June 2025 Supplement Research Papers

• June 1

  • Effects of lactic acid bacteria isolated from dairy products on lipid pattern of rats fed with a high fat diet.

    • 2025-06-01
    • n = 49
    • Iranian journal of microbiology 17(3)
    • • Sahar Fouladi
      • Elham Moazamian

    • PubMed: 40612728
    • DOI: 10.18502/ijm.v17i3.18826

    8 Insights on

    • Reduced Blood Lipid Levels
    • Reduced Liver Enzyme Levels
    • Reduced Liver Fat
    • Reduced Liver Fat Deposition
    • Reduced Weight Gain
    • Improved Liver Enzyme Function
    • Reduced Serum Lipid Levels
    • Reduced Adipocyte Diameter

    • Low evidence
• June 2

  • Microbiome Engineering for Biotherapeutic in Alzheimer's Disease Through the Gut-Brain Axis: Potentials and Limitations.

    • 2025-06-02
    • Review
    • International journal of molecular sciences 26(11)
    • • Editha Renesteen
      • Jacqueline L Boyajian
      • Paromita Islam
      • Amal Kassab
      • Ahmed Abosalha
      • Stephanie Makhlouf
      • Madison Santos
      • Hongmei Chen
      • Cedrique Shum-Tim
      • Satya Prakash

    • PubMed: 40508160
    • DOI: 10.3390/ijms26115351

    4 Insights on

    • Improved Cognitive Function
    • Improved Gut Health
    • Reduced Inflammation
    • Normalized Neurotransmitter Levels

    • Moderate evidence
    • Rigorous Journal
• June 3

  • Lactobacillus GG and other probiotics in pediatric food allergy treatment: a network meta-analysis.

    • 2025-06-03
    • Systematic Review · n = 502
    • Frontiers in nutrition 12
    • • Li Xiaohua
      • Du Yiting
      • Li Qin
      • Zhai Yang
      • Wu Shumao
      • Peng Li
      • Pan Yi
      • Chen Lingmei
      • Liao Wenge
      • Li Maoxia

    • PubMed: 40529417
    • DOI: 10.3389/fnut.2025.1565436

    7 Insights on

    • Improved Quality of Life
    • Improved Atopic Dermatitis Severity
    • Improved Immune Regulation
    • Reduced IgE Levels
    • Improved Allergic Symptoms
    • Reduced Immunoglobulin E Level
    • Reduced SCORAD Score

    • High evidence

  • Oral administration of Lactiplantibacillus plantarum GKK1 ameliorates atopic dermatitis in a mouse model.

    • 2025-06-03
    • Frontiers in microbiology 16
    • • Tzu-Chun Lin
      • Yu-Chieh Wu
      • You-Shan Tsai
      • Shih-Wei Lin
      • Chin-Chu Chen
      • Ming-Ju Chen
      • Yen-Po Chen

    • PubMed: 40529585
    • DOI: 10.3389/fmicb.2025.1566594

    6 Insights on

    • Improved Gut Microbiota
    • Reduced Pro-Inflammatory Cytokines
    • Improved Atopic Dermatitis Symptoms
    • Modulated Immune Response
    • Reduced Atopic Dermatitis Severity
    • Reduced Skin Inflammation

    • Low evidence

  • Incorporating Postbiotics into Intervention for Managing Obesity.

    • 2025-06-03
    • Review
    • International journal of molecular sciences 26(11)
    • • Emília Hijová
      • Izabela Bertková
      • Jana Štofilová

    • PubMed: 40508171
    • DOI: 10.3390/ijms26115362

    1 Insight on

    • Improved Weight Management

    • Moderate evidence
    • Rigorous Journal
• June 5

  • Impacts of Milk Protein Supplementation on Lipid Profile, Blood Pressure, Oxidative Stress, and Liver Enzymes: A Systematic Review and Meta-analysis.

    • 2025-06-05
    • Meta-Analysis
    • Nutrition reviews 84(4)
    • • Shooka Mohammadi
      • Damoon Ashtary-Larky
      • Mahya Beyki
      • Narges Kouhi Sough
      • Navid Alaghemand
      • Niusha Amirani
      • Hossein Salehi Omran
      • Sina Dolatshahi
      • Omid Asbaghi

    • PubMed: 40471664
    • DOI: 10.1093/nutrit/nuaf068

    2 Insights on

    • Reduced Triglyceride Levels
    • Reduced Total Cholesterol

    • High evidence

  • An In Vitro Gut-Liver-Adipose Axis Model to Evaluate the Anti-Obesity Potential of a Novel Probiotic-Polycosanol Combination.

    • 2025-06-05
    • Foods (Basel, Switzerland) 14(11)
    • • Simone Mulè
      • Rebecca Galla
      • Francesca Parini
      • Mattia Botta
      • Sara Ferrari
      • Francesca Uberti

    • PubMed: 40509530
    • DOI: 10.3390/foods14112003

    6 Insights on

    • Reduced Liver Lipid Accumulation
    • Improved Gut Integrity
    • Reduced Oxidative Stress
    • Reduced Hepatic Lipid Accumulation
    • Improved Thermogenesis
    • Increased Thermogenic Adipocyte Activity

    • Low evidence

  • Vitamin C as an Adjuvant Analgesic Therapy in Postoperative Pain Management.

    • 2025-06-05
    • Review · n = 14
    • Journal of clinical medicine 14(11)
    • • Wioletta Mędrzycka-Dąbrowska
      • Sandra Lange
      • Sebastian Dąbrowski
      • Klaudia Długoborska
      • Renata Piotrkowska

    • PubMed: 40507754
    • DOI: 10.3390/jcm14113994

    2 Insights on

    • Reduced Pain Intensity
    • Reduced Opioid Consumption

    • Low evidence

  • The role of fermented foods in maternal health during pregnancy and infant health during the first 1,000 days of life.

    • 2025-06-05
    • Review
    • Frontiers in nutrition 12
    • • Arun Pandiyan
      • Manoj Gurung
      • Bharath Kumar Mulakala
      • Sathish Kumar Ponniah
      • Laxmi Yeruva

    • PubMed: 40538587
    • DOI: 10.3389/fnut.2025.1581723

    2 Insights on

    • Improved Immune Function
    • Improved Brain Health

    • Low evidence
• June 6

  • Bifidobacterium breve BBr60 Enhances SCFA Levels and Restores NLRP3/NLRP6 Balance in the Gut to Improve Motor Deficits in PD Mice.

    • 2025-06-06
    • Probiotics and antimicrobial proteins 18(1)
    • • P P An
      • X Y Liang
      • X Y Yao
      • Z H Liao
      • Y C Tang
      • N Cao
      • Z Wang
      • W Wang
      • H Y Niu
      • C X Tang
      • J Chen

    • PubMed: 40478433
    • DOI: 10.1007/s12602-025-10576-5

    3 Insights on

    • Reduced Neuroinflammation
    • Increased Short-Chain Fatty Acid Production
    • Improved Motor Function

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Bifidobacterium longum subsp. longum dipro-O: a potential therapeutic agent for ameliorating metabolic disorders in high-fat diet-induced obesity mouse model.

    • 2025-06-06
    • Frontiers in endocrinology 16
    • • Ning Xu
      • Jiang Luo
      • Weiyang Chen
      • Weiwei Xiang
      • Yue Zhai
      • Wei Jiang
      • Junlin Wu
      • Yanqing Hao
      • Meiru Chen
      • Qinghua Yu

    • PubMed: 40547525
    • DOI: 10.3389/fendo.2025.1519058

    5 Insights on

    • Improved Gut Homeostasis
    • Reduced Liver Fat
    • Reduced Weight Gain
    • Improved Blood Glucose Control
    • Improved Blood Lipid Profile

    • Low evidence
    • Animal Study

  • Dose-dependent effect of coconut oil supplementation on obesity indices: a systematic review and dose-response meta-analysis of clinical trials.

    • 2025-06-06
    • Systematic Review · n = 620
    • BMC nutrition 11(1)
    • • Zahra Gaeini
      • Zahra Bahadoran
      • Hanieh Malmir
      • Parvin Mirmiran

    • PubMed: 40481535
    • DOI: 10.1186/s40795-025-01090-6

    3 Insights on

    • Reduced Waist Circumference
    • Reduced Body Mass Index
    • Reduced Body Weight

    • High evidence
• June 7

  • Efficacy of Lactobacillus reuteri DSM 17938 in Thai children with acute gastroenteritis and normal or mild dehydration in an outpatient setting: a randomized controlled trial.

    • 2025-06-07
    • RCT · n = 48
    • Journal of tropical pediatrics 71(4)
    • • Lakkana Rerksuppaphol
      • Sanguansak Rerksuppaphol

    • PubMed: 40618229
    • DOI: 10.1093/tropej/fmaf027

    5 Insights on

    • Reduced Duration of Diarrhea
    • Reduced Diarrhea Rate
    • Reduced Recovery Time for Diarrhea
    • No Serious Adverse Effects
    • Improved Recovery from Diarrhea

    • High evidence

  • Fava bean and buckwheat are sustainable food sources which support satiety and beneficially modulate several biomarkers, bacteria and metabolites associated with human health.

    • 2025-06-07
    • RCT · n = 14
    • European journal of nutrition 64(5)
    • • Madalina Neacsu
      • Marietta Sayegh
      • Nicholas J Vaughan
      • Gary J Duncan
      • Louise Cantlay
      • Susan Anderson
      • Donna Henderson
      • Claire Fyfe
      • Freda Farquharson
      • Salifu Saibu
      • Graham Horgan
      • Petra Louis
      • Alexandra M Johnstone
      • Wendy R Russell

    • PubMed: 40481954
    • DOI: 10.1007/s00394-025-03726-6

    6 Insights on

    • Improved Insulin Levels
    • Improved Fasting Plasma Glucose
    • Reduced Homocysteine Level
    • Increased Homocysteine Level
    • Reduced Plasma Urea Level
    • Reduced Subjective Hunger

    • High evidence
    • Rigorous Journal
• June 9

  • Cholecalciferol (vitamin D3): efficacy, safety, and implications in public health.

    • 2025-06-09
    • Review
    • Frontiers in nutrition 12
    • • Esteban Ortiz-Prado
      • Jorge Vasconez-Gonzalez
      • Juan S Izquierdo-Condoy
      • Isaac A Suárez-Sangucho
      • José Guillermo Prieto-Marín
      • Karen Bereniss Villarreal-Burbano
      • Mateo Alejandro Barriga-Collantes
      • John Alexander Altamirano-Castillo
      • Domenic Anahi Borja-Mendoza
      • Jean Carlo Pazmiño-Almeida
      • María Paz Cadena-Padilla

    • PubMed: 40551736
    • DOI: 10.3389/fnut.2025.1579957

    7 Insights on

    • Reduced Inflammation
    • Improved Immune Homeostasis
    • Reduced Cancer Incidence
    • Improved Glycemia
    • Increased Bone Mineral Density
    • Reduced Cardiovascular Event
    • Reduced Cognitive Decline

    • Low evidence

  • Glucose Parameters, Inflammation Markers, and Gut Microbiota Changes of Gut Microbiome-Targeted Therapies in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    • 2025-06-09
    • Meta-Analysis · n = 3,390
    • The Journal of clinical endocrinology and metabolism 110(10)
    • • Xin Zhou
      • Wenbin Zheng
      • Wen Kong
      • Jiaoyue Zhang
      • Yunfei Liao
      • Jie Min
      • Tianshu Zeng

    • PubMed: 40489582
    • DOI: 10.1210/clinem/dgaf340

    5 Insights on

    • Improved Gut Microbiota
    • Increased Beneficial Gut Microbiota
    • Improved Glycemic Control
    • Reduced Inflammation
    • Improved Glycemia

    • High evidence

  • Is It Advisable to Use Probiotics Routinely After a Colonoscopy? A Rapid Comprehensive Review of the Evidence.

    • 2025-06-09
    • Review
    • Medical sciences (Basel, Switzerland) 13(2)
    • • Matteo Piciucchi
      • Alice Rossi
      • Alissa Satriano
      • Raffaele Manta

    • PubMed: 40559234
    • DOI: 10.3390/medsci13020076

    1 Insight on

    • Reduced Gastrointestinal Symptoms

    • Low evidence
• June 10

  • Evaluation of the Immunostimulant Effect of Microvesicles of Lactobacillus acidophilus Isolated from Wild Rats.

    • 2025-06-10
    • Microorganisms 13(6)
    • • Pamela I Pérez-Martínez
      • Viridiana Gutiérrez-Espinosa
      • Christian Ávalos-Gómez
      • Mireya De la Garza-Amaya
      • Alejandro Vargas-Ruíz
      • Rosa I Higuera-Piedrahita
      • Ernesto Marín-Flamand
      • Cristal D Lonngi-Sosa
      • Francisco R González-Díaz
      • Hugo Ramírez-Álvarez
      • Cynthia González-Ruíz

    • PubMed: 40572234
    • DOI: 10.3390/microorganisms13061341

    3 Insights on

    • Improved Immune Response
    • Reduced Larval Attachment to Intestinal Tissue
    • Reduced Parasite Larval Burden

    • Low evidence

  • Gut microbiota modulation and immunity enhancement by Bacillus amyloliquefaciens NL1.2: A fiber-degrading probiotic isolated from native Thai swine.

    • 2025-06-10
    • Veterinary world 18(6)
    • • Kittiya Khongkool
      • Malai Taweechotipatr
      • Sunchai Payungporn
      • Vorthon Sawaswong
      • Monthon Lertworapreecha

    • PubMed: 40689169
    • DOI: 10.14202/vetworld.2025.1487-1507

    3 Insights on

    • Improved Gut Microbiota Composition
    • Improved Intestinal Immune Response
    • No Observed Adverse Effects

    • Low evidence
• June 11

  • L-arginine role for stone lower ureter: A randomized controlled trial.

    • 2025-06-11
    • RCT · n = 162
    • Urolithiasis 53(1)
    • • Ahmed Mahmoud Mohammed Ahmed Elsherief
      • Ahmed Mahmoud Riyad
      • Emad Abdellah Ali
      • Amr Alam-Eldin Ahmed
      • Hassan Ali Gad
      • Ahmed Mamdouh Abd Elhameid

    • PubMed: 40498114
    • DOI: 10.1007/s00240-025-01768-3

    7 Insights on

    • Increased Spontaneous Stone Expulsion Rate
    • Reduced Stone Expulsion Time
    • Reduced Colic
    • Reduced Total Analgesic Dosage
    • Reduced Kidney Stone Density
    • Reduced Hydronephrosis
    • Improved Imaging Findings

    • High evidence
    • Large Human Trial
• June 12

  • Recent advances in therapeutic probiotics: insights from human trials.

    • 2025-06-12
    • Review
    • Clinical microbiology reviews 38(2)
    • • Mu-Yeol Cho
      • Je-Hyun Eom
      • Eun-Mi Choi
      • Seung-Jo Yang
      • Dahye Lee
      • Young Youn Kim
      • Hye-Sung Kim
      • Inseong Hwang

    • PubMed: 40261032
    • DOI: 10.1128/cmr.00240-24

    1 Insight on

    • Improved Gut Health

    • Low evidence

  • Nanoparticle-Driven Modulation of Mucosal Immunity and Interplay with the Microbiome.

    • 2025-06-12
    • Review
    • Journal of microbiology and biotechnology 35
    • • Won Jung
      • Young Min Son

    • PubMed: 40537897
    • DOI: 10.4014/jmb.2504.04033

    2 Insights on

    • Improved Gut Microbiota Balance
    • Improved Mucosal Barrier Function

    • Low evidence

  • Fermented Fruits, Vegetables, and Legumes in Metabolic Syndrome: From Traditional Use to Functional Foods and Medical Applications.

    • 2025-06-12
    • Review
    • Nutrients 17(12)
    • • Karolina Bernacka
      • Tomasz Sozański
      • Alicja Z Kucharska

    • PubMed: 40573100
    • DOI: 10.3390/nu17121989

    1 Insight on

    • Improved Metabolic Syndrome Biomarkers

    • Moderate evidence
    • Rigorous Journal

  • Draft genome of Lactobacillus amylovorus KSAU with probiotic potential isolated from the gastrointestinal tract of industrial pigs.

    • 2025-06-12
    • Microbiology resource announcements 14(6)
    • • Yuri A Lysenko
      • Alexander V Milovanov
      • Sergey V Kopyltsov
      • Dominika Gahurová
      • Anastasia V Elisiutikova

    • PubMed: 40396734
    • DOI: 10.1128/mra.00577-24

    1 Insight on

    • Improved Gut Health

    • Low evidence

  • Effects of Hawthorn Fruit Supplementation on Facial Skin Phenotypes and Leukocyte Telomere Length Stratified by TERT Polymorphisms.

    • 2025-06-12
    • RCT
    • Nutrients 17(12)
    • • Minju Kim
      • Inkyung Baik

    • PubMed: 40573097
    • DOI: 10.3390/nu17121983

    6 Insights on

    • Improved Facial Skin Hydration
    • Reduced Facial Skin Pigmentation
    • Reduced Facial Skin Pores
    • Reduced Facial Skin Wrinkles
    • Improved Facial Skin Elasticity
    • Changed Leukocyte Telomere Length

    • High evidence
    • Rigorous Journal
• June 14

  • Heat-killed Lactococcus lactis subsp. lactis L8 ameliorates dextran sulfate sodium-induced colitis in mice.

    • 2025-06-14
    • Journal of clinical biochemistry and nutrition 76(3)
    • • Shogo Kawaguchi
      • Daisuke Chinda
      • Shinji Ota
      • Akio Tonouchi
      • Hayato Maeda
      • Kazuhide Miura
      • Go Soma
      • Hiroto Hiraga
      • Kayo Ueno
      • Takenori Niioka
      • Mayuki Tachizaki
      • Kazuhiko Seya
      • Tadaatsu Imaizumi
      • Shinsaku Fukuda
      • Hirotake Sakuraba

    • PubMed: 40510387
    • DOI: 10.3164/jcbn.24-194

    3 Insights on

    • Reduced Colitis Severity
    • Reduced Colonic Inflammation
    • Reduced Intestinal Inflammation

    • Low evidence
• June 16

  • Probiotics and Cancer: Mechanistic Insights and Organ-Specific Impact.

    • 2025-06-16
    • Review
    • Biomolecules 15(6)
    • • Md Faruque Ahmad
      • Fakhruddin Ali Ahmad
      • Abdulrahman A Alsayegh
      • Md Zeyaullah
      • Ahmad O Babalghith
      • Hani Faidah
      • Faiyaz Ahmed
      • Anjum Khanam
      • Boshra Mozaffar
      • Nahla Kambal
      • Farkad Bantun

    • PubMed: 40563519
    • DOI: 10.3390/biom15060879

    2 Insights on

    • Cancer-Related Supportive Effects
    • Reduced Chemotherapy Side Effects

    • Low evidence
• June 17

  • Rewiring Mood: Precision Psychobiotics as Adjunct or Stand-Alone Therapy in Depression Using Insights from 19 Randomized Controlled Trials in Adults.

    • 2025-06-17
    • Review
    • Nutrients 17(12)
    • • Alexandra-Eleftheria Menni
      • Helen Theodorou
      • Georgios Tzikos
      • Ioannis M Theodorou
      • Eleni Semertzidou
      • Veroniki Stelmach
      • Anne D Shrewsbury
      • George Stavrou
      • Katerina Kotzampassi

    • PubMed: 40573133
    • DOI: 10.3390/nu17122022

    4 Insights on

    • Reduced Depression Symptoms
    • Improved Depressive Symptoms
    • Improved Depression Status
    • Improved Antidepressant Support

    • Moderate evidence
    • Rigorous Journal

  • The role of probiotics in promoting systemic immune tolerance in systemic lupus erythematosus.

    • 2025-06-17
    • Review
    • Gut pathogens 17(1)
    • • Asma'a H Mohamed
      • Alaa Shafie
      • Rithab Ibrahim Al-Samawi
      • Mohammad Chand Jamali
      • Amal Adnan Ashour
      • Mohammed Fareed Felemban
      • Ali Alqarni
      • Irshad Ahmad
      • Nasrin Mansuri
      • Fuzail Ahmad
      • Adil Abdelrahim Mohammed Yousif

    • PubMed: 40528248
    • DOI: 10.1186/s13099-025-00702-7

    1 Insight on

    • Modulated Immune Tolerance

    • Low evidence
• June 19

  • Gut Microbiome Engineering for Diabetic Kidney Disease Prevention: A Lactobacillus rhamnosus GG Intervention Study.

    • 2025-06-19
    • Observational
    • Biology 14(6)
    • • Alaa Talal Qumsani

    • PubMed: 40563973
    • DOI: 10.3390/biology14060723

    4 Insights on

    • Improved Gut Microbiome Composition
    • Reduced Inflammation
    • Improved Kidney Function
    • Improved Glycemia

    • Low evidence

  • Developing Novel Plant-Based Probiotic Beverages: A Study on Viability and Physicochemical and Sensory Stability.

    • 2025-06-19
    • Foods (Basel, Switzerland) 14(12)
    • • Concetta Condurso
      • Maria Merlino
      • Anthea Miller
      • Ambra Rita Di Rosa
      • Francesca Accetta
      • Michelangelo Leonardi
      • Nicola Cicero
      • Teresa Gervasi

    • PubMed: 40565756
    • DOI: 10.3390/foods14122148

    1 Insight on

    • Improved Physicochemical Stability of Probiotic Beverages

    • Low evidence

  • Modulating oral microbiota ameliorates hypobaric hypoxia-induced anxiety- and depression-like behaviors in mice.

    • 2025-06-19
    • World journal of psychiatry 15(6)
    • • Wen-Yue Chang
      • Qiao-Zhen Qin
      • Xiao-Tong Li
      • Jia-Jing Wang
      • Yue Chen
      • Hua-Qiang Ruan
      • Yan-Nv Qu
      • Xiao-Xia Jiang
      • Hui-Xia He

    • PubMed: 40574783
    • DOI: 10.5498/wjp.v15.i6.104809

    2 Insights on

    • Reduced Anxiety-like Behavior
    • Reduced Depression-like Behavior

    • Low evidence

  • Effects of 12 Weeks of Chromium, Phyllanthus emblica Fruit Extract, and Shilajit Supplementation on Markers of Cardiometabolic Health, Fitness, and Weight Loss in Men and Women with Risk Factors to Metabolic Syndrome Initiating an Exercise and Diet Intervention: A Randomized Double-Blind, Placebo-Controlled Trial.

    • 2025-06-19
    • RCT
    • Nutrients 17(12)
    • • Victoria Martinez
      • Kay McAngus
      • Broderick L Dickerson
      • Megan Leonard
      • Elena Chavez
      • Jisun Chun
      • Megan Lewis
      • Dante Xing
      • Drew E Gonzalez
      • Choongsung Yoo
      • Joungbo Ko
      • Heather Rhodes
      • Hudson Lee
      • Ryan J Sowinski
      • Christopher J Rasmussen
      • Richard B Kreider

    • PubMed: 40573153
    • DOI: 10.3390/nu17122042

    2 Insights on

    • Improved Insulin Sensitivity
    • Improved Body Composition

    • High evidence
    • Rigorous Journal

  • Potential Role of Probiotic Strain Lactiplantibacillus plantarum in Control of Histamine Metabolism.

    • 2025-06-19
    • Biology 14(6)
    • • Gina Cavaliere
      • Egidia Costanzi
      • Beniamino Cenci-Goga
      • Marco Misuraca
      • Giovanna Traina

    • PubMed: 40563983
    • DOI: 10.3390/biology14060734

    1 Insight on

    • Increased Diamine Oxidase Secretion

    • Low evidence

  • L-Carnitine to Reduce Chemoradiotherapy-Induced Toxicity in Head and Neck Cancer: A Randomized Study.

    • 2025-06-19
    • RCT
    • Head & neck 47(11)
    • • Kumari Puja
      • Kamna Singh
      • Indira Yadav
      • Ashok Kumar Arya

    • PubMed: 40536003
    • DOI: 10.1002/hed.28221

    2 Insights on

    • Reduced Weight Loss
    • Reduced Fatigue

    • High evidence

  • Probiotification of a Tropical Juice Blend using Lactobacillus bulgaricus and Lactobacillus plantarum: A Preliminary Study.

    • 2025-06-19
    • Recent advances in food, nutrition & agriculture 16
    • • Carmencita Duberry
      • Rohanie Maharaj
      • Dimple Singh-Ackbarali
      • Vishal Ganessingh

    • PubMed: 40551693
    • DOI: 10.2174/012772574x394951250611073352

    1 Insight on

    • Improved Consumer Acceptance

    • Low evidence
• June 20

  • Immunomodulatory effect of allium sativum in type 2 diabetes mellitus.

    • 2025-06-20
    • Review
    • World journal of experimental medicine 15(2)
    • • Elva Manuela Mejía Delgado
      • Juan Eduardo Quiroz-Aldave
      • María Del Carmen Durand-Vásquez
      • Lea Noemí Aldave-Pita
      • Jenyfer María Fuentes-Mendoza
      • Luis Alberto Concepción-Urteaga
      • José Paz-Ibarra
      • Marcio José Concepción-Zavaleta

    • PubMed: 40546677
    • DOI: 10.5493/wjem.v15.i2.103481

    3 Insights on

    • Reduced Blood Pressure
    • Reduced Hemoglobin A1c
    • Reduced Oxidative Stress

    • Low evidence

  • Gut Microbiota and Liver Health: Meta-Analysis of Bifidobacterium-Containing Probiotics in NAFLD Management.

    • 2025-06-20
    • Meta-Analysis · n = 1,611
    • International journal of molecular sciences 26(13)
    • • Ko-Shih Chang
      • Wu-Hsien Kuo
      • Mu-Hsin Chang
      • Yao Hsiao
      • Ru-Yin Tsai

    • PubMed: 40649724
    • DOI: 10.3390/ijms26135944

    4 Insights on

    • Improved NAFLD
    • Reduced Inflammation
    • Improved Blood Lipid Profile
    • Improved Glycemia

    • High evidence
    • Rigorous Journal

  • Emerging Synbiotics Consisting of Catechin and Probiotic Bacteria: Exploring Aggregation, Adhesion, Antioxidant, and Anticancer Effects.

    • 2025-06-20
    • Probiotics and antimicrobial proteins 18(2)
    • • Sena Davran Bulut
      • Buse Nur Derebası
      • Sevilay Günay
      • Yavuz Erden
      • Hasan Ufuk Celebioglu
      • Mustafa Ümit Ünal

    • PubMed: 40537614
    • DOI: 10.1007/s12602-025-10631-1

    1 Insight on

    • Improved Antioxidant Activity

    • Low evidence
    • Rigorous Journal
• June 21

  • Lactobacillus amylovorus extracellular vesicles mitigate mammary gland ferroptosis via the gut-mammary gland axis.

    • 2025-06-21
    • NPJ biofilms and microbiomes 11(1)
    • • Qianzi Zhang
      • Dongpang Chen
      • Hanting Ding
      • Qihui Li
      • Siyu Yuan
      • Haobin Li
      • Wutai Guan
      • Shihai Zhang

    • PubMed: 40544167
    • DOI: 10.1038/s41522-025-00752-4

    5 Insights on

    • Improved Oxidative Stress Resistance
    • Reduced Cellular Damage
    • Improved Lactation Performance
    • Reduced Mammary Gland Ferroptosis
    • Reduced Lactation Decline

    • Low evidence
    • Animal Study

  • Effects of Creatine and β-Alanine Co-Supplementation on Exercise Performance and Body Composition: A Systematic Review.

    • 2025-06-21
    • Systematic Review · n = 263
    • Nutrients 17(13)
    • • Damoon Ashtary-Larky
      • Darren G Candow
      • Scott C Forbes
      • Leila Hajizadeh
      • Jose Antonio
      • Katsuhiko Suzuki

    • PubMed: 40647180
    • DOI: 10.3390/nu17132074

    8 Insights on

    • Reduced Body Fat Mass
    • Improved Anaerobic Power
    • Increased Lean Mass
    • Improved Time to Exhaustion
    • Improved Maximal Strength
    • Improved Repeated-Bout Performance
    • Improved VO2max
    • Improved Lactate Threshold

    • High evidence
    • Rigorous Journal

  • Does Protein Ingestion Timing Affect Exercise-Induced Adaptations? A Systematic Review with Meta-Analysis.

    • 2025-06-21
    • Meta-Analysis
    • Nutrients 17(13)
    • • Rafael A Casuso
      • Lennert Goossens

    • PubMed: 40647175
    • DOI: 10.3390/nu17132070

    3 Insights on

    • Improved Chest Press Strength
    • Improved Leg Press Strength
    • Improved Lean Body Mass

    • High evidence
    • Rigorous Journal

  • Growth-independent CLA production by Bifidobacterium breve JKL2022 and the potential transcriptional regulatory role of TetR in linoleic acid isomerase expression.

    • 2025-06-21
    • Microbial cell factories 24(1)
    • • Arxel G Elnar
      • Geun-Bae Kim

    • PubMed: 40544262
    • DOI: 10.1186/s12934-025-02766-1

    1 Insight on

    • Increased Conjugated Linoleic Acid Production

    • Low evidence
• June 22

  • Probiotics as Antioxidant Strategy for Managing Diabetes Mellitus and Its Complications.

    • 2025-06-22
    • Review
    • Antioxidants (Basel, Switzerland) 14(7)
    • • Max Denisson Maurício Viana
      • Sthefane Silva Santos
      • Anna Beatriz Oliveira Cruz
      • Maria Vitória Abreu Cardoso de Jesus
      • Pedro Santana Sales Lauria
      • Marvin Paulo Lins
      • Cristiane Flora Villarreal

    • PubMed: 40722870
    • DOI: 10.3390/antiox14070767

    3 Insights on

    • Reduced Oxidative Stress
    • Improved Glycemia
    • Reduced Diabetic Complications

    • Low evidence
• June 23

  • Recent Insights About Probiotics Related Pharmabiotics in Pharmacology: Prevention and Management of Diseases.

    • 2025-06-23
    • Review
    • Probiotics and antimicrobial proteins 17(4)
    • • Sena Davran Bulut
      • H Ali Döndaş
      • Hasan Ufuk Celebioglu
      • José M Sansano
      • Naciye Yaktubay Döndaş

    • PubMed: 40549339
    • DOI: 10.1007/s12602-025-10613-3

    1 Insight on

    • Improved Gut Health

    • Moderate evidence
    • Rigorous Journal

  • Polyphosphate from Lactic Acid Bacteria: A Functional Molecule for Food and Health Applications.

    • 2025-06-23
    • Review
    • Foods (Basel, Switzerland) 14(13)
    • • Daniela Corrales
      • Cristina Alcántara
      • Vicente Monedero
      • Manuel Zúñiga

    • PubMed: 40646963
    • DOI: 10.3390/foods14132211

    1 Insight on

    • Improved Intestinal Health

    • Low evidence
• June 24

  • The Role of Peptides in Nutrition: Insights into Metabolic, Musculoskeletal, and Behavioral Health: A Systematic Review.

    • 2025-06-24
    • Systematic Review
    • International journal of molecular sciences 26(13)
    • • Syed Khuram Zakir
      • Bilal Jawed
      • Jessica Elisabetta Esposito
      • Rimsha Kanwal
      • Riccardo Pulcini
      • Riccardo Martinotti
      • Edmondo Ceci
      • Matteo Botteghi
      • Francesco Gaudio
      • Elena Toniato
      • Stefano Martinotti

    • PubMed: 40649821
    • DOI: 10.3390/ijms26136043

    1 Insight on

    • Strengthened Musculoskeletal System

    • High evidence
    • Rigorous Journal
• June 25

  • The Anti-Inflammatory, Immunomodulatory, and Pro-Autophagy Activities of Probiotics for Colorectal Cancer Prevention and Treatment: A Narrative Review.

    • 2025-06-25
    • Review
    • Biomedicines 13(7)
    • • Beatrice Garavaglia
      • Letizia Vallino
      • Alessandra Ferraresi
      • Annalisa Visciglia
      • Angela Amoruso
      • Marco Pane
      • Camelia Munteanu
      • Ciro Isidoro

    • PubMed: 40722631
    • DOI: 10.3390/biomedicines13071554

    12 Insights on

    • Improved Intestinal Barrier Function
    • Improved Immune Function
    • Improved Immune Response
    • Improved Gut Integrity
    • Modulated Immune Response
    • Reduced Inflammation
    • Reduced Risk of Colorectal Cancer
    • Reduced Cancer-Related Inflammation
    • No Direct Health Outcome Reported
    • Reduced Urinary Tract Infection Symptoms
    • Increased Autophagy in Intestinal Epithelial Cells
    • Increased Autophagy

    • Low evidence

  • Postbiotics: An Alternative for Improving Health and Performance of Poultry Production.

    • 2025-06-25
    • Review
    • Microorganisms 13(7)
    • • Fabricia Roque
      • Mário Henrique Scapin Lopes
      • Paulo Raffi
      • Ricardo Oliveira
      • Márcio Caparroz
      • Giovana Longhini
      • Carlos Granghelli
      • Douglas Faria
      • Lúcio Araujo
      • Cristiane Araujo

    • PubMed: 40731983
    • DOI: 10.3390/microorganisms13071472

    3 Insights on

    • Improved Gastrointestinal Health
    • Improved Intestinal Health
    • Improved Productive Performance

    • Low evidence
• June 27

  • Analyzing potential of next-generation probiotics in cancer management.

    • 2025-06-27
    • Review
    • Molecular biology reports 52(1)
    • • Sheikh Saba Naz
      • Sidra Zafar

    • PubMed: 40579646
    • DOI: 10.1007/s11033-025-10737-3

    5 Insights on

    • Reduced Oxidative Stress
    • Reduced Inflammatory Response to Helicobacter pylori
    • Reduced Cancer Progression
    • Improved Chemotherapy Efficacy
    • Reduced Carcinogenesis

    • Low evidence

  • Psychobiotics in Depression: Sources, Metabolites, and Treatment-A Systematic Review.

    • 2025-06-27
    • Systematic Review
    • Nutrients 17(13)
    • • Angelika Śliwka
      • Magdalena Polak-Berecka
      • Kinga Zdybel
      • Agnieszka Zelek-Molik
      • Adam Waśko

    • PubMed: 40647242
    • DOI: 10.3390/nu17132139

    1 Insight on

    • Improved Depressive Symptoms

    • High evidence
    • Rigorous Journal

  • Effects of spirulina supplementation alone or with exercise on cardiometabolic health in overweight and obese adults: a systematic review and meta-analysis.

    • 2025-06-27
    • Systematic Review · n = 35
    • Frontiers in nutrition 12
    • • Zhenliang Fu
      • Shibiao Zhou
      • Xueyan Gu

    • PubMed: 40655486
    • DOI: 10.3389/fnut.2025.1624982

    9 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Body Weight
    • Reduced Triglyceride Levels
    • Reduced LDL Cholesterol
    • Improved Body Composition
    • Reduced Total Cholesterol
    • Increased HDL Cholesterol
    • Improved Glycemia
    • Increased High-Density Lipoprotein Cholesterol

    • High evidence
• June 28

  • Lactobacillus rhamnosus LRa05 Alleviates Constipation via Triaxial Modulation of Gut Motility, Microbiota Dynamics, and SCFA Metabolism.

    • 2025-06-28
    • Foods (Basel, Switzerland) 14(13)
    • • Jingxin Zhang
      • Qian Li
      • Shanshan Liu
      • Ning Wang
      • Yu Song
      • Tao Wu
      • Min Zhang

    • PubMed: 40647045
    • DOI: 10.3390/foods14132293

    4 Insights on

    • Improved Gut Microbiota Composition
    • Increased Short-Chain Fatty Acid Production
    • Improved Constipation
    • Increased Intestinal Motility

    • Low evidence

  • Effects of Garlic Supplementation on Cardiovascular Risk Factors in Adults: A Comprehensive Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    • 2025-06-28
    • Meta-Analysis · n = 7,137
    • Nutrition reviews 84(1)
    • • Vahideh Behrouz
      • Mehrnaz Zahroodi
      • Cain C T Clark
      • Elias Mir
      • Negin Atashi
      • Raha Rivaz

    • PubMed: 40580481
    • DOI: 10.1093/nutrit/nuaf090

    1 Insight on

    • Improved Insulin Sensitivity

    • High evidence
• June 29

  • Bifidobacterium bifidum G9-1 Survives in the Intestinal Environment and Influences the Gut Microbiota Despite the Presence of Antimicrobials.

    • 2025-06-29
    • Microbiology and immunology 69(9)
    • • Haruka Yokota
      • Yutaka Makizaki
      • Yoshiki Tanaka
      • Hiroshi Ohno

    • PubMed: 40582892
    • DOI: 10.1111/1348-0421.13230

    2 Insights on

    • Reduced Incidence of Antibiotic-Associated Diarrhea
    • Enhanced Gut Colonization

    • Low evidence
    • Animal Study
• June 30

  • In vitro screening of angiotensin converting enzyme and hydroxymethylglutaryl-coenzyme A reductase inhibitory activities in lactic acid bacteria and yeasts isolated from fermented sorghum gruels.

    • 2025-06-30
    • Review
    • Biotechnologia 106(2)
    • • Praise Temilade Ozabor
      • Johnson Olaleye Oladele
      • Ilesanmi Festus Fadahunsi

    • PubMed: 40703712
    • DOI: 10.5114/bta/205474

    3 Insights on

    • Improved Cardiovascular Health
    • Reduced ACE Activity
    • Reduced HMG-CoA Reductase Inhibition

    • Low evidence

  • Probiotic Strategies for Detoxification of AFM1 in Skim Milk Using Bifidobacterium Lactis and Streptococcus Thermophiles.

    • 2025-06-30
    • Archives of Razi Institute 80(3)
    • • Atashpanjeh Masoud
      • Anvar Seyed AmirAli
      • Khajehrahimi Amir Eghbal
      • Tala Maryam
      • Sohrabi Haghdoost Nakisa

    • PubMed: 41769294
    • DOI: 10.32592/ari.2025.80.3.749

    1 Insight on

    • Reduced Aflatoxin M1 Exposure

    • Low evidence
    • Animal Study
• Undated – 10 supplement studies

  • Herbal medicine for treating psoriasis: A systematic review.

    • 2025-06
    • Systematic Review · n = 1,115
    • Complementary therapies in medicine 90
    • • Melanie Anheyer
      • Holger Cramer
      • Thomas Ostermann
      • Alfred Längler
      • Dennis Anheyer

    • PubMed: 40210174
    • DOI: 10.1016/j.ctim.2025.103173

    1 Insight on

    • Improved Psoriasis Severity

    • High evidence

  • The beneficial effects of sesame (Sesamum indicum L.) products and their bioactive compounds on cardiovascular disease risk factors in patients with diabetes: A GRADE-Assessed systematic review and meta-analysis.

    • 2025-06
    • Meta-Analysis · n = 731
    • Diabetes & metabolic syndrome 19(6)
    • • Ali Jafari
      • Helia Mardani
      • Faezeh Ghalichi
      • Fatemeh Talebian
      • Farzaneh Mokhtary
      • Fatemeh Razavi
      • Ghazaleh Eslamian

    • PubMed: 40644772
    • DOI: 10.1016/j.dsx.2025.103264

    4 Insights on

    • Reduced Triglyceride Levels
    • Reduced LDL Cholesterol
    • Reduced Fasting Blood Glucose Levels
    • Reduced Total Cholesterol

    • High evidence

  • Microenvironment-sensitive hydrogels as promising drug delivery systems for co-encapsulating microbial homeostasis probiotics and anti-inflammatory drugs to treat periodontitis.

    • 2025-06
    • Review
    • Materials today. Bio 32
    • • Yi Quan
      • Huihui Shao
      • Nuoya Wang
      • Zhonggao Gao
      • Mingji Jin

    • PubMed: 40230648
    • DOI: 10.1016/j.mtbio.2025.101711

    2 Insights on

    • Improved Oral Health
    • Improved Oral Microbial Homeostasis

    • Low evidence

  • Indole Derivatives Biosynthesis in Bifidobacterium longum subsp. infantis and the Tryptophan Substrate Availability.

    • 2025-06
    • Microbial biotechnology 18(6)
    • • Shi-Min Zhang
      • Hui-Chu Wu
      • Jia-He Hung
      • Shir-Ly Huang

    • PubMed: 40524432
    • DOI: 10.1111/1751-7915.70167

    1 Insight on

    • Increased Beneficial Indole Derivative Production

    • Low evidence

  • Impact of whey protein on lipid profiles: A systematic review and meta-analysis.

    • 2025-06
    • Meta-Analysis · n = 1,638
    • Nutrition, metabolism, and cardiovascular diseases : NMCD 35(6)
    • • Ibrahim Saeed Gataa
      • Z Abdullah
      • María Verónica González Cabrera
      • RenukaJyothi S
      • Seema Verma
      • Isha Arora
      • Mekha Monsi
      • Khursheed Muzammil
      • Rahadian Zainul

    • PubMed: 39939251
    • DOI: 10.1016/j.numecd.2025.103858

    2 Insights on

    • Reduced Triglyceride Levels
    • Increased High-Density Lipoprotein Cholesterol

    • High evidence

  • Coffee consumption and risk of multiple sclerosis: A systematic review and meta-analysis.

    • 2025-06
    • Meta-Analysis · n = 430
    • Autoimmunity reviews 24(7)
    • • Mehrad Amirnia
      • Khazar Raeisnia
      • Hamidreza Ashayeri
      • Zahra Hakimzadeh
      • Ehsan Nasiri
      • Mahnaz Talebi
      • Sarvin Sanaie
      • Amirreza Naseri

    • PubMed: 40286889
    • DOI: 10.1016/j.autrev.2025.103822

    1 Insight on

    • Reduced Risk of Multiple Sclerosis

    • High evidence

  • Effects of defatted rice bran-fortified bread on gut microbiome, cardiovascular risk, gut discomfort, wellbeing and gut physiology in healthy adults with low dietary fibre intake.

    • 2025-06
    • RCT · n = 15
    • Clinical nutrition ESPEN 67
    • • Hwei Min Ng
      • Jasjot Maggo
      • Catherine L Wall
      • Simone B Bayer
      • Jane A Mullaney
      • Diana Cabrera
      • Karl Fraser
      • Janine M Cooney
      • Catrin S Günther
      • Warren C McNabb
      • Meika Foster
      • Chris Frampton
      • Richard B Gearry
      • Nicole C Roy

    • PubMed: 40127766
    • DOI: 10.1016/j.clnesp.2025.03.045

    15 Insights on

    • Increased Fecal Lactobacilli
    • Improved Gut Microbiota Composition
    • Reduced Low-Density Lipoprotein Level
    • Increased HDL Cholesterol Levels
    • Increased Faecalibacterium prausnitzii Levels
    • Reduced Whole Gut Transit Time
    • Improved Psychological Wellbeing
    • Increased High-Density Lipoprotein Level
    • Increased Bifidobacterium longum Relative Abundance
    • Increased Bacteroides ovatus Abundance
    • Reduced Relative Abundance of Coprococcus Genus
    • Decreased Roseburia faecis Relative Abundance
    • Decreased Prevotella Copri Relative Abundance
    • Improved Gut Comfort
    • Reduced Cardiovascular Risk Profile

    • High evidence

  • Evaluating the Anti-Oxidant and Anti-Inflammatory Properties of Watercress Supplementation at Short-Term Follow-Up: A Systematic Review of Randomized Controlled Trials.

    • 2025-06
    • Review · n = 302
    • Food science & nutrition 13(6)
    • • Jimmy Wen
      • Muhammad Karabala
      • Zohaer Muttalib
      • Burhaan Syed
      • Ramy Khalil
      • Daniel Razick
      • Adam Razick
      • David Pai

    • PubMed: 40488189
    • DOI: 10.1002/fsn3.70407

    18 Insights on

    • Reduced Tumor Necrosis Factor Alpha
    • Reduced Interleukin-6 Levels
    • Increased Antioxidant Enzyme Levels
    • Reduced C-Reactive Protein Levels
    • Increased Catalase Activity
    • Increased Glutathione Peroxidase Activity
    • Reduced Malondialdehyde
    • Reduced Protein Carbonyl Level
    • Reduced Malondialdehyde Level
    • Increased Alpha-Tocopherol Level
    • Reduced Thyroid Stimulating Hormone Level
    • Increased Catalase Level
    • Reduced Nitric Oxide Level
    • Increased Retinol Level
    • Increased Beta-Carotene Level
    • Reduced Thiobarbituric Acid Reactive Substance Level
    • Reduced Interleukin-1 Level
    • Increased Thiol Level

    • High evidence

  • Efficacy and safety of Echinacea purpurea in treating upper respiratory infections and complications of otitis media in children: Systematic review and meta-analysis.

    • 2025-06
    • Meta-Analysis · n = 1,651
    • Clinical nutrition ESPEN 67
    • • Thi-Phuong-Thao Pham
      • Thi-Mai-Hoa Vu
      • Pham-Minh-Khue Doan
      • Thi-Thuy-Duong Nguyen
      • Thi-Thu-Thuy Bui
      • Thi-Hong-Linh Ha
      • Thi-Kim-Quy Hoang
      • Indra Putra Taufani
      • Hai-Anh Ha

    • PubMed: 40311928
    • DOI: 10.1016/j.clnesp.2025.04.025

    5 Insights on

    • Reduced Incidence of Upper Respiratory Tract Infections
    • Reduced Antibiotic Use
    • Reduced Upper Respiratory Tract Infection Treatment Duration
    • Reduced Otitis Media Episode Incidence
    • Reduced Otitis Media Treatment Duration

    • High evidence

  • Efficacy and Safety of Lactobacillus acidophilus LA85 in Preventing Antibiotic-Associated Diarrhea: A Randomized, Placebo-Controlled Study.

    • 2025-06
    • RCT · n = 82
    • Food science & nutrition 13(6)
    • • Jianguo Zhu
      • Yukun Sun
      • Yao Dong
      • Yunjiao Zhao
      • Zhonghui Gai
      • Shuguang Fang

    • PubMed: 40548185
    • DOI: 10.1002/fsn3.70490

    5 Insights on

    • Improved Stool Consistency
    • Reduced Antibiotic-Associated Diarrhea
    • Reduced Duration of Diarrhea
    • Improved Quality of Life
    • Reduced Incidence of Antibiotic-Associated Diarrhea

    • High evidence