April 2026 Supplement Research Papers

• April 1

  • The Role of Chemopreventive Agents in the Management of Oral Potentially Malignant Disorders and Oral Cancer: A Narrative Review.

    • 2026-04-01
    • Review
    • Cancer reports (Hoboken, N.J.) 9(4)
    • • Lana Sayal
      • Omar Hamadah
      • Eyad Chatty
      • Anas Abdo
      • Sana Aghbari
      • Ali Munasser
      • Amirah Alnour

    • PubMed: 42032821
    • DOI: 10.1002/cnr2.70559

    2 Insights on

    • Reduced Dysplasia
    • Reduced Malignant Transformation

    • Low evidence

  • The enhancing therapeutic effect of neonatal jaundice by bifidobacterium through regulating inflammation and gut microbiota in combination with phototherapy-a randomized controlled trial.

    • 2026-04-01
    • Clinical Trial · n = 79
    • Frontiers in microbiology 17
    • • Feng Zhang
      • Jiayi Chen
      • Yanhan Yuan
      • Juanjuan Chen
      • Wei Jiang
      • Weiwei Xiang
      • Na Wang
      • Zhimin Wu
      • Sainan Fan
      • Kun Zhang
      • Yanan Ma
      • Tianyu Liu
      • Jiahui Zhang
      • Qinghua Yu
      • Jinping Zhang

    • PubMed: 41994268
    • DOI: 10.3389/fmicb.2026.1761245

    5 Insights on

    • Reduced Bilirubin Levels
    • Reduced Length of Hospital Stay
    • Increased Defecation Frequency
    • Improved Personal-Social Developmental Score
    • Improved Performance Developmental Score

    • High evidence

  • Association of Green Tea Consumption and the Risk of Liver Cancer Incidence among Japanese Adults.

    • 2026-04-01
    • Observational · n = 23,794
    • Asian Pacific journal of cancer prevention : APJCP 27(4)
    • • Ohiroshi Funabashi
      • Ryoto Sakaniwa
      • Ryo Kawasaki
      • Akiko Tamakoshi
      • Hiroyasu Iso

    • PubMed: 41945949
    • DOI: 10.31557/apjcp.2026.27.4.1313

    1 Insight on

    • Reduced Incidence of Liver Cancer

    • High evidence

  • The interplay between probiotics and mast cells in gut inflammation: a mini-review.

    • 2026-04-01
    • Review
    • Frontiers in cellular and infection microbiology 16
    • • Maria Fernanda Herrera-Saldivar
      • Norma Carolina Hernandez-Bautista
      • Juan Manuel Quiroga-Garza
      • Jose Manuel Vazquez-Guillen
      • Rommel Chacon-Salinas
      • Maurilia Rojas-Contreras
      • Ricardo Vazquez-Juarez
      • Diana Resendez-Perez
      • Reyes S Tamez-Guerra
      • Cristina Rodriguez-Padilla

    • PubMed: 41994207
    • DOI: 10.3389/fcimb.2026.1772010

    1 Insight on

    • Modulated Immune Response

    • Low evidence

  • Early-Life Microbiota Modulation and Neurodevelopment in Infants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    • 2026-04-01
    • Meta-Analysis
    • Cells 15(7)
    • • Salvatore Michele Carnazzo
      • Fabio Allia
      • Alice Foti
      • Marilena Briglia
      • Marcello Maida
      • Adriana Carol Eleonora Graziano
      • Andrea Domenico Praticò

    • PubMed: 41972726
    • DOI: 10.3390/cells15070638

    1 Insight on

    • Improved Neurodevelopmental Outcome

    • High evidence

  • Anti-obesity effects of probiotics beyond BMI: a critical review of human clinical trials.

    • 2026-04-01
    • Review
    • Letters in applied microbiology 79(4)
    • • Hewa Athapaththuge Duvini Athapaththu
      • Gargi Dey

    • PubMed: 41921070
    • DOI: 10.1093/lambio/ovag041

    11 Insights on

    • Reduced Waist Circumference
    • Reduced Body Mass Index
    • Reduced Visceral Fat
    • Reduced Body Weight
    • Reduced Body Fat Percentage
    • Improved Lipid Metabolism
    • Reduced Pro-inflammatory Cytokine Levels
    • Improved Homeostasis
    • Improved Appetite
    • Improved Satiety
    • Reduced Total Body Fat

    • Low evidence
• April 2

  • Antioxidants as Therapeutic Tools in the Management of COPD: A Systematic Review with Meta-Analysis.

    • 2026-04-02
    • Review
    • Antioxidants (Basel, Switzerland) 15(4)
    • • Manuel López-Denis
      • Bernardo Cálamo-Guzmán
      • Silvia Castillo-Corullón
      • Joaquín Carrasco-Luna
      • María José Herrero
      • Cruz González-Villaescusa
      • Jaime Signes-Costa
      • Francisco Dasí

    • PubMed: 42072087
    • DOI: 10.3390/antiox15040446

    1 Insight on

    • Reduced Exacerbation Risk

    • Low evidence
• April 3

  • N-Acetylcysteine Therapy in Thrombotic Thrombocytopenic Purpura: A Systematic Review and Critical Appraisal.

    • 2026-04-03
    • Review · n = 69
    • Journal of clinical medicine 15(7)
    • • Ufuk Demirci
      • Zübeyir Talha Bilgin
      • Mehmet Baysal

    • PubMed: 41977015
    • DOI: 10.3390/jcm15072713

    2 Insights on

    • Improved Iron Levels
    • Increased Platelet Count

    • Moderate evidence

  • Lactobacillus casei culture supernatant ameliorates acute alcohol-induced liver injury by inhibiting cellular stress and promoting intestinal integrity in mice.

    • 2026-04-03
    • PloS one 21(4)
    • • Xie Zhang
      • Zhihui Xu
      • Ying You
      • Longteng Xie
      • Yongsheng Jiang
      • Junyue Chen
      • Zeping Xu
      • Feng Xu
      • Deshu Zhou

    • PubMed: 41931531
    • DOI: 10.1371/journal.pone.0344960

    2 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Alcohol-Induced Liver Injury

    • Low evidence
    • Animal Study
• April 4

  • Gut microbiota-driven IL-17/PPAR axis mediates epigallocatechin-induced intestinal repair in weaned lambs.

    • 2026-04-04
    • Journal of animal science and biotechnology 17(1)
    • • Yuwei Zhao
      • Zhuo Wang
      • Dingkun Fan
      • Jixian Zhang
      • Yan Tu
      • Qiyu Diao
      • Kai Cui

    • PubMed: 41933424
    • DOI: 10.1186/s40104-026-01371-5

    5 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Diarrhea Incidence
    • Improved Growth Performance
    • Reduced Inflammation
    • Increased Antioxidant Capacity

    • Low evidence
• April 5

  • Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review.

    • 2026-04-05
    • Review
    • Cureus 18(4)
    • • Pooja Singnale
      • Debasis Sasmal
      • Surya Goud S Chukkala
      • Monica Chilumula
      • Raghavendra Pandurangi
      • Soibam Peter Singh
      • Mahesh Kumar Mummadi
      • Ramesh Gondru

    • PubMed: 42099351
    • DOI: 10.7759/cureus.106497

    5 Insights on

    • Improved Insulin Sensitivity
    • Reduced Inflammatory Markers
    • Improved Blood Lipid Profile
    • Improved LH/FSHormonal Balance
    • Improved Ovarian Morphology

    • Low evidence
• April 6

  • The probiotic bacteria and their encapsulated forms as food components: Survival, effects and quality.

    • 2026-04-06
    • Review
    • AIMS microbiology 12(1)
    • • Elena Nikitina
      • Dmitrii Khrundin

    • PubMed: 41938781
    • DOI: 10.3934/microbiol.2026001

    4 Insights on

    • Improved Gastrointestinal Health
    • Improved Immune Function
    • Improved Functional Properties of Food
    • Improved Allergic Symptoms

    • Low evidence

  • Antioxidant Potential of Probiotics and Postbiotics Derived from Lactic Acid Bacteria and Their Impact on Foods.

    • 2026-04-06
    • Review
    • Foods (Basel, Switzerland) 15(7)
    • • Radoslav Abrashev
      • Ekaterina Krumova
      • Nikoleta Atanasova
      • Lili Dobreva
      • Maria Angelova
      • Svetla Danova

    • PubMed: 41976547
    • DOI: 10.3390/foods15071253

    3 Insights on

    • Increased Antioxidant Activity
    • Reduced Oxidative Stress
    • Improved Oxidative Stress Tolerance

    • Low evidence
• April 7

  • Vonoprazan-Amoxicillin Dual Therapy with or Without Saccharomyces boulardii Supplementation as a Rescue Regimen for Helicobacter pylori Infection.

    • 2026-04-07
    • Clinical Trial · n = 190
    • Infection and drug resistance 19
    • • Ding-Ni Qu
      • Ze-Xuan Ji
      • Jun-Qi Zhang
      • Xiao-Yong Wang

    • PubMed: 41971394
    • DOI: 10.2147/idr.s594118

    2 Insights on

    • Improved H Pylori Eradication Rates
    • Reduced Adverse Event

    • High evidence

  • Effects of Tart Cherry Juice Supplementation on Recovery from Exercise-Induced Muscle Damage in Athletes: A Systematic Review and Meta-Analysis.

    • 2026-04-07
    • Systematic Review
    • Sports medicine - open 12(1)
    • • Wael Daab
      • Mohamed Amine Bouzid
      • George P Nassis
      • Ashokan Arumugam
      • Achraf Ammar
      • Haris Pojskić
      • Abd-Elbasset Abaïdia

    • PubMed: 41945263
    • DOI: 10.1186/s40798-026-00993-3

    1 Insight on

    • Improved Muscle Strength

    • High evidence

  • Alcohol-Induced Acute Liver Disease in Mice: A Comparison of the Preventive Effects of Fermented Milk from Lactobacillus delbrueckii Subsp. bulgaricus or Lacticaseibacillus casei.

    • 2026-04-07
    • Foods (Basel, Switzerland) 15(7)
    • • Mingzhen Liu
      • Weimei Kong
      • Tao Zhang
      • Zhen Wu
      • Xiaoqun Zeng
      • Yuxing Guo
      • Daodong Pan

    • PubMed: 41976554
    • DOI: 10.3390/foods15071260

    4 Insights on

    • Improved Gut Microbiota Composition
    • Reduced Liver Inflammation
    • Reduced Alcohol-Induced Liver Injury
    • Reduced Alcohol-Induced Liver Inflammation

    • Low evidence

  • Investigation of the Effects of Postbiotics Obtained from Pediococcus acidilactici on Specific Biomarker Expressions in Intestinal Tissue.

    • 2026-04-07
    • n = 78
    • Foods (Basel, Switzerland) 15(7)
    • • Ismail Demircioğlu
      • Muhammet Bahaeddin Dörtbudak
      • Funda Aksünger Karaavci
      • Mehmet Emin Aydemir
      • Muhammed Demircioğlu
      • Aydın Genç
      • Ayşegül Demircioğlu
      • Güven Güngör
      • Alessandro Di Cerbo

    • PubMed: 41976561
    • DOI: 10.3390/foods15071267

    2 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Intestinal Histological Damage

    • Low evidence
• April 8

  • Effects of sodium bicarbonate, cholecalciferol, and protein supplementation interventions on muscle mass and metabolic disturbances in patients with chronic kidney disease: a systematic review and network meta-analysis.

    • 2026-04-08
    • Systematic Review · n = 879
    • Frontiers in nutrition 13
    • • Shuilian Leng
      • Meijun Wu
      • Jingchun Yao
      • Xiaojuan Jiang

    • PubMed: 42027563
    • DOI: 10.3389/fnut.2026.1698991

    1 Insight on

    • Increased Muscle Mass

    • High evidence

  • Comprehensive evaluation of the efficacy and safety of different vitamin D combination regimens based on indirect comparisons for children with rickets: a network meta-analysis.

    • 2026-04-08
    • Systematic Review · n = 867
    • Frontiers in nutrition 13
    • • Yunfeng Cao
      • Yan Zheng
      • Yaling Chen
      • Qihua Chen
      • Xinbin Xia
      • Ziyi Yuan
      • Honghui Li

    • PubMed: 42027572
    • DOI: 10.3389/fnut.2026.1785775

    4 Insights on

    • Increased Serum Albumin Levels
    • Reduced Bone-Specific Alkaline Phosphatase Level
    • Increased Serum Calcium Level
    • Increased Phosphate Level

    • High evidence

  • A Pilot Randomized, Controlled Trial of Nighttime Peanut Butter Supplementation in Firefighters: Blood Pressure and Body Composition Outcomes.

    • 2026-04-08
    • RCT · n = 40
    • Diseases (Basel, Switzerland) 14(4)
    • • Austin A Kohler
      • David H Shuler
      • Leke O Adeleye
      • Andrew R Moore
      • Nicole Peritore
      • A Maleah Winkler

    • PubMed: 42041627
    • DOI: 10.3390/diseases14040135

    5 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Systolic Blood Pressure
    • Reduced Body Fat Percentage
    • Reduced Body Fat Mass
    • Increased Lean Body Mass

    • High evidence

  • The role of nutrition and multimodal lifestyle interventions in Alzheimer's prevention and management: a mini-review.

    • 2026-04-08
    • Review
    • Frontiers in nutrition 13
    • • Hailong Zhang
      • Chenyang Liu
      • Xingxing Yuan
      • Hongna Yin

    • PubMed: 42027570
    • DOI: 10.3389/fnut.2026.1818913

    2 Insights on

    • Reduced Inflammation
    • Improved Memory Function

    • Low evidence

  • A full-spectrum aqueous extract of black cardamom (Amomum subulatum) improves focus/alertness and executive function: a randomized, double-blinded, placebo- and active-controlled, comparative study in healthy working-class participants.

    • 2026-04-08
    • Clinical Trial
    • Frontiers in neuroscience 20
    • • Jestin V Thomas
      • M E Mohan
      • Syam S Das
      • Nithyanandam Allimuthu
      • Sheena Devasia
      • P A Aneesa
      • Krishnakumar Illathu Madhavamenon
      • Baby Chakrapani Pulikkaparambil Sasidharan

    • PubMed: 42027681
    • DOI: 10.3389/fnins.2026.1786880

    1 Insight on

    • Improved Cognitive Function

    • High evidence
• April 9

  • Vitamin K as an Endocrine Modulator: Mechanistic Links to Glucose Metabolism and Beyond.

    • 2026-04-09
    • Review
    • Nutrients 18(8)
    • • Wojciech Matuszewski
      • Mikołaj Madeksza
      • Michał Szklarz
      • Aleksandra Rutkiewicz
      • Joanna Rutkowska
      • Joanna Maria Harazny

    • PubMed: 42074997
    • DOI: 10.3390/nu18081183

    3 Insights on

    • Improved Glucose Metabolism
    • Increased Bone Mineral Density
    • Reduced Risk of Type 2 Diabetes

    • Moderate evidence
    • Rigorous Journal
• April 10

  • Impact of Timing of Premedication on Mucosal Visibility During Endoscopy: A Randomized Controlled Trial.

    • 2026-04-10
    • RCT · n = 1,200
    • Journal of gastroenterology and hepatology 41(6)
    • • Zaheer Nabi
      • Preethi Sudha Dasireddy
      • Mahiboob Sayyed
      • Praveen Reddy
      • Rajesh Goud
      • Hardik Rughwani
      • Aniruddha Pratap Singh
      • Pradev Inavolu
      • Palle Manohar Reddy
      • Jahangeer Basha
      • Rajesh Gupta
      • Manu Tandan
      • D Nageshwar Reddy

    • PubMed: 41960652
    • DOI: 10.1111/jgh.70392

    3 Insights on

    • Improved Gastric Mucosal Visibility
    • Reduced Gastric Mucosal Visibility Score
    • Increased Detection of Gastric Lesion

    • High evidence
    • Large Human Trial
• April 11

  • Fish consumption and brain structure: a comprehensive systematic review of observational studies.

    • 2026-04-11
    • Systematic Review · n = 24
    • Aging clinical and experimental research 38(1)
    • • Justyna Godos
      • Giuseppe Caruso
      • Agnieszka Micek
      • Alberto Dolci
      • Zoltan Ungvari
      • Andrea Lehoczki
      • Lisandra Leon
      • Evelyn Frias-Toral
      • Andrea Di Mauro
      • Mario Siervo
      • Michelino Di Rosa
      • Giuseppe Grosso

    • PubMed: 41963547
    • DOI: 10.1007/s40520-026-03363-x

    5 Insights on

    • Reduced White Matter Hyperintensity Severity
    • Reduced Cerebral Microbleed
    • Preserved Brain Volume
    • Preserved Cortical Thickness
    • Slowed Progression of White Matter Hyperintensities

    • High evidence
• April 13

  • Effect of intravenous vitamin C administration on chemotherapy-induced adverse events in patients with nasopharyngeal cancer.

    • 2026-04-13
    • RCT
    • PloS one 21(4)
    • • Peesit Leelasawatsuk
      • Pasawat Supanimitjaroenporn
      • Nattida Rodsom
      • Theepat Wongkittithaworn
      • Manupol Tangthongkum

    • PubMed: 41973719
    • DOI: 10.1371/journal.pone.0346818

    1 Insight on

    • Increased Platelet Count

    • High evidence

  • The Role of Honey in Dental Caries Prevention: A Narrative Review.

    • 2026-04-13
    • Review
    • Cureus 18(4)
    • • Pierluigi Valente
      • Lapo Sbrenna
      • Andrea Mascolo
      • Andrea Sbrenna
      • Francesco Valente

    • PubMed: 42137682
    • DOI: 10.7759/cureus.106948

    2 Insights on

    • Reduced Plaque Accumulation
    • Improved Gingival Health

    • Low evidence

  • Vitamin D supplementation in infertile men: a systematic review and meta-analysis of effects on semen quality and endocrine function.

    • 2026-04-13
    • Meta-Analysis
    • PeerJ 14
    • • Guoqing Zhang
      • Giribabu Nelli
      • See Ziau Hoe
      • Mukhri Hamdan

    • PubMed: 42004696
    • DOI: 10.7717/peerj.21002

    6 Insights on

    • Improved Semen Volume
    • Improved Sperm Concentration
    • Improved Progressive Motility
    • Improved Testosterone Level
    • Improved Clinical Pregnancy
    • Improved Live Birth Rate

    • High evidence
    • Rigorous Journal
• April 14

  • The AhR-TLR4 axis in non-IgE-mediated Cow's milk allergy: a systematic review with integrated multi-omics corroboration.

    • 2026-04-14
    • Review
    • Frontiers in allergy 7
    • • Wei Kong
      • Bin Wu
      • Ying Huang
      • Haiying Liu
      • Congfu Huang

    • PubMed: 42058623
    • DOI: 10.3389/falgy.2026.1789143

    1 Insight on

    • Resolved Cow Milk Allergy Symptoms

    • Low evidence

  • Effects of race distance and probiotics intervention on kidney, muscle, and gut injury and inflammation biomarker responses during running.

    • 2026-04-14
    • RCT · n = 34
    • Journal of the International Society of Sports Nutrition 23(1)
    • • Erik Hansson
      • Bethany Skinner
      • Tiziana Falcone
      • Amitava Halder
      • Rebekah A I Lucas

    • PubMed: 41981959
    • DOI: 10.1080/15502783.2026.2651356

    2 Insights on

    • Reduced Gut Inflammation
    • Reduced Kidney Injury

    • High evidence

  • The role of Traditional Chinese Medicine in the management of liver disease: targeting gut microbiome.

    • 2026-04-14
    • Review
    • Chinese medicine 21(1)
    • • Yifan Zhang
      • Hongkun Li
      • Fei Yu
      • Mengmeng Gao
      • Yang Wang
      • Siyu Xin
      • Jiating Yang
      • Zhiwei Wang
      • Lujie Xiang
      • Qingjing Ru
      • Na Jiang

    • PubMed: 41981689
    • DOI: 10.1186/s13020-026-01395-z

    2 Insights on

    • Modulated Gut Microbiota
    • Improved Liver Health

    • Low evidence

  • Lactobacillus combination alleviates dextran sulfate sodium-induced colitis in Wuzhishan minipigs.

    • 2026-04-14
    • Food & function 17(7)
    • • Xiaozhe Wang
      • Xiangyu Ma
      • Xin Zhang
      • Yang He
      • Yinfeng Chen
      • Qingyao Fu
      • Ying Yang
      • Xiaomin Yin
      • Zhenlong Wu

    • PubMed: 41860415
    • DOI: 10.1039/d4fo04728a

    4 Insights on

    • Improved Gut Microbiota Composition
    • Improved Intestinal Barrier Function
    • Reduced Colitis Severity
    • Reduced Inflammation

    • Low evidence
    • Rigorous Journal
    • Animal Study
• April 15

  • When probiotics guidelines differ: a practical guide for clinicians and researchers.

    • 2026-04-15
    • Review
    • Gut microbes 18(1)
    • • Geoffrey A Preidis
      • Hania Szajewska
      • Marla Cunningham
      • Howard Bauchner
      • Daniel J Merenstein

    • PubMed: 41986915
    • DOI: 10.1080/19490976.2026.2657049

    2 Insights on

    • Improved Gastrointestinal Health
    • Improved Gastrointestinal Symptoms

    • Low evidence

  • Efficacy and mechanisms of Gynostemma pentaphyllum as a medicine food homology herb in glycemic control: a meta-analysis with review.

    • 2026-04-15
    • Systematic Review · n = 584
    • Frontiers in pharmacology 17
    • • Ruoshi Wang
      • Yuqing Wang
      • Yanfei Mo
      • Heng Zhang
      • Gaoxiang Ma

    • PubMed: 42064816
    • DOI: 10.3389/fphar.2026.1731723

    3 Insights on

    • Improved Fasting Plasma Glucose
    • Reduced Postprandial Glucose
    • Reduced Glycated Hemoglobin

    • High evidence

  • Protective Effect of Intracellular Compounds of Lactobacillus plantarum on Goat Sperm Quality During Cryopreservation.

    • 2026-04-15
    • Veterinary medicine and science 12(3)
    • • Farshad Ariyan
      • Amjad Farzinpour
      • Abbas Farshad
      • Aram Sharifi

    • PubMed: 41983503
    • DOI: 10.1002/vms3.70850

    1 Insight on

    • Improved Semen Quality

    • Low evidence
    • Animal Study

  • Spirulina as a sustainable functional ingredient: nutrient density, bioactives, and food applications.

    • 2026-04-15
    • Review
    • Frontiers in nutrition 13
    • • Marwa Ezz El-Din Ibrahim
      • Selinay Demirel
      • Seydi Yıkmış
      • Nazan Tokatlı Demirok
      • Maisa Bushra Omer Ahmed
      • Amin K Amin

    • PubMed: 42063958
    • DOI: 10.3389/fnut.2026.1810841

    5 Insights on

    • Improved Immune Function
    • Reduced Inflammation
    • Reduced Oxidative Stress
    • Improved Blood Lipid Profile
    • Improved Glycemia

    • Low evidence

  • Effects of a single dose of L-histidine on mental fatigue and vigor in participants with high fatigue levels: a randomized controlled trial.

    • 2026-04-15
    • RCT
    • Scientific reports 16(1)
    • • Masatsugu Shimomasuda
      • Haruna Fujiyoshi
      • Yu Kajiyama
      • Mayuka Kanda
      • Kenta Kajiwara
      • Kenji Nagao
      • Akira Abe
      • Shigekazu Kurihara
      • Hiroyuki Kato
      • Hidehiro Nakamura

    • PubMed: 41986440
    • DOI: 10.1038/s41598-026-48060-x

    9 Insights on

    • Reduced Confusion and Bewilderment
    • Reduced Mood Disturbance
    • Reduced Depression
    • Improved Vigor
    • Reduced Fatigue-Inertia
    • Reduced Confusion-Bewilderment T-Score
    • Reduced Depression-Dejection T-score
    • Improved Mental Task Performance
    • Improved Vigor-Activity

    • High evidence
    • Rigorous Journal
• April 16

  • Interactions Between Blood Nutritional Biomarkers and Apolipoprotein E ε4 in the Progression of Mild Cognitive Impairment in Alzheimer's Disease.

    • 2026-04-16
    • Systematic Review
    • Nutrients 18(8)
    • • Rasheedat Lawal
      • Sanjay Kumar
      • Rosemary Chigevenga
      • Shelly Coe

    • PubMed: 42075076
    • DOI: 10.3390/nu18081263

    1 Insight on

    • Improved Cognitive Function

    • High evidence
    • Rigorous Journal
• April 17

  • First insights into the intestinal microbiota of the endangered Angler Saddleback pig.

    • 2026-04-17
    • Observational
    • PloS one 21(4)
    • • Stéphanie Céline Hornburg
      • Marvin Suhr
      • Corinna Bang
      • Dirk Hinrichs
      • Stefanie Klingel
      • Georg Thaller
      • Anna Olschewsky

    • PubMed: 41996348
    • DOI: 10.1371/journal.pone.0345650

    1 Insight on

    • Improved Gut Microbiota Composition

    • Low evidence
    • Animal Study

  • Effects of Resistance Exercise and Whey Protein Supplementation on Irisin Levels in Patients with MASLD Under a Calorie-Restricted Diet.

    • 2026-04-17
    • RCT
    • Nutrients 18(8)
    • • Feng-Rui Zhang
      • Chae-Been Kim
      • Dohyun Ahn
      • Jinwoo Sung
      • Ju-Hwan Oh
      • Hae-Ri Heo
      • Eun-Ah Jo
      • Hong-Soo Kim
      • Jung-Jun Park

    • PubMed: 42075090
    • DOI: 10.3390/nu18081272

    4 Insights on

    • Increased Muscle Mass
    • Reduced Hepatic Steatosis
    • Increased Irisin Level
    • Reduced Hepatic Fat

    • High evidence
    • Rigorous Journal

  • Lactobacillus plantarum as a Novel Modulator of Immune and Behavioral Recovery in Substance Use Disorders: A Hypothesis.

    • 2026-04-17
    • Current drug research reviews 18
    • • Jonaid Ahmad Malik

    • PubMed: 42003076
    • DOI: 10.2174/0125899775442579260409073358

    6 Insights on

    • Reduced Neuroinflammation
    • Improved Behavioral Health
    • Improved Immune Tolerance
    • Improved Behavioral Recovery
    • Improved Gut Microbial Balance
    • Reduced Glial Cell Activation

    • Low evidence

  • The Role of Dietary Supplements in the Treatment of Endometriosis: A Critical Review.

    • 2026-04-17
    • Review
    • Nutrients 18(8)
    • • Mariusz Wójtowicz
      • Paweł Małek
      • Magdalena Olszanecka-Glinianowicz

    • PubMed: 42075089
    • DOI: 10.3390/nu18081274

    1 Insight on

    • Reduced Endometriotic Lesion Size

    • Moderate evidence
    • Rigorous Journal
• April 18

  • Phytochemical and Fungal Bioactive Compounds in the "Brain Health Triad": A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy.

    • 2026-04-18
    • Review
    • International journal of molecular sciences 27(8)
    • • Giovanni Luca Cipriano
      • Ivana Raffaele
      • Alessia Floramo
      • Veronica Argento
      • Maria Francesca Astorino
      • Maria Lui
      • Marco Calabrò
      • Ivan Anchesi

    • PubMed: 42074246
    • DOI: 10.3390/ijms27083607

    3 Insights on

    • Increased Brain-derived Neurotrophic Factor Level
    • Increased Nerve Growth Factor Level
    • Enhanced Synaptic Plasticity

    • Moderate evidence
    • Rigorous Journal
• April 20

  • Different doses of vitamin A supplementation as adjuvant treatment for pneumonia in children: a network meta-analysis of randomized controlled trials.

    • 2026-04-20
    • Meta-Analysis · n = 3,116
    • European journal of pediatrics 185(5)
    • • Cong-Jun Zhou
      • Zhi-Cheng Su
      • Song Li
      • Yu Jin
      • Hai-Chang Chen
      • Zi-Jun Li
      • Yun-He Tian
      • Yi-Die Lin
      • Tian-Ming Yan
      • Feng-Yi Wu
      • Zhen-Cen Liu
      • Ya-Dan Liu
      • Wei Zhang
      • Xin-Yi Lei
      • Man-Di Li
      • Jing Yang
      • Yi-Neng Mao
      • Cai-Rong Zhu

    • PubMed: 42008030
    • DOI: 10.1007/s00431-026-06947-x

    3 Insights on

    • Reduced Fever Duration
    • Improved Clinical Outcomes
    • Reduced Cough Duration

    • High evidence

  • Comparative Effectiveness of Pharmacological and Non-Pharmacological Interventions for Nausea and Vomiting in Pregnancy: A Systematic Review and Network Meta-Analysis.

    • 2026-04-20
    • Meta-Analysis · n = 3,017
    • Nutrients 18(8)
    • • Lőrinc Frivaldszky
      • Mahmoud Obeidat
      • Péter Hegyi
      • Csongor Kárpáti
      • Zoltán Kobza
      • Nándor Ács
      • Ferenc Bánhidy
      • Gergely Agócs
      • Boglárka Lilla Szentes
      • Márton Keszthelyi

    • PubMed: 42075106
    • DOI: 10.3390/nu18081293

    1 Insight on

    • Reduced Nausea and Vomiting in Pregnancy Symptoms

    • High evidence
    • Rigorous Journal
• April 21

  • Individual responses to pomegranate juice on recovery from exercise-induced muscle damage in collegiate male volleyball players.

    • 2026-04-21
    • RCT
    • Journal of the International Society of Sports Nutrition 23(1)
    • • Gholamreza Rezaei
      • Mohammad Hemmatinafar
      • Mark E T Willems
      • Dena Mastouri
      • Babak Imanian
      • Rasoul Rezaei

    • PubMed: 42015544
    • DOI: 10.1080/15502783.2026.2642149

    9 Insights on

    • Improved Handgrip Strength
    • Improved Vertical Jump Height
    • Reduced Delayed-Onset Muscle Soreness
    • Improved Flexibility
    • Improved Maximal Voluntary Isometric Contraction
    • Improved Medicine-Ball Throw
    • Improved Wall-Squat Performance
    • Improved Knee Extensor Peak Torque
    • Improved Knee Flexor Peak Torque

    • High evidence

  • Genetic engineering of gut commensals: heterologous protein expression in Bifidobacterium animalis subsp. lactis CECT8145.

    • 2026-04-21
    • Current research in microbial sciences 10
    • • Alba Arévalo-Lalanne
      • Paola Corbín-Agustí
      • Daniel Ramón
      • Javier Buceta
      • Juli Peretó
      • Marta Tortajada

    • PubMed: 42005543
    • DOI: 10.1016/j.crmicr.2026.100591

    2 Insights on

    • Improved Metabolic Health
    • Improved Healthy Aging

    • Low evidence
• April 22

  • From Plate to Mind: Scientific Perspectives on Foods That May Influence Anxiety and Depression.

    • 2026-04-22
    • Meta-Analysis
    • Nutrients 18(9)
    • • Antoniya Hachmeriyan
      • Gabriela Panayotova
      • Hristiyana Todorova

    • PubMed: 42123920
    • DOI: 10.3390/nu18091318

    1 Insight on

    • Reduced Depression Symptoms

    • High evidence
    • Rigorous Journal

  • Efficacy and safety of dietary supplements for the treatment of ulcerative colitis, a network meta-analysis.

    • 2026-04-22
    • Systematic Review · n = 491
    • Frontiers in medicine 13
    • • Rong Xu
      • Zhiyu Zhang
      • Ying Li
      • Zhijiu Wu

    • PubMed: 42100281
    • DOI: 10.3389/fmed.2026.1816535

    3 Insights on

    • Reduced Clinical Activity Index
    • Reduced Mayo Score
    • Improved Inflammatory Bowelayed Inflammatory Bowel Disease Questionnaire Score

    • High evidence

  • Effects of Allium fistulosum L. (Green Onion) Root and Avena sativa L. (Oat) Mixtures (WCO31) on the Height of Children: A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

    • 2026-04-22
    • RCT · n = 150
    • Nutrients 18(9)
    • • You-Jin Kim
      • Do-Yeon Kim
      • Seong-In Cheong
      • Hye Jeong Yang
      • Min Jung Kim
      • Hyun-Jun Jang
      • Myung-Sunny Kim
      • Dai Ja Jang
      • Nu-Ri Ha
      • Seul-Ki Kim
      • Min-Hwan Bae
      • Jong-Cheon Joo
      • Soo-Jung Park

    • PubMed: 42123928
    • DOI: 10.3390/nu18091326

    5 Insights on

    • Increased Growth Rate
    • Increased Height
    • Improved Height-for-Age Z-Score
    • Improved Growth Rate Standard Deviation Score
    • Improved Height Standard Deviation Score

    • High evidence
    • Large Human Trial
    • Rigorous Journal

  • Bifidobacterium bifidum G9-1 Intake Improves Gastrointestinal Symptoms in Type 2 Diabetes Mellitus: An Open-Label, Randomized Controlled Trial (Binary STAR Study).

    • 2026-04-22
    • RCT · n = 100
    • Diabetes, obesity & metabolism 28(7)
    • • Genki Kobayashi
      • Yoshitaka Hashimoto
      • Tomoyuki Matsuyama
      • Noriyuki Kitagawa
      • Saori Majima
      • Takafumi Senmaru
      • Emi Ushigome
      • Hiroshi Okada
      • Naoko Nakanishi
      • Masahide Hamaguchi
      • Michiaki Fukui

    • PubMed: 42017290
    • DOI: 10.1111/dom.70805

    5 Insights on

    • Increased Short-Chain Fatty Acid Levels
    • Reduced Diarrhea Severity
    • Reduced Severity of Gastrointestinal Disorders
    • Reduced Constipation Severity
    • Increased Phocaeicola Abundance

    • High evidence
    • Large Human Trial
• April 23

  • Effects of Combined Caffeine and Rhodiola rosea Supplementation on Repeated Aerial Duel Performance and Neck Neuromuscular Function in Soccer Players.

    • 2026-04-23
    • RCT
    • Nutrients 18(9)
    • • Yue Dou
      • Ziyi Feng
      • Hengquan Xu
      • Hexin Ma
      • Yuewei Jiang
      • Xinping Lyu
      • Bolin Han
      • Shuning Liu
      • Chang Liu
      • Dingmeng Ren

    • PubMed: 42123940
    • DOI: 10.3390/nu18091339

    7 Insights on

    • Reduced Rating of Perceived Exertion
    • Improved Countermovement Jump Height
    • Improved Early Take-off Impulse
    • Improved Repeated Heading Contact Height
    • Improved Ball Exit Velocity
    • Improved Heading Duel Success Rate
    • Improved Neck Maximal Voluntary Isometric Contraction

    • High evidence
    • Rigorous Journal

  • Vitamin D Receptor Polymorphisms and the Effect of Vitamin D Supplementation on Diabetes Risk Among Adults With Prediabetes.

    • 2026-04-23
    • RCT · n = 2,098
    • JAMA network open 9(4)
    • • Bess Dawson-Hughes
      • Gordon S Huggins
      • Jason Nelson
      • Ellen Vickery
      • Sarah N Powers
      • Anastassios G Pittas

    • PubMed: 42024385
    • DOI: 10.1001/jamanetworkopen.2026.7332

    1 Insight on

    • Reduced Risk of Diabetes

    • High evidence
    • Large Human Trial
    • Rigorous Journal

  • The Lack of a COPII Cargo Receptor Erv14 Impacts Physiological Functions of the Vacuole in Saccharomyces cerevisiae.

    • 2026-04-23
    • Traffic (Copenhagen, Denmark) 27(2)
    • • Paul Rosas-Santiago
      • Jorge Luis Ruiz Salas
      • Elizabeth Cordoba
      • Francisco Vera-López Portillo
      • Prisciluis Caheri Salas-Navarrete
      • Jaime Arturo Pimentel Cabrera
      • Alfredo Martínez
      • Nayeli Imelda Roldan Ramírez
      • Dieter Chavelas Hernández
      • Andrés Saralegui-Amaro
      • Martha Calahorra
      • Hana Sychrová
      • Olga Zimmermannová

    • PubMed: 42026727
    • DOI: 10.1111/tra.70035

    2 Insights on

    • Improved Stress Tolerance
    • Impaired Vacuolar Function

    • Low evidence

  • Effects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial.

    • 2026-04-23
    • RCT · n = 40
    • PloS one 21(4)
    • • Jonathan Sinclair
      • Benjamin Sant
      • XuanYi Du
      • Gareth Shadwell
      • Stephanie Dillon
      • Bobbie Butters
      • Lindsay Bottoms

    • PubMed: 42024666
    • DOI: 10.1371/journal.pone.0344538

    7 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Blood Pressure
    • Improved Psychological Well-being
    • Reduced Resting Heart Rate
    • Improved Sleep Efficacy
    • Reduced Anthropometric Index
    • Reduced Hematological Index

    • High evidence

  • The Assessment of Multidimensional Clinical, Biological and Patient-Reported Outcomes to Evaluate the Efficacy of Add-On Lactobacillus rhamnosus GG Supplementation in Mild Ulcerative Colitis: A Randomized Pilot Trial.

    • 2026-04-23
    • RCT
    • Nutrients 18(9)
    • • Paola Maragno
      • Chiara Amoroso
      • Simone Conforti
      • Marco Michelon
      • Ivanna Honcharyuk
      • Clorinda Ciafardini
      • Daniele Noviello
      • Francesco Strati
      • Flavio Caprioli
      • Federica Facciotti
      • Maurizio Vecchi

    • PubMed: 42123931
    • DOI: 10.3390/nu18091329

    5 Insights on

    • Reduced Faecal Calprotectin
    • Improved Health-related Quality of Life
    • Improved Clinical Activity
    • Increased Clinical Response Proportion
    • Increased IL-22-Producing CD4+ T Cell Count

    • High evidence
    • Rigorous Journal

  • Calorie-restricted oat diet is associated with zonulin and short-chain fatty acid response in metabolic syndrome: a randomized controlled trial.

    • 2026-04-23
    • RCT
    • Gut microbes 18(1)
    • • Linda Klümpen
      • Aakash Mantri
      • Anna Donkers
      • Waldemar Seel
      • Birgit Stoffel-Wagner
      • Martin Coenen
      • Matthias Schmid
      • Leonie Weinhold
      • Fabian Grein
      • Patrick Newels
      • Janis Bedarf
      • Ullrich Wüllner
      • Peter Stehle
      • Marie-Christine Simon

    • PubMed: 42026801
    • DOI: 10.1080/19490976.2026.2662687

    2 Insights on

    • Increased Fecal Butyrate Levels
    • Reduced Zonulin Level

    • High evidence
• April 24

  • Trace Elements and Depressive Symptoms in Coronary Artery Disease: A Systematic Review of Sparse and Predominantly Indirect Evidence.

    • 2026-04-24
    • Systematic Review
    • International journal of molecular sciences 27(9)
    • • Jakub Marek Baran
      • Zuzanna Waszak
      • Joanna Jarzębska
      • Damian Grusiecki
      • Maja Śmigielska
      • Wacław Kochman
      • Ewelina A Dziedzic

    • PubMed: 42123390
    • DOI: 10.3390/ijms27093805

    1 Insight on

    • Reduced Depression Symptoms

    • High evidence
    • Rigorous Journal

  • The protective effect of probiotics on intestinal mucosal injury and dysbiosis in infants with congenital heart disease undergoing cardiopulmonary bypass.

    • 2026-04-24
    • RCT
    • Frontiers in immunology 17
    • • Zhixuan Zhang
      • Xiaoxu Liu
      • Zhaocong Yang
      • Lan Jiang
      • Chengbin Tang
      • Xuming Mo

    • PubMed: 42112337
    • DOI: 10.3389/fimmu.2026.1759934

    7 Insights on

    • Reduced Diarrhea Incidence
    • Reduced C-Reactive Protein Levels
    • Reduced Enteral Nutrition Initiation Time
    • Reduced Duration of Gastrointestinal Decompression
    • Reduced IFABP Level
    • Reduced Diamine Oxidase Level
    • Reduced D-Lactate Level

    • High evidence

  • A randomized controlled trial of L-taurine for fatigue in decompensated cirrhosis.

    • 2026-04-24
    • RCT · n = 161
    • Hepatology communications 10(5)
    • • Swarup Sasidharan
      • Cyriac Abby Philips
      • Ajit Tharakan
      • Rizwan Ahamed
      • Tharun Tom Oommen
      • John Menachery
      • Rosh Varghese
      • Philip Augustine

    • PubMed: 42043864
    • DOI: 10.1097/hc9.0000000000000938

    3 Insights on

    • Reduced Fatigue
    • Adverse Events
    • Reduced Fatigue Severity

    • High evidence
    • Large Human Trial

  • Comparative Evaluation of Vitamin C and Injectable Platelet-rich Fibrin in the Management of Thin Gingival Phenotype: A Split-mouth Randomized Clinical Trial.

    • 2026-04-24
    • RCT
    • The journal of contemporary dental practice 27(2)
    • • Noha M Abdelhay
      • Manar T Elzanaty
      • Riham O Ibrahim

    • PubMed: 42145166
    • DOI: 10.5005/jp-journals-10024-4022

    5 Insights on

    • Reduced Gingival Index
    • Reduced Plaque Index
    • Reduced Pocket Depth
    • Increased Gingival Thickness
    • Increased Keratinized Tissue Width

    • High evidence
• April 27

  • Efficacy and Safety of Limosilactobacillus reuteri DSM 17938 in Infantile Colic: A Narrative Review From Pathogenesis to Clinical Practice.

    • 2026-04-27
    • Review
    • Cureus 18(4)
    • • Kimberly Carvajal Méndez
      • Ana Gabriela Álvarez Barrientos
      • Freddy Gutiérrez Rivera
      • Daniel Aragón Leiva
      • Dennis Ulate Fuentes

    • PubMed: 42211616
    • DOI: 10.7759/cureus.107824

    1 Insight on

    • Reduced Crying Time

    • Low evidence

  • Triphala as a Topical Agent in Gynaecological Disorders: A Comprehensive Review of Its Pharmacological Actions and Applications.

    • 2026-04-27
    • Review
    • Cureus 18(4)
    • • Anita
      • Latika Kundra
      • Poonam Verma
      • Nidhi Tahlan

    • PubMed: 42220723
    • DOI: 10.7759/cureus.107796

    1 Insight on

    • Increased Vaginal Lactobacilli Levels

    • Low evidence

  • Curcumin Supplementation Reduces Inflammation, Neutrophil-to-Lymphocyte Ratio (NLR), and Antioxidant Status in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial.

    • 2026-04-27
    • RCT · n = 114
    • International journal of molecular sciences 27(9)
    • • Metha Yaikwawong
      • Khanittha Kamdee
      • Somlak Chuengsamarn

    • PubMed: 42123439
    • DOI: 10.3390/ijms27093854

    8 Insights on

    • Reduced Pro-inflammatory Cytokine Levels
    • Reduced Hemoglobin A1c
    • Improved Total Antioxidant Status
    • Improved Insulin Resistance
    • Improved Fasting Plasma Glucose
    • Reduced High-Sensitivity C-Reactive Protein Level
    • Reduced Malondialdehyde Level
    • Reduced Neutrophil-to-Lymphocyte Ratio

    • High evidence
    • Large Human Trial
    • Rigorous Journal
• April 28

  • The Efficacy of Probiotics in Treating Upper Respiratory Tract Infections, Allergic Rhinitis, and Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis.

    • 2026-04-28
    • Review
    • Microorganisms 14(5)
    • • Arezki Azzi
      • Assaf S Alotaibi
      • Muath S Alamri
      • Mohammed A Al-Dosari
      • Faris M Al Murdhi
      • Mohammed N Alatyani
      • Saad M Alnojaim
      • Mohammed A Alrufayyiq
      • Mohammed O Altowaijri

    • PubMed: 42197372
    • DOI: 10.3390/microorganisms14050986

    2 Insights on

    • Reduced Antibiotic Use
    • Reduced Symptom Duration

    • Low evidence

  • The Effects of Carnosine on Cognitive Function and Mental Health-A Systematic Review and Meta-Analysis.

    • 2026-04-28
    • Meta-Analysis · n = 13
    • Nutrients 18(9)
    • • Yung-Fang Hsiao
      • Zhongqi Fan
      • Yueh-Yin Fan
      • Mei Chung

    • PubMed: 42123986
    • DOI: 10.3390/nu18091385

    4 Insights on

    • Improved Quality of Life
    • Improved Cognitive Function
    • Reduced Depression Symptoms
    • Improved MMSE Score

    • High evidence
    • Rigorous Journal

  • The effect of dietary nitrate on weight management: a systematic review and meta-analysis.

    • 2026-04-28
    • Meta-Analysis · n = 199
    • Frontiers in public health 14
    • • Wenjun Cai
      • Peng Wei
      • Fan Yang
      • Lin Shu
      • Yongyao Du
      • Huirong Feng
      • Jiaojiao Shi
      • Chao Kang
      • Xiaoli Peng

    • PubMed: 42130877
    • DOI: 10.3389/fpubh.2026.1798811

    6 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Body Mass Index
    • Reduced Systolic Blood Pressure
    • Reduced Body Weight
    • Reduced Triglyceride Levels
    • Reduced Blood Cholesterol

    • High evidence
• April 29

  • Clinical efficacy and patient-reported outcomes of coconut oil as adjunctive periodontitis treatment: triple-blinded pilot randomized trial.

    • 2026-04-29
    • RCT
    • BMC oral health 26(1)
    • • Simón Pardiñas López
      • Ismael Khouly
      • Fabiana Aellos
      • Karol Apaza Alccayhuaman
      • Silvia María Díaz Prado

    • PubMed: 42057009
    • DOI: 10.1186/s12903-026-08411-6

    8 Insights on

    • Improved Quality of Life
    • Reduced Probing Pocket Depth
    • Reduced Bleeding on Probing (BOP)
    • Improved Clinical Attachment
    • Reduced Plaque Index
    • Reduced Sulfur Compound Level
    • Reduced Mouth Dryness
    • Improved Breath Perception

    • High evidence

  • Randomized clinical trial comparing intra-articular injection of bone marrow aspirate clot and bone marrow aspirate concentrate in grade 3 and 4 knee osteoarthritis.

    • 2026-04-29
    • RCT
    • Stem cell research & therapy 17(1)
    • • José Fábio Lana
      • Luyddy Pires
      • Alex Macedo
      • Sérgio Mainine
      • Tomas Mosaner
      • Daniel de Moraes Ferreira Jorge
      • Gabriel Azzini
      • Lucas Furtado da Fonseca
      • Claudia Herrera Tambeli
      • Marco Antônio Percope de Andrade

    • PubMed: 42057095
    • DOI: 10.1186/s13287-026-05041-1

    1 Insight on

    • Improved Quality of Life

    • High evidence

  • Explore the Optimal Treatment Regimen Across Combinations of Variate Protein Sources and Exercise Modalities and Its Associated Factors in Older Adults: A Network Meta-Analysis and Meta-Regression of Randomized Controlled Trials.

    • 2026-04-29
    • Meta-Analysis · n = 980
    • Nutrients 18(9)
    • • Che-Li Lin
      • Shih-Wei Huang
      • Hung-Chou Chen
      • Mao-Hua Huang
      • Tsan-Hon Liou
      • Chun-De Liao

    • PubMed: 42124009
    • DOI: 10.3390/nu18091409

    6 Insights on

    • Improved Handgrip Strength
    • Increased Lean Mass
    • Improved Leg Strength
    • Improved Chair Rise Performance
    • Improved Timed Up and Go
    • Improved Mobility Score

    • High evidence
    • Rigorous Journal

  • Vitamin K Biochemistry and Pharmacokinetics: The Basis of Late Vitamin K Deficiency Intracranial Bleeding in Early Infancy.

    • 2026-04-29
    • Review
    • International journal of molecular sciences 27(9)
    • • Serafina Perrone
      • Virginia Beretta
      • Vincenzo Raitano
      • Liana Cerioni
      • Silvia Carloni

    • PubMed: 42123580
    • DOI: 10.3390/ijms27094000

    1 Insight on

    • Reduced Intracranial Hemorrhage

    • Moderate evidence
    • Rigorous Journal

  • Quantum theories of consciousness: a critical review of feasibility, philosophical sufficiency, and empirical testability.

    • 2026-04-29
    • Review
    • Frontiers in psychology 17
    • • Xun Ma
      • Aoping Wang

    • PubMed: 42137085
    • DOI: 10.3389/fpsyg.2026.1730965

    2 Insights on

    • Reduced Hemoglobin A1c
    • Reduced Fasting Blood Glucose Levels

    • Low evidence

  • Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels -A Narrative Review.

    • 2026-04-29
    • Review
    • Dermatology and therapy 16(6)
    • • Priscila Arbex
      • Edwin D Lephart

    • PubMed: 42056376
    • DOI: 10.1007/s13555-026-01731-z

    4 Insights on

    • Increased Skin Mucus Protein Levels
    • Improved Scalp Hair Health
    • Improved Nail Health
    • Improved Dermal Health Parameter

    • Low evidence
• April 30

  • Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials.

    • 2026-04-30
    • Review
    • Endocrinology and metabolism (Seoul, Korea) 41(2)
    • • Sung Hye Kong

    • PubMed: 42114835
    • DOI: 10.3803/enm.2026.2938

    3 Insights on

    • Reduced Fall Risk
    • Reduced Fracture Risk
    • Increased Fall Risk

    • Low evidence

  • Therapeutic Outcomes of Aloe vera Gel Compared with Triamcinolone Acetonide in Minor Aphthous Stomatitis.

    • 2026-04-30
    • RCT · n = 60
    • Nigerian journal of clinical practice 29(4)
    • • Bhavna
      • S Anand
      • D Jyoti
      • Shalini
      • J Lakshmi

    • PubMed: 42085084
    • DOI: 10.4103/njcp.njcp_767_25

    2 Insights on

    • Reduced Pain Severity
    • Improved Oral Mucositis Healing

    • High evidence

  • The Effect of β-Hydroxy-β-Methyl Butyrate (HMB) upon Acute Fed-State Muscle Protein Turnover in Older Men and Women: A Randomized Double-Blind Controlled Crossover Clinical Trial.

    • 2026-04-30
    • RCT · n = 24
    • Nutrients 18(9)
    • • Kenneth Smith
      • Kenneth Smith
      • Haitham Abdullah
      • Supreeth Rudrappa
      • Amanda Gates
      • Jonathan Lewis
      • Iskandar Idris
      • Joseph J Bass
      • Hannah Crossland
      • Daniel J Wilkinson
      • Min Tian
      • Deborah S Hustead
      • Geraldine E Baggs
      • Suzette L Pereira
      • Bethan E Phillips
      • Philip J Atherton

    • PubMed: 42124050
    • DOI: 10.3390/nu18091449

    1 Insight on

    • Increased Muscle Protein Synthesis

    • High evidence
    • Rigorous Journal
• Undated – 43 supplement studies

  • Insomnia: the gut microbiome connection, prospects for probiotic and postbiotic therapies, and future directions.

    • 2026-04
    • Review
    • Journal of advanced research 82
    • • Qiong Wu
      • Guangqi Gao
      • Lai-Yu Kwok
      • Huimin Lv
      • Zhihong Sun

    • PubMed: 40651630
    • DOI: 10.1016/j.jare.2025.07.005

    2 Insights on

    • Improved Sleep Quality
    • Improved Insomnia

    • Low evidence

  • High-dose Oral Vitamin C Supplementation and Acute Pain Control Following Laparoscopic Cholecystectomy: A Randomized Controlled Study.

    • 2026-04
    • RCT · n = 320
    • Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 41(2)
    • • Yoonyoung Choi
      • Tae Ho Hong

    • PubMed: 41042187
    • DOI: 10.1016/j.jopan.2025.06.008

    5 Insights on

    • Reduced Vomiting Frequency
    • Reduced Length of Hospital Stay
    • Reduced White Blood Cell Count
    • Reduced Postoperative Complications
    • Reduced Acute Pain

    • High evidence
    • Large Human Trial

  • Fibre manipulation to manage symptom severity and quality of life in patients with functional bowel disorders: A systematic review.

    • 2026-04
    • Systematic Review
    • Clinical nutrition ESPEN 72
    • • Rojina Raked
      • Mary Ibrahim
      • Jennifer Utter
      • Shannon Morley
      • Kate Mueller

    • PubMed: 41525871
    • DOI: 10.1016/j.clnesp.2025.102896

    1 Insight on

    • Improved Stool Consistency

    • High evidence

  • Does Chlorella Supplementation Improve Adiposity, Metabolic Dysfunction, and Oxidative Stress in Individuals With Excess Weight? A Systematic Review and Meta-Analysis.

    • 2026-04
    • Review · n = 717
    • Food science & nutrition 14(4)
    • • Ali Jafari
      • Helia Mardani
      • Mahsa Mahmoudinezhad
      • Mohammad Amin Karimi
      • Vali Musazadeh
      • Mohammad Sharifi

    • PubMed: 42027804
    • DOI: 10.1002/fsn3.71715

    5 Insights on

    • Improved Insulin Sensitivity
    • Reduced Body Mass Index
    • Reduced Body Fat Percentage
    • Reduced Triglyceride Levels
    • Reduced Blood Cholesterol

    • High evidence

  • ILA-producing bifidobacterium bifidum ameliorates chronic kidney disease via AHR signaling by modulating the gut-kidney axis.

    • 2026-04
    • Food research international (Ottawa, Ont.) 230
    • • Qinglian Hua
      • Yang Meng
      • Jinpeng Hu
      • Yanchen Wei
      • Huaxi Yi
      • Xi Liang
      • Lanwei Zhang
      • Zhe Zhang

    • PubMed: 41794500
    • DOI: 10.1016/j.foodres.2026.118638

    4 Insights on

    • Improved Gut Microbiota Composition
    • Reduced Intestinal Inflammation
    • Reduced Kidney Fibrosis
    • Improved Chronic Kidney Disease Outcomes

    • Low evidence
    • Animal Study

  • Safety and efficacy of a feed additive consisting of Lactobacillus acidophilusCNCM I-3231, Ligilactobacillus salivariusCNCM I-3233, Lacticaseibacillus paracaseiCNCM I-4901, Bifidobacterium longumCNCM I-3227 and Bifidobacterium animalis subsp. lactisCNCM I-3993 (FlorEquilibre® Chat) for cats (WAMINE SAS).

    • 2026-04
    • Review
    • EFSA journal. European Food Safety Authority 24(4)
    • • Roberto Edoardo Villa
      • Giovanna Azimonti
      • Eleftherios Bonos
      • Henrik Christensen
      • Mojca Durjava
      • Birgit Dusemund
      • Ronette Gehring
      • Boet Glandorf
      • Maryline Kouba
      • Marta López-Alonso
      • Francesca Marcon
      • Carlo Nebbia
      • Alena Pechová
      • Miguel Prieto-Maradona
      • Katerina Theodoridou
      • Giovanna Martelli
      • Secundino López-Puente
      • Maria Saarela
      • Montserrat Anguita
      • Jaume Galobart
      • Matteo L Innocenti
      • Jordi Ortuño
      • Sofia Sandalli
      • Rosella Brozzi

    • PubMed: 41960172
    • DOI: 10.2903/j.efsa.2026.10030

    3 Insights on

    • Improved Stability of Gut Microbiota
    • Adverse Safety Concern from Antimicrobial Resistance
    • No Efficacy in Cats

    • Low evidence

  • Chitosan and sulfated glucan nanoparticles: A novel strategy for cryopreservation of Lactobacillus plantarum.

    • 2026-04
    • Food research international (Ottawa, Ont.) 230
    • • Tingyue Deng
      • Xiaowei Shen
      • Zeyu Han
      • Jing Liu
      • Bolin Zhang
      • Hongfei Zhao

    • PubMed: 41794538
    • DOI: 10.1016/j.foodres.2026.118549

    1 Insight on

    • Improved Survival During Cryopreservation

    • Low evidence

  • Ingestion of diverse protein-rich whole-foods result in similar post exercise whole body and myofibrillar protein synthesis rates compared with a more isolated protein source in young adults.

    • 2026-04
    • RCT · n = 11
    • The American journal of clinical nutrition 123(4)
    • • Freyja Ad Haigh
      • Alistair J Monteyne
      • Doaa R Abdelrahman
      • Andrew J Murton
      • Tim Ja Finnigan
      • Hannah E Theobald
      • Francis B Stephens
      • Benjamin T Wall

    • PubMed: 41643855
    • DOI: 10.1016/j.ajcnut.2026.101231

    2 Insights on

    • Improved Whole Body Net Protein Balance
    • Increased Myofibrillar Protein Synthesis

    • High evidence

  • The role of Lactobacillus in dibutyl phthalate-induced gut and liver injury: Probiotic intervention and multi-omics evidence.

    • 2026-04
    • Ecotoxicology and environmental safety 314
    • • Siming Huo
      • Bo Li
      • Jiayu Du
      • Zheng Cao

    • PubMed: 41895142
    • DOI: 10.1016/j.ecoenv.2026.120051

    2 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Liver Injury

    • Low evidence
    • Animal Study

  • Multi-Strain Probiotics BLa80, LRa05, and BBr60 Modulate Inflammation, Bile Acids, and Gut Microbiota in Type 2 Diabetes: A Randomized Controlled Trial.

    • 2026-04
    • RCT · n = 80
    • Food science & nutrition 14(4)
    • • Sijia Zhu
      • Yan Qiao
      • Wenjing He
      • Yaojie Xiao
      • Guiqin Song
      • Kang Liu
      • Shuguang Fang

    • PubMed: 41971606
    • DOI: 10.1002/fsn3.71735

    11 Insights on

    • Reduced Tumor Necrosis Factor Alpha
    • Increased Short-Chain Fatty Acid Production
    • Reduced Inflammation
    • Reduced Interleukin-1β Levels
    • Improved Fasting Plasma Glucose
    • Altered Bile Acid Metabolism
    • Improved Glycemia
    • Reduced Glycated Hemoglobin
    • Reduced Threonine
    • Reduced Isoleucine Level
    • Reduced Arginine Level

    • High evidence

  • Effect of Vitamin D Supplementation on Metabolic Parameters in Patients with Metabolic-Associated Fatty Liver Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    • 2026-04
    • Meta-Analysis
    • The Journal of nutrition 156(4)
    • • Bowen Yu
      • Junyan Liu
      • Fangfang Bu
      • Hongli Yan
      • Chen Chen
      • Yanfei Li
      • Yifei Sun
      • Yaqin Wang
      • Junhua Yuan

    • PubMed: 41478593
    • DOI: 10.1016/j.tjnut.2025.101314

    9 Insights on

    • Reduced Triglyceride Levels
    • Improved Insulin Levels
    • Reduced LDL Cholesterol
    • Reduced Blood Cholesterol
    • Reduced Fasting Blood Glucose Levels
    • Increased High-Density Lipoprotein Cholesterol
    • Reduced Alanine Aminotransferase Level
    • Reduced HOMA-IR
    • Reduced Aspartate Aminotransferase Level

    • High evidence

  • Effects of probiotic supplementation on growth performance, intestinal barrier function, and oxidative stress in broiler chickens fed a deoxynivalenol-contaminated diet.

    • 2026-04
    • RCT · n = 432
    • Poultry science 105(4)
    • • Kouassi R Kpodo
      • Yuguo H Tompkins
      • Katarzyna B Miska
      • Monika Proszkowiec-Weglarz
      • Olga A Postnikova
      • Drew E Olson
      • Trevor R Mitchell
      • Anthony E Glenn

    • PubMed: 41619488
    • DOI: 10.1016/j.psj.2026.106501

    4 Insights on

    • Improved Oxidative Status
    • Improved Oxidative Stress Resistance
    • No Improvement in Growth Performance
    • Lack of Protection of Intestinal Morphology Against DON

    • Low evidence
    • Animal Study

  • Diagnostic Criteria and Management of MELAS and Stroke-Like Episodes: Consensus-Based Statements.

    • 2026-04
    • Systematic Review
    • European journal of neurology 33(4)
    • • Michelangelo Mancuso
      • Marcello Bellusci
      • Valerio Carelli
      • Irenaeus de Coo
      • Daria Diodato
      • Felix Distelmaier
      • Omar Hikmat
      • Michio Hirano
      • Rita Horvath
      • Amel Karaa
      • Thomas Klopstock
      • Mary Kay Koenig
      • Cornelia Kornblum
      • Chiara La Morgia
      • Piervito Lopriore
      • Mika Henrik Martikainen
      • Robert McFarland
      • Olimpia Musumeci
      • Robert D S Pitceathly
      • Guido Primiano
      • Shamima Rahman
      • Fernando Scaglia
      • Andrew Schaefer
      • Manuel Schiff
      • Luisa Semmler
      • Costanza Lamperti
      • Serenella Servidei

    • PubMed: 41999163
    • DOI: 10.1111/ene.70588

    1 Insight on

    • Reduced Stroke-Like Episode Severity

    • High evidence

  • Clostridium butyricum ameliorates atherosclerotic inflammation through regulation of gut microbiota.

    • 2026-04
    • International immunopharmacology 174
    • • Jing Wang
      • Junbai Ma
      • Yiwei Li
      • Yuanyuan Liu
      • Wenke Shen
      • Jian Liu
      • Hao Wang
      • Yuhong Zhang
      • Xiaoxia Zhang

    • PubMed: 41707593
    • DOI: 10.1016/j.intimp.2026.116315

    3 Insights on

    • Improved Gut Microbiota Composition
    • Reduced Inflammation
    • Reduced Atherosclerosis

    • Low evidence
    • Animal Study

  • Synergistic effects of oral inoculation with recombinant Lactobacillus plantarum NC8 Co-expressing interleukin-2, interleukin-17b and interleukin-26 on infectious bronchitis vaccination in chickens.

    • 2026-04
    • Clinical Trial
    • Poultry science 105(4)
    • • Junjie Peng
      • Shaohua Guo
      • Yanyan Liu
      • Weiwei Hao
      • Xin Yang
      • Shanshan Zhu
      • Rong Gao

    • PubMed: 41633076
    • DOI: 10.1016/j.psj.2026.106551

    1 Insight on

    • Enhanced Immune Response

    • Low evidence
    • Animal Study

  • Effects of Bifidobacterium animalis subsp. lactis IMAU12267 on milk fermentation, subsequent storage, and functional properties.

    • 2026-04
    • Food chemistry: X 35
    • • Xiao Liu
      • Sheng Zhang
      • Lu Li
      • Yongfu Chen
      • Jianli Li

    • PubMed: 41971400
    • DOI: 10.1016/j.fochx.2026.103791

    1 Insight on

    • Improved Storage Viability

    • Low evidence

  • Determination of Folate Bioavailability From Brewer's Yeast in a Dual Isotope Randomized Human Intervention Study.

    • 2026-04
    • RCT
    • Molecular nutrition & food research 70(7)
    • • Nadine Weber
      • Lisa Striegel
      • Yvonne Methner
      • Beate Brandl
      • Viola Groehn
      • Jean-Pierre Knapp
      • Thomas Skurk
      • Michael Rychlik

    • PubMed: 41954190
    • DOI: 10.1002/mnfr.70453

    1 Insight on

    • Increased Folate Bioavailability

    • High evidence
    • Rigorous Journal

  • Randomized Trial of Milk Oral Immunotherapy: Fixed Low-Dose vs Escalation to Medium-Dose.

    • 2026-04
    • RCT · n = 32
    • The journal of allergy and clinical immunology. In practice 14(4)
    • • Ken-Ichi Nagakura
      • Kyohei Takahashi
      • Yoko Miura
      • Kaito Goto
      • Akira Kawai
      • Naoko Fusayasu
      • Kiyotake Ogura
      • Sakura Sato
      • Motohiro Ebisawa
      • Noriyuki Yanagida

    • PubMed: 41633410
    • DOI: 10.1016/j.jaip.2026.01.025

    5 Insights on

    • Improved Milk Tolerance
    • Reduced Milk-Specific Immunoglobulin E Level
    • Reduced Casein-Specific IgE Level
    • Reduced α-Lactalbumin-Specific IgE Level
    • Reduced β-Lactoglobulin-Specific IgE Level

    • High evidence

  • An exopolysaccharide-rich fraction from Bifidobacterium animalis subsp. lactis MG741 ameliorates high-fat diet-induced MASLD by enhancing intestinal barrier function.

    • 2026-04
    • International journal of biological macromolecules 359
    • • Hee-Jin Kim
      • Hee-Kyoung Son
      • Yu Ra Lee
      • Yejin Ahn
      • Hye-Bin Lee
      • Ji-Yeon Lee
      • Miri Park
      • Jae-Ho Park
      • Ho-Young Park

    • PubMed: 41937014
    • DOI: 10.1016/j.ijbiomac.2026.151802

    6 Insights on

    • Reduced Hepatic Steatosis
    • Reduced Metabolic Endotoxemia
    • Improved Glucose Metabolism
    • Improved Gut Barrier Function
    • Reduced Weight Gain and Fat Mass
    • Reduced Circulating Endotoxin

    • Low evidence

  • Lactobacillus johnsonii and 3-indolepropionic acid improve the depression-like behaviors via inhibiting neuroinflammation.

    • 2026-04
    • Pharmacological research 226
    • • Jing Xie
      • Yongzhi Zhang
      • Jiao-Lin Wang
      • Fei He
      • Ke Xu
      • Jianjun Chen
      • Peng Xie

    • PubMed: 41825730
    • DOI: 10.1016/j.phrs.2026.108158

    3 Insights on

    • Reduced Neuroinflammation
    • Reduced Depression Symptoms
    • Increased IPA Levels

    • Low evidence
    • Animal Study

  • Could taurine supplementation improve graft functions after liver transplantation? A randomized clinical trial among liver transplant recipients.

    • 2026-04
    • RCT · n = 225
    • Clinical nutrition ESPEN 72
    • • Shaghayegh Mottaghi
      • Afsaneh Vazin
      • Hamed Nikoupour
      • Seyed Mohammad Firoozifar
      • Elham Haem
      • Reza Heidari
      • Mojtaba Shafiekhani

    • PubMed: 41605371
    • DOI: 10.1016/j.clnesp.2026.102920

    8 Insights on

    • Reduced Mortality Risk
    • Reduced Duration of Mechanical Ventilation
    • Reduced Alanine Aminotransferase Level
    • Reduced Total Bilirubin Level
    • Reduced Aspartate Aminotransferase Level
    • Reduced Hospital Stay
    • Reduced Intensive Care Unit Stay
    • Reduced International Normalized Ratio

    • High evidence
    • Large Human Trial

  • Bifidobacterium supplementation ameliorates LPS-induced immune stress and intestinal barrier dysfunction in goslings.

    • 2026-04
    • RCT · n = 288
    • Poultry science 105(4)
    • • Cihang Zhang
      • Usman Nazir
      • Shi Chen
      • Zhi Yang
      • Zhiyue Wang
      • Haiming Yang

    • PubMed: 41616533
    • DOI: 10.1016/j.psj.2026.106512

    4 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Intestinal Inflammation
    • Improved Growth Performance
    • Increased Antioxidant Capacity

    • Low evidence
    • Animal Study

  • Lacto-N-neotetraose and Bifidobacterium longum ssp. infantis together shape the unique gut microbiota and metabolites of allergic mice.

    • 2026-04
    • Journal of dairy science 109(4)
    • • Yi Shan
      • Xue Han
      • Yu Sun
      • Jiuyuan Wang
      • Yanfeng Qu

    • PubMed: 41780875
    • DOI: 10.3168/jds.2025-27877

    3 Insights on

    • Improved Gut Microbiota Composition
    • Reduced Intestinal Tissue Injury
    • Reduced Food Allergy Symptoms

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • A pilot feasibility study of nurse-led psyllium supplementation for metabolic health in hospitalized patients with schizophrenia.

    • 2026-04
    • Clinical Trial
    • Archives of psychiatric nursing 61
    • • Ru-Shin Jang
      • Chin-Chou Yang
      • Wen-Jiuan Yen
      • Mei-Ling Lin

    • PubMed: 41956574
    • DOI: 10.1016/j.apnu.2026.152072

    3 Insights on

    • Reduced Waist Circumference
    • Reduced Triglyceride Levels
    • Stabilized Blood Glucose Level

    • Moderate evidence

  • Dietary Vitamin B6 Intake and Gastroesophageal Reflux Disease: A Case-Control Study.

    • 2026-04
    • Observational · n = 150
    • JGH open : an open access journal of gastroenterology and hepatology 10(4)
    • • Amirhesam Mehrara
      • Saba Moradi
      • Masoumeh Dorosti
      • Leila Dehghanian
      • Masoumeh Sadat MirShafaie
      • Mohammadreza Esfahanian
      • Bita Moradi
      • Ali Nouri
      • Sara Khoshdooz
      • Parsa Bahmani
      • Saeid Doaei
      • Maryam Gholamalizadeh

    • PubMed: 41994477
    • DOI: 10.1002/jgh3.70398

    1 Insight on

    • Increased Risk of Gastroesophageal Reflux Disease

    • High evidence

  • Bacteriocin gene-mediated ecological adaptation of Bifidobacterium breve in the adult human gut.

    • 2026-04
    • Clinical Trial
    • Cell genomics 6(4)
    • • Jingyu Wang
      • Xin Qian
      • Qing Li
      • Zhiying Jin
      • Na Liu
      • Jianxin Zhao
      • Wei Chen
      • Shaopu Wang
      • Peijun Tian

    • PubMed: 41421358
    • DOI: 10.1016/j.xgen.2025.101106

    2 Insights on

    • Improved Stability of Gut Microbiota
    • Improved Strain-Level Competitive Fitness

    • Moderate evidence

  • Alginate alleviates hyperuricemia by modulating the Pediococcus acidilactici LW1-1-butyrate-NLRP3 inflammasome axis.

    • 2026-04
    • International journal of biological macromolecules 354
    • • Yukun Li
      • Rongshuang Han
      • Rong Wang
      • Xiaoyan Zhang
      • Mengchen Shan
      • Tianyu Fu
      • Yupeng Li
      • Xingsi Qi
      • Bin Cao
      • Yi Wang
      • Tao Mao
      • Zibin Tian

    • PubMed: 41819315
    • DOI: 10.1016/j.ijbiomac.2026.151318

    4 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Uric Acid Levels
    • Reduced Intestinal Inflammation
    • Increased Uric Acid Excretion

    • Low evidence
    • Animal Study

  • Lactobacillus plantarum Dynamically Changes the Fermentation Characteristics and Active Ingredients of Summer/Autumn Tea Leaves.

    • 2026-04
    • Food science & nutrition 14(4)
    • • Yimei Luo
      • Yuangan Qian
      • Yangwen Ou
      • Shimin Tian
      • Yixiao Xie
      • Yulong Zheng
      • Jun Hao
      • Hong Sun
      • Fuyu Yang

    • PubMed: 42005329
    • DOI: 10.1002/fsn3.71773

    3 Insights on

    • Altered Gut Microbial Community
    • Reduced Bitter-Related Organic Acids
    • Increased Flavor-Related Free Amino Acids

    • Low evidence

  • Preparation of fermented plant-based beverages using grape seed: Comparison of lactic acid bacteria strains, physicochemical characteristics and flavor profiles.

    • 2026-04
    • Food chemistry: X 35
    • • Ruiguo Cui
      • Yuting Xiao
      • Lixiang Huai
      • Jialin Xue
      • Zheshuo Cui
      • Caihong Cheng
      • Xiaoyu Liu
      • Lijun Song

    • PubMed: 42011494
    • DOI: 10.1016/j.fochx.2026.103845

    2 Insights on

    • Increased Antioxidant Activity
    • Increased Asparagine Levels

    • Low evidence

  • Probiotic and antibacterial properties of recombinant Lactococcus lactis expressing the fusion antimicrobial peptides BMAP18-BSN37 in mice and chickens.

    • 2026-04
    • Poultry science 105(4)
    • • Ruibiao Wang
      • Yukai Lin
      • Yu Xia
      • Suxian Liu
      • Doudou Feng
      • Siyang Li
      • Tengyue Zhou
      • Huarun Sun
      • Jiyuan Shen
      • Bo Wen
      • Minghui Li
      • Chengshui Liao
      • Baoliang Qin
      • Jianhe Hu
      • Yuanfang Ma
      • Ke Ding
      • Lei Wang

    • PubMed: 41616534
    • DOI: 10.1016/j.psj.2026.106507

    4 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Intestinal Inflammation
    • Improved Growth Performance
    • Reduced Salmonella Colonization

    • Low evidence
    • Animal Study

  • Leucine supplementation does not attenuate the decline in daily muscle protein synthesis rates or preserve leg muscle mass during leg immobilization in young or older adults: a double-blind randomized trial.

    • 2026-04
    • RCT
    • The American journal of clinical nutrition 123(4)
    • • Tyler A Churchward-Venne
      • Philippe Jm Pinckaers
      • Joey Sj Smeets
      • Gabriel Nasri Marzuca-Nassr
      • Stefan Hm Gorissen
      • Cas J Fuchs
      • Joan M Senden
      • Joy Pb Goessens
      • Annemie P Gijsen
      • Will Kwh Wodzig
      • Luc Jc van Loon

    • PubMed: 41580240
    • DOI: 10.1016/j.ajcnut.2026.101205

    2 Insights on

    • Reduced Muscle Protein Synthesis Rate
    • Reduced Quadriceps Muscle Cross-Sectional Area

    • High evidence

  • Legume Intake and Glycemic Control in Individuals With or at Risk of Metabolic Syndrome: Multi-Omics Insights From Both Observational and Interventional Evidence.

    • 2026-04
    • Observational · n = 82
    • Molecular nutrition & food research 70(7)
    • • Guoqing Ma
      • Haozhi Niu
      • Junqi Li
      • Nan Yang
      • Xia Liao
      • Hang Yu
      • Haixia Yang
      • Tian Tian
      • Qian Wang
      • Xin Liu

    • PubMed: 41954199
    • DOI: 10.1002/mnfr.70463

    1 Insight on

    • Improved Fasting Plasma Glucose

    • High evidence
    • Rigorous Journal

  • Improvement of starch fine structure, physicochemical properties and digestive characteristics of adlay seeds by fermentation with Lactobacillus plantarum and Lactobacillus paracasei.

    • 2026-04
    • International journal of biological macromolecules 355
    • • Shuang Xu
      • Weijie Qi
      • Yaxing Xie
      • Jianjun Cheng
      • Qingfeng Ban

    • PubMed: 41861878
    • DOI: 10.1016/j.ijbiomac.2026.151547

    3 Insights on

    • Improved Palatability and Textural Quality
    • Increased Resistant Starch
    • Reduced Rapidly Digestible Starch

    • Low evidence

  • Development of a propidium monoazide-droplet digital polymerase chain reaction assay for strain-specific quantification of Lactiplantibacillus plantarum YZH81 in fermented milk.

    • 2026-04
    • Journal of dairy science 109(4)
    • • Zhihao Wang
      • Yanrong Liu
      • Zhongfa Tan
      • Chi Zhang
      • Xiaoli Wang
      • Yao Yang

    • PubMed: 41485570
    • DOI: 10.3168/jds.2025-27317

    1 Insight on

    • Strain-Specific Lactiplantibacillus Plantarum Quantification

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Safety and toxicity assessment of Lactobacillus salivarius AP-32 with Probiotic potential in vivo and in vitro.

    • 2026-04
    • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 210
    • • Yu-Hsuan Chin
      • Yi-Wen Chen
      • Yen-Yu Huang
      • Ching-Min Li
      • Jia-Hung Lin
      • Yi-Wei Kuo
      • Chen-Yu Chen
      • Yen-Feng Lee
      • Cian-Dai Ciou
      • Ko-Chiang Hsia
      • Shin-Yu Tsai
      • Hsieh-Hsun Ho

    • PubMed: 41577224
    • DOI: 10.1016/j.fct.2026.115970

    4 Insights on

    • Reduced Pathogen Growth
    • Improved Probiotic Safety
    • No Mutagenic Effects
    • Induced Immunomodulatory Effects

    • Low evidence

  • Effect of diet intervention on symptoms in autism spectrum disorder: An umbrella review.

    • 2026-04
    • Systematic Review · n = 5,033
    • Research in developmental disabilities 171
    • • Jiaxin Shi
      • Yichao Cheng
      • Yenan Wei
      • Yongbo Shi
      • Zhimei Jiang

    • PubMed: 41865680
    • DOI: 10.1016/j.ridd.2026.105270

    1 Insight on

    • Improved Overall IBS Symptoms

    • High evidence

  • Postbiotic_Loaded Hyalurosome: Investigating Their Potential as Antimicrobial and Antioxidant Agents.

    • 2026-04
    • Journal of cosmetic dermatology 25(4)
    • • Seyede Fateme Morakabi
      • Mahvash Khodabandeh Shahraky
      • Gholamreza Ahmadian
      • Roghayeh Mokhtari Asl

    • PubMed: 41999161
    • DOI: 10.1111/jocd.70777

    2 Insights on

    • Reduced Cytotoxicity
    • Improved Antioxidant Activity

    • Low evidence

  • Prebiotics of Lactobacillus plantarum mitigate inflammation but compromise immunity.

    • 2026-04
    • Microbial pathogenesis 213
    • • Shanshan Yang
      • Qiuxia Cao
      • Kexin Yan
      • Zhenkong Cheng
      • Jianhao Zheng
      • Baochao Fan
      • Xu Song
      • Xianyu Bian
      • Gege Zhang
      • Xuesong Yuan
      • Rongli Guo
      • Yuanyuan Wang
      • Hailin Huan
      • Chuping Luo
      • Junshu Yan
      • Bin Li

    • PubMed: 41651082
    • DOI: 10.1016/j.micpath.2026.108363

    2 Insights on

    • Reduced Inflammation
    • Reduced Immune Cell Activity

    • Low evidence
    • Animal Study

  • Exploring the Hypoglycemic Activity and Mechanism of Polyphenols From Highland Barley Through Lactobacillus acidophilus Fermentation.

    • 2026-04
    • Journal of food science 91(4)
    • • Mengyao Zhu
      • Xu Guo
      • Yingying Chen
      • Shutao Sun
      • Qidong Ren
      • Muxuan Wang
      • Mengqi Zhang
      • Chao Liu
      • Ningyang Li

    • PubMed: 41972482
    • DOI: 10.1111/1750-3841.71061

    4 Insights on

    • Increased Antioxidant Activity
    • Reduced Enzyme Activity
    • Improved Glucose Metabolism
    • Increased Bioavailability of Phenolics

    • Low evidence
    • Rigorous Journal

  • Integrated omics-based analysis reveals the role of ferulic acid activating a co-production of 4-vinyl guaiacol and fumaric acid by Rhizopus oryzae.

    • 2026-04
    • Bioresource technology 445
    • • Xin Li
      • Shanshan Wu
      • Xueyu Tang

    • PubMed: 41638588
    • DOI: 10.1016/j.biortech.2026.134146

    2 Insights on

    • Increased Fumaric Acid Production
    • Simultaneous 4-Vinyl Guaiacol Production

    • Low evidence

  • Vaginal microbiota impacts of a Lactobacillus crispatus live biotherapeutic and predictors of colonization in randomized controlled trial.

    • 2026-04
    • RCT
    • Cell host & microbe 34(4)
    • • Seth M Bloom
      • Laura Symul
      • Joseph Elsherbini
      • Jiawu Xu
      • Salina Hussain
      • Johnathan Shih
      • Ashley Sango
      • Caroline M Mitchell
      • Anke Hemmerling
      • Thomas P Parks
      • Aditi Kannan
      • Fatima A Hussain
      • Craig R Cohen
      • Susan P Holmes
      • Douglas S Kwon

    • PubMed: 41903526
    • DOI: 10.1016/j.chom.2026.03.003

    1 Insight on

    • Reduced Recurrence of Bacterial Vaginosis

    • High evidence

  • Oral delivery of engineered Lactococcus lactis microcapsules expressing antioxidant enzymes for inflammatory bowel disease: Mechanisms of intestinal barrier repair and microbiota modulation.

    • 2026-04
    • Materials today. Bio 37
    • • Yue Meng
      • Chao Miao
      • Jiaxin Guo
      • Wei Zhang
      • Ling Guo
      • Yu Zhang
      • Yujun Jiang

    • PubMed: 41716339
    • DOI: 10.1016/j.mtbio.2026.102902

    3 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Intestinal Inflammation
    • Improved Gut Microbiota Homeostasis

    • Low evidence

  • Arginine therapy in sickle cell disease: A systematic review and meta-analysis of clinical outcomes.

    • 2026-04
    • Meta-Analysis · n = 830
    • Clinical nutrition ESPEN 72
    • • Favour M L Foncha
      • Joseph Y Bena Nnang
      • Samuel G J Fodop
      • Best C I Poudjoum
      • Dimitri S Tcheuko
      • Joel G K Mekontso

    • PubMed: 41534622
    • DOI: 10.1016/j.clnesp.2025.102898

    5 Insights on

    • Reduced Length of Hospital Stay
    • Reduced Pain
    • Reduced Opioid Consumption
    • Reduced Time to Crisis Resolution
    • Reduced Hospital Readmission Risk

    • High evidence