February 2026 Supplement Research Papers

• February 1

  • The Combined Use of Hydroxymethylbutyrate and Branched-Chain Amino Acids to Counteract Uremic Sarcopenia.

    • 2026-02-01
    • RCT
    • Nutrients 18(3)
    • • Giulia Marrone
      • Manuela Di Lauro
      • Kevin Cornali
      • Sabri Shamsan Hassan
      • Gabriele D'Urso
      • Luca Di Marco
      • Sara Dominijanni
      • Roberto Palumbo
      • Anna Paola Mitterhofer
      • Annalisa Noce

    • PubMed: 41683304
    • DOI: 10.3390/nu18030483

    3 Insights on

    • Reduced Inflammatory Markers
    • Increased Muscle Mass
    • Reduced Oxidative Stress

    • High evidence
    • Rigorous Journal
• February 2

  • Design and immunogenicity of a recombinant Saccharomyces boulardii secreting the P2-VP8 subunit rotavirus vaccine.

    • 2026-02-02
    • Clinical Trial
    • Scientific reports 16(1)
    • • Ibrahim Farhani
      • Ahad Yamchi
      • Hadi Razavi Nikoo
      • Fatemeh T Shamsabadi
      • Shahriyar Abdoli
      • R Holland Cheng
      • Majid Shahbazi

    • PubMed: 41629582
    • DOI: 10.1038/s41598-026-37374-5

    2 Insights on

    • Immune Response to Rotavirus Vaccine Antigen
    • Reduced Immunogenicity After Oral Vaccination

    • High evidence
    • Rigorous Journal

  • Immunomodulatory effects and gut microbiota modulation by brewer's yeast mannatide in cyclophosphamide-induced immunosuppression mice.

    • 2026-02-02
    • Archives of microbiology 208(4)
    • • Shuang Zhao
      • Haidi Wang
      • Shuo Zhao
      • Jia Yu
      • Yuxi Wei

    • PubMed: 41627476
    • DOI: 10.1007/s00203-026-04725-9

    3 Insights on

    • Improved Gut Microbiota Composition
    • Improved Immune Function
    • Improved Gut Integrity

    • Low evidence
    • Animal Study

  • Gut Microbiota and Exercise-Induced Fatigue: A Narrative Review of Mechanisms, Nutritional Interventions, and Future Directions.

    • 2026-02-02
    • Review
    • Nutrients 18(3)
    • • Zhengxin Zhao
      • Shengwei Zhao
      • Wenli Li
      • Zheng Lai
      • Yang Zhou
      • Feng Guan
      • Xu Liang
      • Jiawei Zhang
      • Linding Wang

    • PubMed: 41683324
    • DOI: 10.3390/nu18030502

    3 Insights on

    • Improved Endurance
    • Improved Gut Barrier Function
    • Reduced Fatigue

    • Moderate evidence
    • Rigorous Journal

  • Strain-Specific Systematic Review with Meta-Analysis of Probiotics Efficacy in the Treatment of Irritable Bowel Syndrome.

    • 2026-02-02
    • Review · n = 2,643
    • Journal of clinical medicine 15(3)
    • • Roman Maslennikov
      • Eva Gosteeva
      • Vera Ananeva
      • Lada Korshunova
      • Anastasya Kravtsowa
      • Elena Poluektova
      • Anatoly Ulyanin
      • Alexey Sigidaev
      • Patimat Kikhasurova
      • Vladimir Ivashkin

    • PubMed: 41682832
    • DOI: 10.3390/jcm15031152

    3 Insights on

    • Improved Quality of Life
    • Improved Irritable Bowel Syndrome Symptoms
    • Improved Irritable Bowel Syndrome Symptom Severity

    • High evidence

  • Protective activity of galacto-oligosaccharides against intestinal damage and inflammation induced by enterotoxigenic Escherichia coli F4+ and evaluation of prebiotic potential.

    • 2026-02-02
    • Frontiers in veterinary science 12
    • • Barbara Guantario
      • Sofie Tanghe
      • Alberto Finamore
      • Bert Devriendt
      • Chiara Devirgiliis
      • Stefanie Verstringe
      • Enya Rooyackers
      • Maartje De Vos
      • Jan Vande Ginste
      • Marianna Roselli

    • PubMed: 41705115
    • DOI: 10.3389/fvets.2025.1740099

    1 Insight on

    • Improved Prebiotic Support for Lactobacillus amylovorus

    • Low evidence
• February 3

  • Efficacy and safety of probiotic/synbiotic supplementation for osteoporosis: a meta-analysis of randomized controlled trials.

    • 2026-02-03
    • Systematic Review · n = 732
    • Frontiers in medicine 13
    • • Xinyu Wang
      • Lei Zhou
      • Xingming Yu
      • Qiang Hou
      • Chenglong Wang
      • Wei Cui
      • Yuheng Hu
      • Xiumei Wang
      • Zhuangchen Zhu

    • PubMed: 41709910
    • DOI: 10.3389/fmed.2026.1731528

    4 Insights on

    • Reduced Incidence of Adverse Events
    • Improved Bone Mass Density
    • Reduced Parathyroid Hormone Levels
    • Stable Lumbar Bone Mineral Density

    • High evidence

  • Probiotics as emerging adjuncts in metabolic associated fatty liver disease therapy-a systemic review.

    • 2026-02-03
    • Systematic Review
    • BMC gastroenterology 26(1)
    • • Radha Samyuktha Reddy Narem
      • Vani Mathakala
      • Sri Tejaswi Sallabathula
      • Vijaya Lakshmi Peddiboyina
      • Uma Maheswari Devi Palempalli

    • PubMed: 41634593
    • DOI: 10.1186/s12876-026-04618-7

    5 Insights on

    • Improved Lipid Metabolism
    • Reduced Hepatic Inflammation
    • Improved Insulin Resistance
    • Improved Liver Enzyme Function
    • Improved Liver Enzyme Activity

    • High evidence

  • Effect of a gut commensal Lactobacillus strain Limosilactobacillus caviae JL20 on leptospiral whole-cell inactivated vaccine in hamsters.

    • 2026-02-03
    • PLoS neglected tropical diseases 20(2)
    • • Shilei Zhang
      • Lianjie Ma
      • Qi Cao
      • Meijing Zhang
      • Guixin Yan
      • Wanqi Jiang
      • Xufeng Xie
      • Wenlong Zhang
      • Yongguo Cao

    • PubMed: 41632794
    • DOI: 10.1371/journal.pntd.0013951

    5 Insights on

    • Increased Immune System Activation
    • Improved Immune Response to Vaccination
    • Increased Antigen-Presenting Cell Activation
    • Increased T Cell Activation
    • Increased B Cell Activation

    • Low evidence
    • Animal Study

  • Targeted Lipidomics and Lipid Metabolism Elucidate Anti-Obesity Effects of Lactic Acid Bacteria-Fermented Purple Sweet Potato Tainung No. 73 Extract in Obese Mice.

    • 2026-02-03
    • International journal of molecular sciences 27(3)
    • • Hsien-Yi Yang
      • Chien-Hsun Huang
      • Shang-Tse Ho
      • Hsin-Hui Su
      • Yen-Po Chen
      • Yung-Tsung Chen

    • PubMed: 41683924
    • DOI: 10.3390/ijms27031489

    4 Insights on

    • Improved Serum Lipids
    • Reduced Adipocyte Hypertrophy
    • Reduced Weight Gain
    • Reduced Hepatic Lipid Accumulation

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Oncolytic Probiotics with Molecular Pili for Solid Tumor Therapy.

    • 2026-02-03
    • Advanced science (Weinheim, Baden-Wurttemberg, Germany) 13(19)
    • • Haodong Ge
      • Chengsheng Ding
      • Xiao Yang
      • Si Gao
      • Changjie Yang
      • Yuchen Hou
      • Hongye Wang
      • Linke Bian
      • Hao Zhong
      • Yifan Qu
      • Luyang Zhang
      • Junjun Ma
      • Zhengwei Cai
      • Wenguo Cui
      • Minhua Zheng

    • PubMed: 41632211
    • DOI: 10.1002/advs.202517989

    2 Insights on

    • Reduced Tumor Growth
    • Increased Intratumoral Accumulation

    • Low evidence

  • Bio-Functional Properties of Lactic Acid Bacteria in Functional Foods.

    • 2026-02-03
    • Review
    • Foods (Basel, Switzerland) 15(3)
    • • Svetoslav Dimitrov Todorov

    • PubMed: 41683114
    • DOI: 10.3390/foods15030528

    8 Insights on

    • Improved Gut Microbiota Composition
    • Improved Gastrointestinal Health
    • Improved Gut Microbiota Balance
    • Improved Digestive Health
    • Reduced Inflammation
    • Reduced Oxidative Stress
    • Improved Blood Lipid Profile
    • Improved Glycemia

    • Low evidence

  • Proteomic antibacterial characterization of flavonoid xanthohumol and probiotic Clostridium butyricum on pathogenic Clostridioides difficile.

    • 2026-02-03
    • Chinese medicine 21(1)
    • • Shenkun Wei
      • Guorong Li
      • Qiong Yang
      • Xinping Zhu
      • Junjie Liang
      • Mengyi Liu
      • Zijian Chen
      • Xia Liu
      • Jun-Yu Xu
      • Wei Chen

    • PubMed: 41634763
    • DOI: 10.1186/s13020-026-01343-x

    2 Insights on

    • Reduced Bacterial Toxin Production
    • Reduced Clostridium difficile Cytotoxicity

    • Low evidence
• February 4

  • The Protective Effect of Vitamin C Targeting Oxidative Stress on Renal Function in Patients with Septic Acute Kidney Injury: A Prospective, Randomized Controlled, Pilot Study.

    • 2026-02-04
    • RCT · n = 40
    • International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 96(1)
    • • Yu Chen
      • Min Lu
      • Xuee Shi
      • Fang Feng
      • Jinquan Zhou

    • PubMed: 41873106
    • DOI: 10.31083/ijvnr38770

    5 Insights on

    • Reduced Mortality Rate
    • Reduced Intensive Care Unit Stay
    • Reduced Acute Kidney Injury
    • Reduced Use of Vasoactive Drugs
    • Reduced Need for Continuous Renal Replacement Therapy

    • High evidence

  • The Role of Probiotics Limosilactobacillus reuteri, Ligilactobacillus salivarius, and Lactobacillus johnsonii in Inhibziting Pathogens, Maintaining Gut Health, and Improving Disease Outcomes.

    • 2026-02-04
    • Review
    • International journal of molecular sciences 27(3)
    • • Li Li
      • Xiangqi Qiu
      • Shengyong Lu
      • Haitao Yu
      • Panpan Lu
      • Sumei Zeng
      • Aihua Deng
      • Min Zhu
      • E Xu
      • Jin Niu

    • PubMed: 41683964
    • DOI: 10.3390/ijms27031545

    8 Insights on

    • Reduced Intestinal Inflammation
    • Improved Gut Health
    • Reduced Pathogenic Load
    • Improved Intestinal Health
    • Improved Clinical Outcomes
    • Reduced Pathogen Colonization
    • Improved Bone Health
    • Reduced Risk of Infection

    • Moderate evidence
    • Rigorous Journal

  • Microstructural and Rheological Properties of Camel and Bovine Milk Fermented with Five Lactic Acid Bacteria Strains.

    • 2026-02-04
    • Foods (Basel, Switzerland) 15(3)
    • • Sifatun Nesa Ali
      • Syed Muhammad Asim
      • Nadiya Samad
      • Mutamed Ayyash
      • Afaf Kamal-Eldin

    • PubMed: 41683133
    • DOI: 10.3390/foods15030546

    1 Insight on

    • Increased Proteolysis

    • Low evidence
• February 5

  • Exploring the Diversity and Applications of Lactic Acid Bacteria from Tunisian Traditional Fermented Foods.

    • 2026-02-05
    • Review
    • Microorganisms 14(2)
    • • Sabrine Alebidi
      • Hana Mallek
      • Mariagiovanna Fragasso
      • Vittorio Capozzi
      • Ferid Abidi
      • Ines Essid
      • Giuseppe Spano
      • Hiba Selmi

    • PubMed: 41753670
    • DOI: 10.3390/microorganisms14020383

    1 Insight on

    • Not Assessable From Provided Abstract

    • Low evidence

  • Combined fortification of yogurt with grape pomace pectic oligosaccharides and encapsulated probiotics.

    • 2026-02-05
    • Scientific reports 16(1)
    • • Mohamad Savarolyia
      • Sara Amiri Samani
      • Mina Ghorbani
      • Maedeh Khezri
      • Milad Kazemi
      • Manochehr Momeni Shahraki
      • Faramarz Khodaiyan
      • Seyed Saeid Hosseini

    • PubMed: 41644652
    • DOI: 10.1038/s41598-026-35862-2

    1 Insight on

    • Improved Antioxidant Activity

    • Low evidence
    • Rigorous Journal

  • Ginkgo biloba for cognitive impairment and dementia.

    • 2026-02-05
    • Meta-Analysis · n = 9,783
    • The Cochrane database of systematic reviews 2026(2)
    • • Lisa S Wieland
      • Emilie Ludeman
      • Yuan Chi
      • Termeh M Feinberg
      • I-Hui Chen
      • Kee-Hsin Chen
      • Yanan Zhu
      • Emma Wolverson
      • Hakima Amri

    • PubMed: 41641880
    • DOI: 10.1002/14651858.cd013661.pub2

    3 Insights on

    • Improved Activities of Daily Living
    • Improved Cognition
    • Improved Global Clinical Status

    • High evidence

  • Fermentation of Fruit By-Products as a Tool for Nutritional and Environmental Sustainability.

    • 2026-02-05
    • Review
    • Foods (Basel, Switzerland) 15(3)
    • • Doheon Kim
      • Uyory Choe
      • Young-Jin Park

    • PubMed: 41683164
    • DOI: 10.3390/foods15030578

    7 Insights on

    • Increased Antioxidant Activity
    • Improved Antioxidant Capacity
    • Increased Antioxidant Capacity
    • Enhanced Nutrient Utilization
    • No Human Health Outcome Reported
    • Increased Total Polyphenol Content
    • Improved Nutritional Value

    • Low evidence

  • Changes of Swede Score in Low-Grade Cervical Precancerous Lesions After Administration of Coriolus versicolor Vaginal Gel: A Prospective Single-Arm Pilot Study in Indonesia.

    • 2026-02-05
    • Observational
    • International journal of women's health 18
    • • Sulaeman Andrianto Susilo
      • Ali Budi Harsono

    • PubMed: 41883943
    • DOI: 10.2147/ijwh.s572630

    2 Insights on

    • Reduced Swede Score
    • Reduced VIA Positivity

    • Low evidence
• February 6

  • Effects of probiotics on blood lipids, glucose and pressure in patients with coronary heart disease: a systematic review and meta-analysis.

    • 2026-02-06
    • Review · n = 478
    • Frontiers in cardiovascular medicine 13
    • • Yan Zhong
      • Xinyu Yang
      • Weiming Kong
      • Yaru Shi
      • Weixiong Jian

    • PubMed: 41725935
    • DOI: 10.3389/fcvm.2026.1707408

    6 Insights on

    • Reduced LDL Cholesterol
    • Reduced Insulin Levels
    • Reduced Fasting Blood Glucose Levels
    • Reduced Total Cholesterol
    • Increased High-Density Lipoprotein Cholesterol
    • No Significant Change in Blood Pressure

    • High evidence

  • Curcumin Supplementation in Critically Ill Patients: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trial.

    • 2026-02-06
    • Meta-Analysis · n = 691
    • Phytotherapy research : PTR 40(4)
    • • Seyyed Mostafa Arabi
      • Ali Mollahasni
      • Abolfazl Azarian
      • Mahla Chambari
      • Leila Sadat Bahrami
      • Amirhossein Sahebkar

    • PubMed: 41652864
    • DOI: 10.1002/ptr.70238

    6 Insights on

    • Increased Serum Albumin Levels
    • Reduced Alanine Transaminase Level
    • Reduced Total Bilirubin Level
    • Reduced SOFA Score
    • Reduced Intensive Care Unit Stay Duration
    • Increased Alkaline Phosphatase Level

    • High evidence

  • Cross-stress adaptation enhances the survival and stability of freeze-dried lactic acid bacteria.

    • 2026-02-06
    • Food science of animal resources 46(1)
    • • Pin Chen
      • Chenjie Guo
      • Huan Cheng
      • Xingqian Ye
      • Jianle Chen

    • PubMed: 41821971
    • DOI: 10.1007/s44463-025-00007-y

    1 Insight on

    • Preserved Membrane Integrity

    • Low evidence
• February 8

  • Bifidobacterium Breve Yang08 Alleviates Atopic Dermatitis By Enriching Akkermansia Muciniphila and Inhibiting Neutrophil Extracellular Traps Formation In Mice.

    • 2026-02-08
    • Advanced science (Weinheim, Baden-Wurttemberg, Germany) 13(20)
    • • Yanqiang Shi
      • Shuang He
      • Chengyi Li
      • Hung Chan
      • Zhenfeng Liu
      • Bin Yang
      • Qing Li

    • PubMed: 41655253
    • DOI: 10.1002/advs.202518588

    3 Insights on

    • Reduced Atopic Dermatitis Severity
    • Restored Gut Microbiota
    • Reduced Neutrophil Extracellular Trap Formation

    • Low evidence
• February 10

  • Lactiplantibacillus plantarum GUANKE ameliorates influenza a virus-induced inflammation and lung barrier dysfunction through enhancing mitophagy and improving oxidative phosphorylation.

    • 2026-02-10
    • Cellular and molecular life sciences : CMLS 83(1)
    • • Simin Lu
      • Kun Yue
      • Siqin He
      • Jielan Mi
      • Tao Yang
      • Yuewen Yang
      • Hanyu Ma
      • Zhihong Ren
      • Lili Ren
      • Jianguo Xu

    • PubMed: 41667656
    • DOI: 10.1007/s00018-026-06081-9

    2 Insights on

    • Reduced Lung Inflammation
    • Improved Lung Barrier Function

    • Low evidence

  • Moringa oleifera Lamk. as a Promising Adjunct Therapeutic Candidate: A Narrative Review of Human Studies and Published Case Reports.

    • 2026-02-10
    • Systematic Review · n = 22
    • Drug design, development and therapy 20
    • • Erlia Anggrainy Sianipar
      • Sri Adi Sumiwi
      • Yasmiwar Susilawati
      • Jutti Levita

    • PubMed: 41710586
    • DOI: 10.2147/dddt.s586556

    5 Insights on

    • Improved Immune Function
    • Improved Total Antioxidant Status
    • Improved Glycemia
    • Improved Vitamin A Content
    • Improved Nutritional Outcome

    • High evidence

  • Triplex viability PCR for simultaneous quantification of Lactobacillus acidophilus, Streptococcus thermophilus, and Bifidobacterium bifidum in live microbial formulations.

    • 2026-02-10
    • Frontiers in microbiology 17
    • • Luca Del Pio
      • Stefania Catone
      • Giulio Pisani
      • Giovanna Franciosa

    • PubMed: 41743130
    • DOI: 10.3389/fmicb.2026.1759060

    1 Insight on

    • Improved Detection of Live Microorganisms in Probiotic Formulations

    • Low evidence

  • Tongue brushing and oral probiotics for the treatment of halitosis: a randomized controlled trial.

    • 2026-02-10
    • RCT · n = 80
    • Journal of breath research 20(1)
    • • Li Mei
      • Fay Yan
      • Lei Cheng
      • Aishah Na
      • Richard D Cannon
      • Guangzhao Guan

    • PubMed: 41604763
    • DOI: 10.1088/1752-7163/ae3edc

    2 Insights on

    • Reduced Halitosis
    • Improved Self-reported Halitosis Score

    • High evidence
• February 11

  • Limosilactobacillus fermentum SPC L75-1: a novel sourdough starter enhancing bread quality and exhibiting postbiotic immunomodulatory activity.

    • 2026-02-11
    • BMC microbiology 26(1)
    • • Min Jeong Kwak
      • Seul-Ah Kim
      • Seo Hyun Lim
      • Geonhee Kim
      • Seongwon Cheon
      • Seongbong Song
      • Sangmin Shim
      • Sungho Lee
      • Nam Soo Han

    • PubMed: 41673804
    • DOI: 10.1186/s12866-026-04723-3

    3 Insights on

    • Increased Antioxidant Activity
    • Reduced Inflammation
    • Improved Food Safety

    • Low evidence

  • Effect of Bifidobacterium longum on cognition and microbiota in post-stroke patients: a single-blinded, controlled trial.

    • 2026-02-11
    • RCT · n = 22
    • International journal of medical sciences 23(3)
    • • Shu-Ting Lin
      • Te-Hsuan Tung
      • Yen-Nung Lin
      • Feng-Hang Chang
      • Yu Zhi Lian
      • Chien-Hung Lai
      • Tsan-Hon Liou
      • Chi-Chang Huang
      • Ya-Ling Chen
      • Jane C-J Chao

    • PubMed: 41799757
    • DOI: 10.7150/ijms.124024

    3 Insights on

    • Improved Cognitive Function
    • No Improvement in Physical Performance
    • Reduced Nutritional Status

    • High evidence
• February 12

  • Collection of human bacteria at University of Tartu, Estonia.

    • 2026-02-12
    • Microbiology resource announcements 15(2)
    • • Reet Mändar
      • Hugo Mändar
      • Tiiu Rööp
      • Marika Mikelsaar

    • PubMed: 41432456
    • DOI: 10.1128/mra.00758-25

    5 Insights on

    • Improved Gut Microbiota Composition
    • Improved Gastrointestinal Health
    • Improved Total Antioxidant Status
    • Reduced Oxidative Stress
    • Improved Gastrointestinal Symptoms

    • Low evidence

  • Lactobacillus fermentum supplementation modulates jejunal microbiota, metabolome, and morphology in yaks under high-energy feeding.

    • 2026-02-12
    • RCT
    • Animal microbiome 8(1)
    • • Qinran Yu
      • Chun Huang
      • Pengjia Bao
      • Ning Li
      • Minghao Zhang
      • Tong Wang
      • Chaofan Ma
      • Jingying Deng
      • Xinyu Cao
      • Jianlei Jia
      • Ping Yan

    • PubMed: 41680945
    • DOI: 10.1186/s42523-025-00479-9

    5 Insights on

    • Improved Intestinal Morphology
    • Improved Growth Performance
    • Increased Short-Chain Fatty Acid Production
    • Reduced Intestinal Damage
    • Improved Gut Barrier Morphology

    • High evidence

  • The Therapeutic Effect of Garlic Supplements on the Metabolic Profile of Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

    • 2026-02-12
    • Review
    • Nutrition and metabolic insights 19
    • • Anahita Ebrahimzadeh
      • Mohammad Safargar
      • Milad Rajabzadeh-Dehkordi
      • Faezeh Nematolahi
      • Mahsa Samadani
      • Laya Saeid
      • Abbas Mohtashamian
      • Mohammad Ali Izadi
      • Armin Ebrahimzadeh
      • Ali Reza Safarpour

    • PubMed: 41695233
    • DOI: 10.1177/11786388251413660

    6 Insights on

    • Reduced Triglyceride Levels
    • Reduced LDL Cholesterol
    • Reduced Hemoglobin A1c
    • Reduced Total Cholesterol
    • Increased HDL Cholesterol
    • Reduced Fasting Blood Glucose

    • Low evidence

  • Microbial biofortification of fermented foods: a review of probiotic-mediated nutrient enhancement.

    • 2026-02-12
    • Review
    • Frontiers in nutrition 13
    • • Fahad Saad Alhodieb

    • PubMed: 41769659
    • DOI: 10.3389/fnut.2026.1754233

    4 Insights on

    • Improved Immune Function
    • Improved Gut Microbiota Balance
    • Improved Micronutrient Status
    • Reduced Antinutrient Levels

    • Low evidence

  • Effectiveness of Lactobacillus reuteri Probiotics on Plaque Index, Gingival Index, and Bleeding on Probing in Adolescents with Betel Quid Chewing Habit: Study in Children Aged 13-15 Years in Alor Regency, East Nusa Tenggara.

    • 2026-02-12
    • Observational
    • International journal of clinical pediatric dentistry 19(2)
    • • Labiba Idzni Marjani
      • Margaretha Suharsini
      • Eva Fauziah

    • PubMed: 41800014
    • DOI: 10.5005/jp-journals-10005-3411

    4 Insights on

    • Reduced Gingival Index
    • Reduced Bleeding on Probing (BOP)
    • Reduced Gingival Inflammation
    • Reduced Plaque Index

    • Low evidence
• February 13

  • Comparison Between Natural Products and Chlorhexidine in Non-Surgical Periodontal Therapy: A Systematic Review of Randomized Clinical Trials.

    • 2026-02-13
    • Review
    • Dentistry journal 14(2)
    • • Andrea Scribante
      • Matteo Pellegrini
      • Maurizio Pascadopoli
      • Valentino Natoli
      • Valentina Poma
      • Andrea Butera

    • PubMed: 41744948
    • DOI: 10.3390/dj14020110

    4 Insights on

    • Reduced Probing Pocket Depth
    • Reduced Bleeding on Probing (BOP)
    • Improved Clinical Attachment
    • Reduced Plaque Index

    • Low evidence

  • Rhubarb enhances gastrointestinal motility via calcium-mediated intestinal acetylcholine release: a network pharmacology study.

    • 2026-02-13
    • RCT
    • Scientific reports 16(1)
    • • Zhiyong Wen
      • Weihua Liu
      • Jialing Li
      • Songling Tan
      • Jianbo Wen

    • PubMed: 41688541
    • DOI: 10.1038/s41598-026-39372-z

    1 Insight on

    • Increased Bowel Movements

    • High evidence
    • Rigorous Journal

  • Bifidobacterium breve promotes growth and lipid alteration in Trichomonas vaginalis transiently through transcriptomic reprogramming.

    • 2026-02-13
    • Scientific reports 16(1)
    • • Pei-Yun Chen
      • Yuan-Ming Yeh
      • Chun-Hsien Chen
      • Ming-Chi Li
      • Yu-Tzu Hsu
      • Po-Jung Huang
      • Wei-Hung Cheng

    • PubMed: 41688526
    • DOI: 10.1038/s41598-026-38866-0

    3 Insights on

    • Altered Lipid Metabolism
    • Increased Trichomonas Vaginalis Growth
    • No Protection of Host Epithelial Cells

    • Low evidence
    • Rigorous Journal
• February 14

  • [Probiotics' position in clinical practice: focus on the combination of Lactobacillus acidophilus (LA-5) and Bifidobacterium animalis subsp. lactis (BB-12). A review].

    • 2026-02-14
    • Review
    • Terapevticheskii arkhiv 97(12)
    • • A V Gorelov
      • R S Kozlov
      • I V Andreeva
      • A A Arova
      • I A Bavykina
      • M S Grigorovich
      • E V Dovgan
      • K D Ermolenko
      • O V Zaytseva
      • S M Zakharenko
      • V V Zelenskaia
      • S K Zyryanov
      • N A Ilyenkova
      • M A Kachkovskii
      • T A Kogut
      • E G Kondyurina
      • V V Krasnov
      • E E Lokshina
      • V F Privorotsky
      • M N Repetskaya
      • M F Rzyankina
      • S N Serikova
      • O U Stetsiouk
      • D V Usenko
      • L V Khanipova
      • A M Shabalov
      • M A Shevyakov
      • L V Yakovleva

    • PubMed: 41705617
    • DOI: 10.26442/00403660.2025.12.203481

    2 Insights on

    • Reduced Antibiotic-Associated Diarrhea
    • Increased Helicobacter pylori Eradication Rate

    • Low evidence

  • Combining Lactiplantibacillus plantarum and Bifidobacterium adolescentis can improve GABA production in faecal fermentations.

    • 2026-02-14
    • Journal of applied microbiology 137(3)
    • • Rihua Xu
      • Melinda J Mayer
      • Mark Philo
      • Gwénaëlle Le Gall
      • Guesh Mulaw
      • Alise Ponsero
      • Arjan Narbad

    • PubMed: 41689511
    • DOI: 10.1093/jambio/lxag047

    3 Insights on

    • Increased Short-Chain Fatty Acid Production
    • Increased GABA Production
    • Reduced Escherichia Abundance

    • Low evidence
• February 15

  • Photoprotection for Skin Cancer: What's New.

    • 2026-02-15
    • Review
    • Cancers 18(4)
    • • Yolanda Gilaberte
      • Andrés Ederra-Galé
      • Juan J García-Alfonso
      • Tamara Gracia-Cazaña

    • PubMed: 41749887
    • DOI: 10.3390/cancers18040634

    2 Insights on

    • Reduced Actinic Keratoses
    • Reduced Actinic Damage

    • Low evidence

  • Bifidobacterium animalis subsp. lactis BLa80 for preventing allergic, respiratory, and gastrointestinal diseases in young children in China: a randomized double-blind placebo-controlled trial.

    • 2026-02-15
    • RCT · n = 180
    • Clinical and experimental pediatrics 69(2)
    • • Ke Chen
      • Xi Zhang
      • Kaihong Zeng
      • Jiayi Zhong
      • Shanshan Jin
      • Yang Nie
      • Ping Yang
      • Nianyang He
      • Haixia Chen
      • Yanmei Cao
      • Yunrong Fu
      • Ziji Fang
      • Wei Jiang
      • Changqi Lium

    • PubMed: 41167178
    • DOI: 10.3345/cep.2025.01256

    8 Insights on

    • Improved Gut Microbiota
    • Reduced Upper Respiratory Tract Infection Days
    • Reduced Upper Respiratory Infections
    • Improved Gut Microbiome Composition
    • Reduced Tracheitis
    • Reduced Eczema Incidence
    • Reduced Fecal Immune Biomarkers
    • Reduced Eczema Morbidity

    • High evidence
• February 16

  • Oral Administration of Lactobacillus amylovorus Alleviates Diarrhea by Restoring Gut Microbiota and SCFAs in Neonatal Goats.

    • 2026-02-16
    • Clinical Trial · n = 20
    • Animals : an open access journal from MDPI 16(4)
    • • Mudathir Y Abdulrahman
      • Nasir A Ibrahim
      • Mohamed Osman Abdalrahem Essa
      • Saber Y Adam
      • Raza Mohai Ud Din
      • Rifat Ullah Jan
      • Nosiba S Basher
      • Mokhtar Rejili
      • Shaaban S Elnesr
      • Ahmed A Saleh
      • Hosameldeen Mohamed Husien
      • Mengzhi Wang

    • PubMed: 41751094
    • DOI: 10.3390/ani16040633

    4 Insights on

    • Improved Gut Microbiota Diversity
    • Reduced Diarrhea Symptoms
    • Increased Short-Chain Fatty Acid Production
    • Reduced Diarrhea Severity

    • Moderate evidence

  • Probiotic intervention not beneficial to prevent antibiotic-associated diarrhea in absence of antibiotic-induced microbiome disruption.

    • 2026-02-16
    • RCT
    • Scientific reports 16(1)
    • • Daniel Merenstein
      • Silvia Grant-Beurmann
      • Mary Ellen Sanders
      • Tina Tan
      • Brendan Burke
      • Aneesha Kumar
      • Keisha Herbin-Smith
      • Jessy Sparenborg
      • Frank D'Amico
      • Bob Roberts
      • Claire Fraser

    • PubMed: 41699149
    • DOI: 10.1038/s41598-026-39826-4

    2 Insights on

    • Reduced Antibiotic-Associated Diarrhea
    • Reduced Antibiotic-Associated Gut Microbiome Disruption

    • High evidence
    • Rigorous Journal

  • Lactobacillus acidophilus KBL409 improves serum indoxyl sulfate via gut microbial changes in a human study.

    • 2026-02-16
    • RCT · n = 34
    • NPJ science of food 10(1)
    • • Sung Jae Jang
      • SungJun Park
      • Kiuk Lee
      • Woon-Ki Kim
      • Sung Hyun Moon
      • Bo-Ram Cho
      • Cheonghoon Lee
      • Hyungjin Lee
      • Tae-Wook Nam
      • GwangPyo Ko

    • PubMed: 41698905
    • DOI: 10.1038/s41538-026-00755-1

    1 Insight on

    • Reduced Indoxyl Sulfate Levels

    • High evidence
• February 17

  • Prebiotics, probiotics, and synbiotics and maternal mental health during pregnancy and postpartum period: a systematic review.

    • 2026-02-17
    • Systematic Review · n = 342
    • Frontiers in nutrition 13
    • • Sandra Martín-Peláez
      • Luis Miguel Martín-delosReyes
      • Naomi Cano-Ibáñez

    • PubMed: 41783815
    • DOI: 10.3389/fnut.2026.1776398

    4 Insights on

    • Reduced Depression Symptoms
    • Reduced Anxiety Symptoms
    • Reduced Anxiety
    • Reduced Depressive Symptoms Postpartum

    • High evidence

  • Adjunctive probiotic therapy sustains symptom relief in gastroesophageal reflux disease through gut microbiome-metabolome remodeling.

    • 2026-02-17
    • RCT
    • mSystems 11(2)
    • • Yingmeng Li
      • Qiong Li
      • Keyu Quan
      • Yong Xie
      • Ni Yang
      • Teng Ma
      • Longjin Zheng
      • Wei Zhou
      • Yalin Li
      • Hao Jin
      • Zhihong Sun
      • Yongfu Chen
      • Lai-Yu Kwok
      • Nonghua Lu
      • Weifeng Zhu
      • Wenjun Liu
      • Heping Zhang

    • PubMed: 41609355
    • DOI: 10.1128/msystems.01568-25

    8 Insights on

    • Improved Gut Microbiome Composition
    • Improved Gastrointestinal Symptoms
    • Increased Levels of Beneficial Metabolites
    • Increased Production of Bioactive Metabolites
    • Increased Beneficial Gut Microbiota Abundance
    • Reduced Reflux Symptoms
    • Improved Gastroesophageal Reflux Symptoms
    • Improved Endoscopic Healing in GERD

    • High evidence
    • Rigorous Journal

  • Essential micronutrients and biguanides (metformin) synergistic and antagonistic interactions on neurocognitive outcomes in type two diabetes mellitus: a systematic review of preclinical and clinical evidence.

    • 2026-02-17
    • Systematic Review
    • Frontiers in endocrinology 17
    • • Herbert Izo Ninsiima
      • Herbert E Ainamani
      • Geoffrey Ayebazibwe
      • Daniel Matovu
      • Ejike Daniel Eze

    • PubMed: 41782745
    • DOI: 10.3389/fendo.2026.1764157

    3 Insights on

    • Improved Insulin Sensitivity
    • Reduced Plasma Glucose Levels
    • Improved HbA1c

    • High evidence

  • Prebiotics, Probiotics, and Postbiotics for Acne Vulgaris: A Systematic Review.

    • 2026-02-17
    • Systematic Review
    • Dermatology and therapy 16(3)
    • • Peyton V Warp
      • Sophie M Bilik
      • Lina M Ferrari
      • Jonette E Keri

    • PubMed: 41703218
    • DOI: 10.1007/s13555-026-01659-4

    6 Insights on

    • Improved Tolerability
    • Good Tolerability
    • Absence of Serious Adverse Events
    • Reduced Acne Severity
    • Reduced Acne Lesions
    • Favorable Safety Profile

    • High evidence

  • Preventing Contrast-Induced Acute Kidney Injury in Egyptian Patients Undergoing Coronary Angiography: A Randomized Controlled Trial.

    • 2026-02-17
    • RCT · n = 120
    • Clinical drug investigation 46(4)
    • • Sarah Sabry
      • Mai K Ammar
      • Mahmoud Taeima
      • Noha Nassar
      • Azza ElFiky
      • Ayman Saleh

    • PubMed: 41701447
    • DOI: 10.1007/s40261-026-01524-4

    1 Insight on

    • Reduced Contrast-Induced Acute Kidney Injury

    • High evidence
    • Large Human Trial
• February 18

  • Impact of Pediococcus acidilactici and tylvalosin on porcine Enterobacterales abundance, antimicrobial resistance, and conjugative potential.

    • 2026-02-18
    • Clinical Trial
    • Journal of applied microbiology 137(3)
    • • Annie Turcotte
      • Dominic Poulin-Laprade
      • Linda Saucier
      • Joanie Lemieux
      • Nathalie Gagnon
      • Sylvain Fournaise
      • Frédéric Guay
      • Vincent Burrus
      • Guylaine Talbot

    • PubMed: 41707193
    • DOI: 10.1093/jambio/lxag044

    4 Insights on

    • Reduced Beta-Lactam Resistance
    • Reduced Cefotaxime-Resistant Enterobacterales Abundance
    • Increased Erythromycin-Resistant Enterobacterales Abundance in the Ileum
    • Reduced Erythromycin-Resistant Enterobacterales in Feces

    • Low evidence
    • Animal Study

  • Enhanced editing of Bifidobacterium lactis using the endogenous Type I-G CRISPR-Cas system.

    • 2026-02-18
    • Applied and environmental microbiology 92(2)
    • • Ourania Raftopoulou
      • Kendall Malmstrom
      • Meichen Pan
      • Rodolphe Barrangou

    • PubMed: 41524418
    • DOI: 10.1128/aem.01839-25

    1 Insight on

    • No Human Health Outcome Reported

    • Low evidence

  • Transcriptomic responses of Saccharomyces boulardii to the germ-free mouse gut.

    • 2026-02-18
    • BMC genomics 27(1)
    • • Genan Wang
      • Deniz Durmusoglu
      • Nathan Crook

    • PubMed: 41709131
    • DOI: 10.1186/s12864-026-12661-7

    1 Insight on

    • Altered Gut Microbial Transcriptomic Response

    • Low evidence

  • In vitro digestion and fermentation of ginseng pectic polysaccharide GPS-1 and attenuation of its product on oleic acid-induced oxidative stress in HepG2 cells.

    • 2026-02-18
    • Frontiers in pharmacology 17
    • • Xiwen Sun
      • Li Liu
      • Wenbo Jiao
      • Ting Ren
      • Ran Zhao
      • Zirui Tan
      • Ziye Jiang
      • Jing Wang
      • Bo Li
      • Xiaoyu Zhang
      • Lili Jiao

    • PubMed: 41788794
    • DOI: 10.3389/fphar.2026.1758770

    3 Insights on

    • Reduced Liver Lipid Accumulation
    • Increased Short-Chain Fatty Acid Production
    • Improved Total Antioxidant Status

    • Low evidence
• February 19

  • Maternal gut microbiota mediates prenatal stress-induced fetal blood‒brain barrier dysfunction.

    • 2026-02-19
    • Gut microbes 18(1)
    • • Xuanping Wang
      • Fang-Yue Zhou
      • Ting Wu
      • Chenchi Duan
      • Xukai Luo
      • Yicong Meng
      • He-Feng Huang
      • Yan-Ting Wu

    • PubMed: 41715909
    • DOI: 10.1080/19490976.2026.2631242

    1 Insight on

    • Reduced Fetal Blood-Brain Barrier Dysfunction

    • Low evidence
    • Animal Study

  • Exopolysaccharides of Lactobacillus crispatus mediate key balancing interactions with the vaginal mucosa.

    • 2026-02-19
    • NPJ biofilms and microbiomes 12(1)
    • • Vanessa Croatti
      • Caroline Dricot
      • Tom Eilers
      • Jelle Dillen
      • Tim Van Rillaer
      • Eline Cauwenberghs
      • Ilke Van Tente
      • Sam Bakelants
      • Dieter Vandenheuvel
      • Camille Allonsius
      • Isabel Pintelon
      • Sofie Thys
      • Wendy Mensah
      • Marina Naldi
      • Peter A Bron
      • Stijn Wittouck
      • Irina Spacova
      • Carola Parolin
      • Beatrice Vitali
      • Sarah Lebeer

    • PubMed: 41714642
    • DOI: 10.1038/s41522-026-00937-5

    3 Insights on

    • Improved Immune Regulation
    • Improved Immune Surveillance
    • Reduced Vaginal Inflammation

    • Low evidence

  • Therapeutic potential of L-carnitine in coronary artery disease: a systematic review.

    • 2026-02-19
    • Systematic Review · n = 21
    • Inflammopharmacology 34(3)
    • • Rehab H Werida
      • Sherouk M Okda

    • PubMed: 41709059
    • DOI: 10.1007/s10787-025-02048-7

    3 Insights on

    • Reduced Inflammatory Markers
    • Reduced All-Cause Mortality
    • Improved Blood Lipid Profile

    • High evidence

  • Microbiota management: a perspective for kidney transplant patients.

    • 2026-02-19
    • Review
    • Frontiers in transplantation 5
    • • Cláudia Silva Souza
      • Niels Olsen Saraiva Camara
      • Thaís Alves-Silva

    • PubMed: 41798990
    • DOI: 10.3389/frtra.2026.1703048

    7 Insights on

    • Reduced Gastrointestinal Symptoms
    • Improved Gut Health
    • Improved Gut Microbiota Balance
    • Reduced Renal Inflammation
    • Improved Tolerance
    • Improved Kidney Allograft Acceptance
    • Improved Renal Function

    • Low evidence

  • Health benefits of Bifidobacterium animalis subsp. lactis BB-12 in infants and children: a mini-review.

    • 2026-02-19
    • Review
    • Frontiers in microbiology 17
    • • Carlos Patricio Acosta Rodríguez Bueno
      • Ailim Carias Domínguez
      • Denis Guyonnet
      • Etienne Pouteau

    • PubMed: 41800422
    • DOI: 10.3389/fmicb.2026.1773473

    8 Insights on

    • Improved Immune Function
    • Reduced Dysbiosis
    • Reduced Pathogenic Load
    • Improved Gut Microbiome Composition
    • Reduced Inflammation
    • Improved Immune Modulation
    • Improved Infant Gut Microbiome Development
    • Enhanced Bifidobacteria-Dominant Infant Gut Colonization

    • Low evidence
• February 20

  • Multi-omics reveals microbial community characteristics and flavonoid biotransformation mechanisms during mung bean sour fermentation.

    • 2026-02-20
    • Current research in food science 12
    • • Xunda Wang
      • Yuxia Yang
      • Yue Li
      • Ziqi Zhu
      • Reham Khashaba
      • Qinghua Yue

    • PubMed: 41717629
    • DOI: 10.1016/j.crfs.2026.101342

    2 Insights on

    • Enhanced Flavonoid Metabolism
    • Reduced Flavonoid Levels

    • Low evidence

  • Preload time-dependent effects of Panax ginseng on postprandial glucose tolerance. A randomized controlled study in healthy middle-aged participants.

    • 2026-02-20
    • Clinical Trial
    • Frontiers in nutrition 13
    • • Anne Nilsson

    • PubMed: 41798830
    • DOI: 10.3389/fnut.2026.1759162

    2 Insights on

    • Improved Insulin Levels
    • Reduced Postprandial Blood Glucose Level

    • High evidence

  • Effects of different vitamin D supplements on body fat distribution and glucolipid metabolism in patients with obesity-associated metabolic syndrome: A meta-analysis.

    • 2026-02-20
    • Meta-Analysis
    • Medicine 105(8)
    • • Qin Huang
      • Jidong Zhan
      • Yuan Gui
      • Ming Ma
      • E Li

    • PubMed: 41731803
    • DOI: 10.1097/md.0000000000047436

    4 Insights on

    • Improved Insulin Sensitivity
    • Reduced Visceral Fat
    • Reduced LDL Cholesterol
    • Reduced Fasting Blood Glucose Levels

    • High evidence

  • The role of bovine colostrum in feeding intolerance in preterm neonates: a systematic review and meta-analysis of randomized controlled trials.

    • 2026-02-20
    • Systematic Review · n = 670
    • Frontiers in nutrition 12
    • • Jia Yao
      • Bo Zheng
      • Jie Zhang
      • Fen Xu
      • Jianbo Zhuang

    • PubMed: 41798170
    • DOI: 10.3389/fnut.2025.1668500

    3 Insights on

    • Reduced Necrotising Enterocolitis
    • Reduced Time to Full Enteral Feeding
    • Reduced Feeding Intolerance

    • High evidence

  • Modulation of gut-heart axis by synbiotic (Lactiplantibacillus plantarum M10 and Isomaltose) in high cholesterol diet induced atherosclerotic murine model.

    • 2026-02-20
    • BMC microbiology 26(1)
    • • Siloni Patial
      • Khem Raj
      • Geeta Shukla

    • PubMed: 41721244
    • DOI: 10.1186/s12866-026-04840-z

    11 Insights on

    • Improved Glucose Tolerance
    • Reduced Hepatic Steatosis
    • Improved Gut Microbiome Composition
    • Reduced Inflammation
    • Reduced Oxidative Stress
    • Reduced Oxidative Stress Markers
    • Improved Gut Flora Modulation
    • Improved Blood Lipid Profile
    • Reduced Atherosclerosis Risk Factors
    • Increased Fecal Lipid Excretion
    • Reduced Aortic Thickness

    • Low evidence
• February 21

  • Effects of Probiotics in Pregnant Women with Gestational Diabetes Mellitus: An Overview of Systematic Reviews.

    • 2026-02-21
    • Review · n = 16
    • International journal of general medicine 19
    • • Huixia Ren
      • Naijin Zhang
      • Yonghui Li
      • Yingxiang Li
      • Mengyang Wang
      • Huaien Bu
      • Hongwu Wang

    • PubMed: 41756807
    • DOI: 10.2147/ijgm.s576626

    8 Insights on

    • Improved Insulin Sensitivity
    • Reduced Inflammation
    • Reduced Oxidative Stress
    • Reduced Plasma Glucose Levels
    • Improved Blood Lipid Profile
    • Improved Glycemia
    • Improved Neonatal Health Outcomes
    • Reduced Neonatal Risk

    • Low evidence

  • Surface Layer-Associated Protein on Nanoparticles from Lactobacillus helveticus Enhances the Response to LPS in RAW264.7 Cells.

    • 2026-02-21
    • Current microbiology 83(4)
    • • Chika Yamamoto
      • Nao Fujiwara
      • Ika Adhani Sholihah
      • Mana Yamamoto
      • Rinka Kizaki
      • Daichi Ito
      • Chinatsu Yokoi
      • Saho Furukawa
      • Hiroko Koyama
      • Yoko Hirata
      • Kyoji Furuta
      • Hiroshi Takemori

    • PubMed: 41721904
    • DOI: 10.1007/s00284-026-04783-8

    2 Insights on

    • Enhanced Immune Response
    • Increased Inflammatory Mediator Production

    • Low evidence
    • Animal Study

  • Probiotic and microbial modulation of polyamine production: an emerging avenue for neuroprotection in neurodegenerative disorders.

    • 2026-02-21
    • Review
    • Amino acids 58(1)
    • • Tushar Adhikari
      • Prerona Saha

    • PubMed: 41721117
    • DOI: 10.1007/s00726-026-03505-5

    6 Insights on

    • Reduced Neuroinflammation
    • Increased Polyamine Levels
    • Improved Antioxidant Defense
    • Improved Neuroprotection
    • Increased Polyamine Production
    • Reduced Neuroinflammatory Markers

    • Low evidence
• February 22

  • Therapeutic Potential and Mechanistic Pathways of Plant-Based Supplements and Exercise Training in Blood Pressure Management: An Evidence-Based Review and Research Agenda.

    • 2026-02-22
    • Review
    • Nutrients 18(4)
    • • Behzad Taati
      • Georgian Badicu
      • Jolita Vveinhardt

    • PubMed: 41754217
    • DOI: 10.3390/nu18040700

    1 Insight on

    • Reduced Blood Pressure

    • Moderate evidence
    • Rigorous Journal
• February 23

  • The effect of short-term consumption of Bifidobacterium bifidum on the gut microbiome of obese individuals.

    • 2026-02-23
    • Experimental biology and medicine (Maywood, N.J.) 251
    • • Inna Burakova
      • Yuliya Smirnova
      • Polina Morozova
      • Svetlana Pogorelova
      • Olga Kryukova
      • Tatiana Kislova
      • Olga Korneeva
      • Mikhail Syromyatnikov

    • PubMed: 41809656
    • DOI: 10.3389/ebm.2026.10894

    1 Insight on

    • Improved Gut Microbiome Composition

    • Low evidence

  • Advances in genome-scale metabolic modeling of Bacillus subtilis.

    • 2026-02-23
    • Review
    • Biotechnology letters 48(2)
    • • Pınar Kocabaş

    • PubMed: 41729311
    • DOI: 10.1007/s10529-026-03712-w

    1 Insight on

    • No Human Health Outcome Reported

    • Low evidence
• February 24

  • Harnessing a germ‑free mouse gut bioreactor for directed evolution of probiotics to combat non-alcoholic fatty liver disease.

    • 2026-02-24
    • Nature communications 17(1)
    • • Zhe Han
      • Zheng Sun
      • Xinlei Liu
      • Dongyu Zhen
      • Quan Guo
      • Leijie Zheng
      • Shuaiming Jiang
      • Zeng Zhang
      • Siyuan Shen
      • Jiachao Zhang

    • PubMed: 41735321
    • DOI: 10.1038/s41467-026-69823-0

    2 Insights on

    • Improved Liver Function
    • Improved Bile Acid Metabolism

    • Moderate evidence
    • Rigorous Journal

  • Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.

    • 2026-02-24
    • RCT
    • Nutrients 18(5)
    • • Yue Dou
      • Yaqing Wang
      • Wei Zhang
      • Yuewei Jiang
      • Jiyao Zhang
      • Tao Yang
      • Ziqi Han
      • Yaotong Li
      • Chang Liu
      • Dingmeng Ren

    • PubMed: 41829897
    • DOI: 10.3390/nu18050724

    14 Insights on

    • Improved Attention Span
    • Increased Hemoglobin Levels
    • Improved High-Intensity Intermittent Exercise Performance
    • Improved Repeated Sprint Ability
    • Reduced Blood Lactate
    • Improved Decision Accuracy
    • Improved Passing Performance
    • Improved Shooting Performance
    • Increased Match Total Running Distance
    • Increased High-Speed Running Distance
    • Improved Sprint Time
    • Improved Intermittent Exercise Performance
    • Improved Decision-Making Reaction Time Under Fatigue
    • Improved Decision-Making Accuracy

    • High evidence
    • Rigorous Journal

  • The Combination of Lactobacillus reuteri RC-14® and Lactobacillus rhamnosus GR-1® Induces Anxiolytic-like and Antidepressant-like Effects via Estrogenic Receptors in Ovariectomized Rats.

    • 2026-02-24
    • Nutrients 18(5)
    • • Gilberto-Uriel Rosas-Sánchez
      • León Jesús Germán-Ponciano
      • Juan Francisco Rodríguez-Landa
      • Herlinda Bonilla-Jaime
      • Ofelia Limón-Morales
      • José Luis Muñoz-Carrillo
      • María Isabel Pérez-Vega
      • César Soria-Fregozo

    • PubMed: 41829884
    • DOI: 10.3390/nu18050713

    3 Insights on

    • Reduced Anxiety-like Behavior
    • Reduced Depression-like Behavior
    • Estrogen Receptor-Mediated Effects

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Bifidobacterium infantis-a key (late) colonizer of the infant gut?

    • 2026-02-24
    • Clinical Trial
    • mSphere 11(2)
    • • Martin F Laursen

    • PubMed: 41586590
    • DOI: 10.1128/msphere.00851-25

    1 Insight on

    • Improved Gut Microbiota Colonization

    • Moderate evidence

  • Transient Mood Elevation Without a Manic Switch: Goldenseal-Augmented Oral Glutamatergic Regimen in Bipolar Depression With Comorbid Obsessive-Compulsive Disorder (OCD).

    • 2026-02-24
    • Case Report
    • Cureus 18(2)
    • • Ngo Cheung

    • PubMed: 41756342
    • DOI: 10.7759/cureus.104209

    3 Insights on

    • Increased Energy Levels
    • Improved Mood
    • Improved Work Performance

    • Low evidence

  • Tailored molecular weight hyaluronic acid production by engineered Lactococcus lactis.

    • 2026-02-24
    • Microbial cell factories 25(1)
    • • Sharath Soundiraraj
      • Nakul Ravishankar
      • Pandeeswari Jeeva
      • Lars M Blank
      • Guhan Jayaraman

    • PubMed: 41736074
    • DOI: 10.1186/s12934-026-02945-8

    2 Insights on

    • Increased Hyaluronic Acid Production
    • Increased Hyaluronic Acid Molecular Weight

    • Low evidence

  • Osteoporosis and gut microbiota: current understandings.

    • 2026-02-24
    • Review
    • Frontiers in immunology 17
    • • Yikai Liu
      • Shuai Lu
      • Ruifeng Bai
      • Pengli Han
      • Yejun Zha
      • Xieyuan Jiang

    • PubMed: 41816331
    • DOI: 10.3389/fimmu.2026.1761421

    3 Insights on

    • Increased Bone Mineral Density
    • Improved Bone Metabolism
    • Delayed Osteoporosis Progression

    • Low evidence

  • Encapsulation and Functional Activity of Lactobacillus reuteri Strains: Advances, Challenges, and Perspectives.

    • 2026-02-24
    • Review
    • Comprehensive reviews in food science and food safety 25(2)
    • • León-Espinosa Erika Berenice
      • Barrios-Francisco Rigoberto
      • Colin-Molina Abraham
      • Martínez-Palma Nikte Yoliztli
      • Rentería-Ortega Minerva

    • PubMed: 41732827
    • DOI: 10.1111/1541-4337.70412

    4 Insights on

    • Improved Gastrointestinal Health
    • Improved Metabolic Function
    • Reduced Inflammation
    • Improved Blood Lipid Profile

    • Low evidence

  • Targeting the gut microbiota: the application and prospects of probiotics, fecal microbiota transplantation, and natural products in MASLD.

    • 2026-02-24
    • Review
    • Frontiers in nutrition 13
    • • Mengtian Li
      • Haoyu Zhai
      • Liping Qiao
      • Zhaobo Wang
      • Liyang Yang
      • Xinrui Zheng
      • Haoran Shi
      • Wenwen Geng
      • Jia Wang

    • PubMed: 41816239
    • DOI: 10.3389/fnut.2026.1735669

    3 Insights on

    • Improved Gut Microbiota Composition
    • Reduced Inflammatory Markers
    • Improved Metabolic Parameters

    • Low evidence
• February 26

  • Probiotics and Phytoantioxidants as Emerging Neuroprotective Strategies: Bridging the Therapeutic Gap in Open Heart Surgery-Induced Brain Injury.

    • 2026-02-26
    • Review
    • Biomedicines 14(3)
    • • Yen Chu
      • Kuo-Hsiung Huang
      • Chi-Nan Tseng

    • PubMed: 41898174
    • DOI: 10.3390/biomedicines14030527

    5 Insights on

    • Improved Cognitive Function
    • Reduced Neuroinflammation
    • Reduced Oxidative Stress
    • Improved Neuroprotection
    • Improved Neuronal Survival

    • Low evidence

  • From Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke.

    • 2026-02-26
    • Review
    • Current nutrition reports 15(1)
    • • Nevin Sanlier
      • Ebru Ozler

    • PubMed: 41741921
    • DOI: 10.1007/s13668-025-00722-4

    5 Insights on

    • Improved Bowel Movement Frequency
    • Reduced Blood Pressure
    • Reduced Cancer Risk
    • Reduced Blood Glucose Levels
    • Reduced Total Cholesterol

    • Low evidence

  • Screening of probiotics for promoting mineral absorption based on in vitro fermentation and cell models.

    • 2026-02-26
    • Frontiers in microbiology 17
    • • Bin Liu
      • Yuejian Mao
      • Jing Yang
      • Linjun Wu
      • Xiaoqiong Li
      • Xiangyu Bian
      • Jian Kuang
      • Jianqiang Li
      • Fangshu Shi
      • Ying Luo
      • Peiqing Jiang
      • Jinjun Li
      • Haibiao Sun

    • PubMed: 41834858
    • DOI: 10.3389/fmicb.2026.1743657

    4 Insights on

    • Improved Iron Absorption
    • Improved Calcium Absorption
    • Improved Mineral Absorption
    • Improved Zinc Absorption

    • Low evidence

  • Evaluation of the delivery of an anti-Listeria endolysin via CRISPR-Cas9 engineered probiotic Saccharomyces boulardii.

    • 2026-02-26
    • Applied microbiology and biotechnology 110(1)
    • • David Sáez Moreno
      • João Paulo Carvalho
      • Ellen Murray
      • Natalia Soledad Ríos Colombo
      • Alexandre Lamas
      • Alejandra Cardelle Cobas
      • Colin Hill
      • Joana Azeredo
      • Lucília Domingues

    • PubMed: 41748831
    • DOI: 10.1007/s00253-026-13749-6

    3 Insights on

    • Reduced Listeria Monocytogenes Population
    • Reduced Listeria Colonization
    • Reduced Anti-Listeria Effect

    • Low evidence

  • Effects of probiotic supplementation on immune and inflammatory markers in athletes: an umbrella review and re-analysis of published meta-analyses of randomised controlled trials.

    • 2026-02-26
    • Meta-Analysis · n = 413
    • PeerJ 14
    • • Lei Chen
      • Aichun Li
      • Wenhao Chen
      • Junlai Zhou
      • Yujia Kou

    • PubMed: 41773190
    • DOI: 10.7717/peerj.20809

    9 Insights on

    • Reduced Tumor Necrosis Factor Alpha
    • Increased Interferon-Gamma Levels
    • Reduced Inflammation
    • Increased Secretory Immunoglobulin A
    • Reduced Pro-Inflammatory Factor TNF-α
    • Improved Mucosal Immunity
    • No Meaningful Change in IL-6
    • No Meaningful Change in IL-8
    • No Meaningful Change in IL-10

    • High evidence
    • Rigorous Journal

  • Overview of the immunomodulatory role of bacterial probiotic-derived peptidoglycan: from molecular insights to therapeutic application.

    • 2026-02-26
    • Review
    • Frontiers in microbiology 17
    • • Omer Qutaiba B Allela
      • Abdulkareem Shareef
      • Hayder Naji Sameer
      • Ahmed Yaseen
      • Zainab H Athab
      • Mohaned Adil

    • PubMed: 41834851
    • DOI: 10.3389/fmicb.2026.1761985

    8 Insights on

    • Improved Immune Function
    • Reduced Inflammatory Response
    • Improved Immunomodulation
    • Modulated Immune Response
    • Reduced Inflammation
    • Improved Immune Modulation
    • Improved Effectiveness in Inflammatory Bowel Disease
    • Reduced Inflammatory Bowel Disease Symptoms

    • Low evidence
• February 27

  • Active folates and choline in prenatal development: current recommendations and clinical implications.

    • 2026-02-27
    • Review
    • Ginekologia polska 97(2)
    • • Aleksandra Krupa
      • Violetta Skrzypulec-Plinta

    • PubMed: 41432531
    • DOI: 10.5603/gpl.105802

    1 Insight on

    • Reduced Obesity

    • Low evidence

  • Is the Juice Worth the Squeeze? Vitamin C Supplementation in Hemodialysis Patients: A Systematic Review.

    • 2026-02-27
    • Systematic Review
    • Nutrients 18(5)
    • • Małgorzata Sikorska-Wiśniewska
      • Magdalena Jankowska
      • Leszek Tylicki
      • Alicja Dębska-Ślizień

    • PubMed: 41829943
    • DOI: 10.3390/nu18050774

    2 Insights on

    • Reduced Functional Iron Deficiency
    • Reduced Restless Legs Syndrome Symptoms

    • High evidence
    • Rigorous Journal

  • Development of novel microbial synthetic consortia for the production of antimicrobial fermentates containing caproate.

    • 2026-02-27
    • Applied microbiology and biotechnology 110(1)
    • • Maria Florencia Bambace
      • Ker Sin Ng
      • Kirsten Wiborg Jensen
      • Adrien Schneider
      • Mensure Elvan Gezer
      • Angeliki Marietou
      • Aviaja Kristiansen Aarseth
      • Annika Regnet
      • Kathrine Gravlund Fønss
      • Ulrik Kræmer Sundekilde
      • Clarissa Schwab

    • PubMed: 41760812
    • DOI: 10.1007/s00253-026-13718-z

    3 Insights on

    • Improved Antimicrobial Ability
    • Reduced Microbial Growth
    • Improved Biopreservation Potential

    • Low evidence

  • Role of probiotic supplementation in preventing ventilator-associated pneumonia among critically ill patients-a critical umbrella review of meta-analyses of randomized controlled trials.

    • 2026-02-27
    • Systematic Review
    • Frontiers in nutrition 12
    • • Yan Jiang
      • Dan Xiao
      • Jixin Zhou
      • Fengpei Zhang
      • Zhiteng Xiong
      • Qihui Shen
      • Xiaoyun Xiong

    • PubMed: 41834846
    • DOI: 10.3389/fnut.2025.1719310

    9 Insights on

    • Reduced Pediatric Intensive Care Unit Stay
    • Reduced Hospital Mortality Rate
    • Reduced Length of Hospital Stay
    • Reduced Diarrhea
    • Reduced Nosocomial Infection Rate
    • Reduced Antibiotic Use
    • Reduced Ventilator-Associated Pneumonia
    • Reduced Duration of Mechanical Ventilation
    • Reduced Intensive Care Unit Mortality

    • High evidence

  • From Dysbiosis to Inflammation: Gut Microbiota and Oxidative Stress in Atopic Dermatitis.

    • 2026-02-27
    • Review
    • Antioxidants (Basel, Switzerland) 15(3)
    • • Patrycja Lipska
      • Kamila Łukańko
      • Julia Sobczak
      • Ivanna Lazarchuk
      • Anna Duda-Madej

    • PubMed: 41897446
    • DOI: 10.3390/antiox15030299

    2 Insights on

    • Improved Atopic Dermatitis Symptoms
    • Improved Gastrointestinal Symptoms

    • Low evidence
• February 28

  • Nutritional Status in Obesity: A Comprehensive Narrative Review of Dysbiosis, Micronutrient Deficiencies and the Effects of Probiotics/Synbiotics.

    • 2026-02-28
    • Review
    • Medicina (Kaunas, Lithuania) 62(3)
    • • Andra-Diana Cecan
      • Adriana-Florinela Cătoi
      • Anca But
      • Iulia-Ioana Morar

    • PubMed: 41901543
    • DOI: 10.3390/medicina62030458

    3 Insights on

    • Reduced Body Weight
    • Improved Metabolic Function
    • Improved Gut Microbiota Balance

    • Low evidence

  • Gut-Centric Multi-System Regulation by Bacillus subtilis and Bacillus natto: A Review of Their Probiotic Functions in Nutrition, Immunity, and Metabolism.

    • 2026-02-28
    • Systematic Review
    • Nutrients 18(5)
    • • Mei Hua
      • Jing Wang
      • Yueqiao Li
      • Yuguang He
      • Zhengyang Luo
      • Da Li
      • Mubai Sun
      • Xinyu Miao
      • Honghong Niu
      • Tong Pan
      • Jinghui Wang
      • Chengshan Wan

    • PubMed: 41829972
    • DOI: 10.3390/nu18050802

    7 Insights on

    • Improved Intestinal Barrier Function
    • Improved Calcium Absorption
    • Improved Bowel Function
    • Reduced Liver Injury
    • Improved Insulin Resistance
    • Improved Digestive Efficiency
    • Improved Metabolic Homeostasis

    • High evidence
    • Rigorous Journal

  • Pre-, Pro-, Post- and Synbiotics in Pediatric Short Bowel Syndrome: A Narrative Review of Current Evidence.

    • 2026-02-28
    • Review
    • Children (Basel, Switzerland) 13(3)
    • • Roberta Giusy Ruiz
      • Annalisa Morelli
      • Rosangela Grieco
      • Sabrina Cardile
      • Teresa Capriati
      • Chiara Maria Trovato
      • Giulia Bolasco
      • Daniela Knafelz
      • Fiammetta Bracci
      • Arianna Alterio
      • Antonella Diamanti

    • PubMed: 41897062
    • DOI: 10.3390/children13030349

    3 Insights on

    • Reduced Postoperative Infectious Complications
    • Increased Risk of Sepsis
    • Reduced D-Lactic Acidosis

    • Low evidence
• Undated – 14 supplement studies

  • Effects of Peanut Butter Supplementation on Older Adults' Physical Function: A 6-Month Randomised Controlled Trial.

    • 2026-02
    • RCT · n = 108
    • Journal of cachexia, sarcopenia and muscle 17(1)
    • • Ilili Feyesa
      • Jeew Hettiarachchi
      • Robin M Daly
      • Elena S George
      • Ekavi N Georgousopoulou
      • David Scott
      • Brenton J Baguley
      • Gavin Abbott
      • Sze-Yen Tan

    • PubMed: 41632974
    • DOI: 10.1002/jcsm.70221

    2 Insights on

    • Improved Five Times Sit-to-Stand Time
    • Improved Muscle Power

    • High evidence
    • Large Human Trial

  • Innovative co-fermentation of Propionibacterium freudenreichii and Rhizopus oryzae enhances vitamin B12, riboflavin, and flavor profile components in sweet fermented glutinous rice.

    • 2026-02
    • Food chemistry 503
    • • Ruoxi Zhang
      • Liye Chen
      • Dongming Zhang
      • Jenni Sihvola
      • Bhawani Chamlagain
      • Miikka Olin
      • Vieno Piironen
      • Pekka Varmanen

    • PubMed: 41483792
    • DOI: 10.1016/j.foodchem.2025.147815

    2 Insights on

    • Increased Antioxidant Capacity
    • Enhanced Sensory Perception

    • Low evidence

  • Synbiotic intervention with Bifidobacterium bifidum and prebiotics reduces enterohemorrhagic Escherichia coli colonization.

    • 2026-02
    • Letters in applied microbiology 79(2)
    • • Wanqiu Sha
      • Anqi Su
      • Hong Cheng
      • Ning Dong
      • Jia Fu
      • Liang Zhu
      • Guoqing Tao
      • Yunxin Xue
      • Hongwei Cui
      • Dai Wang

    • PubMed: 41636800
    • DOI: 10.1093/lambio/ovag019

    1 Insight on

    • Reduced Enterohemorrhagic Escherichia coli Colonization

    • Low evidence

  • Lactobacillus delbrueckii: A Functional Powerhouse in Dairy Fermentation and Emerging Probiotic Applications.

    • 2026-02
    • Review
    • Food science & nutrition 14(2)
    • • Yousef Nami
      • Anahita Barghi
      • Mahsa Sadeghi
      • Tara Farhadi
      • Babak Haghshenas

    • PubMed: 41710811
    • DOI: 10.1002/fsn3.71546

    3 Insights on

    • Improved Gut Health
    • Reduced Cancer Risk
    • Reduced Total Cholesterol

    • Low evidence

  • Bioactive Phenolic Compounds in Extra Virgin Olive Oil: Implications for Cardiovascular Health.

    • 2026-02
    • Review
    • Food science & nutrition 14(2)
    • • Cristina Vázquez-Jiménez
      • Mª Dolores Rodríguez-Pérez
      • Laura Ortega-Hombrados
      • Ana María Sánchez-Tévar
      • José Pedro de la Cruz-Cortés
      • José A Gonzalez-Correa

    • PubMed: 41695108
    • DOI: 10.1002/fsn3.71441

    4 Insights on

    • Reduced Blood Pressure
    • Reduced Inflammatory Markers
    • Improved Vascular Endothelial Function
    • Improved Blood Lipid Profile

    • Low evidence

  • Bifidobacterium Breve SHMB 8001 Alleviates DSS-Induced Colitis in Mice Via Modulating the Intestinal Barrier and Gut Microbiota.

    • 2026-02
    • Journal of food science 91(2)
    • • Gaojie Liu
      • Xufei Wang
      • Yan Hao
      • Lewen Tu
      • Yongchao Mei
      • Ting Zhang
      • Yizhong Wang

    • PubMed: 41645793
    • DOI: 10.1111/1750-3841.70903

    4 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Colitis Severity
    • Increased Short-Chain Fatty Acid Production
    • Increased Regulatory T Cell Count

    • Low evidence
    • Rigorous Journal

  • Effect of vitamin E supplementation on recovery and recurrence prevention in women with lower urinary tract infections: A triple-blind randomized clinical trial.

    • 2026-02
    • RCT
    • Clinical nutrition ESPEN 71
    • • Hajar Mafakher
      • Azadeh Ebrahimzadeh
      • Adeleh Sahebnasagh
      • Melika Ramezani
      • Razieh Avan

    • PubMed: 41390063
    • DOI: 10.1016/j.clnesp.2025.102876

    4 Insights on

    • Reduced Infection Recurrence
    • Improved Urinary Frequency
    • Improved Dysuria
    • Reduced Recovery Time

    • High evidence

  • Streptococcus thermophilus: A next-generation chassis for customizing exopolysaccharide with rare sugar.

    • 2026-02
    • Review
    • Food research international (Ottawa, Ont.) 226
    • • Mengshi Xiao
      • Jiuxiang Nie
      • Xiaodan Fu
      • Lin Zhang
      • Haijin Mou
      • Qiuhong Niu

    • PubMed: 41539799
    • DOI: 10.1016/j.foodres.2025.118150

    2 Insights on

    • Improved Bioactivity
    • Increased Bioactivity

    • Low evidence

  • Lactobacillus delbrueckii surface protein P4430 attenuates intestinal inflammation by modulating macrophage polarization via Mincle.

    • 2026-02
    • Cell reports 45(2)
    • • Xiangyu Zhang
      • Xiangyi Zeng
      • Yujun Wu
      • Xiaoyi Liu
      • Xu Lin
      • Hao Wang
      • Yisi Liu
      • Luyuan Kang
      • Zhenyu Wang
      • Dongdong Lu
      • Xiaomei Liu
      • Guanhong Yue
      • Tengfei Lv
      • Shiyu Tao
      • Jinbiao Zhao
      • Zhaolai Dai
      • Guolong Zhang
      • Junjun Wang
      • Dandan Han

    • PubMed: 41569848
    • DOI: 10.1016/j.celrep.2025.116869

    2 Insights on

    • Reduced Intestinal Inflammation
    • Improved Colitis Symptoms

    • Low evidence

  • Lactobacillus reuteri DSM 17938 Improves Intestinal Motility in Mice With Postoperative Ileus by Modulating Gut Microbiota and Macrophage.

    • 2026-02
    • Neurogastroenterology and motility 38(2)
    • • Jingyi Tang
      • Yingnan Hu
      • Dian Yu
      • Baoqing Liu
      • Wenjun Xu
      • Weihan Zhu
      • Yanting Xia
      • Zhipeng Zheng
      • Wei Zhang

    • PubMed: 41672915
    • DOI: 10.1111/nmo.70260

    2 Insights on

    • Reduced Inflammatory Response
    • Improved Intestinal Motility

    • Low evidence
    • Animal Study

  • Interventions Targeting the Gut Microbiome to Improve Cancer Treatment Outcomes and Their Gastrointestinal Side Effects: A Systematic Review and Meta-analysis.

    • 2026-02
    • Meta-Analysis · n = 37
    • The Journal of nutrition 156(2)
    • • Cecilia Morel
      • Ruijie Li
      • Carmen Fiuza Luces
      • Mark Fh Brougham
      • Juan Francisco Pascual-Gazquez
      • Luciana Torquati
      • Raquel Revuelta Iniesta

    • PubMed: 41475679
    • DOI: 10.1016/j.tjnut.2025.101300

    4 Insights on

    • Improved Treatment Response Rate
    • Reduced Gastrointestinal Adverse Events
    • No Improvement in Objective Cancer Treatment Response
    • Improved Cancer Treatment Tolerance

    • High evidence

  • Lactobacillus helveticus R0052-derived membrane vesicles ameliorate DSS-induced inflammatory bowel disease by modulating the gut microbiota and activating the cholinergic anti-inflammatory pathway.

    • 2026-02
    • International immunopharmacology 171
    • • Chinasa Valerie Olovo
      • Ying Ji
      • Dickson Kofi Wiredu Ocansey
      • Xinxiang Huang
      • Min Xu

    • PubMed: 41512794
    • DOI: 10.1016/j.intimp.2025.116058

    4 Insights on

    • Improved Gut Microbiota Composition
    • Improved Intestinal Barrier Function
    • Reduced Colitis Severity
    • Increased Acetylcholine Levels

    • Low evidence
    • Animal Study

  • Hepatoprotective Potential of Indian Medicinal Plants.

    • 2026-02
    • Review
    • Combinatorial chemistry & high throughput screening 29(3)
    • • Arti Kumari
      • Nisha Chandila
      • Rubina Bhutani
      • Inderjeet Yadav

    • PubMed: 39835553
    • DOI: 10.2174/0113862073346295250107070310

    1 Insight on

    • Reduced Liver Enzyme Levels

    • Low evidence

  • Oral vaccination via virus-like particles encapsulated in Lactococcus lactis.

    • 2026-02
    • Clinical Trial
    • Fish & shellfish immunology 169
    • • Hui Yee Hong
      • Lee Ching Pei Carmen
      • Pin Xuan Chee
      • Lim Xin Ying
      • Zhi Wei Wong
      • Janlin Chan
      • Mookkan Prabakaran
      • Daiwen Yang

    • PubMed: 41519596
    • DOI: 10.1016/j.fsi.2025.111013

    2 Insights on

    • Reduced Viral Load
    • Improved Specific Antibody Response

    • Low evidence
    • Animal Study