October 2025 Supplement Research Papers

• October 1

  • Beetroot Supplementation as a Nutritional Strategy to Support Post-Exercise Autonomic Recovery in Postmenopausal Women: A Systematic Review and Meta-Analysis.

    • 2025-10-01
    • Review
    • Healthcare (Basel, Switzerland) 13(19)
    • • Rodrigo D Raimundo
      • Lucas Fornari Laurindo
      • Fabiana V M Gimenez
      • Jonas Benjamim
      • Luana A Gonzaga
      • Marianne P C R Barbosa
      • Marina de Morais Martins
      • Edson H Ito
      • Alexandre L Barroca
      • Giovanna de J Brito
      • Derfel R M A Folegatti
      • Andrey A Porto
      • David M Garner
      • Sandra Maria Barbalho
      • Vitor E Valenti

    • PubMed: 41095582
    • DOI: 10.3390/healthcare13192496

    2 Insights on

    • Improved Heart Rate Variability
    • Improved High-Frequency Power

    • Low evidence

  • Lab-scale production of postbiotic proteins from Bifidobacterium adolescentis with antiviral and epithelial-protective properties.

    • 2025-10-01
    • Frontiers in microbiology 16
    • • María Hernández
      • Balkys Quevedo
      • María Cabrera
      • Juan Ulloa

    • PubMed: 41103761
    • DOI: 10.3389/fmicb.2025.1646082

    2 Insights on

    • Reduced Cytotoxicity
    • Improved Intestinal Integrity

    • Low evidence

  • Exploring the Anticancer Potential of Coriolus versicolor in Breast Cancer: A Review.

    • 2025-10-01
    • Review
    • Current issues in molecular biology 47(10)
    • • Marta Ziaja-Sołtys
      • Magdalena Jaszek

    • PubMed: 41150756
    • DOI: 10.3390/cimb47100808

    1 Insight on

    • Improved Immune Function

    • Low evidence

  • The Association Between Selenium Levels and Risk of Prostate Cancer: A Systematic Review and Meta-analysis of 16,964 Participants (1980-2024).

    • 2025-10-01
    • Meta-Analysis
    • Asian Pacific journal of cancer prevention : APJCP 26(10)
    • • Mobin Ghaderi
      • Farhad Moradpour
      • Hassan Moaiery
      • Sina Fattahi
      • Hojat Dehghanbanadaki
      • Yousef Moradi

    • PubMed: 41148594
    • DOI: 10.31557/apjcp.2025.26.10.3571

    2 Insights on

    • Reduced Prostate Cancer Risk
    • Reduced Advanced Prostate Cancer Risk

    • High evidence
• October 2

  • Nutrition Strategies to Promote Sleep in Elite Athletes: A Scoping Review.

    • 2025-10-02
    • Review
    • Sports (Basel, Switzerland) 13(10)
    • • Gavin Rackard
      • Sharon M Madigan
      • James Connolly
      • Laura Keaver
      • Lisa Ryan
      • Rónán Doherty

    • PubMed: 41150477
    • DOI: 10.3390/sports13100342

    1 Insight on

    • Improved Sleep Quality

    • Low evidence
• October 3

  • Effects of quadric probiotic blends on rumen fermentation, nutrient degradability, and methane emission in sheep: an in vitro study.

    • 2025-10-03
    • AMB Express 15(1)
    • • Ali S A Saleem
      • Khaled M Al-Marakby
      • Mohamed Y Elaref
      • Sabry M Bassiony
      • Amera A Helal
      • Usama M Abdel-Monem
      • Sameh A Abdelnour

    • PubMed: 41042493
    • DOI: 10.1186/s13568-025-01955-w

    2 Insights on

    • Reduced Ammonia Concentration
    • Improved Energy Availability

    • Low evidence

  • Bifidobacterium longum P77 and Lactiplantibacillus plantarum P72 and Their Mix-Live or Heat-Treated-Mitigate Sleeplessness and Depression in Mice: Involvement of Serotonergic and GABAergic Systems.

    • 2025-10-03
    • Cells 14(19)
    • • Ji-Su Baek
      • Xiaoyang Ma
      • Hee-Seo Park
      • Dong-Yun Lee
      • Dong-Hyun Kim

    • PubMed: 41090775
    • DOI: 10.3390/cells14191547

    8 Insights on

    • Reduced Depression Symptoms
    • Increased Serotonin Levels
    • Reduced Inflammation
    • Improved Sleep Quality
    • Reduced Anxiety-like Behavior
    • Reduced Depression-like Behavior
    • Improved Sleep
    • Increased GABAergic Signaling

    • Low evidence

  • Clinical Applications of Probiotics in Pediatric Dentistry and Orthodontics-A Systematic Review.

    • 2025-10-03
    • Systematic Review
    • Nutrients 17(19)
    • • Lucia Giannini
      • Giovanna Stella
      • Giovanni Cattaneo
      • Gianna Dipalma
      • Cinzia Maspero

    • PubMed: 41097230
    • DOI: 10.3390/nu17193153

    4 Insights on

    • Reduced Duration of Traumatic Oral Lesions
    • Improved Gingival Health
    • Reduced Streptococcus Mutans Levels
    • Reduced Halitosis

    • High evidence
    • Rigorous Journal

  • Probiotic and Technological Potential of Native Lactic Acid Bacteria Strains from High Andean Forest Bee Bread: In Vitro Study.

    • 2025-10-03
    • Plant foods for human nutrition (Dordrecht, Netherlands) 80(4)
    • • Camila Bernal-Castro
      • Ángel Camargo-Herrera
      • Carolina Gutiérrez-Cortés
      • Consuelo Díaz-Moreno

    • PubMed: 41042365
    • DOI: 10.1007/s11130-025-01392-x

    5 Insights on

    • Improved Gastrointestinal Tolerance
    • Improved Gastrointestinal Survival
    • Improved Growth
    • Enhanced Growth
    • Improved Stress Tolerance

    • Low evidence
    • Animal Study
• October 5

  • Advancements in Microbial Applications for Sustainable Food Production.

    • 2025-10-05
    • Review
    • Foods (Basel, Switzerland) 14(19)
    • • Alane Beatriz Vermelho
      • Verônica da Silva Cardoso
      • Levy Tenório Sousa Domingos
      • Ingrid Teixeira Akamine
      • Bright Amenu
      • Bernard Kwaku Osei
      • Athayde Neves Junior

    • PubMed: 41097595
    • DOI: 10.3390/foods14193427

    1 Insight on

    • Improved Gastrointestinal Health

    • Low evidence
• October 6

  • Gut microbiota as a regulator of vaccine efficacy: implications for personalized vaccination.

    • 2025-10-06
    • Review
    • Gut microbes 17(1)
    • • Qi Lu
      • Yifei Feng
      • Haijian Wang
      • Kai Zhu
      • Lin Teng
      • Min Yue
      • Yan Li

    • PubMed: 41047820
    • DOI: 10.1080/19490976.2025.2563709

    1 Insight on

    • Improved Immune Function

    • Low evidence

  • Exploring Ayurveda's Potential in Parkinson's Disease: A Comprehensive Narrative.

    • 2025-10-06
    • Review · n = 126
    • Cureus 17(10)
    • • Umesh Chikkanna
      • Shivakumar Venkatram
      • Bharath Holla
      • Rohan R Mahale
      • Hemant Bhargav
      • Lakshmi Nishitha Jasti
      • Kishore Kumar Ramakrishna
      • Shivarama Varambally

    • PubMed: 41210049
    • DOI: 10.7759/cureus.93992

    3 Insights on

    • Extended ON State
    • Improved Motor Symptom
    • Reduced Side Effect

    • High evidence

  • Evaluating microbial regulation as a preventive strategy for radiation-related caries: A review.

    • 2025-10-06
    • Review
    • Head & face medicine 21(1)
    • • Hong-Xiang Ou
      • Yu Chen
      • Da-Li Zheng
      • You-Guang Lu
      • Rui-Huan Gan

    • PubMed: 41053793
    • DOI: 10.1186/s13005-025-00542-5

    2 Insights on

    • Reduced Pathogen Colonization
    • Improved Oral Microbial Balance

    • Low evidence
• October 7

  • The Role of Lactoferrin in Modulating Inflammation and Preventing Preterm Birth: A Narrative Review.

    • 2025-10-07
    • Review
    • Nutrients 17(19)
    • • Alessandro Messina
      • Safae El Motarajji
      • Bianca Masturzo
      • Paolo Manzoni

    • PubMed: 41097241
    • DOI: 10.3390/nu17193164

    8 Insights on

    • Increased Anti-Inflammatory Cytokine Levels
    • Reduced Pro-inflammatory Cytokine Levels
    • Reduced Preterm Births
    • Improved Cervical Length
    • Reduced Uterine Activity
    • Improved Oxidative Stress Marker
    • Prolonged Gestation
    • Reduced Neonatal Intensive Care Admission

    • Moderate evidence
    • Rigorous Journal

  • Whole-genome analysis of Ligilactobacillus salivarius L33, a potential probiotic strain isolated from chicken gastrointestinal tract.

    • 2025-10-07
    • Microbiology spectrum 13(10)
    • • Seyedeh Arezoo Maniee
      • Sahar Mahmoodian
      • Javad Zamani Amirzakaria
      • Amir Meimandipour
      • Vahid Shariati
      • Elahe Tavakol

    • PubMed: 40815227
    • DOI: 10.1128/spectrum.01591-24

    3 Insights on

    • Improved Growth Performance
    • Improved Resistance to Intestinal Pathogens
    • Improved Colonization Resistance

    • Low evidence
    • Animal Study

  • Placental endocrine function is controlled by maternal gut Bifidobacterium in germ-free mice.

    • 2025-10-07
    • Clinical Trial
    • Journal of translational medicine 23(1)
    • • Jorge Lopez-Tello
      • Raymond Kiu
      • Zoe Schofield
      • Matthew J Dalby
      • Douwe van Sinderen
      • Gwénaëlle Le Gall
      • Lindsay J Hall
      • Amanda N Sferruzzi-Perri

    • PubMed: 41053855
    • DOI: 10.1186/s12967-025-07198-4

    3 Insights on

    • Improved Endocrine Function
    • Reduced Fetal Resorptions
    • Reduced Fetal Loss

    • Low evidence
    • Animal Study

  • Lacticaseibacillus rhamnosus GG in a chewable colonizes the nose and facilitates local immune benefits in allergic rhinoconjunctivitis patients.

    • 2025-10-07
    • RCT
    • Microbiology spectrum 13(10)
    • • Ilke De Boeck
      • Irina Spacova
      • Eline Cauwenberghs
      • Tom Eilers
      • Thies Gehrmann
      • Karlien Van den Bossche
      • Katleen Martens
      • Sandra Condori-Catachura
      • Kato Michiels
      • Fien De Winter
      • Samir Kumar-Singh
      • Nicolas Bruffaerts
      • Ann Packeu
      • Peter W Hellings
      • Anneclaire Vroegop
      • Klara Van Gool
      • Olivier M Vanderveken
      • Sarah Lebeer

    • PubMed: 40891819
    • DOI: 10.1128/spectrum.00773-25

    3 Insights on

    • Reduced Pro-Inflammatory Cytokines
    • Reduced Severity of Allergic Rhinitis Symptoms
    • Upper Respiratory Tract Colonization

    • High evidence

  • Efficacy of botanical extracts for knee osteoarthritis: a network meta-analysis of randomized controlled trials.

    • 2025-10-07
    • Systematic Review · n = 285
    • Frontiers in pharmacology 16
    • • Chao Yan
      • Xiaotao Du
      • Yan Liu
      • Fan Xia
      • Hongling Yu
      • Yongliang Zhu
      • Tianyi Bao

    • PubMed: 41126953
    • DOI: 10.3389/fphar.2025.1619589

    2 Insights on

    • Improved Pain Score
    • Improved Function Score

    • High evidence
• October 8

  • Similar effects between animal-based and plant-based protein blend as complementary dietary protein on muscle adaptations to resistance training: findings from a randomized clinical trial.

    • 2025-10-08
    • RCT
    • Journal of the International Society of Sports Nutrition 22(1)
    • • Martin Hindermann Santini
      • Alice Erwig Leitão
      • Bruna Caruso Mazzolani
      • Fabiana Infante Smaira
      • Mariana Silva Camargo de Souza
      • Andrea Santamaria
      • Bruno Gualano
      • Hamilton Roschel

    • PubMed: 41059835
    • DOI: 10.1080/15502783.2025.2568047

    5 Insights on

    • Increased Lean Body Mass
    • Increased Appendicular Lean Mass
    • Increased Leg Lean Mass
    • Increased Muscle Cross-Sectional Area
    • Increased Lower-Body Strength

    • High evidence
• October 10

  • Selenium supplementation for management of gestational diabetes mellitus in pregnancy: a systematic review and meta-analysis of randomized controlled trials.

    • 2025-10-10
    • Meta-Analysis · n = 230
    • BMC endocrine disorders 25(1)
    • • Juan Sun
      • Lei Liu
      • Juxiang Shen
      • Juan Du

    • PubMed: 41073938
    • DOI: 10.1186/s12902-025-02045-5

    7 Insights on

    • Reduced Total Cholesterol Levels
    • Reduced Low-Density Lipoprotein Level
    • Increased HDL Cholesterol Levels
    • Improved Fasting Plasma Glucose
    • Reduced Hyperbilirubinemia Incidence
    • Unchanged Insulin Resistance
    • Unchanged Triglyceride Level

    • High evidence

  • The Potential of Fermentation-Based Processing on Protein Modification: A Review.

    • 2025-10-10
    • Review
    • Foods (Basel, Switzerland) 14(20)
    • • Negin Yousefi
      • Behdad Shokrollahi Yancheshmeh
      • Krist V Gernaey

    • PubMed: 41153997
    • DOI: 10.3390/foods14203461

    2 Insights on

    • Increased Bone Mineral Density
    • Reduced Bone Turnover

    • Low evidence

  • Maternal Dietary Anthocyanidin, Dietary Inflammatory Potential, and Risk of Small-for-Gestational-Age in China.

    • 2025-10-10
    • RCT
    • Nutrients 17(20)
    • • Binyan Zhang
      • Kun Xu
      • Baibing Mi
      • Hong Yan
      • Duolao Wang
      • Shaonong Dang
      • Ke Men

    • PubMed: 41156440
    • DOI: 10.3390/nu17203187

    1 Insight on

    • Reduced Small-for-Gestational-Age

    • High evidence
    • Rigorous Journal
• October 12

  • Characterization and immunomodulatory activity of exopolysaccharides produced by Lacticaseibacillus casei strains on macrophage cultures.

    • 2025-10-12
    • Food science and biotechnology 35(1)
    • • Windy Seftiarini
      • Rarastoeti Pratiwi
      • Abdul Rahman Siregar
      • Thu-Ha Nguyen
      • Widodo Widodo
      • Widodo Widodo

    • PubMed: 41523675
    • DOI: 10.1007/s10068-025-02010-x

    1 Insight on

    • Enhanced Innate Immune Cell Activity

    • Low evidence
• October 13

  • Probiotics: A multifaceted approach to health promotion-from disease prevention to food enrichment and delivery systems.

    • 2025-10-13
    • Review
    • AIMS microbiology 11(3)
    • • Srirengaraj Vijayaram
      • Vivekanandan K E
      • Sabariswaran Kandasamy
      • Hary Razafindralambo
      • Einar Ringø
      • Yun-Zhang Sun
      • Gayathri Kaliyannan

    • PubMed: 41078550
    • DOI: 10.3934/microbiol.2025026

    10 Insights on

    • Improved Gastrointestinal Health
    • Reduced Diarrhea Incidence
    • Improved Immune Function
    • Improved Gut Microbiota Balance
    • Improved Overall Health
    • Reduced Inflammation
    • Improved General Health
    • Modulated Gut Microbiota
    • Reduced Pathogen Activity
    • Improved Immune Modulation

    • Low evidence

  • Estrogenic Effect of Probiotics on Anxiety and Depression: A Narrative Review.

    • 2025-10-13
    • Review
    • International journal of molecular sciences 26(20)
    • • Gilberto Uriel Rosas-Sánchez
      • León Jesús Germán-Ponciano
      • Juan Francisco Rodríguez-Landa
      • Herlinda Bonilla-Jaime
      • Ofelia Limón-Morales
      • Rosa Isela García-Ríos
      • José Luis Muñoz-Carrillo
      • Oscar Gutiérrez-Coronado
      • Paola Trinidad Villalobos-Gutiérrez
      • César Soria-Fregozo

    • PubMed: 41155243
    • DOI: 10.3390/ijms26209948

    3 Insights on

    • Reduced Anxiety-like Behavior
    • Reduced Depression-like Behavior
    • Improved Mood

    • Moderate evidence
    • Rigorous Journal

  • Beyond the oral niche: Lacticaseibacillus paracasei LPC-37 unlocks oral-gastric-intestinal crosstalk for butyric acid-dependent oral inflammation alleviation.

    • 2025-10-13
    • Food & function 16(20)
    • • Yonglu Li
      • Xin Gao
      • Lihan Jiang
      • Hongdi Song
      • Chen Yang
      • Cong Wu
      • Yapeng Li
      • Shihai Yan
      • Ping Li
      • Qing Gu

    • PubMed: 41002538
    • DOI: 10.1039/d5fo02279g

    2 Insights on

    • Reduced Inflammation
    • Increased Butyrate Production

    • Low evidence
    • Rigorous Journal
    • Animal Study
• October 14

  • The Gut-Brain-Immune Axis in Environmental Sensitivity Illnesses: Microbiome-Centered Narrative Review of Fibromyalgia Syndrome, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, and Multiple Chemical Sensitivity.

    • 2025-10-14
    • Review
    • International journal of molecular sciences 26(20)
    • • Kentaro Watai
      • Masami Taniguchi
      • Kenichi Azuma

    • PubMed: 41155291
    • DOI: 10.3390/ijms26209997

    2 Insights on

    • Reduced Inflammation
    • Improved Symptoms of Environmental Sensitivity Illnesses

    • Moderate evidence
    • Rigorous Journal

  • In Vitro Probiotic Modulation of Specific Dietary Complex Sugar Consumption in Fecal Cultures in Infants.

    • 2025-10-14
    • Microorganisms 13(10)
    • • Daniela Mollova
      • Vesselin Baev
      • Ilia Iliev

    • PubMed: 41156813
    • DOI: 10.3390/microorganisms13102352

    1 Insight on

    • Improved Prebiotic Sugar Utilization

    • Low evidence

  • Anti-Aging, Anti-Inflammatory, and Cytoprotective Properties of Lactobacillus- and Kombucha-Fermented C. pepo L. Peel and Pulp Extracts with Prototype Skin Toner Development.

    • 2025-10-14
    • Molecules (Basel, Switzerland) 30(20)
    • • Aleksandra Ziemlewska
      • Zofia Nizioł-Łukaszewska
      • Martyna Zagórska-Dziok
      • Agnieszka Mokrzyńska
      • Witold Krupski
      • Magdalena Wójciak
      • Ireneusz Sowa

    • PubMed: 41157100
    • DOI: 10.3390/molecules30204082

    3 Insights on

    • Improved Antioxidant Function
    • Reduced Skin Inflammation
    • Improved Skin Aging

    • Low evidence
• October 15

  • The Role of Probiotics in Enhancing Animal Health: Mechanisms, Benefits, and Applications in Livestock and Companion Animals.

    • 2025-10-15
    • Review
    • Animals : an open access journal from MDPI 15(20)
    • • Sorin Marian Mârza
      • Camelia Munteanu
      • Ionel Papuc
      • Lăcătuş Radu
      • Robert Cristian Purdoiu

    • PubMed: 41153915
    • DOI: 10.3390/ani15202986

    4 Insights on

    • Reduced Atopic Dermatitis Severity
    • Improved Immune Modulation
    • Reduced Severity of Allergic Rhinitis Symptoms
    • No Improvement in Allergy Symptoms

    • Low evidence
• October 16

  • What Is the Involvement of Gut Microbiome in the Pathophysiology of Diabetes?

    • 2025-10-16
    • Review
    • Biomolecules 15(10)
    • • Kajetan Kiełbowski
      • Paulina Plewa
      • Jan Zadworny
      • Patrycja Stodolak
      • Anna Jędrasiak
      • Estera Bakinowska
      • Andrzej Pawlik

    • PubMed: 41154691
    • DOI: 10.3390/biom15101463

    2 Insights on

    • Improved Weight Management
    • Improved Glycemia

    • Low evidence

  • Efficacy of Serenoa repens Extract Combined With Alfuzosin Versus Alfuzosin Alone in Men With Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia: A Multicenter Randomized Study.

    • 2025-10-16
    • RCT
    • The Prostate 86(2)
    • • Giulio Bevilacqua
      • Dalila Carino
      • Stefano Salciccia
      • Alessandro Gentilucci
      • Flavio Forte
      • Massimiliano Di Marco
      • Antonio Pastore
      • Marco Martini
      • Stefano Signore
      • Alessandro Calarco
      • Martino Recchia
      • Olivia Voglino
      • Valenzi Fabio Maria
      • Pietro Viscuso
      • Fabrizio Presicce
      • Ervin Shehu
      • Marco Frisenda
      • Alessandro Sciarra

    • PubMed: 41098072
    • DOI: 10.1002/pros.70071

    3 Insights on

    • Improved Lower Urinary Tract Symptoms
    • Improved Nocturia
    • Improved Peak Urinary Flow Rate

    • High evidence
• October 17

  • Metabolic impact of dietary glycine supplementation in individuals with severe obesity.

    • 2025-10-17
    • Clinical Trial · n = 19
    • Scientific reports 15(1)
    • • Hong Chang Tan
      • Jean W Hsu
      • E Shyong Tai
      • Shaji Chacko
      • Vieon Wu
      • Paul M Yen
      • Jean-Paul Kovalik
      • Farook Jahoor

    • PubMed: 41107432
    • DOI: 10.1038/s41598-025-20511-x

    14 Insights on

    • Reduced Body Weight
    • Increased Hexanoic Acid Levels
    • Reduced Triglyceride Level
    • Increased Homocysteine Level
    • Increased Glutathione Level
    • Increased Glycine Level
    • Increased Urinary Isobutyrylglycine Level
    • Increased Tiglylglycine Level
    • Increased Isovalerylglycine Level
    • Reduced Aminotransferase Level
    • Improved Glutamate-Serine-Glycine Index
    • Increased Serine Level
    • Increased Cysteine Level
    • Increased Folate Level

    • High evidence
    • Rigorous Journal

  • Application and Challenges of Using Probiotic Lactobacillus and Bifidobacterium to Enhance Overall Health and Manage Diseases.

    • 2025-10-17
    • Review
    • Diseases (Basel, Switzerland) 13(10)
    • • Kawaljit Kaur

    • PubMed: 41149079
    • DOI: 10.3390/diseases13100345

    2 Insights on

    • Improved Immune Function
    • Improved Disease Management

    • Low evidence

  • Application of Probiotics in Cats and Dogs: Benefits and Mechanisms.

    • 2025-10-17
    • Review
    • Veterinary sciences 12(10)
    • • Jintao Sun
      • Xinshu Gu
      • Huaiyu Zhang
      • Lihong Zhao
      • Jinquan Wang
      • Xiumin Wang
      • Hui Tao
      • Zhenlong Wang
      • Bing Han

    • PubMed: 41150148
    • DOI: 10.3390/vetsci12101008

    14 Insights on

    • Improved Immune Function
    • Reduced Obesity
    • Reduced Intestinal Inflammation
    • Increased Antioxidant Activity
    • Improved Gut Health
    • Reduced Diarrhea Symptoms
    • Improved Gut Microbiota Balance
    • Improved Metabolic Health
    • Improved Immune Regulation
    • Improved Diarrhea Symptoms
    • Reduced Diarrhea
    • Improved Immune System Modulation
    • Improved Nutrient Metabolism
    • Reduced Viral Activity

    • Low evidence

  • Antidiabetic and Metabolic Effects of Turmeric (Curcuma Longa) in Patients with Type 2 Diabetes Mellitus or Hyperglycemia - A Systematic Meta-Review and Meta-Analysis.

    • 2025-10-17
    • Meta-Analysis
    • Journal of Nepal Health Research Council 23(02)
    • • Kapil Amgain
      • Richa Shah
      • Siti Munirah Md Noh
      • Shamsher Shrestha
      • Bijay Aryal
      • Lok Raj Joshi
      • Sujana Neupane
      • Shamima Abdul Rahman

    • PubMed: 41319069
    • DOI: 10.33314/jnhrc.v23i02.4708

    10 Insights on

    • Reduced Body Mass Index
    • Reduced Low-Density Lipoprotein Level
    • Reduced Blood Pressure
    • Reduced Triglyceride Levels
    • Reduced Blood Urea Nitrogen Levels
    • Increased HDL Cholesterol Levels
    • Reduced Hemoglobin A1c
    • Reduced Fasting Blood Glucose Levels
    • Reduced Total Cholesterol
    • Reduced Creatinine Level

    • High evidence
• October 18

  • Testing the Immunomodulatory Effects of Probiotic Bacillus coagulans SNZ 1969® in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.

    • 2025-10-18
    • RCT · n = 7
    • Cureus 17(10)
    • • Krishna Murthy D
      • Raunak J Soman
      • Dhruv Soman
      • Kishan Pv

    • PubMed: 41262831
    • DOI: 10.7759/cureus.94845

    3 Insights on

    • Improved Natural Killer Cell Activity
    • Increased Immunoglobulin A Levels
    • Reduced Susceptibility to Infection

    • High evidence
• October 19

  • Traditional Fermented Foods and Their Physicochemical, Sensory, Flavor, and Microbial Characteristics.

    • 2025-10-19
    • Review
    • Foods (Basel, Switzerland) 14(20)
    • • Anjun Chen

    • PubMed: 41154095
    • DOI: 10.3390/foods14203559

    4 Insights on

    • Reduced Faecal pH
    • Improved Gut Microbiota Composition
    • Increased Antioxidant Capacity
    • Improved Nutrient Absorption

    • Low evidence
• October 20

  • The performance gut: a key to optimizing performance in high-level athletes: a systematic scoping review.

    • 2025-10-20
    • Systematic Review
    • Frontiers in sports and active living 7
    • • Junior Carlone
      • Attilio Parisi
      • Alessio Fasano

    • PubMed: 41189614
    • DOI: 10.3389/fspor.2025.1641923

    2 Insights on

    • Improved Gut Microbiome Composition
    • Modulated Gut Microbiota

    • High evidence

  • A holistic guide to effective prevention and treatment for kidney stones: a systematic review exploring anti-urolithiasis approaches.

    • 2025-10-20
    • Systematic Review
    • Naunyn-Schmiedeberg's archives of pharmacology 399(3)
    • • Anood T Allam
      • Ahmed M El-Dessouki
      • Riham A El-Shiekh
      • Dina Abou-Hussein
      • Mahmoud Abdelmouti Mahmoud
      • Wagih H Marcus
      • Hassan A Ruby

    • PubMed: 41116039
    • DOI: 10.1007/s00210-025-04658-y

    4 Insights on

    • Increased Urinary Citrate Level
    • Reduced Urinary Calcium Level
    • Reduced Pain
    • Improved Stone Passage

    • High evidence

  • Folate Supplementation for Peripheral Neuropathy: A Systematic Review.

    • 2025-10-20
    • Systematic Review · n = 1,367
    • Nutrients 17(20)
    • • Ana Carolina Alves Maues
      • Mònica Gemma Moren Abat
      • María Benlloch
      • Gonzalo Mariscal

    • PubMed: 41156551
    • DOI: 10.3390/nu17203299

    8 Insights on

    • Reduced Pain
    • Reduced High-Sensitivity C-Reactive Protein Level
    • Improved Symptom Resolution
    • Improved Neuropathy Symptom Score
    • Increased Epidermal Nerve Fiber Density
    • Reduced Homocysteine Level
    • Improved Symptom Resolution Rate
    • Reduced Neuropathy Total Symptom Score

    • High evidence
    • Rigorous Journal

  • The efficacy of lactic acid bacteria-based toothpaste on oral health: a systematic review and meta-analysis.

    • 2025-10-20
    • Systematic Review
    • Frontiers in oral health 6
    • • Eun-Mi Choi
      • Su-Kyung Park

    • PubMed: 41190323
    • DOI: 10.3389/froh.2025.1668943

    5 Insights on

    • Reduced Gingival Bleeding
    • Reduced Probing Pocket Depth
    • Reduced Streptococcus Mutans Levels
    • Improved Plaque Index
    • Improved Clinical Attachment

    • High evidence
• October 21

  • The Molecular Interplay Between Oral Microbiome and Oral Cancer Pathogenesis.

    • 2025-10-21
    • Review
    • International journal of molecular sciences 26(20)
    • • Roxana-Nicoleta Urzică
      • Brigitte Crețu
      • Ana Căruntu
      • Săndica Bucurica
      • Alexandru-Titus Farcasiu
      • Laurențiu Mihai Ciupescu
      • Cristian Scheau
      • Constantin Căruntu

    • PubMed: 41155504
    • DOI: 10.3390/ijms262010212

    1 Insight on

    • Reduced Oral Malodor

    • Moderate evidence
    • Rigorous Journal

  • Does vitamin B12 influence clinical pregnancy outcome in the follicular-phase GnRH agonist protocol?

    • 2025-10-21
    • Observational
    • BMC pregnancy and childbirth 25(1)
    • • Xiaoning Wang
      • Kui Fu
      • Ying Zhang
      • Shengfang Jiang
      • Changjun Zhang

    • PubMed: 41120970
    • DOI: 10.1186/s12884-025-08250-3

    1 Insight on

    • Increased Clinical Pregnancy Rate

    • Low evidence

  • Natural Molecules, Nutraceuticals, and Engineered Nanosystems: A Comprehensive Strategy for Combating Gardnerella vaginalis-Induced Bacterial Vaginosis.

    • 2025-10-21
    • Review
    • Microorganisms 13(10)
    • • Manoj Dalabehera
      • Abdulrahman Mohammed Alhudhaibi
      • Emad M Abdallah
      • Tarek H Taha
      • Shubham Chaudhari
      • Alka Kumari
      • Rudra Narayan Subudhi
      • Charul Rathore

    • PubMed: 41156869
    • DOI: 10.3390/microorganisms13102411

    2 Insights on

    • Improved Gut Microbiota Balance
    • Reduced Symptom Severity

    • Low evidence

  • Insufficient immune protection in preterm infants due to delayed or incomplete hexavalent vaccination.

    • 2025-10-21
    • Observational · n = 82
    • Frontiers in immunology 16
    • • Elisabeth Kaiser
      • Regine Weber
      • Michelle Bous
      • Ingmar Fortmann
      • Marie-Theres Dammann
      • Janina Marißen
      • Dorothee Viemann
      • Christoph Derouet
      • Steve Hein
      • Nasenien Nourkami-Tutdibi
      • Erol Tutdibi
      • Mara Wuhrmann
      • Muriel Charlotte Hans
      • Christian Gille
      • Stephan Gehring
      • Philipp Henneke
      • Christoph Härtel
      • Sybelle Goedicke-Fritz
      • Michael Zemlin

    • PubMed: 41194926
    • DOI: 10.3389/fimmu.2025.1626057

    2 Insights on

    • Improved Immunity
    • Reduced Immune Protection

    • Moderate evidence
• October 22

  • The impact of probiotic administration on experimental in vitro and in vivo infection by Trypanosoma cruzi.

    • 2025-10-22
    • Memorias do Instituto Oswaldo Cruz 120
    • • Denise da Gama Jaén Batista
      • Lara Calheiros Missagia
      • Kelly Cristina Demarque
      • Gabriel Melo de Oliveira
      • Marcos Meuser Batista
      • Maria de Nazaré Correia Soeiro

    • PubMed: 41124405
    • DOI: 10.1590/0074-02760240272

    4 Insights on

    • Reduced Trypanosoma cruzi Parasitaemia
    • Reduced Parasite Infection in Peritoneal Mouse Macrophages
    • Improved Benznidazole Antiparasitic Activity
    • Reduced Cardiac Parasite Burden

    • Low evidence
    • Animal Study

  • Antioxidant and anti-inflammatory effects of ginger supplementation in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomised controlled trials.

    • 2025-10-22
    • Meta-Analysis
    • Inflammopharmacology 33(12)
    • • Shrin Rjabi
      • Hassan Barbarz
      • Maede Makhtoomi
      • Mohammad Reza Ahmadi
      • Hooman Zarif Najafi
      • Soroush Talakesh
      • Mehran Nouri
      • Moein Askarpour

    • PubMed: 41123858
    • DOI: 10.1007/s10787-025-01994-6

    6 Insights on

    • Reduced Tumor Necrosis Factor Alpha
    • Reduced Interleukin-6 Levels
    • Reduced C-Reactive Protein Levels
    • Improved Total Antioxidant Capacity
    • Reduced Malondialdehyde Level
    • Improved Superoxide Dismutase Level

    • High evidence

  • Riboflavin supplements for blood pressure lowering in adults.

    • 2025-10-22
    • Meta-Analysis · n = 320
    • The Cochrane database of systematic reviews 2025(10)
    • • Kathryn E Bradbury
      • Sean Coffey
      • Nikki Earle
      • Cliona Ni Mhurchu
      • Andrew B Jull

    • PubMed: 41123035
    • DOI: 10.1002/14651858.cd015464.pub2

    3 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Systolic Blood Pressure
    • Increased Adverse Event

    • High evidence

  • Nutrition and Gut Microbiome in the Prevention of Food Allergy.

    • 2025-10-22
    • Systematic Review · n = 5,685
    • Nutrients 17(21)
    • • Mohammad Aminullah Nurain Binti
      • János Tamás Varga

    • PubMed: 41228392
    • DOI: 10.3390/nu17213320

    2 Insights on

    • Reduced Food Allergy Incidence
    • No Significant Reduction in Food Allergy

    • High evidence
    • Rigorous Journal
• October 23

  • Vitamin C supplementation in patients with hypothyroidism requiring high-dose levothyroxine: a proof-of-concept pilot study.

    • 2025-10-23
    • RCT · n = 6
    • Frontiers in endocrinology 16
    • • Adnan Agha
      • Bachar Afandi
      • Javed Yasin
      • Charu Sharma
      • Mohammad Hamdan Alshaer
      • Mouza Ali Saif Alshamsi
      • Dana Ebraheim Yaaqeib
      • Bayena Khamis Eshaq Alblooshi
      • Juma AlKaabi

    • PubMed: 41210509
    • DOI: 10.3389/fendo.2025.1679835

    2 Insights on

    • Increased Serum Free Thyroxine Levels
    • Reduced Hypothyroid Symptom Score

    • High evidence

  • The crosstalk between probiotics and T cell immunity.

    • 2025-10-23
    • Review
    • Frontiers in immunology 16
    • • Yuanyuan Liu
      • Xu Cao
      • Hongwei Liu
      • Wencan Zhang

    • PubMed: 41208998
    • DOI: 10.3389/fimmu.2025.1695840

    4 Insights on

    • Improved Immune Function
    • Improved Atopic Dermatitis Symptoms
    • Improved Cell-mediated Immunity
    • Improved Allergic Immune Responses

    • Low evidence

  • The Effect of N-Acetylcysteine (NAC) on Neurometabolites and Cognitive Function in Adults With Alcohol Use Disorder: A Preliminary Randomized Controlled Trial.

    • 2025-10-23
    • RCT · n = 23
    • Neuropsychopharmacology reports 45(4)
    • • Kristiane Yacou Dunbar
      • Gezelle Dali
      • Marilena M DeMayo
      • Warren Logge
      • Tristan Hurzeler
      • Catherine Kelly
      • Joshua Watt
      • Lindsay M Squeglia
      • Anna E Kirkland
      • Paul S Haber
      • Kirsten C Morley

    • PubMed: 41128676
    • DOI: 10.1002/npr2.70066

    5 Insights on

    • Reduced Uric Acid Levels
    • Reduced Glutamate Level
    • Reduced N-acetylaspartate Level
    • Improved Distractor Interference
    • Improved Set Shifting Ability

    • High evidence

  • A systematic review of the mechanisms of cardiovascular disease reduction by dietary flavonoids: the impact of anthocyanins on flow-mediated dilation and blood rheology.

    • 2025-10-23
    • Systematic Review
    • BMC nutrition 11(1)
    • • Shiva Khani
      • Jeremy Spencer

    • PubMed: 41131574
    • DOI: 10.1186/s40795-025-01086-2

    1 Insight on

    • Improved Flow-Mediated Dilation

    • High evidence

  • Preserving edible biodiversity through indigenous dairy emulsions: valorization of traditional milk systems for a resilient future.

    • 2025-10-23
    • Review
    • Frontiers in nutrition 12
    • • Anand Kumar
      • Muskan Yadav
      • Sadaqat Ali
      • Itu Dutta
      • Selva Kumar T
      • Vidhu Yadav
      • Tharindu Trishan Dapana Durage
      • Fahad Saad Alhodieb
      • Saleh A Alsanie

    • PubMed: 41211215
    • DOI: 10.3389/fnut.2025.1693995

    1 Insight on

    • Improved Gastrointestinal Health

    • Low evidence

  • Intravaginal Vitamin C for the Treatment and Prevention of Bacterial Vaginosis: A Systematic Review and Meta-analysis.

    • 2025-10-23
    • Meta-Analysis · n = 1
    • Obstetrics and gynecology 147(4)
    • • Yannay Khaikin
      • Praniya Elangainesan
      • Eliot Winkler
      • Kuan Liu
      • Amanda Selk
      • Mark H Yudin

    • PubMed: 41129824
    • DOI: 10.1097/aog.0000000000006092

    2 Insights on

    • Improved Cure Rate
    • Reduced Recurrence Rate

    • High evidence

  • Microbial allies in skin trauma recovery: from immune modulation to engineered probiotic therapeutics.

    • 2025-10-23
    • Review
    • Burns & trauma 14
    • • Aline Yen Ling Wang
      • Ana Elena Aviña
      • Yen-Yu Liu
      • Huang-Kai Kao

    • PubMed: 41550964
    • DOI: 10.1093/burnst/tkaf068

    2 Insights on

    • Improved Wound Healing
    • Improved Diabetic Foot Ulcer Healing

    • Low evidence
• October 24

  • Effectiveness of Selenium Supplementation in the Treatment of Graves-Basedow Disease: A Scoping Review.

    • 2025-10-24
    • Systematic Review · n = 15
    • Medical sciences (Basel, Switzerland) 13(4)
    • • Hernando Vargas-Uricoechea
      • Alejandro Castellanos-Pinedo
      • Karen Urrego-Noguera
      • María V Pinzón-Fernández
      • Ivonne A Meza-Cabrera
      • Hernando Vargas-Sierra

    • PubMed: 41283242
    • DOI: 10.3390/medsci13040241

    4 Insights on

    • Increased Serum Free Thyroxine Levels
    • Reduced Thyroid Peroxidase Antibody Level
    • Reduced Thyroglobulin Antibody Level
    • Reduced TSH Receptor Antibody Level

    • High evidence
• October 25

  • Functional and Compositional Changes in Ileal Microbiota in Piglets During the Nursing Period Revealed by 16s rRNA Gene and Metagenomics.

    • 2025-10-25
    • Animals : an open access journal from MDPI 15(21)
    • • Boxuan Yang
      • Pengfei Shen
      • Zhijian Xu
      • Jianbo Yang
      • Bo Song
      • Hui Jiang
      • Jianmin Chai
      • Jiangchao Zhao
      • Feilong Deng
      • Ying Li

    • PubMed: 41227433
    • DOI: 10.3390/ani15213102

    1 Insight on

    • No Direct Health Outcome Reported

    • Low evidence
• October 26

  • Exploring the Anticancer Potential of the Multistrain Probiotic Formulation OxxySlab in Bladder Cancer Cell Lines.

    • 2025-10-26
    • Antioxidants (Basel, Switzerland) 14(11)
    • • Valeria Ciummo
      • Alessia Ciafarone
      • Serena Altamura
      • Francesca Lombardi
      • Marcella Reale
      • Maria Grazia Cifone
      • Benedetta Cinque
      • Paola Palumbo

    • PubMed: 41300439
    • DOI: 10.3390/antiox14111282

    4 Insights on

    • Inhibited Epithelial-Mesenchymal Transition
    • Reduced Epithelial-Mesenchymal Transition
    • Increased Oxidative Stress
    • Selective Sparing of Normal Urothelial Cells

    • Low evidence
• October 27

  • The effect of Withania somnifera (Ashwagandha) on mental health symptoms in individuals with mental disorders: systematic review and meta-analysis.

    • 2025-10-27
    • Review
    • BJPsych open 11(6)
    • • Mattia Marchi
      • Pietro Grenzi
      • Antonio Travascio
      • Daniele Uberti
      • Edoardo De Micheli
      • Fabio Quartaroli
      • Giuseppe Laquatra
      • Luca Pingani
      • Silvia Ferrari
      • Gian M Galeazzi

    • PubMed: 41140145
    • DOI: 10.1192/bjo.2025.10885

    4 Insights on

    • Reduced Depression Symptoms
    • Reduced Anxiety
    • Improved Sleep Quality
    • Reduced Stress

    • Low evidence
• October 28

  • Lactobacillus Salivarius-Derived Indole-3-Acetic Acid Promotes AHR-PARP1 Axis-Mediated DNA Repair to Mitigate Intestinal Aging.

    • 2025-10-28
    • Advanced science (Weinheim, Baden-Wurttemberg, Germany) 13(4)
    • • Zheng Cao
      • Cui Zhang
      • Hehua Lei
      • Weichuan Lin
      • Wenkai Yu
      • Xin Gao
      • Yanmeng He
      • Xinzhi Li
      • Qingwei Xiang
      • Zhiwen Zhang
      • Weifei Luo
      • Andrew D Patterson
      • Limin Zhang
      • Gang Chen

    • PubMed: 41147383
    • DOI: 10.1002/advs.202515794

    5 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Inflammation
    • Reduced Intestinal Aging
    • Reduced Cellular Senescence
    • Enhanced DNA Repair

    • Low evidence

  • The Effect of Yacon Consumption on Glycemic Control and Lipid Profiles: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

    • 2025-10-28
    • Meta-Analysis · n = 239
    • Endocrinology, diabetes & metabolism 8(6)
    • • Maryam Nilghaz
      • Fatemeh Sheikhhossein
      • Mahnoush Mehrzad Samarin
      • Mohammad Reza Amini
      • Mahsa Elahikhah
      • Moharam Jalalzadeh
      • Maryam Khakbaz
      • Negin Lohrasbi
      • Sajjad Etesamnia
      • Fatemeh Torkizadeh
      • Azita Hekmatdoost

    • PubMed: 41152200
    • DOI: 10.1002/edm2.70121

    7 Insights on

    • Reduced Low-Density Lipoprotein Level
    • Reduced Triglyceride Levels
    • Improved Insulin Levels
    • Increased HDL Cholesterol Levels
    • Reduced Total Cholesterol
    • Reduced Fasting Blood Glucose
    • Reduced HOMA-IR

    • High evidence

  • An oral M-cell targeted Lactococcus lactis vaccine against Echinococcus multilocularis infection.

    • 2025-10-28
    • Frontiers in immunology 16
    • • Yang Xiao
      • Zhao-Hui Luo
      • Shun-Juan Wang
      • Yao Dai
      • Jia-Yu Chen
      • Jia-Yong Cui
      • Run-Le Li
      • Feng Tang

    • PubMed: 41229421
    • DOI: 10.3389/fimmu.2025.1683003

    4 Insights on

    • Enhanced Immune Response
    • Increased Lymphocyte Proliferation
    • Increased Regulatory T Cell Response
    • Reduced Echinococcus multilocularis Infection Burden

    • Low evidence
    • Animal Study

  • Probiotic Combination of Bifidobacterium adolescentis and Bifidobacterium bifidum Enhances Lipophagy in MAFLD Rats.

    • 2025-10-28
    • MicrobiologyOpen 14(6)
    • • Mahtab Mehboodi
      • Mohammad Mehdi Alinaghi
      • Maryam Behmanesh
      • Mohammad Hosein Kolahkaj
      • Milad Pour Mohammad Ali Namdari
      • Hadis Khanbabaie
      • Arezoo Harsjian
      • Narges Namavar
      • Saman Rabiei
      • Maryam Sadat Pishva
      • Payam Baziyar
      • Sara Rashki Ghaleno
      • Mohammad Hasan Maleki

    • PubMed: 41157845
    • DOI: 10.1002/mbo3.70100

    6 Insights on

    • Improved Lipid Metabolism
    • Prevention of Weight Gain
    • Enhanced Autophagy
    • Reduced Hepatic Lipid Accumulation
    • Improved Blood Lipid Profile
    • Preserved Liver Structure

    • Low evidence
    • Animal Study
• October 29

  • Microbial Transformation of Dietary Glycerol Contributes to Intestinal Acrolein Formation and Urinary Excretion.

    • 2025-10-29
    • Observational · n = 20
    • Molecular nutrition & food research 69(24)
    • • Clarissa Schwab
      • Hanna Lang
      • Simone Stegmüller
      • Jiri Hosek
      • Angeliki Marietou
      • Lucia Huertas-Díaz
      • Qing Li
      • Asta Petrine Smedgaard Krings
      • Andrea Zander
      • Ulrik Kræmer Sundekilde
      • Elke Richling

    • PubMed: 41159664
    • DOI: 10.1002/mnfr.70289

    2 Insights on

    • Increased Endogenous Acrolein Formation
    • Increased Urinary Acrolein Biomarkers

    • Moderate evidence
    • Rigorous Journal

  • Effects of Acute Fish Oil Supplementation on Muscle Function and Soreness After Eccentric Contraction-Induced Muscle Damage.

    • 2025-10-29
    • RCT
    • Nutrients 17(21)
    • • Sang-Rok Lee
      • Dean Directo
      • Yangmi Kang
      • Joshua Stein
      • Mason Calvert
      • Yong Woo An
      • Do-Houn Kim

    • PubMed: 41228481
    • DOI: 10.3390/nu17213408

    4 Insights on

    • Reduced Tumor Necrosis Factor Alpha
    • Reduced Muscle Soreness
    • Improved Vertical Jump Performance
    • Improved Isometric Maximal Voluntary Contraction Torque

    • High evidence
    • Rigorous Journal

  • Probiotics Decrease C-Reactive Protein Levels in Depression Depending on Metabolic Syndrome Presence or Antidepressant Treatment - Secondary Results of a Randomized Clinical Trial.

    • 2025-10-29
    • RCT · n = 88
    • Current neuropharmacology 23
    • • Oliwia Gawlik Kotelnicka
      • Adam Wysokinski
      • Agata Gajewska
      • Karolina Czarnecka-Chrebelska
      • Karolina Kopacz
      • Anna Skowrońska
      • Ewa Pikus
      • Ewa Brzeziańska-Lasota
      • Dominik Strzelecki

    • PubMed: 41177800
    • DOI: 10.2174/011570159x371175251002220658

    3 Insights on

    • Reduced C-Reactive Protein Levels
    • No Change in Inflammation Markers
    • No Significant Change in Tumor Necrosis Factor Alpha Levels

    • High evidence

  • Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review).

    • 2025-10-29
    • Review
    • Molecular medicine reports 33(1)
    • • Yanhua Han
      • Yuchao Jia
      • Lili Chen
      • Mingyao Zhang

    • PubMed: 41170726
    • DOI: 10.3892/mmr.2025.13731

    1 Insight on

    • Reduced Respiratory Tract Infections

    • Low evidence

  • Lychee Fermented by Mixed Probiotic Strains Alleviates D-Galactose-Induced Skeletal Muscle and Intestinal Aging in Mice.

    • 2025-10-29
    • Foods (Basel, Switzerland) 14(21)
    • • Huixian Han
      • Jin Tao
      • Xiaoyue Bai
      • Yizhi Jing
      • Zhengyuan Zhai
      • Junjie Luo
      • Wanxiang Zhang
      • Dan Gan
      • Yanling Hao

    • PubMed: 41227656
    • DOI: 10.3390/foods14213684

    7 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Colonic Inflammation
    • Reduced Intestinal Inflammation
    • Improved Gut Microbiota Balance
    • Reduced Oxidative Stress
    • Improved Intestinal Motility
    • Improved Skeletal Muscle Function

    • Low evidence

  • Harnessing Probiotics to Combat Candidiasis: Mechanisms, Evidence, and Future Directions.

    • 2025-10-29
    • Review
    • Journal of fungi (Basel, Switzerland) 11(11)
    • • Emma Wright
      • Nisha Valand
      • Umakhanth Venkatraman Girija

    • PubMed: 41295160
    • DOI: 10.3390/jof11110779

    4 Insights on

    • Reduced Candida albicans Colonization
    • Reduced Vaginal Candidiasis Symptoms
    • Improved Clinical Outcomes in Candidiasis
    • Reduced Oral Candida Colonization

    • Low evidence
• October 30

  • Microbiome-targeted nanoplatforms and engineering approaches in breast cancer therapy.

    • 2025-10-30
    • Review
    • Molecular cancer 24(1)
    • • Zufa Sabeel
      • Zhao Yang

    • PubMed: 41168838
    • DOI: 10.1186/s12943-025-02456-x

    1 Insight on

    • Increased Abundance of Bifidobacterium

    • Low evidence

  • Effects of nicotinamide supplementation in normal-tension glaucoma: a crossover placebo-controlled randomised clinical trial.

    • 2025-10-30
    • RCT
    • The British journal of ophthalmology 110(4)
    • • Ahnul Ha
      • Young Kook Kim
      • Chang Kyu Lee
      • Pete A Williams
      • James E Morgan
      • Young In Shin
      • Eunsol Kim
      • Myungjin Kim
      • Seungsoo Rho

    • PubMed: 41167798
    • DOI: 10.1136/bjo-2025-328096

    2 Insights on

    • Improved Photopic Negative Response Amplitude
    • Improved B-wave Amplitude

    • High evidence

  • In Vitro Detoxification of Fumonisin B1 (FB1) into Hydrolyzed Fumonisin B1 (HFB1) by Lactobacillus spp. Isolated from Pig Caecum.

    • 2025-10-30
    • International journal of molecular sciences 26(21)
    • • Huu Anh Dang
      • Attila Zsolnai
      • Mariam Kachlek
      • Veronika Halas
      • Diana Giannuzzi
      • Stefano Schiavon
      • Isaac Hyeladi Malgwi

    • PubMed: 41226597
    • DOI: 10.3390/ijms262110557

    2 Insights on

    • Reduced Fumonisin B1 Levels
    • Increased Hydrolyzed Fumonisin B1 Conversion

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Latilactobacillus sakei CNTA 173 Reduces Fat Mass by Modulating Sphingolipid Metabolism in Diet-Induced Obese Wistar Rats.

    • 2025-10-30
    • Journal of agricultural and food chemistry 73(45)
    • • Ignacio Goyache
      • Lorena Valdes-Varela
      • Raquel Virto
      • Iñigo Clemente-Larramendi
      • Miguel López-Yoldi
      • Ana Romo-Hualde
      • Ana Gloria Gil
      • Fermín I Milagro
      • Paula Aranaz

    • PubMed: 41166528
    • DOI: 10.1021/acs.jafc.5c10238

    5 Insights on

    • Improved Glucose Tolerance
    • Improved Inflammatory Biomarkers
    • No Observed Toxicity
    • Reduced Adiposity
    • Reduced Ceramide Production

    • Low evidence
    • Rigorous Journal
• October 31

  • Dietary interventions in skin ageing: a systematic review and meta-analysis.

    • 2025-10-31
    • Meta-Analysis
    • Journal of physiological anthropology 44(1)
    • • Jun Yan Ng
      • Xuan Min Gail Yan Ng
      • Qi Yi Ambrose Wong
      • Fook Tim Chew

    • PubMed: 41174715
    • DOI: 10.1186/s40101-025-00408-4

    7 Insights on

    • Improved Skin Hydration
    • Improved Skin Barrier Function
    • Reduced Wrinkle Depth
    • Improved Skin Aging
    • Reduced Wrinkle Severity
    • Reduced Skin Redness
    • Reduced Pigment Spots

    • High evidence

  • Berries derived Polyphenols and Bone Health: A Systematic Review.

    • 2025-10-31
    • Systematic Review
    • Nutrients 17(21)
    • • Simone Perna
      • Giorgia F Ruina
      • Asmita Acharya
      • Giuseppe Mazzola
      • Mariangela Rondanelli
      • Patrizia Riso

    • PubMed: 41228518
    • DOI: 10.3390/nu17213440

    3 Insights on

    • Increased Total Hip Bone Mineral Density
    • Improved Bone Turnover Marker
    • Improved Calcium Retention

    • High evidence
    • Rigorous Journal

  • Low-Cost Protocol for Quantitative Measurement of Streptococcus salivarius in Human Saliva.

    • 2025-10-31
    • Observational
    • Life (Basel, Switzerland) 15(11)
    • • Flavia-Cristina Al-Akel
      • Lacramioara Eliza Chiperi
      • Krisztina Eszter Vas
      • Edit Szekely
      • Claudia Raluca Mariean
      • Corina Eugenia Budin
      • Anca Bacarea

    • PubMed: 41302119
    • DOI: 10.3390/life15111695

    1 Insight on

    • Reduced Streptococcus salivarius Colonization

    • Low evidence

  • Efficacy of vitamin C in COVID-19 management: a systematic review and meta-analysis.

    • 2025-10-31
    • Meta-Analysis · n = 19
    • BMC infectious diseases 25(1)
    • • Shuyi Zhou
      • Shijie Gao
      • Yujie Fang
      • Na Zhang
      • Guansheng Ma

    • PubMed: 41174501
    • DOI: 10.1186/s12879-025-11891-6

    2 Insights on

    • Reduced Short-term Mortality
    • Reduced In-hospital Mortality

    • High evidence

  • Ylang-ylang and lavender aromatherapy for paediatric dental anxiety: A randomized control trial in first restorative appointment.

    • 2025-10-31
    • RCT
    • Bioinformation 21(10)
    • • Amol N Patil
      • Sneha N Kamble
      • Pranali Shelke
      • Priya Telang
      • Aishwarya Shelar
      • Mrunalini Kadam

    • PubMed: 41623781
    • DOI: 10.6026/973206300213686

    1 Insight on

    • Reduced Anxiety

    • High evidence

  • Dietary probiotic supplementation with Lactococcus lactis and Bacillus velezensis enhances growth performance, meat quality, blood profiles, and cecal and feed microbiota in growing rabbits.

    • 2025-10-31
    • Animal biotechnology 36(1)
    • • Nada Elbaz
      • Elwy A Ashour
      • Samar S Bassiony
      • Ahmed I Elsherbeni
      • Samir A Mahgoub
      • Ali O Osman
      • Islam Sabike
      • Naif A Al-Gabri
      • Mahmoud Moustafa
      • Mohammed Al-Shehri
      • Mohamed E Abd El-Hack

    • PubMed: 41173468
    • DOI: 10.1080/10495398.2025.2577947

    3 Insights on

    • Improved Gut Microbiota
    • Improved Gut Microbiota Composition
    • Improved Growth Performance

    • Low evidence
    • Animal Study

  • Lactobacillus crispatus KBL693 alleviates atopic dermatitis symptoms through immune modulation.

    • 2025-10-31
    • Journal of microbiology (Seoul, Korea) 63(10)
    • • Seokcheon Song
      • Jun-Hyeong Kim
      • Sung Jae Jang
      • Eun Jung Jo
      • Sang Kyun Lim
      • GwangPyo Ko

    • PubMed: 41164963
    • DOI: 10.71150/jm.2509005

    3 Insights on

    • Improved Atopic Dermatitis Symptoms
    • Reduced Type 2 Immune Responses
    • Increased Regulatory T Cell Expansion

    • Low evidence

  • A Retrospective Study of the Association between Low Vitamin B1 in the Blood and Cognitive Impairment in Patients with Alzheimer's Disease.

    • 2025-10-31
    • Observational
    • Journal of nutritional science and vitaminology 71(5)
    • • Yuji Higaki
      • Yu Kobayashi

    • PubMed: 41183968
    • DOI: 10.3177/jnsv.71.421

    1 Insight on

    • Reduced Cognitive Function

    • Low evidence

  • The effect of long-term magnesium intake on inflammatory markers in patients with metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.

    • 2025-10-31
    • Systematic Review · n = 444
    • Frontiers in nutrition 12
    • • Weinai Wang
      • Jiayong Wang
      • Yufeng Yang
      • Yan Shi

    • PubMed: 41245414
    • DOI: 10.3389/fnut.2025.1692937

    1 Insight on

    • Reduced C-Reactive Protein Levels

    • High evidence
• Undated – 13 supplement studies

  • Caffeine and taurine: a systematic review and network meta-analysis of their individual and combined effects on physical capacity, cognitive function, and physiological markers.

    • 2025-10
    • Systematic Review
    • Journal of the International Society of Sports Nutrition 22(1)
    • • Hengzhi Deng
      • Li Wang
      • Ping Liu
      • Mohamed Nashrudin Bin Naharudin
      • Xiaohan Fan

    • PubMed: 41032459
    • DOI: 10.1080/15502783.2025.2566371

    5 Insights on

    • Reduced Lactate Levels
    • Improved Reaction Time
    • Improved Athletic Performance
    • Improved Anaerobic Capacity
    • Changed Heart Rate

    • High evidence

  • Therapeutic effects of chromium supplementation on women with polycystic ovarian syndrome: A systematic review and meta-analysis.

    • 2025-10
    • Meta-Analysis · n = 683
    • Endocrinologia, diabetes y nutricion 72(8)
    • • Mohammed Hamsho
      • Yazan Ranneh
      • Abdulmannan Fadel

    • PubMed: 41067797
    • DOI: 10.1016/j.endien.2025.501578

    13 Insights on

    • Improved Insulin Sensitivity
    • Reduced Low-Density Lipoprotein Level
    • Reduced Triglyceride Levels
    • Reduced Total Cholesterol
    • Increased Total Serum Antioxidant Capacity
    • Reduced Insulin Level
    • Reduced High-Sensitivity C-Reactive Protein Level
    • Reduced Malondialdehyde
    • Reduced Follicle Stimulating Hormone
    • Reduced Prolactin
    • Increased Ovulation Incidence
    • Reduced HOMA-IR
    • Reduced Luteinizing Hormone Level

    • High evidence

  • Effect of selenium supplementation on inflammatory markers and joint symptoms in patients with rheumatoid arthritis: A meta-analysis and systematic review.

    • 2025-10
    • Meta-Analysis · n = 367
    • Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 91
    • • Manyu Long
      • Shaohong Xu
      • Songyuan Tie
      • Shuming Dong
      • Hui Liang
      • Jing Wang
      • Shuya Wang

    • PubMed: 40695138
    • DOI: 10.1016/j.jtemb.2025.127695

    2 Insights on

    • Reduced Pain
    • Reduced Joint Tenderness

    • High evidence

  • Effects of antioxidants on oxidative stress in adult patients with coronary artery disease: A systematic review.

    • 2025-10
    • Systematic Review
    • Clinical nutrition ESPEN 69
    • • Islam M Alhusban
      • Misook L Chung
      • Martha Biddle

    • PubMed: 40914496
    • DOI: 10.1016/j.clnesp.2025.08.037

    1 Insight on

    • Reduced Oxidative Stress

    • High evidence

  • The role of whey protein supplementation after one-anastomosis gastric bypass: Results of a double-blind randomized controlled trial.

    • 2025-10
    • RCT
    • Clinical nutrition ESPEN 69
    • • Keivan Sabooni
      • Farnaz Farsi
      • Shiva Safari
      • Mohammad Mahjoubi
      • Amir Hossein Davarpanah Jazi
      • Delaram Moosavi
      • Zahra Gholi
      • Mohammad Kermansaravi
      • Shahab Shahabi

    • PubMed: 40744414
    • DOI: 10.1016/j.clnesp.2025.07.1122

    2 Insights on

    • Reduced Lean Body Mass Loss
    • Preserved Muscle Mass

    • High evidence

  • Artichoke and cardiometabolic health: A systematic and meta-analytic synthesis of current evidence.

    • 2025-10
    • Meta-Analysis
    • Diabetes & metabolic syndrome 19(10)
    • • Ali Jafari
      • Mohammad Amin Karimi
      • Mahsa Mahmoudinezhad
      • Fatemeh Razavi
      • Helia Mardani
      • Vali Musazadeh

    • PubMed: 41270328
    • DOI: 10.1016/j.dsx.2025.103328

    11 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Waist Circumference
    • Reduced Body Mass Index
    • Reduced Low-Density Lipoprotein Level
    • Reduced Systolic Blood Pressure
    • Reduced Triglyceride Levels
    • Improved Insulin Levels
    • Reduced Total Cholesterol
    • Reduced Alanine Aminotransferase Level
    • Reduced Alkaline Phosphatase Level
    • Reduced HOMA-IR

    • High evidence

  • Bilateral keratomalacia years after biliopancreatic diversion with duodenal switch surgery: A case of severe vitamin A deficiency and literature review.

    • 2025-10
    • Review
    • The Journal of international medical research 53(10)
    • • Jaron C Sanchez
      • Omar Nusair
      • Dipen Kumar
      • Mohammad Soleimani

    • PubMed: 41130926
    • DOI: 10.1177/03000605251387932

    2 Insights on

    • Improved Vision
    • Resolved Keratomalacia

    • Low evidence

  • Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 administration to Long-Evans rats has interactive effects with sex and diet on anxiety-related feeding behaviors and specific endocrine outcomes.

    • 2025-10
    • Physiology & behavior 300
    • • Elizabeth M Myles
      • M Elizabeth O'Leary
      • Isaac D Romkey
      • Sara I Hamm
      • Laura Dauphinee
      • Amanda Piano
      • Stéphane Bronner
      • Tara S Perrot

    • PubMed: 40664306
    • DOI: 10.1016/j.physbeh.2025.115030

    2 Insights on

    • Reduced Anxiety-Related Feeding Behavior
    • Increased Feeding Bouts in the Center of the Open Field

    • Low evidence
    • Animal Study

  • The effects of purslane consumption on blood pressure in adults: A grading of recommendations, assessment, development, and evaluation-assessed systematic review and meta-analysis of randomized controlled trials.

    • 2025-10
    • Review
    • Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 30(1)
    • • Mahdi Vajdi
      • Negin Tahvilian
      • Shirin Hassanizadeh
      • Malihe Jafari
      • Gholamreza Askari

    • PubMed: 41306619
    • DOI: 10.4103/jrms.jrms_48_24

    2 Insights on

    • Reduced Diastolic Blood Pressure
    • Reduced Systolic Blood Pressure

    • Low evidence

  • Microbiota basis of antidepressant effects of Zhi-zi-chi Decoction: Lactobacillus rhamnosus and gut microbiota metabolism.

    • 2025-10
    • Chinese herbal medicines 17(4)
    • • Jing He
      • Zixin Zhao
      • Ying Ye
      • Yujia Zhai
      • Dexun Yu
      • Fangyuan Gao
      • Jianlin Wu
      • Jun Wen
      • Tingting Zhou

    • PubMed: 41399797
    • DOI: 10.1016/j.chmed.2025.05.001

    3 Insights on

    • Enhanced Antioxidant Response
    • Improved Depressive Symptoms
    • Reduced Depression-like Behavior

    • Low evidence

  • Comparative effectiveness of oral nutritional supplements in preventing respiratory tract infections among adults: a systematic review and network meta-analysis.

    • 2025-10
    • Meta-Analysis · n = 751
    • EClinicalMedicine 88
    • • Zhixin Zhu
      • Xiaoxia Zhu
      • Yanru Chu
      • Bing Zhang
      • Yi Chen

    • PubMed: 40969681
    • DOI: 10.1016/j.eclinm.2025.103479

    1 Insight on

    • Reduced Respiratory Tract Infections

    • High evidence

  • Role of Echinacea in the management and prevention of acute respiratory tract infections in children: A systematic review of the evidence.

    • 2025-10
    • Review
    • Journal of family & community medicine 32(4)
    • • Ahlam Mazi
      • Reem M Alqahtani

    • PubMed: 41234257
    • DOI: 10.4103/jfcm.jfcm_144_25

    6 Insights on

    • Reduced Viral Load
    • Reduced Fever Duration
    • Reduced Symptom Severity
    • Reduced Infection Incidence
    • Reduced Antibiotic Use
    • Reduced Symptom Duration

    • Low evidence

  • The potential bactericidal effect of oral probiotics on extrinsic black stain-associated bacteria in children: An in-vitro and in-vivo study.

    • 2025-10
    • Journal of dental sciences 20(4)
    • • Nour Wahba
      • Dina Sharaf
      • Mohamed Wagdy
      • Ahmed El-Motayam
      • Basma Nagi

    • PubMed: 41040574
    • DOI: 10.1016/j.jds.2025.04.032

    1 Insight on

    • Reduced Bacterial Load

    • Low evidence