- 2021
- RCT
- Gaceta sanitaria 35
- - Suhartini
  - Veni Hadju
  - Samricard R
  - Alimuddin Unde
  - Nurjaqin
  - Burhanuddin Bahar
- PubMed: 34929814
- DOI: 10.1016/j.gaceta.2021.10.023
1 Insight on
- Improved Diet
- High evidence
Screening of Lactobacillus salivarius strains from the feces of Chinese populations and the evaluation of their effects against intestinal inflammation in mice.
- 2020
- Food & Function 11(1)
- - Q. Zhai
  - Xudan Shen
  - Shi Cen
  - Chengcheng Zhang
  - F. Tian
  - Jianxin Zhao
  - Hao Zhang
  - Yuzheng Xue
  - Wei Chen
- PubMed: 31915776
- DOI: 10.1039/c9fo02116g
8 Insights on
- Low evidence
The ameliorative effect of Lactobacillus plantarum Y44 oral administration on inflammation and lipid metabolism in obese mice fed with a high fat diet.
- 2020
- Clinical Trial
- Food & Function 11(6)
- - Yujun Liu
  - Yuan Gao
  - Fenglian Ma
  - Mengying Sun
  - Guangqing Mu
  - Y. Tuo
- PubMed: 32530448
- DOI: 10.1039/d0fo00439a
7 Insights on
- Low evidence
- Animal Study
Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia.
- 2020
- Review
- Skin appendage disorders 6(6)
- - Evyatar Evron
  - Margit Juhasz
  - Arash Babadjouni
  - Natasha Atanaskova Mesinkovska
- PubMed: 33313047
- DOI: 10.1159/000509905
4 Insights on
- Low evidence
For the love of color: Plant colors and the dermatologist.
- 2020
- Review
- Indian journal of dermatology, venereology and leprology 86(6)
- - Hima Gopinath
  - Kaliaperumal Karthikeyan
  - Valeti Meghana
- PubMed: 33037162
- DOI: 10.4103/ijdvl.ijdvl_402_19
1 Insight on
- Altered Skin Color
- Low evidence
Suppressive effects of Streptococcus thermophilus KLDS 3.1003 on some foodborne pathogens revealed through in vitro, in vivo and genomic insights.
- 2020
- Food & Function 11(7)
- - S. Evivie
  - M. Ogwu
  - Amro Abdelazez
  - Xin Bian
  - Fei Liu
  - Bailiang Li
  - G. Huo
- PubMed: 32647845
- DOI: 10.1039/d0fo01218a
19 Insights on
- Low evidence
The cognitive effects of an acute wild blueberry intervention on 7- to 10-year-olds using extended memory and executive function task batteries.
- 2020
- RCT
- Food & function 11(5)
- - Adrian R Whyte
  - Daniel J Lamport
  - Graham Schafer
  - Claire M Williams
- PubMed: 32426759
- DOI: 10.1039/c9fo02284h
1 Insight on
- Reduced Reaction Time
- High evidence
- Rigorous Journal
Is soy protein effective in reducing cholesterol and improving bone health?
- 2020
- RCT
- Food & function 11(1)
- - Kelli S George
  - Joseph Muñoz
  - Neda S Akhavan
  - Elizabeth M Foley
  - Shalom C Siebert
  - Gershon Tenenbaum
  - Dania A Khalil
  - Sheau C Chai
  - Bahram H Arjmandi
- PubMed: 31848551
- DOI: 10.1039/c9fo01081e
8 Insights on
- High evidence
- Rigorous Journal
Protective effects of Bifidobacterium adolescentis on collagen-induced arthritis in rats depend on timing of administration.
- 2020
- Clinical Trial
- Food & Function 11(5)
- - Zhexin Fan
  - Bo Yang
  - R. Ross
  - C. Stanton
  - Jianxin Zhao
  - G. Shi
  - Hao Zhang
  - Wei Chen
- PubMed: 32383727
- DOI: 10.1039/d0fo00077a
4 Insights on
- Low evidence
- Animal Study
Ingestion of Bifidobacterium longum subspecies infantis strain CCFM687 regulated emotional behavior and the central BDNF pathway in chronic stress-induced depressive mice through reshaping the gut microbiota.
- 2019
- Clinical Trial
- Food & Function 10(11)
- - Peijun Tian
  - Renying Zou
  - Linhong Song
  - Xu Zhang
  - Bin Jiang
  - Gang Wang
  - Yuan-Kun Lee
  - Jianxin Zhao
  - Hao Zhang
  - Wei Chen
- PubMed: 31687714
- DOI: 10.1039/c9fo01630a
16 Insights on
- Low evidence
- Animal Study
The Use of a Combination of Vaccinium Macracarpon, Lycium barbarum L. and Probiotics (Bifiprost®) for the Prevention of Chronic Bacterial Prostatitis: A Double-Blind Randomized Study.
- 2019
- RCT · n = 120
- Urologia internationalis 103(4)
- - Francesco Chiancone
  - Maurizio Carrino
  - Clemente Meccariello
  - Luigi Pucci
  - Maurizio Fedelini
  - Paolo Fedelini
- PubMed: 31527377
- DOI: 10.1159/000502765
2 Insights on
- Reduced Prostatitis Episodes
- Reduced Chronic Prostatitis Symptom Index Score
- High evidence
- Large Human Trial
Influence of Dehydrated Wheat/Rice Cereal Matrices on Probiotic Activity of Bifidobacterium animalis ssp. lactis BB-12®§
- 2019
- Food technology and biotechnology 57(2)
- - A. Leboš-Pavunc
  - Lenkica Penava
  - Jasmina Ranilović
  - Jasna Novak
  - M. Banić
  - Katarina Butorac
  - Emilija Petrović
  - V. Mihaljević-Herman
  - K. Bendelja
  - Ana Savić-Mlakar
  - K. Durgo
  - B. Kos
  - J. Šušković
- PubMed: 31537964
- DOI: 10.17113/ftb.57.02.19.6142
3 Insights on
- Low evidence
Antioxidant Activity and Infrared Spectroscopy Analysis of Alcoholic Extracts Obtained from Paecilomyces hepiali (Ascomycetes).
- 2018
- International Journal of Medicinal Mushrooms 20(6)
- - Lucia Ungvarská Maľučká
  - J. Harvanová
  - A. Uhrinová
  - A. Salayová
  - M. Pavlík
  - Martin Rajtar
- PubMed: 29953355
- DOI: 10.1615/IntJMedMushrooms.2018026548
1 Insight on
- Improved Antioxidant Activity
- Low evidence
Sour cherry extract inhibits human salivary α-amylase and growth of Streptococcus mutans (a pilot clinical study).
- 2018
- Clinical Trial · n = 70
- Food & function 9(7)
- - Judit Homoki
  - Gyöngyi Gyémánt
  - Péter Balogh
  - László Stündl
  - Piroska Bíró-Molnár
  - Melinda Paholcsek
  - Judit Váradi
  - Fenyvesi Ferenc
  - Barna Kelentey
  - Judit Nemes
  - Judit Remenyik
- PubMed: 29978173
- DOI: 10.1039/c8fo00064f
2 Insights on
- Reduced Streptococcus Mutans Levels
- Reduced Salivary Alpha-Amylase Activity
- High evidence
- Rigorous Journal
Effects of Bifidobacterium breve B-3 on body fat reductions in pre-obese adults: a randomized, double-blind, placebo-controlled trial
- 2018
- RCT · n = 80
- Bioscience of Microbiota, Food and Health 37(3)
- - J. Minami
  - N. Iwabuchi
  - Miyuki Tanaka
  - K. Yamauchi
  - J. Xiao
  - F. Abe
  - N. Sakane
- PubMed: 30094122
- DOI: 10.12938/bmfh.18-001
13 Insights on
- High evidence
- Highly Cited
- Rigorous Journal
Lactobacillus casei CCFM419 attenuates type 2 diabetes via a gut microbiota dependent mechanism.
- 2017
- Clinical Trial
- Food & Function 8(9)
- - Gang Wang
  - Xiangfei Li
  - Jianxin Zhao
  - Hao Zhang
  - Wei Chen
- PubMed: 28782784
- DOI: 10.1039/c7fo00593h
10 Insights on
- Low evidence
- Highly Cited
- Animal Study
Vitamins K1 and K2: The Emerging Group of Vitamins Required for Human Health.
- 2017
- Review
- Journal of nutrition and metabolism 2017
- - Gerry Kurt Schwalfenberg
- PubMed: 28698808
- DOI: 10.1155/2017/6254836
8 Insights on
- Low evidence