October 2024 Supplement Research Papers

• October 1

  • Impact of probiotic supplementation on exercise endurance among nonelite athletes: a randomized, placebo-controlled, double-blind, clinical trial.

    • 2024-10-01
    • RCT
    • Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 49(10)
    • • Caitlin E McDermott
      • Taylor C Judkins
      • Heather K Vincent
      • Tyler Culpepper
      • James Colee
      • Carmelo Nieves
      • Anne E Mathews
      • Bobbi Langkamp-Henken

    • PubMed: 39018571
    • DOI: 10.1139/apnm-2024-0142

    4 Insights on

    • Reduced Gastrointestinal Symptoms
    • Reduced Cold Symptoms
    • Increased Exercise Endurance
    • Increased Physical Activity

    • High evidence
• October 2

  • Eight-Week Supplementation With Bifidobacterium lactis HN019 and Functional Constipation: A Randomized Clinical Trial.

    • 2024-10-02
    • RCT · n = 283
    • JAMA network open 7(10)
    • • Jing Cheng
      • Carl Gao
      • Reeta Ala-Jaakkola
      • Sofia D Forssten
      • Markku Saarinen
      • Ashley Hibberd
      • Arthur C Ouwehand
      • Alvin Ibarra
      • Dingqiang Li
      • Anders Nordlund
      • Yingxin Wang
      • Xizhong Shen
      • Haixia Peng
      • Xinjian Wan
      • Xiangjun Meng

    • PubMed: 39356506
    • DOI: 10.1001/jamanetworkopen.2024.36888

    4 Insights on

    • Improved Bowel Movement Frequency
    • Increased Complete Spontaneous Bowel Movements
    • Improved Bowel Movements
    • Improved Constipation

    • High evidence
    • Large Human Trial
• October 3

  • Gut Lactococcus garvieae promotes protective immunity to foodborne Clostridium perfringens infection.

    • 2024-10-03
    • Microbiology spectrum 12(10)
    • • Xue-Yin Wang
      • Fan-Hua Meng
      • Ming-Yue Zhang
      • Fen-Xin Li
      • Yu-Xin Lei
      • Zhao-Guo Ma
      • Jia-Qi Li
      • Ya-Nan Lou
      • Yue-Feng Chu
      • Ke Ma
      • Shui-Xing Yu

    • PubMed: 39190634
    • DOI: 10.1128/spectrum.04025-23

    7 Insights on

    • Improved Gut Microbiota Composition
    • Improved Intestinal Barrier Function
    • Reduced Dysbiosis
    • Reduced Inflammation
    • Improved Resistance to Infections
    • Enhanced Resistance to Bacterial Infections
    • Reduced Pathogen Colonization

    • Low evidence
    • Animal Study

  • The role of selected nutraceuticals in management of prediabetes and diabetes: An updated review of the literature. Part II.

    • 2024-10-03
    • Review
    • Phytotherapy research : PTR 38(11)
    • • Giuseppe Derosa
      • Angela D'Angelo
      • Pamela Maffioli

    • PubMed: 39363526
    • DOI: 10.1002/ptr.8312

    2 Insights on

    • Reduced Blood Glucose Levels
    • Improved Homeostasis

    • Low evidence
• October 5

  • A Synbiotic Combining Chitin-Glucan and Lactobacillus acidophilus NCFM Induces a Colonic Molecular Signature Soothing Intestinal Pain and Inflammation in an Animal Model of IBS.

    • 2024-10-05
    • International journal of molecular sciences 25(19)
    • • Lena Capirchio
      • Christel Rousseaux
      • Caroline Dubuquoy
      • Arthur C Ouwehand
      • Véronique Maquet
      • Salvatore Modica
      • Edouard Louis
      • Pierre Desreumaux
      • Jan Tack

    • PubMed: 39409061
    • DOI: 10.3390/ijms251910732

    2 Insights on

    • Reduced Intestinal Inflammation
    • Reduced Visceral Hypersensitivity

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • The supplementation of L-carnitine in critically ill patients with sepsis: a systematic review and meta-analysis of randomized controlled trials.

    • 2024-10-05
    • Meta-Analysis · n = 356
    • European journal of medical research 29(1)
    • • Chang Meng
      • Yudan Ma
      • Ning Fu
      • Jie Li
      • Biao Sun
      • Zhichao Li
      • Qing Wang
      • Peng Liu

    • PubMed: 39367436
    • DOI: 10.1186/s40001-024-02087-w

    1 Insight on

    • Reduced Mortality Rate

    • High evidence
• October 7

  • Microencapsulation of Bifidobacterium lactis and Lactobacillus plantarum within a Novel Polysaccharide-Based Core-Shell Formulation: Improving Probiotic Viability and Mucoadhesion.

    • 2024-10-07
    • ACS biomaterials science & engineering 10(11)
    • • Timothy Schofield
      • John Kavanagh
      • Zhongyan Li
      • Alexandra O'Donohue
      • Aaron Schindeler
      • Fariba Dehghani
      • Sepehr Talebian
      • Peter Valtchev

    • PubMed: 39370825
    • DOI: 10.1021/acsbiomaterials.4c00852

    1 Insight on

    • Improved Gastric Survival

    • Low evidence
    • Animal Study
• October 8

  • Antimicrobial Peptides Derived from Bacteria: Classification, Sources, and Mechanism of Action against Multidrug-Resistant Bacteria.

    • 2024-10-08
    • Review
    • International journal of molecular sciences 25(19)
    • • Raynichka Mihaylova-Garnizova
      • Slavena Davidova
      • Yordan Hodzhev
      • Galina Satchanska

    • PubMed: 39409116
    • DOI: 10.3390/ijms251910788

    2 Insights on

    • Reduced Clostridium difficile Infection
    • Reduced Salmonella Infection

    • Moderate evidence
    • Rigorous Journal

  • Are probiotics useful in the treatment of chronic idiopathic constipation in adults? A review of existing systematic reviews, meta-analyses, and recommendations.

    • 2024-10-08
    • Review
    • Przeglad gastroenterologiczny 15(2)
    • • Mikołaj Kamiński
      • Karolina Skonieczna-Żydecka
      • Igor Łoniewski
      • Anastasios Koulaouzidis
      • Wojciech Marlicz

    • PubMed: 32550942
    • DOI: 10.5114/pg.2019.86747

    1 Insight on

    • Improved Chronic Constipation

    • Low evidence

  • Investigating the effects of co-supplementation with alpha-linolenic acid and L-carnitine on inflammatory status, oxidative stress, clinical symptoms, mental health and quality of life in women with migraine: a protocol for a randomized, triple-blind, placebo-controlled trial.

    • 2024-10-08
    • RCT · n = 80
    • Trials 25(1)
    • • Sahar Golpour-Hamedani
      • Mohammad Bagherniy
      • Fariborz Khorvash
      • Awat Feizi
      • Manoj Sharma
      • Gholamreza Askari

    • PubMed: 39380085
    • DOI: 10.1186/s13063-024-08500-3

    11 Insights on

    • Improved Quality of Life
    • Improved Antioxidant Capacity
    • Improved Mental Health
    • Improved Sleep Quality
    • Reduced C-Reactive Protein Levels
    • Reduced Migraine Severity
    • Reduced Migraine Frequency
    • Reduced Migraine Duration
    • Reduced Malondialdehyde
    • Improved Superoxide Dismutase Level
    • Reduced Nitric Oxide Level

    • High evidence

  • Lacticaseibacillus rhamnosus LRa05 mediates dynamic regulation of intestinal microbiota in mice with low-dose DSS-induced chronic mild inflammation.

    • 2024-10-08
    • Frontiers in microbiology 15
    • • Yao Dong
      • Zhonghui Gai
      • Mei Han
      • Yunjiao Zhao

    • PubMed: 39444683
    • DOI: 10.3389/fmicb.2024.1483104

    4 Insights on

    • Improved Liver Function
    • Improved Gut Microbiota Balance
    • Reduced Inflammation
    • Reduced Metabolic Endotoxemia

    • Low evidence
• October 9

  • Effect of cholecalciferol versus calcifediol on serum 25(OH)D concentrations: a systematic review with meta-analysis.

    • 2024-10-09
    • Meta-Analysis · n = 1,575
    • European journal of clinical nutrition 79(4)
    • • Selma Bouden
      • Meriam Ben Messaoud
      • Olfa Saidane
      • Leila Rouached
      • Aicha Ben Tekaya
      • Ines Mahmoud
      • Rawdha Tekaya
      • Chedly Dziri
      • Leila Abdelmoula

    • PubMed: 39385006
    • DOI: 10.1038/s41430-024-01520-x

    1 Insight on

    • Increased 25-hydroxyvitamin D Level

    • High evidence
    • Rigorous Journal

  • Impact of Maternal Moringa oleifera Leaf Supplementation on Milk and Serum Vitamin A and Carotenoid Concentrations in a Cohort of Breastfeeding Kenyan Women and Their Infants.

    • 2024-10-09
    • RCT · n = 50
    • Nutrients 16(19)
    • • Suzanna Labib Attia
      • Silvia A Odhiambo
      • Jerusha N Mogaka
      • Raphael Ondondo
      • Aric Schadler
      • Kristen McQuerry
      • George J Fuchs
      • Janet E Williams
      • Michelle K McGuire
      • Carrie Waterman
      • Kerry Schulze
      • Patrick M Owuor

    • PubMed: 39408390
    • DOI: 10.3390/nu16193425

    5 Insights on

    • Increased Milk Alpha-Carotene Concentration
    • Increased Milk Vitamin A Concentration
    • Improved Maternal Vitamin A Status
    • Improved Vitamin A Status
    • Increased Milk Carotenoid Level

    • High evidence
    • Rigorous Journal

  • Breaking the mold: nontraditional approaches to allergen immunotherapy for environmental allergens.

    • 2024-10-09
    • Review
    • Immunotherapy 16(18-19)
    • • Rashi Ramchandani
      • Rachel Lucyshyn
      • Sophia Linton
      • Anne K Ellis

    • PubMed: 39382452
    • DOI: 10.1080/1750743x.2024.2408216

    1 Insight on

    • Reduced Allergic Symptoms

    • Low evidence
• October 10

  • Gut Microbiome and Metabolome Alterations in Overweight or Obese Adult Population after Weight-Loss Bifidobacterium breve BBr60 Intervention: A Randomized Controlled Trial.

    • 2024-10-10
    • RCT
    • International journal of molecular sciences 25(20)
    • • Zhouya Bai
      • Ying Wu
      • Dejiao Gao
      • Yao Dong
      • Yujia Pan
      • Shaobin Gu

    • PubMed: 39456659
    • DOI: 10.3390/ijms252010871

    4 Insights on

    • Reduced Body Mass Index
    • Reduced Body Weight
    • Reduced Fasting Blood Glucose Levels
    • Improved Blood Biochemistry

    • High evidence
    • Rigorous Journal

  • Effect of boswellia (Boswellia serrata L.) supplementation on glycemic markers and lipid profile in type 2 diabetic patients: a systematic review and meta-analysis.

    • 2024-10-10
    • Systematic Review · n = 287
    • Frontiers in clinical diabetes and healthcare 5
    • • Mehdi Karimi
      • Kimia Vakili
      • Pegah Rashidian
      • Seyedeh-Kiana Razavi-Amoli
      • Matin Akhbari
      • Kimia Kazemi

    • PubMed: 39449720
    • DOI: 10.3389/fcdhc.2024.1466408

    4 Insights on

    • Reduced Low-Density Lipoprotein Level
    • Reduced Triglyceride Levels
    • Reduced Hemoglobin A1c
    • Reduced Blood Cholesterol

    • High evidence
• October 11

  • Microbes as medicine.

    • 2024-10-11
    • Review
    • Annals of the New York Academy of Sciences 1541(1)
    • • Brendan A Daisley
      • Emma Allen-Vercoe

    • PubMed: 39392836
    • DOI: 10.1111/nyas.15237

    1 Insight on

    • Improved Gastrointestinal Symptoms

    • Low evidence

  • Novel Antioxidant Peptides from Fermented Whey Protein by Lactobacillus rhamnosus B2-1: Separation and Identification by in Vitro and in Silico Approaches.

    • 2024-10-11
    • Journal of agricultural and food chemistry 72(42)
    • • Hao Guo
      • Chuangang Zang
      • Long Zheng
      • Lin Ding
      • Wenqin Yang
      • Shan Ren
      • Hong Guan

    • PubMed: 39392363
    • DOI: 10.1021/acs.jafc.4c07531

    1 Insight on

    • Improved Antioxidant Activity

    • Low evidence
    • Rigorous Journal

  • Vaginal dysbiosis and the potential of vaginal microbiome-directed therapeutics.

    • 2024-10-11
    • Review
    • Frontiers in microbiomes 3
    • • Valerie Diane Valeriano
      • Emilia Lahtinen
      • In-Chan Hwang
      • Yichan Zhang
      • Juan Du
      • Ina Schuppe-Koistinen

    • PubMed: 41853538
    • DOI: 10.3389/frmbi.2024.1363089

    2 Insights on

    • Restored Vaginal Microbiota
    • Reduced Vaginal Dysbiosis-Associated Infection Risk

    • Low evidence
• October 14

  • Daily Probiotic Ayran Intake Reduces Gingival Inflammation: An Experimental Gingivitis Study.

    • 2024-10-14
    • RCT
    • Oral health & preventive dentistry 22
    • • Bahar Alkaya
      • Mehmet Cenk Haytac
      • Mustafa Özcan
      • Onur Uçak Türer
      • Hamza Gökhan Kayhan
      • Furkan Demirbilek
      • Wim Teughels

    • PubMed: 39400083
    • DOI: 10.3290/j.ohpd.b5784693

    1 Insight on

    • Reduced Gingival Inflammation

    • High evidence
• October 15

  • Probiotics in the non-surgical treatment of periodontitis: a systematic review and network meta-analysis.

    • 2024-10-15
    • Systematic Review · n = 1,290
    • BMC oral health 24(1)
    • • Carlota Duarte de Mendonça
      • António Duarte Sola Pereira da Mata
      • Luís Filipe Ribeiro Azevedo
      • Joana Faria Marques
      • João Miguel Lourenço Silveira
      • Duarte Nuno da Silva Marques

    • PubMed: 39407177
    • DOI: 10.1186/s12903-024-05027-6

    3 Insights on

    • Reduced Probing Pocket Depth
    • Reduced Bleeding on Probing (BOP)
    • Improved Clinical Attachment

    • High evidence
• October 16

  • Vitamin E for people with non-alcoholic fatty liver disease.

    • 2024-10-16
    • Meta-Analysis · n = 708
    • The Cochrane database of systematic reviews 2024(10)
    • • Hongzhu Wen
      • Hongyong Deng
      • Lili Yang
      • Lujin Li
      • Jiang Lin
      • Peiyong Zheng
      • Milica Bjelakovic
      • Guang Ji

    • PubMed: 39412049
    • DOI: 10.1002/14651858.cd015033.pub2

    8 Insights on

    • Reduced All-Cause Mortality
    • Reduced Gamma-Glutamyl Transferase Levels
    • Reduced Alanine Aminotransferase Level
    • Reduced Alkaline Phosphatase Level
    • Reduced Alanine Transaminase Level
    • Reduced Aspartate Aminotransferase Level
    • Improved Physical Health-Related Quality of Life
    • Improved Psychosocial Health-Related Quality of Life

    • High evidence
• October 17

  • A Mix of Probiotic Strains Prevents Hepatic Steatosis, and Improves Oxidative Stress Status and Gut Microbiota Composition in Obese Mice.

    • 2024-10-17
    • Molecular nutrition & food research 68(21)
    • • Chenglin Guo
      • Shengduo He
      • Mélanie Le Barz
      • Sylvie Binda
      • Huahong Wang

    • PubMed: 39420712
    • DOI: 10.1002/mnfr.202300672

    2 Insights on

    • Improved Gut Microbiota Composition
    • Improved Oxidative Status

    • Low evidence
    • Rigorous Journal
    • Animal Study
• October 19

  • The Gut Microbiome Advances Precision Medicine and Diagnostics for Inflammatory Bowel Diseases.

    • 2024-10-19
    • Review
    • International journal of molecular sciences 25(20)
    • • Walaa K Mousa
      • Aya Al Ali

    • PubMed: 39457040
    • DOI: 10.3390/ijms252011259

    2 Insights on

    • Improved Gut Microbiome Composition
    • Improved Disease Management

    • Moderate evidence
    • Rigorous Journal
• October 20

  • Nutritional and Microbial Strategies for Treating Acne, Alopecia, and Atopic Dermatitis.

    • 2024-10-20
    • Review
    • Nutrients 16(20)
    • • Alejandro Borrego-Ruiz
      • Juan J Borrego

    • PubMed: 39458553
    • DOI: 10.3390/nu16203559

    2 Insights on

    • Improved Skin Health
    • Reduced Skin Inflammation

    • Moderate evidence
    • Rigorous Journal
• October 21

  • The effect of adding pancreatin to standard otilinium bromide and simethicone treatment in type 2 diabetes mellitus patients with irritable bowel syndrome.

    • 2024-10-21
    • Observational · n = 121
    • Scientific reports 14(1)
    • • Hulusi Can Karpuzcu
      • Beril Turan Erdoğan
      • Çağdaş Erdoğan

    • PubMed: 39433866
    • DOI: 10.1038/s41598-024-74694-w

    3 Insights on

    • Improved Stool Consistency
    • Improved Quality of Life
    • Reduced Abdominal Pain

    • High evidence
    • Rigorous Journal
• October 22

  • The Impact of Fermented Milk Products Containing Bifidobacterium longum BB536 on the Gut Environment: A Randomized Double-Blind Placebo-Controlled Trial.

    • 2024-10-22
    • RCT
    • Nutrients 16(21)
    • • Ryuta Ejima
      • Riko Mishima
      • Akira Sen
      • Kana Yamaguchi
      • Eri Mitsuyama
      • Hiroki Kaneko
      • Madoka Kimura
      • Satoshi Arai
      • Natsumi Muto
      • Akari Hiraku
      • Kumiko Kato
      • Yasuyuki Kuwano
      • Hiroshi Maruyama
      • Masahiko Nakamura
      • Noriyuki Iwabuchi
      • Manabu Nakano
      • Toshitaka Odamaki
      • Miyuki Tanaka

    • PubMed: 39519413
    • DOI: 10.3390/nu16213580

    3 Insights on

    • Increased Bifidobacterium Levels in Feces
    • Increased Levels of Beneficial Metabolites
    • Modulated Gut Microbiome Composition

    • High evidence
    • Rigorous Journal

  • Bifidobacterium lactis-Derived Vesicles Attenuate Hippocampal Neuroinflammation by Targeting IL-33 to Regulate FoxO6/P53 Signaling.

    • 2024-10-22
    • Nutrients 16(21)
    • • Xiaoyu Du
      • Ming Zhang
      • Ran Wang
      • Zhaozhong Zeng
      • Wen Zhao
      • Bing Fang
      • Hanglian Lan
      • Weilian Hung
      • Haina Gao

    • PubMed: 39519420
    • DOI: 10.3390/nu16213586

    4 Insights on

    • Reduced Pro-Inflammatory Cytokines
    • Reduced Neuroinflammation
    • Reduced Oxidative Stress
    • Increased Neuronal Cell Survival

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Effectiveness of the Application of Lanolin, Aloe Vera, and Peppermint on Nipple Pain and Nipple Trauma in Lactating Mothers: A Systematic Review and Meta-Analysis.

    • 2024-10-22
    • Meta-Analysis · n = 495
    • Maternal and child health journal 28(12)
    • • Asha P Shetty
      • Kurvatteppa Halemani
      • Alwin Issac
      • Latha Thimmappa
      • Y N Shashidhara
      • Edlin Mathias
      • Sanjay Dhiraaj
      • K Radha
      • Prabhaker Mishra
      • Auchitya Sharma

    • PubMed: 39436586
    • DOI: 10.1007/s10995-024-04006-1

    2 Insights on

    • Reduced Nipple Trauma
    • Reduced Nipple Pain

    • High evidence

  • Broad-spectrum antimicrobial activities of a food fermentate of Aspergillus oryzae.

    • 2024-10-22
    • Microbiology spectrum 12(12)
    • • Dasol Choi
      • Ahmad F Alshannaq
      • Yohan Bok
      • Jae-Hyuk Yu

    • PubMed: 39436123
    • DOI: 10.1128/spectrum.01854-24

    1 Insight on

    • Disrupted Microbial Cell Membrane Integrity

    • Low evidence

  • Probiotic Potential in Irritable Bowel Syndrome and Inflammatory Bowel Disease: A Comprehensive Systematic Review.

    • 2024-10-22
    • Review · n = 675
    • Cureus 16(10)
    • • Anura Manandhar
      • Ghadeer Sabir
      • Hala A Abdelhady
      • Adoum Oumar Abakar
      • Ravindra Reddy Gangavarapu
      • Sayed A Mahmud
      • Iana Malasevskaia

    • PubMed: 39575029
    • DOI: 10.7759/cureus.72089

    2 Insights on

    • Improved Irritable Bowel Syndrome Symptoms
    • Improved Ulcerative Colitis

    • High evidence
• October 23

  • Characterization of a Bifidobacterium animalis subsp. lactis reference strain based on ecology and transcriptomics.

    • 2024-10-23
    • Applied and environmental microbiology 90(10)
    • • Gabriele Andrea Lugli
      • Chiara Argentini
      • Chiara Tarracchini
      • Leonardo Mancabelli
      • Alice Viappiani
      • Rosaria Anzalone
      • Leonora Angelini
      • Giulia Alessandri
      • Giulia Longhi
      • Massimiliano G Bianchi
      • Giuseppe Taurino
      • Ovidio Bussolati
      • Christian Milani
      • Francesca Turroni
      • Marco Ventura

    • PubMed: 39235395
    • DOI: 10.1128/aem.01080-24

    1 Insight on

    • Improved Niche Colonization

    • Low evidence
    • Rigorous Journal

  • Probiotics and Prebiotics for the Treatment of Irritable Bowel Syndrome-A Narrative Review.

    • 2024-10-23
    • Review
    • Journal of clinical medicine 13(21)
    • • Carolina Marques Lopes
      • Cristina Sofia de Jesus Monteiro
      • Ana Paula Duarte
      • Jorge Luiz Dos Santos

    • PubMed: 39518476
    • DOI: 10.3390/jcm13216337

    1 Insight on

    • Improved Irritable Bowel Syndrome Symptoms

    • Low evidence

  • The Effects of Bitter Melon ( Mormordica charantia ) on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    • 2024-10-23
    • Meta-Analysis · n = 423
    • Phytotherapy research : PTR 38(12)
    • • Mohammad Reza Amini
      • Niloufar Rasaei
      • Moharam Jalalzadeh
      • Sanaz Pourreza
      • Azita Hekmatdoost

    • PubMed: 39444254
    • DOI: 10.1002/ptr.8357

    4 Insights on

    • Reduced Triglyceride Levels
    • Reduced LDL Cholesterol
    • Reduced Blood Cholesterol
    • Increased High-Density Lipoprotein Cholesterol

    • High evidence
• October 24

  • Examining the Effect of Peppermint Oil on Postoperative Nausea After Cervical Surgery.

    • 2024-10-24
    • RCT
    • The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 56(6)
    • • Nurdan Cetin
      • Gulsah Kose
      • Aykut Gokbel

    • PubMed: 39447066
    • DOI: 10.1097/jnn.0000000000000790

    5 Insights on

    • Reduced Systolic Blood Pressure
    • Reduced Nausea
    • Reduced Vomiting
    • Reduced Nausea Severity
    • Reduced Antiemetic Medication Use

    • High evidence
• October 25

  • Consumption of a Probiotic Blend with Vitamin D Improves Immunity, Redox, and Inflammatory State, Decreasing the Rate of Aging-A Pilot Study.

    • 2024-10-25
    • Clinical Trial · n = 14
    • Biomolecules 14(11)
    • • Judith Félix
      • Adriana Baca
      • Luz Taboada
      • Guillermo Álvarez-Calatayud
      • Mónica De la Fuente

    • PubMed: 39595538
    • DOI: 10.3390/biom14111360

    4 Insights on

    • Improved Immune Function
    • Reduced Inflammation
    • Reduced Oxidative Stress
    • Reduced Biological Age

    • Moderate evidence
• October 26

  • Efficacy of Streptococcus salivarius Blis K12 in the Prevention of Upper Respiratory Tract Infections in Physically Active Individuals: A Randomized Controlled Trial.

    • 2024-10-26
    • RCT · n = 112
    • Microorganisms 12(11)
    • • Alexander Bertuccioli
      • Marco Cardinali
      • Matteo Micucci
      • Marco Bruno Luigi Rocchi
      • Chiara Maria Palazzi
      • Giordano Bruno Zonzini
      • Giosuè Annibalini
      • Annalisa Belli
      • Davide Sisti

    • PubMed: 39597553
    • DOI: 10.3390/microorganisms12112164

    5 Insights on

    • Reduced Upper Respiratory Infections
    • Reduced Incidence of Upper Respiratory Tract Infections
    • Reduced Upper Respiratory Tract Infection Severity
    • Reduced Upper Respiratory Tract Infection Symptoms
    • Increased Days Without Illness

    • High evidence
• October 27

  • The Effect of Algae Supplementation on Anthropometric Indices in Adults: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    • 2024-10-27
    • Meta-Analysis
    • Nutrition reviews 83(3)
    • • Shervin Kazeminejad
      • Pishva Arzhang
      • Mohammadreza Moradi Baniasadi
      • Alireza Hatami
      • Leila Azadbakht

    • PubMed: 39461896
    • DOI: 10.1093/nutrit/nuae151

    6 Insights on

    • Reduced Waist Circumference
    • Reduced Body Mass Index
    • Reduced Body Weight
    • Reduced Body Fat Percentage
    • Reduced Hip Circumference
    • Reduced Body Fat Mass

    • High evidence
• October 28

  • Lactiplantibacillus plantarum NMGL2 exopolysaccharide ameliorates DSS-induced IBD in mice mainly by regulation of intestinal tight junction and NF-κB p65 protein expression.

    • 2024-10-28
    • Frontiers in microbiology 15
    • • Zengjia Zhou
      • Min Zhang
      • Mengke Yao
      • Jasra Naseeb
      • Abid Sarwar
      • Zhennai Yang
      • Tariq Aziz
      • Majid Alhomrani
      • Walaa F Alsanie
      • Abdulhakeem S Alamri

    • PubMed: 39529667
    • DOI: 10.3389/fmicb.2024.1491727

    4 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Inflammation
    • Reduced Oxidative Stress
    • Reduced Inflammatory Bowel Disease Symptoms

    • Low evidence
• October 29

  • Vitamin E and Non-alcoholic Fatty Liver Disease: Investigating the Evidence Through a Systematic Review.

    • 2024-10-29
    • Review · n = 11
    • Cureus 16(10)
    • • Mahlet Abera
      • Suchith B Suresh
      • Aparna Malireddi
      • Sruthi Boddeti
      • Khutaija Noor
      • Mehwish Ansar
      • Iana Malasevskaia

    • PubMed: 39610563
    • DOI: 10.7759/cureus.72596

    3 Insights on

    • Improved Adiposity Biomarkers
    • Reduced Inflammation
    • Reduced Serum Aminotransferase Level

    • Low evidence

  • Flaxseed Lowers Blood Pressure in Hypertensive Subjects: A Meta-Analysis of Randomized Controlled Trials.

    • 2024-10-29
    • Review
    • Clinical nutrition research 13(4)
    • • Ezatollah Fazeli Moghadam
      • Leili Khaghani
      • Parivash Shekarchizadeh-Esfahani

    • PubMed: 39526211
    • DOI: 10.7762/cnr.2024.13.4.295

    2 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Systolic Blood Pressure

    • Low evidence

  • Effects of Chicken Egg Powder, Bovine Colostrum, and Combination Therapy for the Treatment of Gastrointestinal Disorders.

    • 2024-10-29
    • Review
    • Nutrients 16(21)
    • • Raymond John Playford

    • PubMed: 39519517
    • DOI: 10.3390/nu16213684

    4 Insights on

    • Improved Growth
    • Improved Gut Protection
    • Improved Gut Repair
    • Reduced Gut Damage

    • Moderate evidence
    • Rigorous Journal
• October 31

  • Astaxanthin improves assisted reproductive technology outcomes in poor ovarian responders through alleviating oxidative stress, inflammation, and apoptosis: a randomized clinical trial.

    • 2024-10-31
    • RCT
    • Journal of ovarian research 17(1)
    • • Anahid Shafie
      • Ashraf Aleyasin
      • Mojtaba Saffari
      • Mojtaba Saedi
      • Sahar Rostami
      • Saeede Rezayi
      • Seyed Danial Mohammadi
      • Fardin Amidi

    • PubMed: 39482765
    • DOI: 10.1186/s13048-024-01537-7

    12 Insights on

    • Reduced Interleukin-6 Levels
    • Increased Antioxidant Enzyme Levels
    • Reduced Interleukin-1β Levels
    • Increased Superoxide Dismutase Levels
    • Increased Total Serum Antioxidant Capacity
    • Reduced Malondialdehyde Level
    • Increased Retrieved Oocyte Count
    • Increased MII Oocyte Count
    • Increased Number of Frozen Embryo
    • Increased High-Quality Embryo Count
    • Reduced Vascular Endothelial Growth Factor Level
    • Reduced Follicular Fluid Cell-Free DNA Level

    • High evidence

  • Effects of Limosilactobacillus reuteri DSM 17938 in neonates exposed to antibiotics: a randomised controlled trial.

    • 2024-10-31
    • RCT
    • Beneficial microbes 16(2)
    • • J Lozar Krivec
      • P Bratina
      • A Valcl
      • K Lozar Manfreda
      • A Petrovčič
      • E Benedik
      • T Obermajer
      • B Bogovič Matijašić
      • U Šetina
      • M Rupnik
      • A Mahnič
      • D Paro-Panjan

    • PubMed: 39486439
    • DOI: 10.1163/18762891-bja00049

    3 Insights on

    • Reduced Crying Duration
    • Reduced Functional Gastrointestinal Disorder
    • Increased Sleep Duration

    • High evidence
    • Rigorous Journal

  • Longitudinal Fecal Microbiota Profiles in A Cohort of Non-Hospitalized Adolescents and Young Adults with COVID-19: Associations with SARS-CoV-2 Status and Long-Term Fatigue.

    • 2024-10-31
    • Observational
    • Pathogens (Basel, Switzerland) 13(11)
    • • Christine Olbjørn
      • Milada Hagen
      • Aina Elisabeth Fossum Moen
      • Lise Beier Havdal
      • Silke Lauren Sommen
      • Lise Lund Berven
      • Espen Thiis-Evensen
      • Tonje Stiansen-Sonerud
      • Joel Selvakumar
      • Vegard Bruun Bratholm Wyller

    • PubMed: 39599506
    • DOI: 10.3390/pathogens13110953

    2 Insights on

    • Persistent Fatigue
    • Post-COVID Condition

    • Low evidence
• Undated – 8 supplement studies

  • Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 promote infected wound healing via regulation of the wound microenvironment.

    • 2024-10
    • Microbial biotechnology 17(10)
    • • Zhe Yin
      • Yilin Wang
      • Xiaojuan Feng
      • Changqing Liu
      • Xiaoyang Guan
      • Shuyan Liu
      • Zhanyi Long
      • Zhonghua Miao
      • Fang He
      • Ruyue Cheng
      • Yanting Han
      • Ka Li

    • PubMed: 39422648
    • DOI: 10.1111/1751-7915.70031

    4 Insights on

    • Improved Wound Healing
    • Reduced Inflammation
    • Reduced Pathogenic Bacterial Abundance
    • Reduced Inflammation Around Wounds

    • Low evidence
    • Animal Study

  • Effects of breast-fed infants-derived Limosilactobacillus reuteri and Bifidobacterium breve ameliorate DSS-induced colitis in mice.

    • 2024-10
    • iScience 27(10)
    • • Zhipeng Huang
      • Bingdong Liu
      • Lanlin Xiao
      • Miaomiao Liao
      • Liujing Huang
      • Xiaogan Zhao
      • Kai Ma
      • Runxin Wang
      • Feng Ji
      • Wei Li
      • Liping Huang
      • Liwei Xie

    • PubMed: 39351200
    • DOI: 10.1016/j.isci.2024.110902

    1 Insight on

    • Improved Colitis Symptoms

    • Low evidence

  • Effects of soy protein-rich meals on muscle health of older adults in long-term care: A randomized clinical trial.

    • 2024-10
    • RCT · n = 84
    • Nutrition (Burbank, Los Angeles County, Calif.) 126
    • • Wuke Yuan
      • Min Chen
      • Yanqiu Chen
      • Danfeng Xu
      • Zhen Li
      • Huijing Bai
      • Qi Xu
      • Yuanrong Jiang
      • Jie Gu
      • Shengqi Li
      • Chenxi Su
      • Lili Gu
      • Jiaxin Fang
      • Xinyao Zhu
      • Jianqin Sun
      • Jie Chen

    • PubMed: 39003895
    • DOI: 10.1016/j.nut.2024.112507

    5 Insights on

    • Increased Skeletal Muscle Mass
    • Increased Lean Body Mass
    • Increased Appendicular Skeletal Muscle Mass
    • Maintained Calf Circumference
    • Improved 6-Meter Walk Performance

    • High evidence

  • The Role of Microbiome and Probiotics in Chemo-Radiotherapy-Induced Diarrhea: A Narrative Review of the Current Evidence.

    • 2024-10
    • Review
    • Cancer reports (Hoboken, N.J.) 7(10)
    • • Sanaz Khorashadizadeh
      • Sara Abbasifar
      • Mohammad Yousefi
      • Farzad Fayedeh
      • AmirAli Moodi Ghalibaf

    • PubMed: 39410854
    • DOI: 10.1002/cnr2.70029

    4 Insights on

    • Reduced Intestinal Inflammation
    • Reduced Diarrhea
    • Improved Intestinal Cell Integrity
    • Reduced Chemotherapy-Induced Diarrhea

    • Low evidence

  • Lactobacillus gasseri BNR17 and Limosilactobacillus fermentum ABF21069 Ameliorate High Sucrose-Induced Obesity and Fatty Liver via Exopolysaccharide Production and β-oxidation.

    • 2024-10
    • Journal of microbiology (Seoul, Korea) 62(10)
    • • Yu Mi Jo
      • Yoon Ji Son
      • Seul-Ah Kim
      • Gyu Min Lee
      • Chang Won Ahn
      • Han-Oh Park
      • Ji-Hyun Yun

    • PubMed: 39417925
    • DOI: 10.1007/s12275-024-00173-6

    3 Insights on

    • Improved Lipid Metabolism
    • Reduced Liver Fat
    • Increased Exopolysaccharide Production

    • Low evidence
    • Animal Study

  • Maternal gut Bifidobacterium breve modifies fetal brain metabolism in germ-free mice.

    • 2024-10
    • Molecular metabolism 88
    • • Jorge Lopez-Tello
      • Raymond Kiu
      • Zoe Schofield
      • Cindy X W Zhang
      • Douwe van Sinderen
      • Gwénaëlle Le Gall
      • Lindsay J Hall
      • Amanda N Sferruzzi-Perri

    • PubMed: 39127167
    • DOI: 10.1016/j.molmet.2024.102004

    1 Insight on

    • Modified Fetal Brain Metabolism

    • Low evidence
    • Animal Study

  • The effect of Nigella sativa supplementation on glycemic status in adults: An updated systematic review and meta-analysis of randomized controlled trials.

    • 2024-10
    • Meta-Analysis · n = 30
    • Prostaglandins & other lipid mediators 174
    • • Shabnam Shirvani
      • Maryam Falahatzadeh
      • Elham Oveili
      • Mehrdad Jamali
      • Pedram Pam
      • Maryam Parang
      • Mehrnaz Shakarami

    • PubMed: 39181437
    • DOI: 10.1016/j.prostaglandins.2024.106885

    4 Insights on

    • Improved Insulin Levels
    • Reduced Hemoglobin A1c
    • Reduced Fasting Blood Glucose Levels
    • Reduced HOMA-IR

    • High evidence

  • The effect of vitamin D2 on lipid profile, anthropometric indices, blood pressure, and inflammatory and glycemic biomarkers in humans: A systematic review and meta-analysis of randomized controlled trials.

    • 2024-10
    • Meta-Analysis
    • Prostaglandins & other lipid mediators 174
    • • Zhihong Zhou
      • Jiyuan Liu
      • Hui Zhang
      • Kousalya Prabahar
      • Benjamin Hernández-Wolters
      • Yuanhong Yuan

    • PubMed: 39154789
    • DOI: 10.1016/j.prostaglandins.2024.106883

    12 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Waist Circumference
    • Reduced Body Mass Index
    • Reduced Systolic Blood Pressure
    • Reduced Triglyceride Levels
    • Increased HDL Cholesterol Levels
    • Reduced LDL Cholesterol
    • Reduced Hemoglobin A1c
    • Reduced Blood Cholesterol
    • Reduced C-Reactive Protein Levels
    • Reduced Fasting Blood Glucose Levels
    • Reduced HOMA-IR

    • High evidence